Nathaniel L Elsen

Affiliations

AbbVie Inc, 1 North Waukegan Rd., North Chicago, Illinois 60064, United States.

Publications (13)

High-Throughput Intact Protein Analysis for Drug Discovery Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry.

Analytical chemistry

Avec: Fan Pu , Scott A Ugrin , Andrew J Radosevich , David Chang-Yen , James W Sawicki , Nari N Talaty , Nathaniel L Elsen , Jon D Williams

Inhibition of MALT1 and BCL2 induces synergistic anti-tumor activity in models of B cell lymphoma.

Molecular cancer therapeutics

Avec: Joshua P Plotnik , Adam E Richardson , Haopeng Yang , Estela Rojas , Velitchka Bontcheva , Colleen Dowell , Sydney Parsons , Ashley Wilson , Vida Ravanmehr , Christine Will , Paul Jung , Haizhong Zhu , Sarathy Karunan Partha , Sanjay C Panchal , Raghuveer Singh Mali , Frederick J Kohlhapp , Ryan A McClure , Cyril Y Ramathal , Mariam D George , Manisha Jhala , Nathaniel L Elsen , Wei Qiu , Russell A Judge , Chin Pan , Anthony Mastracchio , Jared Henderson , Jonathan A Meulbroek , Michael R Green , William N Pappano

Next-Generation Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Source for Mass Spectrometry Imaging and High-Throughput Screening.

Journal of the American Society for Mass Spectrometry

Avec: Kevan T Knizner , Jacob P Guymon , Kenneth P Garrard , Guy Bouvrée , Jeffrey Manni , Jan-Peter Hauschild , Kerstin Strupat , Kyle L Fort , Lee Earley , Eloy R Wouters , Fan Pu , Andrew J Radosevich , Nathaniel L Elsen , Jon D Williams , Mark R Pankow , David C Muddiman

Ultra-high-throughput mass spectrometry in drug discovery: fundamentals and recent advances.

Expert opinion on drug discovery

Avec: Jon D Williams , Fan Pu , James W Sawicki , Nathaniel L Elsen

Normalization techniques for high-throughput screening by infrared matrix-assisted laser desorption electrospray ionization mass spectrometry.

Journal of mass spectrometry : JMS

Avec: Kevan T Knizner , Michael C Bagley , Fan Pu , Nathaniel L Elsen , Jon D Williams , David C Muddiman

Ultra-High-Throughput Ambient MS: Direct Analysis at 22 Samples per Second by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry.

Analytical chemistry

Avec: Andrew J Radosevich , Fan Pu , David Chang-Yen , James W Sawicki , Nari N Talaty , Nathaniel L Elsen , Jon D Williams , Jeffrey Y Pan

New Platform for Label-Free, Proximal Cellular Pharmacodynamic Assays: Identification of Glutaminase Inhibitors Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry.

ACS chemical biology

Avec: Fan Pu , Andrew J Radosevich , Brett G Bruckner , David A Fontaine , Sanjay C Panchal , Jon D Williams , Sujatha M Gopalakrishnan , Nathaniel L Elsen

Detection of Noncovalent Protein-Ligand Complexes by IR-MALDESI-MS.

Journal of the American Society for Mass Spectrometry

Avec: Kevan T Knizner , Fan Pu , James W Sawicki , Andrew J Radosevich , Scott A Ugrin , Nathaniel L Elsen , Jon D Williams , David C Muddiman

High-Throughput Label-Free Biochemical Assays Using Infrared Matrix-Assisted Desorption Electrospray Ionization Mass Spectrometry.

Analytical chemistry

Avec: Fan Pu , Andrew J Radosevich , James W Sawicki , David Chang-Yen , Nari N Talaty , Sujatha M Gopalakrishnan , Jon D Williams , Nathaniel L Elsen

Emerging Chromatography-Free High-Throughput Mass Spectrometry Technologies for Generating Hits and Leads.

ACS medicinal chemistry letters

Avec: Fan Pu , Nathaniel L Elsen , Jon D Williams

Collaborative Robotics to Enable Ultra-High-Throughput IR-MALDESI.

SLAS technology

Avec: John Shanley , Fan Pu , Jon D Williams , Nathaniel L Elsen , Sujatha M Gopalakrishnan , Jeffrey Y Pan , Andrew J Radosevich

Optimized C-Trap Timing of an Orbitrap 240 Mass Spectrometer for High-Throughput Screening and Native MS by IR-MALDESI.

Journal of the American Society for Mass Spectrometry

Avec: Kevan T Knizner , Michael C Bagley , Kenneth P Garrard , Jan-Peter Hauschild , Fan Pu , Nathaniel L Elsen , Jon D Williams , David C Muddiman

High-Throughput Deconvolution of Intact Protein Mass Spectra for the Screening of Covalent Inhibitors.

Journal of the American Society for Mass Spectrometry

Avec: Fan Pu , Kevan T Knizner , Matthew T Robey , Andrew J Radosevich , Scott A Ugrin , Nathaniel L Elsen , Kenneth R Durbin , Jon D Williams

Réseau de co-auteurs

Fan Pu 12 collaborations

Jon D Williams 12 collaborations

Andrew J Radosevich 8 collaborations

James W Sawicki 5 collaborations

Kevan T Knizner 5 collaborations

David C Muddiman 4 collaborations

Scott A Ugrin 3 collaborations

David Chang-Yen 3 collaborations

Nari N Talaty 3 collaborations

Sujatha M Gopalakrishnan 3 collaborations

Sanjay C Panchal 2 collaborations

Kenneth P Garrard 2 collaborations

Jan-Peter Hauschild 2 collaborations

Michael C Bagley 2 collaborations

Jeffrey Y Pan 2 collaborations

Joshua P Plotnik 1 collaboration

Adam E Richardson 1 collaboration

Haopeng Yang 1 collaboration

Estela Rojas 1 collaboration

Velitchka Bontcheva 1 collaboration

Colleen Dowell 1 collaboration

Sydney Parsons 1 collaboration

Ashley Wilson 1 collaboration

Vida Ravanmehr 1 collaboration

Christine Will 1 collaboration

Paul Jung 1 collaboration

Haizhong Zhu 1 collaboration

Sarathy Karunan Partha 1 collaboration

Raghuveer Singh Mali 1 collaboration

Frederick J Kohlhapp 1 collaboration

Ryan A McClure 1 collaboration

Cyril Y Ramathal 1 collaboration

Mariam D George 1 collaboration

Manisha Jhala 1 collaboration

Wei Qiu 1 collaboration

Russell A Judge 1 collaboration

Chin Pan 1 collaboration

Anthony Mastracchio 1 collaboration

Jared Henderson 1 collaboration

Jonathan A Meulbroek 1 collaboration

Michael R Green 1 collaboration

William N Pappano 1 collaboration

Jacob P Guymon 1 collaboration

Guy Bouvrée 1 collaboration

Jeffrey Manni 1 collaboration

Kerstin Strupat 1 collaboration

Kyle L Fort 1 collaboration

Lee Earley 1 collaboration

Eloy R Wouters 1 collaboration

Mark R Pankow 1 collaboration

Brett G Bruckner 1 collaboration

David A Fontaine 1 collaboration

John Shanley 1 collaboration

Matthew T Robey 1 collaboration

Kenneth R Durbin 1 collaboration