Nicole S Persky

Affiliations

Cancer Program, The Broad Institute of M.I.T. and Harvard, Cambridge, MA, USA.
Genetic Perturbation Platform, The Broad Institute of M.I.T. and Harvard, Cambridge, MA, USA.
Aera Therapeutics, Cambridge, MA, USA.

Publications (10)

Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants.

Nature communications

Avec: Tikvah K Hayes , Elisa Aquilanti , Nicole S Persky , Xiaoping Yang , Erica E Kim , Lisa Brenan , Amy B Goodale , Douglas Alan , Ted Sharpe , Robert E Shue , Lindsay Westlake , Lior Golomb , Brianna R Silverman , Myshal D Morris , Ty Running Fisher , Eden Beyene , Yvonne Y Li , Andrew D Cherniack , Federica Piccioni , J Kevin Hicks , Andrew S Chi , Daniel P Cahill , Jorg Dietrich , Tracy T Batchelor , David E Root , Cory M Johannessen , Matthew Meyerson

Acquired HER2 mutations in ER

Nature genetics

Avec: Utthara Nayar , Ofir Cohen , Christian Kapstad , Michael S Cuoco , Adrienne G Waks , Seth A Wander , Corrie Painter , Samuel Freeman , Nicole S Persky , Lori Marini , Karla Helvie , Nelly Oliver , Orit Rozenblatt-Rosen , Cynthia X Ma , Aviv Regev , Eric P Winer , Nancy U Lin , Nikhil Wagle

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes.

Cancer research

Avec: Yeying Huang , R Taylor Durall , Nhi M Luong , Hans J Hertzler , Julianna Huang , Prafulla C Gokhale , Brittaney A Leeper , Nicole S Persky , David E Root , Praju V Anekal , Paula D L M Montero Llopis , Clement N David , Jeffery L Kutok , Alejandra Raimondi , Karan Saluja , Jia Luo , Cynthia A Zahnow , Biniam Adane , Kimberly Stegmaier , Catherine E Hawkins , Christopher Ponne , Quan Le , Geoffrey I Shapiro , Madeleine E Lemieux , Kyle P Eagen , Christopher A French

Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.

Nature

Avec: Jason J Kwon , Behnoush Hajian , Yuemin Bian , Lucy C Young , Alvaro J Amor , James R Fuller , Cara V Fraley , Abbey M Sykes , Jonathan So , Joshua Pan , Laura Baker , Sun Joo Lee , Douglas B Wheeler , David L Mayhew , Nicole S Persky , Xiaoping Yang , David E Root , Anthony M Barsotti , Andrew W Stamford , Charles K Perry , Alex Burgin , Frank McCormick , Christopher T Lemke , William C Hahn , Andrew J Aguirre

Total loss of

Proceedings of the National Academy of Sciences of the United States of America

Avec: Muhannad Abu-Remaileh , Nicole S Persky , Yenarae Lee , David E Root , William G Kaelin

Genetic screens in isogenic mammalian cell lines without single cell cloning.

Nature communications

Avec: Peter C DeWeirdt , Annabel K Sangree , Ruth E Hanna , Kendall R Sanson , Mudra Hegde , Christine Strand , Nicole S Persky , John G Doench

CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines.

Genome medicine

Avec: Daniel J Merk , Linda Paul , Foteini Tsiami , Helen Hohenthanner , Ghazal Mohseni Kouchesfahani , Lara A Haeusser , Bianca Walter , Adam Brown , Nicole S Persky , David E Root , Ghazaleh Tabatabai

Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases.

Nature structural & molecular biology

Avec: N S Persky , D Hernandez , M Do Carmo , L Brenan , O Cohen , S Kitajima , U Nayar , A Walker , S Pantel , Y Lee , J Cordova , M Sathappa , C Zhu , T K Hayes , P Ram , P Pancholi , T S Mikkelsen , D A Barbie , X Yang , R Haq , F Piccioni , D E Root , C M Johannessen

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Joana Damas , Graham M Hughes , Kathleen C Keough , Corrie A Painter , Nicole S Persky , Marco Corbo , Michael Hiller , Klaus-Peter Koepfli , Andreas R Pfenning , Huabin Zhao , Diane P Genereux , Ross Swofford , Katherine S Pollard , Oliver A Ryder , Martin T Nweeia , Kerstin Lindblad-Toh , Emma C Teeling , Elinor K Karlsson , Harris A Lewin

Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates.

bioRxiv : the preprint server for biology

Avec: Joana Damas , Graham M Hughes , Kathleen C Keough , Corrie A Painter , Nicole S Persky , Marco Corbo , Michael Hiller , Klaus-Peter Koepfli , Andreas R Pfenning , Huabin Zhao , Diane P Genereux , Ross Swofford , Katherine S Pollard , Oliver A Ryder , Martin T Nweeia , Kerstin Lindblad-Toh , Emma C Teeling , Elinor K Karlsson , Harris A Lewin

