Nihar Kinarivala

Affiliations

Program in Chemical Biology, Sloan Kettering Institute, New York, NY 10065, United States.

Publications (10)

Multi-Targeting Anticancer Agents: Rational Approaches, Synthetic Routes and Structure Activity Relationship.

Anti-cancer agents in medicinal chemistry

Avec: Harbinder Singh , Nihar Kinarivala , Sahil Sharma

Tailored Quinolines Demonstrate Flexibility to Exert Antitumor Effects through Varied Mechanisms-A Medicinal Perspective.

Anti-cancer agents in medicinal chemistry

Avec: Sachin Sharma , Arshdeep Singh , Sahil Sharma , Ram Sharma , Jagjeet Singh , Nihar Kinarivala , Kunal Nepali , Jing P Liou

Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes.

Methods in enzymology

Avec: Nihar Kinarivala , Lisa C Standke , Tezcan Guney , Cheng Ji , Naoyoshi Noguchi , Yasutomi Asano , Derek S Tan

Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability.

Journal of medicinal chemistry

Avec: Md Shafikur Rahman , Shikha Kumari , Shiva Hadi Esfahani , Saeideh Nozohouri , Srinidhi Jayaraman , Nihar Kinarivala , Joanna Kocot , Andrew Baez , Delaney Farris , Thomas J Abbruscato , Vardan T Karamyan , Paul C Trippier

Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics.

Antimicrobial agents and chemotherapy

Avec: Inga V Leus , Justyna Adamiak , Brinda Chandar , Vincent Bonifay , Shibin Zhao , Scott S Walker , Brian Squadroni , Carl J Balibar , Nihar Kinarivala , Lisa C Standke , Henning U Voss , Derek S Tan , Valentin V Rybenkov , Helen I Zgurskaya

Rational approaches, design strategies, structure activity relationship and mechanistic insights for therapeutic coumarin hybrids.

Bioorganic & medicinal chemistry

Avec: Harbinder Singh , Jatinder Vir Singh , Kavita Bhagat , Harmandeep Kaur Gulati , Mohit Sanduja , Nitish Kumar , Nihar Kinarivala , Sahil Sharma

Rational approaches for the design of various GABA modulators and their clinical progression.

Molecular diversity

Avec: Kavita Bhagat , Jatinder V Singh , Piyusha P Pagare , Nitish Kumar , Anchal Sharma , Gurinder Kaur , Nihar Kinarivala , Srinivasa Gandu , Harbinder Singh , Sahil Sharma , Preet Mohinder S Bedi

An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening.

ACS pharmacology & translational science

Avec: Nihar Kinarivala , Ahmed Morsy , Ronak Patel , Angelica V Carmona , Md Sanaullah Sajib , Snehal Raut , Constantinos M Mikelis , Abraham Al-Ahmad , Paul C Trippier

Exogenous Flupirtine as Potential Treatment for CLN3 Disease.

Cells

Avec: Katia Maalouf , Joelle Makoukji , Sara Saab , Nadine J Makhoul , Angelica V Carmona , Nihar Kinarivala , Noël Ghanem , Paul C Trippier , Rose-Mary Boustany

Engineering CAR-T cells to activate small-molecule drugs in situ.

Nature chemical biology

Avec: Thomas J Gardner , J Peter Lee , Christopher M Bourne , Dinali Wijewarnasuriya , Nihar Kinarivala , Keifer G Kurtz , Broderick C Corless , Megan M Dacek , Aaron Y Chang , George Mo , Kha M Nguyen , Renier J Brentjens , Derek S Tan , David A Scheinberg

Réseau de co-auteurs

Sahil Sharma 4 collaborations

Harbinder Singh 3 collaborations

Derek S Tan 3 collaborations

Paul C Trippier 3 collaborations

Lisa C Standke 2 collaborations

Kavita Bhagat 2 collaborations

Nitish Kumar 2 collaborations

Angelica V Carmona 2 collaborations

Sachin Sharma 1 collaboration

Arshdeep Singh 1 collaboration

Ram Sharma 1 collaboration

Jagjeet Singh 1 collaboration

Kunal Nepali 1 collaboration

Jing P Liou 1 collaboration

Tezcan Guney 1 collaboration

Cheng Ji 1 collaboration

Naoyoshi Noguchi 1 collaboration

Yasutomi Asano 1 collaboration

Md Shafikur Rahman 1 collaboration

Shikha Kumari 1 collaboration

Shiva Hadi Esfahani 1 collaboration

Saeideh Nozohouri 1 collaboration

Srinidhi Jayaraman 1 collaboration

Joanna Kocot 1 collaboration

Andrew Baez 1 collaboration

Delaney Farris 1 collaboration

Thomas J Abbruscato 1 collaboration

Vardan T Karamyan 1 collaboration

Inga V Leus 1 collaboration

Justyna Adamiak 1 collaboration

Brinda Chandar 1 collaboration

Vincent Bonifay 1 collaboration

Shibin Zhao 1 collaboration

Scott S Walker 1 collaboration

Brian Squadroni 1 collaboration

Carl J Balibar 1 collaboration

Henning U Voss 1 collaboration

Valentin V Rybenkov 1 collaboration

Helen I Zgurskaya 1 collaboration

Jatinder Vir Singh 1 collaboration

Harmandeep Kaur Gulati 1 collaboration

Mohit Sanduja 1 collaboration

Jatinder V Singh 1 collaboration

Piyusha P Pagare 1 collaboration

Anchal Sharma 1 collaboration

Gurinder Kaur 1 collaboration

Srinivasa Gandu 1 collaboration

Preet Mohinder S Bedi 1 collaboration

Ahmed Morsy 1 collaboration

Ronak Patel 1 collaboration

Md Sanaullah Sajib 1 collaboration

Snehal Raut 1 collaboration

Constantinos M Mikelis 1 collaboration

Abraham Al-Ahmad 1 collaboration

Katia Maalouf 1 collaboration

Joelle Makoukji 1 collaboration

Sara Saab 1 collaboration

Nadine J Makhoul 1 collaboration

Noël Ghanem 1 collaboration

Rose-Mary Boustany 1 collaboration

Thomas J Gardner 1 collaboration

J Peter Lee 1 collaboration

Christopher M Bourne 1 collaboration

Dinali Wijewarnasuriya 1 collaboration

Keifer G Kurtz 1 collaboration

Broderick C Corless 1 collaboration

Megan M Dacek 1 collaboration

Aaron Y Chang 1 collaboration

George Mo 1 collaboration

Kha M Nguyen 1 collaboration

Renier J Brentjens 1 collaboration

David A Scheinberg 1 collaboration