Mercedes Gonzalez-Juarrero

Affiliations

Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, 80523, USA. Electronic address: mercedes.gonzalez-juarrero@colostate.edu.

Publications (28)

Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies.

Tuberculosis (Edinburgh, Scotland)

Avec: Amanda Walz , Pradeep B Lukka , Camron Pearce , Elizabeth Creissen , Miriam Braunstein , Anthony J Hickey , Bernd Meibohm , Mercedes Gonzalez-Juarrero

Development of a Mucoadhesive Liquid Crystal System for the Administration of Rifampicin Applicable in Tuberculosis Therapy.

Life (Basel, Switzerland)

Avec: Kaio Pini Santos , Camila Fernanda Rodero , Camila Maríngolo Ribeiro , Maria P D Gremião , Rosângela Gonçalves Peccinini , Fernando Rogerio Pavan , Camron Pearce , Mercedes Gonzalez-Juarrero , Marlus Chorilli

Minipigs as a neonatal animal model for tuberculosis vaccine efficacy testing.

Veterinary immunology and immunopathology

Avec: Laylaa Ramos , Andres Obregon-Henao , Marcela Henao-Tamayo , Richard Bowen , Angelo Izzo , Joan K Lunney , Mercedes Gonzalez-Juarrero

A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides.

bioRxiv : the preprint server for biology

Avec: Malik Zohaib Ali , Taru S Dutt , Amy MacNeill , Amanda Walz , Johnathan Patterson , Camron Pearce , Ha Lam , Marcela Henao-Tamayo , Richard E Lee , Jiuyu Liu , Gregory T Robertson , Anthony J Hickey , Bernd Meibohm , Mercedes Gonzalez-Juarrero

Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations.

Tuberculosis (Edinburgh, Scotland)

Avec: Véronique Dartois , Tracey L Bonfield , Jim P Boyce , Charles L Daley , Thomas Dick , Mercedes Gonzalez-Juarrero , Shashank Gupta , Igor Kramnik , Gyanu Lamichhane , Barbara E Laughon , Nicola I Lorè , Kenneth C Malcolm , Kenneth N Olivier , Katherine L Tuggle , Mary Jackson

Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599.

Pharmaceutical research

Avec: Ian E Stewart , Pradeep B Lukka , Jiuyu Liu , Bernd Meibohm , Mercedes Gonzalez-Juarrero , Miriam S Braunstein , Richard E Lee , Anthony J Hickey

Neonatal and infant immunity for tuberculosis vaccine development: importance of age-matched animal models.

Disease models & mechanisms

Avec: Laylaa Ramos , Joan K Lunney , Mercedes Gonzalez-Juarrero

Role of succinyl substituents in the mannose-capping of lipoarabinomannan and control of inflammation in Mycobacterium tuberculosis infection.

PLoS pathogens

Avec: Zuzana Palčeková , Andrés Obregón-Henao , Kavita De , Amanda Walz , Ha Lam , Jamie Philp , Shiva Kumar Angala , Johnathan Patterson , Camron Pearce , Sophie Zuberogoitia , Charlotte Avanzi , Jérôme Nigou , Michael McNeil , Juan F Muñoz Gutiérrez , Martine Gilleron , William H Wheat , Mercedes Gonzalez-Juarrero , Mary Jackson

Intrapulmonary Treatment with Mycobacteriophage LysB Rapidly Reduces Mycobacterium abscessus Burden.

Antimicrobial agents and chemotherapy

Avec: Kelley Hurst-Hess , Amanda Walz , Yong Yang , Helen McGuirk , Mercedes Gonzalez-Juarrero , Graham F Hatfull , Pallavi Ghosh , Anil K Ojha

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.

