From the Department of Neurology (A.H.O., C.Z., B.M.-S., M.L.F., B.R., R.J.N., K.C.O'C.), Yale School of Medicine, New Haven, CT; Department of Immunobiology (A.H.O., C.Z., M.L.F., W.M.P., K.C.O'C.), Yale School of Medicine, New Haven, CT; Institute of Biomedical Studies (A.H.O.), Baylor University, Waco, TX; UCB Pharma (D.D.V.), Cambridge, MA; and Departments of Neurology and Ophthalmology (J.L.B.), Programs in Neuroscience and Immunology, University of Colorado Anschutz Medical Campus, Aurora.