Matthias Hardtke-Wolenski

Affiliations

Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany, HepNet Study-House, German Liver Foundation, Hannover, Germany.

Publications (19)

Long-Lasting Imprint in the Soluble Inflammatory Milieu Despite Early Treatment of Acute Symptomatic Hepatitis C.

The Journal of infectious diseases

Avec: Tanvi Khera , Yanqin Du , Daniel Todt , Katja Deterding , Benedikt Strunz , Svenja Hardtke , Amare Aregay , Kerstin Port , Matthias Hardtke-Wolenski , Eike Steinmann , Niklas K Björkström , Michael P Manns , Julia Hengst , Markus Cornberg , Heiner Wedemeyer

The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis.

Hepatology communications

Avec: Janine Dywicki , Laura Elisa Buitrago-Molina , Fatih Noyan , Ana C Davalos-Misslitz , Katharina L Hupa-Breier , Maren Lieber , Martin Hapke , Jerome Schlue , Christine S Falk , Solaiman Raha , Immo Prinz , Christian Koenecke , Michael P Manns , Heiner Wedemeyer , Matthias Hardtke-Wolenski , Elmar Jaeckel

Membrane-bound IL-2 improves the expansion, survival, and phenotype of CAR Tregs and confers resistance to calcineurin inhibitors.

Frontiers in immunology

Avec: Jakob Kremer , Pierre Henschel , Daniel Simon , Tobias Riet , Christine Falk , Matthias Hardtke-Wolenski , Heiner Wedemeyer , Fatih Noyan , Elmar Jaeckel

Generation of Chimeric Antigen Receptors against Tetraspanin 7.

Cells

Avec: Tom Pieper , Kristian Daniel Ralph Roth , Viktor Glaser , Tobias Riet , Laura Elisa Buitrago-Molina , Maike Hagedorn , Maren Lieber , Michael Hust , Fatih Noyan , Elmar Jaeckel , Matthias Hardtke-Wolenski

Dulaglutide Alone and in Combination with Empagliflozin Attenuate Inflammatory Pathways and Microbiome Dysbiosis in a Non-Diabetic Mouse Model of NASH.

Biomedicines

Avec: Katharina Luise Hupa-Breier , Janine Dywicki , Björn Hartleben , Freya Wellhöner , Benjamin Heidrich , Richard Taubert , Young-Seon Elisabeth Mederacke , Maren Lieber , Konstantinos Iordanidis , Michael P Manns , Heiner Wedemeyer , Matthias Hardtke-Wolenski , Elmar Jaeckel

9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes.

International journal of molecular sciences

Avec: Adriana R Schultz Moreira , Sabrina Rüschenbaum , Stefan Schefczyk , Ulrike Hendgen-Cotta , Tienush Rassaf , Ruth Broering , Matthias Hardtke-Wolenski , Laura Elisa Buitrago-Molina

Development of Beta-Amyloid-Specific CAR-Tregs for the Treatment of Alzheimer's Disease.

Cells

Avec: Valerie Saetzler , Tobias Riet , Andrea Schienke , Pierre Henschel , Kiara Freitag , Alexander Haake , Frank L Heppner , Laura Elisa Buitrago-Molina , Fatih Noyan , Elmar Jaeckel , Matthias Hardtke-Wolenski

Splenectomy Prior to Experimental Induction of Autoimmune Hepatitis Promotes More Severe Hepatic Inflammation, Production of IL-17 and Apoptosis.

Biomedicines

Avec: Laura Elisa Buitrago-Molina , Janine Dywicki , Fatih Noyan , Martin Trippler , Julia Pietrek , Jerome Schlue , Michael P Manns , Heiner Wedemeyer , Elmar Jaeckel , Matthias Hardtke-Wolenski

Anti-CD20 Therapy Alters the Protein Signature in Experimental Murine AIH, but Not Exclusively towards Regeneration.