Antimicrobial agents and chemotherapy

Avec: Allison A Bauman , Jansy P Sarathy , Firat Kaya , Lisa M Massoudi , Michael S Scherman , Courtney Hastings , Jiuyu Liu , Min Xie , Elizabeth J Brooks , Michelle E Ramey , Isabelle L Jones , Noalani D Benedict , Madelyn R Maclaughlin , Jake A Miller-Dawson , Samanthi L Waidyarachchi , Michelle M Butler , Terry L Bowlin , Matthew D Zimmerman , Anne J Lenaerts , Bernd Meibohm , Mercedes Gonzalez-Juarrero , Michael A Lyons , Veronique Dartois , Richard E Lee , Gregory T Robertson

ACS infectious diseases

Avec: Santosh Kumar , Jordan T Koehn , Mercedes Gonzalez-Juarrero , Debbie C Crans , Dean C Crick

Direct Inhibition of MmpL3 by Novel Antitubercular Compounds.

ACS infectious diseases

Avec: Wei Li , Casey M Stevens , Amitkumar N Pandya , Zbigniew Darzynkiewicz , Pankaj Bhattarai , Weiwei Tong , Mercedes Gonzalez-Juarrero , E Jeffrey North , Helen I Zgurskaya , Mary Jackson

Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis.

ACS infectious diseases

Avec: Mercedes Gonzalez-Juarrero , Pradeep B Lukka , Santosh Wagh , Amanda Walz , Jennifer Arab , Camron Pearce , Zohaib Ali , Josiah T Ryman , Keyur Parmar , Zaid Temrikar , Juan Munoz-Gutierrez , Gregory T Robertson , Jiuyu Liu , Anne J Lenaerts , Charles Daley , Richard E Lee , Miriam Braunstein , Anthony J Hickey , Bernd Meibohm

Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication

Precision nanomedicine

Avec: Guankui Wang , Hanmant Gaikwad , Mary K McCarthy , Mercedes Gonzalez-Juarrero , Yue Li , Michael Armstrong , Nichole Reisdorph , Thomas E Morrison , Dmitri Simberg

Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in

Science translational medicine

Avec: Juan Manuel Belardinelli , Deepshikha Verma , Wei Li , Charlotte Avanzi , Crystal J Wiersma , John T Williams , Benjamin K Johnson , Matthew Zimmerman , Nicholas Whittel , Bhanupriya Angala , Han Wang , Victoria Jones , Véronique Dartois , Vinicius C N de Moura , Mercedes Gonzalez-Juarrero , Camron Pearce , Alan R Schenkel , Kenneth C Malcolm , Jerry A Nick , Susan A Charman , Timothy N C Wells , Brendan K Podell , Jonathan L Vennerstrom , Diane J Ordway , Robert B Abramovitch , Mary Jackson

Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics.

Pharmaceutics

Avec: Keyur R Parmar , Pradeep B Lukka , Santosh Wagh , Zaid H Temrikar , Jiuyu Liu , Richard E Lee , Miriam Braunstein , Anthony J Hickey , Gregory T Robertson , Mercedes Gonzalez-Juarrero , Andrea Edginton , Bernd Meibohm

Disposable Dosators Intended for Dry Powder Delivery to Mice.

Journal of visualized experiments : JoVE

Avec: Sara E Maloney , Ian E Stewart , Jeffrey B Mecham , Mercedes Gonzalez-Juarrero , Bernd Meibohm , Anthony J Hickey

Impact of Methylthioxylose Substituents on the Biological Activities of Lipomannan and Lipoarabinomannan in

ACS infectious diseases

Avec: Zuzana Palčeková , Kavita De , Shiva Kumar Angala , Martine Gilleron , Sophie Zuberogoitia , Lucie Gouxette , Maritza Soto-Ojeda , Mercedes Gonzalez-Juarrero , Andrés Obregón-Henao , Jérôme Nigou , William H Wheat , Mary Jackson

Inhaled tigecycline is effective against Mycobacterium abscessus in vitro and in vivo.

The Journal of antimicrobial chemotherapy

Avec: Camron Pearce , Mike M Ruth , Lian J Pennings , Heiman F L Wertheim , Amanda Walz , Wouter Hoefsloot , Carolien Ruesen , Juan Muñoz Gutiérrez , Mercedes Gonzalez-Juarrero , Jakko van Ingen

Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice.