Réseau de co-auteurs

David E Root 5 collaborations

Xiaoping Yang 2 collaborations

Joana Damas 2 collaborations

Graham M Hughes 2 collaborations

Kathleen C Keough 2 collaborations

Corrie A Painter 2 collaborations

Marco Corbo 2 collaborations

Michael Hiller 2 collaborations

Klaus-Peter Koepfli 2 collaborations

Andreas R Pfenning 2 collaborations

Huabin Zhao 2 collaborations

Diane P Genereux 2 collaborations

Ross Swofford 2 collaborations

Katherine S Pollard 2 collaborations

Oliver A Ryder 2 collaborations

Martin T Nweeia 2 collaborations

Kerstin Lindblad-Toh 2 collaborations

Emma C Teeling 2 collaborations

Elinor K Karlsson 2 collaborations

Harris A Lewin 2 collaborations

Tikvah K Hayes 1 collaboration

Elisa Aquilanti 1 collaboration

Erica E Kim 1 collaboration

Lisa Brenan 1 collaboration

Amy B Goodale 1 collaboration

Douglas Alan 1 collaboration

Ted Sharpe 1 collaboration

Robert E Shue 1 collaboration

Lindsay Westlake 1 collaboration

Lior Golomb 1 collaboration

Brianna R Silverman 1 collaboration

Myshal D Morris 1 collaboration

Ty Running Fisher 1 collaboration

Eden Beyene 1 collaboration

Yvonne Y Li 1 collaboration

Andrew D Cherniack 1 collaboration

Federica Piccioni 1 collaboration

J Kevin Hicks 1 collaboration

Andrew S Chi 1 collaboration

Daniel P Cahill 1 collaboration

Jorg Dietrich 1 collaboration

Tracy T Batchelor 1 collaboration

Cory M Johannessen 1 collaboration

Matthew Meyerson 1 collaboration

Utthara Nayar 1 collaboration

Ofir Cohen 1 collaboration

Christian Kapstad 1 collaboration

Michael S Cuoco 1 collaboration

Adrienne G Waks 1 collaboration

Seth A Wander 1 collaboration

Corrie Painter 1 collaboration

Samuel Freeman 1 collaboration

Lori Marini 1 collaboration

Karla Helvie 1 collaboration

Nelly Oliver 1 collaboration

Orit Rozenblatt-Rosen 1 collaboration

Cynthia X Ma 1 collaboration

Aviv Regev 1 collaboration

Eric P Winer 1 collaboration

Nancy U Lin 1 collaboration

Nikhil Wagle 1 collaboration

Yeying Huang 1 collaboration

R Taylor Durall 1 collaboration

Nhi M Luong 1 collaboration

Hans J Hertzler 1 collaboration

Julianna Huang 1 collaboration

Prafulla C Gokhale 1 collaboration

Brittaney A Leeper 1 collaboration

Praju V Anekal 1 collaboration

Paula D L M Montero Llopis 1 collaboration

Clement N David 1 collaboration

Jeffery L Kutok 1 collaboration

Alejandra Raimondi 1 collaboration

Karan Saluja 1 collaboration

Jia Luo 1 collaboration

Cynthia A Zahnow 1 collaboration

Biniam Adane 1 collaboration

Kimberly Stegmaier 1 collaboration

Catherine E Hawkins 1 collaboration

Christopher Ponne 1 collaboration

Quan Le 1 collaboration

Geoffrey I Shapiro 1 collaboration

Madeleine E Lemieux 1 collaboration

Kyle P Eagen 1 collaboration

Christopher A French 1 collaboration

Jason J Kwon 1 collaboration

Behnoush Hajian 1 collaboration

Yuemin Bian 1 collaboration

Lucy C Young 1 collaboration

Alvaro J Amor 1 collaboration

James R Fuller 1 collaboration

Cara V Fraley 1 collaboration

Abbey M Sykes 1 collaboration

Jonathan So 1 collaboration

Joshua Pan 1 collaboration

Laura Baker 1 collaboration

Sun Joo Lee 1 collaboration

Douglas B Wheeler 1 collaboration

David L Mayhew 1 collaboration

Anthony M Barsotti 1 collaboration

Andrew W Stamford 1 collaboration

Charles K Perry 1 collaboration

Alex Burgin 1 collaboration

Frank McCormick 1 collaboration

Christopher T Lemke 1 collaboration

William C Hahn 1 collaboration

Andrew J Aguirre 1 collaboration

Muhannad Abu-Remaileh 1 collaboration

Yenarae Lee 1 collaboration

William G Kaelin 1 collaboration

Peter C DeWeirdt 1 collaboration

Annabel K Sangree 1 collaboration

Ruth E Hanna 1 collaboration

Kendall R Sanson 1 collaboration

Mudra Hegde 1 collaboration

Christine Strand 1 collaboration

John G Doench 1 collaboration

Daniel J Merk 1 collaboration

Linda Paul 1 collaboration

Foteini Tsiami 1 collaboration

Helen Hohenthanner 1 collaboration

Ghazal Mohseni Kouchesfahani 1 collaboration

Lara A Haeusser 1 collaboration

Bianca Walter 1 collaboration

Adam Brown 1 collaboration

Ghazaleh Tabatabai 1 collaboration

N S Persky 1 collaboration

D Hernandez 1 collaboration

M Do Carmo 1 collaboration

L Brenan 1 collaboration

O Cohen 1 collaboration

S Kitajima 1 collaboration

U Nayar 1 collaboration

A Walker 1 collaboration

S Pantel 1 collaboration

Y Lee 1 collaboration

J Cordova 1 collaboration

M Sathappa 1 collaboration

C Zhu 1 collaboration

T K Hayes 1 collaboration

P Ram 1 collaboration

P Pancholi 1 collaboration

T S Mikkelsen 1 collaboration

D A Barbie 1 collaboration

X Yang 1 collaboration

R Haq 1 collaboration

F Piccioni 1 collaboration

D E Root 1 collaboration

C M Johannessen 1 collaboration