Cells

Avec: Laura Elisa Buitrago-Molina , Janine Dywicki , Fatih Noyan , Lena Schepergerdes , Julia Pietrek , Maren Lieber , Jerome Schlue , Michael P Manns , Heiner Wedemeyer , Elmar Jaeckel , Matthias Hardtke-Wolenski

PD-1/CTLA-4 Blockade Leads to Expansion of CD8

Liver cancer

Avec: Sandra Bufe , Artur Zimmermann , Sarina Ravens , Immo Prinz , Laura Elisa Buitrago-Molina , Robert Geffers , Norman Woller , Florian Kühnel , Steven R Talbot , Fatih Noyan , Michael Peter Manns , Heiner Wedemeyer , Matthias Hardtke-Wolenski , Elmar Jaeckel , Ana C Davalos-Misslitz

Tipping the balance in autoimmunity: are regulatory t cells the cause, the cure, or both?

Molecular and cellular pediatrics

Avec: Matthias Hardtke-Wolenski , Sybille Landwehr-Kenzel

Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction.

Cells

Avec: Nadja Seltrecht , Matthias Hardtke-Wolenski , Konstantinos Iordanidis , Danny Jonigk , Melanie Galla , Axel Schambach , Laura Elisa Buitrago-Molina , Heiner Wedemeyer , Fatih Noyan , Elmar Jaeckel

Regulatory T cells engineered with a novel insulin-specific chimeric antigen receptor as a candidate immunotherapy for type 1 diabetes.

Journal of autoimmunity

Avec: Michel Tenspolde , Katharina Zimmermann , Leonie C Weber , Martin Hapke , Maren Lieber , Janine Dywicki , Andre Frenzel , Michael Hust , Melanie Galla , Laura E Buitrago-Molina , Michael P Manns , Elmar Jaeckel , Matthias Hardtke-Wolenski

Autoimmune hepatitis induction can occur in the liver.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Janine Dywicki , Laura Elisa Buitrago-Molina , Julia Pietrek , Maren Lieber , Ruth Broering , Tanvi Khera , Jerome Schlue , Michael P Manns , Heiner Wedemeyer , Elmar Jaeckel , Matthias Hardtke-Wolenski

Treg-specific IL-2 therapy can reestablish intrahepatic immune regulation in autoimmune hepatitis.

Journal of autoimmunity

Avec: Laura Elisa Buitrago-Molina , Julia Pietrek , Fatih Noyan , Jerome Schlue , Michael P Manns , Heiner Wedemeyer , Matthias Hardtke-Wolenski , Elmar Jaeckel

Absence of Atg7 in the liver disturbed hepatic regeneration after liver injury.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Dorothee Römermann , Nadiea Ansari , Adriana Rita Schultz-Moreira , Alina Michael , Silke Marhenke , Matthias Hardtke-Wolenski , Thomas Longerich , Michael P Manns , Heiner Wedemeyer , Arndt Vogel , Laura Elisa Buitrago-Molina

The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B virus infection.

Liver international : official journal of the International Association for the Study of the Liver

Avec: Yanqin Du , Olympia E Anastasiou , Benedikt Strunz , Janina Scheuten , Birgit Bremer , Anke Kraft , Karolina Kleinsimglinhaus , Daniel Todt , Ruth Broering , Matthias Hardtke-Wolenski , Jun Wu , Dongliang Yang , Ulf Dittmer , Mengji Lu , Markus Cornberg , Niklas K Björkström , Tanvi Khera , Heiner Wedemeyer

Splenectomy induces biochemical remission and regeneration in experimental murine autoimmune hepatitis.

European journal of medical research

Avec: Janine Dywicki , Laura Elisa Buitrago-Molina , Fatih Noyan , Jerome Schlue , Konstantinos Iordanidis , Michael P Manns , Heiner Wedemeyer , Elmar Jaeckel , Matthias Hardtke-Wolenski

Supraphysiological FOXP3 expression in human CAR-Tregs results in improved stability, efficacy, and safety of CAR-Treg products for clinical application.