Tuberculosis (Edinburgh, Scotland)

Avec: Chetan Rathi , Pradeep B Lukka , Santosh Wagh , Richard E Lee , Anne J Lenaerts , Miriam Braunstein , Anthony Hickey , Mercedes Gonzalez-Juarrero , Bernd Meibohm

Unique Features of

Frontiers in microbiology

Avec: Juan M Belardinelli , Wei Li , Charlotte Avanzi , Shiva K Angala , Elena Lian , Crystal J Wiersma , Zuzana Palčeková , Kevin H Martin , Bhanupriya Angala , Vinicius C N de Moura , Callan Kerns , Victoria Jones , Mercedes Gonzalez-Juarrero , Rebecca M Davidson , Jerry A Nick , Bradley R Borlee , Mary Jackson

Mycobacterium leprae Infection in a Wild Nine-Banded Armadillo, Nuevo León, Mexico.

Emerging infectious diseases

Avec: Lucio Vera-Cabrera , Cesar J Ramos-Cavazos , Nathan A Youssef , Camron M Pearce , Carmen A Molina-Torres , Ramiro Avalos-Ramirez , Sebastien Gagneux , Jorge Ocampo-Candiani , Mercedes Gonzalez-Juarrero , Jorge A Mayorga-Rodriguez , Leonardo Mayorga-Garibaldi , John S Spencer , Mary Jackson , Charlotte Avanzi

Respirable Clofazimine Particles Produced by Air Jet Milling Technique Are Efficacious in Treatment of BALB/c Mice with Chronic Mycobacterium tuberculosis Infection.

Antimicrobial agents and chemotherapy

Avec: Ashlee D Brunaugh , Amanda Walz , Zachary Warnken , Camron Pearce , Juan Munoz Gutierrez , John J Koleng , Hugh D C Smyth , Mercedes Gonzalez-Juarrero

Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis.

Cell reports

Avec: Taru S Dutt , Burton R Karger , Amy Fox , Nathan Youssef , Rhythm Dadhwal , Malik Zohaib Ali , Johnathan Patterson , Elizabeth Creissen , Elisa Rampacci , Sarah K Cooper , Brendan K Podell , Mercedes Gonzalez-Juarrero , Andres Obregon-Henao , Marcela Henao-Tamayo

Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.

Tuberculosis (Edinburgh, Scotland)

Avec: Urs A Ochsner , Mary A De Groote , Thale C Jarvis , Hang Liu , Tessa Youmans , Teresa Hoang , Wendy Ribble , Joshua Day , Wei Li , Camron Pearce , Amanda Walz , Chandra M Panthi , Binayak Rimal , Casey M Stevens , Helen I Zgurskaya , Mary Jackson , Diane Ordway , Mercedes Gonzalez-Juarrero , Xicheng Sun , Gyanu Lamichhane , Clifford Mason

Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections.

Tuberculosis (Edinburgh, Scotland)

Avec: Sara E Maloney , Ilham M Alshiraihi , Amarinder Singh , Ian E Stewart , Jeffrey Mariner Gonzalez , Mercedes Gonzalez-Juarrero , Bernd Meibohm , Anthony J Hickey

Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes.

Tuberculosis (Edinburgh, Scotland)

Avec: Zaid H Temrikar , Sunitha Kodidela , Santosh Kumar , Jiuyu Liu , Gregory T Robertson , Richard E Lee , Anthony J Hickey , Mercedes Gonzalez-Juarrero , Bernd Meibohm

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.

bioRxiv : the preprint server for biology

Avec: Allison A Bauman , Jansy P Sarathy , Firat Kaya , Lisa M Massoudi , Michael S Scherman , Courtney Hastings , Jiuyu Liu , Min Xie , Elizabeth J Brooks , Michelle E Ramey , Isabelle L Jones , Noalani D Benedict , Madelyn R Maclaughlin , Jake A Miller-Dawson , Samanthi L Waidyarachchi , Michelle M Butler , Terry L Bowlin , Matthew D Zimmerman , Anne J Lenaerts , Bernd Meibohm , Mercedes Gonzalez-Juarrero , Michael A Lyons , Véronique Dartois , Richard E Lee , Gregory T Robertson

Réseau de co-auteurs

Bernd Meibohm 11 collaborations

Camron Pearce 9 collaborations

Amanda Walz 8 collaborations

Anthony J Hickey 8 collaborations

Richard E Lee 8 collaborations

Mary Jackson 8 collaborations

Jiuyu Liu 7 collaborations

Gregory T Robertson 6 collaborations

Pradeep B Lukka 5 collaborations

Miriam Braunstein 4 collaborations

Charlotte Avanzi 4 collaborations

Anne J Lenaerts 4 collaborations

Wei Li 4 collaborations

Marcela Henao-Tamayo 3 collaborations

Johnathan Patterson 3 collaborations

Véronique Dartois 3 collaborations

Ian E Stewart 3 collaborations

Zuzana Palčeková 3 collaborations

Santosh Wagh 3 collaborations

Elizabeth Creissen 2 collaborations

Laylaa Ramos 2 collaborations

Andres Obregon-Henao 2 collaborations

Joan K Lunney 2 collaborations

Malik Zohaib Ali 2 collaborations

Taru S Dutt 2 collaborations

Ha Lam 2 collaborations

Gyanu Lamichhane 2 collaborations

Kenneth C Malcolm 2 collaborations

Andrés Obregón-Henao 2 collaborations

Kavita De 2 collaborations

Shiva Kumar Angala 2 collaborations

Sophie Zuberogoitia 2 collaborations

Jérôme Nigou 2 collaborations

Martine Gilleron 2 collaborations

William H Wheat 2 collaborations

Allison A Bauman 2 collaborations

Jansy P Sarathy 2 collaborations

Firat Kaya 2 collaborations

Lisa M Massoudi 2 collaborations

Michael S Scherman 2 collaborations

Courtney Hastings 2 collaborations

Min Xie 2 collaborations

Elizabeth J Brooks 2 collaborations

Michelle E Ramey 2 collaborations

Isabelle L Jones 2 collaborations

Noalani D Benedict 2 collaborations

Madelyn R Maclaughlin 2 collaborations

Jake A Miller-Dawson 2 collaborations

Samanthi L Waidyarachchi 2 collaborations

Michelle M Butler 2 collaborations

Terry L Bowlin 2 collaborations

Matthew D Zimmerman 2 collaborations

Michael A Lyons 2 collaborations

Santosh Kumar 2 collaborations

Casey M Stevens 2 collaborations

Helen I Zgurskaya 2 collaborations

Crystal J Wiersma 2 collaborations

Bhanupriya Angala 2 collaborations

Victoria Jones 2 collaborations

Vinicius C N de Moura 2 collaborations

Jerry A Nick 2 collaborations

Brendan K Podell 2 collaborations

Zaid H Temrikar 2 collaborations

Sara E Maloney 2 collaborations

Kaio Pini Santos 1 collaboration

Camila Fernanda Rodero 1 collaboration

Camila Maríngolo Ribeiro 1 collaboration

Maria P D Gremião 1 collaboration

Rosângela Gonçalves Peccinini 1 collaboration

Fernando Rogerio Pavan 1 collaboration

Marlus Chorilli 1 collaboration

Richard Bowen 1 collaboration

Angelo Izzo 1 collaboration

Amy MacNeill 1 collaboration

Tracey L Bonfield 1 collaboration

Jim P Boyce 1 collaboration

Charles L Daley 1 collaboration

Thomas Dick 1 collaboration

Shashank Gupta 1 collaboration

Igor Kramnik 1 collaboration

Barbara E Laughon 1 collaboration

Nicola I Lorè 1 collaboration

Kenneth N Olivier 1 collaboration

Katherine L Tuggle 1 collaboration

Miriam S Braunstein 1 collaboration

Jamie Philp 1 collaboration

Michael McNeil 1 collaboration

Juan F Muñoz Gutiérrez 1 collaboration

Kelley Hurst-Hess 1 collaboration

Yong Yang 1 collaboration

Helen McGuirk 1 collaboration

Graham F Hatfull 1 collaboration

Pallavi Ghosh 1 collaboration

Anil K Ojha 1 collaboration