Journal of autoimmunity

Avec: Pierre Henschel , Sybille Landwehr-Kenzel , Niklas Engels , Andrea Schienke , Jakob Kremer , Tobias Riet , Nella Redel , Konstantinos Iordanidis , Valerie Saetzler , Katharina John , Miriam Heider , Matthias Hardtke-Wolenski , Heiner Wedemeyer , Elmar Jaeckel , Fatih Noyan

Réseau de co-auteurs

Heiner Wedemeyer 14 collaborations

Elmar Jaeckel 14 collaborations

Laura Elisa Buitrago-Molina 12 collaborations

Fatih Noyan 11 collaborations

Michael P Manns 10 collaborations

Janine Dywicki 7 collaborations

Maren Lieber 6 collaborations

Jerome Schlue 6 collaborations

Tobias Riet 4 collaborations

Konstantinos Iordanidis 4 collaborations

Julia Pietrek 4 collaborations

Tanvi Khera 3 collaborations

Pierre Henschel 3 collaborations

Ruth Broering 3 collaborations

Yanqin Du 2 collaborations

Daniel Todt 2 collaborations

Benedikt Strunz 2 collaborations

Niklas K Björkström 2 collaborations

Markus Cornberg 2 collaborations

Ana C Davalos-Misslitz 2 collaborations

Martin Hapke 2 collaborations

Immo Prinz 2 collaborations

Jakob Kremer 2 collaborations

Michael Hust 2 collaborations

Valerie Saetzler 2 collaborations

Andrea Schienke 2 collaborations

Sybille Landwehr-Kenzel 2 collaborations

Melanie Galla 2 collaborations

Katja Deterding 1 collaboration

Svenja Hardtke 1 collaboration

Amare Aregay 1 collaboration

Kerstin Port 1 collaboration

Eike Steinmann 1 collaboration

Julia Hengst 1 collaboration

Katharina L Hupa-Breier 1 collaboration

Christine S Falk 1 collaboration

Solaiman Raha 1 collaboration

Christian Koenecke 1 collaboration

Daniel Simon 1 collaboration

Christine Falk 1 collaboration

Tom Pieper 1 collaboration

Kristian Daniel Ralph Roth 1 collaboration

Viktor Glaser 1 collaboration

Maike Hagedorn 1 collaboration

Katharina Luise Hupa-Breier 1 collaboration

Björn Hartleben 1 collaboration

Freya Wellhöner 1 collaboration

Benjamin Heidrich 1 collaboration

Richard Taubert 1 collaboration

Young-Seon Elisabeth Mederacke 1 collaboration

Adriana R Schultz Moreira 1 collaboration

Sabrina Rüschenbaum 1 collaboration

Stefan Schefczyk 1 collaboration

Ulrike Hendgen-Cotta 1 collaboration

Tienush Rassaf 1 collaboration

Kiara Freitag 1 collaboration

Alexander Haake 1 collaboration

Frank L Heppner 1 collaboration

Martin Trippler 1 collaboration

Lena Schepergerdes 1 collaboration

Sandra Bufe 1 collaboration

Artur Zimmermann 1 collaboration

Sarina Ravens 1 collaboration

Robert Geffers 1 collaboration

Norman Woller 1 collaboration

Florian Kühnel 1 collaboration

Steven R Talbot 1 collaboration

Michael Peter Manns 1 collaboration

Nadja Seltrecht 1 collaboration

Danny Jonigk 1 collaboration

Axel Schambach 1 collaboration

Michel Tenspolde 1 collaboration

Katharina Zimmermann 1 collaboration

Leonie C Weber 1 collaboration

Andre Frenzel 1 collaboration

Laura E Buitrago-Molina 1 collaboration

Dorothee Römermann 1 collaboration

Nadiea Ansari 1 collaboration

Adriana Rita Schultz-Moreira 1 collaboration

Alina Michael 1 collaboration

Silke Marhenke 1 collaboration

Thomas Longerich 1 collaboration

Arndt Vogel 1 collaboration

Olympia E Anastasiou 1 collaboration

Janina Scheuten 1 collaboration

Birgit Bremer 1 collaboration

Anke Kraft 1 collaboration

Karolina Kleinsimglinhaus 1 collaboration

Jun Wu 1 collaboration

Dongliang Yang 1 collaboration

Ulf Dittmer 1 collaboration

Mengji Lu 1 collaboration

Niklas Engels 1 collaboration

Nella Redel 1 collaboration

Katharina John 1 collaboration

Miriam Heider 1 collaboration