Veronique Dartois 1 collaboration

Jordan T Koehn 1 collaboration

Debbie C Crans 1 collaboration

Dean C Crick 1 collaboration

Amitkumar N Pandya 1 collaboration

Zbigniew Darzynkiewicz 1 collaboration

Pankaj Bhattarai 1 collaboration

Weiwei Tong 1 collaboration

E Jeffrey North 1 collaboration

Jennifer Arab 1 collaboration

Zohaib Ali 1 collaboration

Josiah T Ryman 1 collaboration

Keyur Parmar 1 collaboration

Zaid Temrikar 1 collaboration

Juan Munoz-Gutierrez 1 collaboration

Charles Daley 1 collaboration

Guankui Wang 1 collaboration

Hanmant Gaikwad 1 collaboration

Mary K McCarthy 1 collaboration

Yue Li 1 collaboration

Michael Armstrong 1 collaboration

Nichole Reisdorph 1 collaboration

Thomas E Morrison 1 collaboration

Dmitri Simberg 1 collaboration

Juan Manuel Belardinelli 1 collaboration

Deepshikha Verma 1 collaboration

John T Williams 1 collaboration

Benjamin K Johnson 1 collaboration

Matthew Zimmerman 1 collaboration

Nicholas Whittel 1 collaboration

Han Wang 1 collaboration

Alan R Schenkel 1 collaboration

Susan A Charman 1 collaboration

Timothy N C Wells 1 collaboration

Jonathan L Vennerstrom 1 collaboration

Diane J Ordway 1 collaboration

Robert B Abramovitch 1 collaboration

Keyur R Parmar 1 collaboration

Andrea Edginton 1 collaboration

Jeffrey B Mecham 1 collaboration

Lucie Gouxette 1 collaboration

Maritza Soto-Ojeda 1 collaboration

Mike M Ruth 1 collaboration

Lian J Pennings 1 collaboration

Heiman F L Wertheim 1 collaboration

Wouter Hoefsloot 1 collaboration

Carolien Ruesen 1 collaboration

Juan Muñoz Gutiérrez 1 collaboration

Jakko van Ingen 1 collaboration

Chetan Rathi 1 collaboration

Anthony Hickey 1 collaboration

Juan M Belardinelli 1 collaboration

Shiva K Angala 1 collaboration

Elena Lian 1 collaboration

Kevin H Martin 1 collaboration

Callan Kerns 1 collaboration

Rebecca M Davidson 1 collaboration

Bradley R Borlee 1 collaboration

Lucio Vera-Cabrera 1 collaboration

Cesar J Ramos-Cavazos 1 collaboration

Nathan A Youssef 1 collaboration

Camron M Pearce 1 collaboration

Carmen A Molina-Torres 1 collaboration

Ramiro Avalos-Ramirez 1 collaboration

Sebastien Gagneux 1 collaboration

Jorge Ocampo-Candiani 1 collaboration

Jorge A Mayorga-Rodriguez 1 collaboration

Leonardo Mayorga-Garibaldi 1 collaboration

John S Spencer 1 collaboration

Ashlee D Brunaugh 1 collaboration

Zachary Warnken 1 collaboration

Juan Munoz Gutierrez 1 collaboration

John J Koleng 1 collaboration

Hugh D C Smyth 1 collaboration

Burton R Karger 1 collaboration

Amy Fox 1 collaboration

Nathan Youssef 1 collaboration

Rhythm Dadhwal 1 collaboration

Elisa Rampacci 1 collaboration

Sarah K Cooper 1 collaboration

Urs A Ochsner 1 collaboration

Mary A De Groote 1 collaboration

Thale C Jarvis 1 collaboration

Hang Liu 1 collaboration

Tessa Youmans 1 collaboration

Teresa Hoang 1 collaboration

Wendy Ribble 1 collaboration

Joshua Day 1 collaboration

Chandra M Panthi 1 collaboration

Binayak Rimal 1 collaboration

Diane Ordway 1 collaboration

Xicheng Sun 1 collaboration

Clifford Mason 1 collaboration

Ilham M Alshiraihi 1 collaboration

Amarinder Singh 1 collaboration

Jeffrey Mariner Gonzalez 1 collaboration

Sunitha Kodidela 1 collaboration