Mary Kay H Pflum

Affiliations

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.

ORCID: 0000-0002-1396-3194

Publications (22)

Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling.

Journal of proteome research

Avec: Vindya Ramanayake-Mudiyanselage , D Maheeka Embogama , Mary Kay H Pflum

Valproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase.

Scientific reports

Avec: Kendall C Case , Rachel J Beltman , Mary Kay H Pflum , Miriam L Greenberg

Kinase-Catalyzed Biotinylation to Identify Phosphatase Substrates (K-BIPS).

Methods in molecular biology (Clifton, N.J.)

Avec: Hannah J Bremer , Mary Kay H Pflum

EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function.

Cell death & disease

Avec: Sonali Bahl , Hongbo Ling , Nuwan P N Acharige , Irene Santos-Barriopedro , Mary Kay H Pflum , Edward Seto

An Affinity-Based, Cysteine-Specific ATP Analog for Kinase-Catalyzed Crosslinking.

Angewandte Chemie (International ed. in English)

Avec: Ahmed E Fouda , Aparni K Gamage , Mary Kay H Pflum

Identification of PP1c-PPP1R12A Substrates Using Kinase-Catalyzed Biotinylation to Identify Phosphatase Substrates.

ACS omega

Avec: Pavithra M Dedigama-Arachchige , Nuwan P N Acharige , Xiangmin Zhang , Hannah J Bremer , Zhengping Yi , Mary Kay H Pflum

A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.

Bioorganic chemistry

Avec: Ayad A Al-Hamashi , Radhika Koranne , Samkeliso Dlamini , Abdulateef Alqahtani , Endri Karaj , Maisha S Rashid , Joseph R Knoff , Matthew Dunworth , Mary Kay H Pflum , Robert A Casero , Lalith Perera , William R Taylor , L M Viranga Tillekeratne

HDAC6 Substrate Discovery Using Proteomics-Based Substrate Trapping: HDAC6 Deacetylates PRMT5 to Influence Methyltransferase Activity.

ACS chemical biology

Avec: Inosha D Gomes , Udana V Ariyaratne , Mary Kay H Pflum

Protein kinase A is a functional component of focal adhesions.

The Journal of biological chemistry

Avec: Mingu Kang , Amanda J Senatore , Hannah Naughton , Madeline McTigue , Rachel J Beltman , Andrew A Herppich , Mary Kay H Pflum , Alan K Howe

Kinase-catalyzed Biotinylation with Inactivated Lysates for Discovery of Substrates (K-BILDS).

Current protocols

Avec: Chelsea R Gary , Mary Kay H Pflum

Kinase-catalyzed crosslinking: A comparison of ATP-crosslinker analogs.

Bioorganic & medicinal chemistry letters

Avec: Hannah J Bremer , Andrew A Herppich , Mary Kay H Pflum

Optimal Substrate-Trapping Mutants to Discover Substrates of HDAC1.

Chembiochem : a European journal of chemical biology

Avec: Inosha D Gomes , Mary Kay H Pflum

Kinase-Catalyzed Crosslinking and Immunoprecipitation (K-CLIP) to Explore Kinase-Substrate Pairs.

Current protocols

Avec: Rachel J Beltman , Mary Kay H Pflum

Kinase-catalyzed Biotinylation for Discovery and Validation of Substrates to Multi-specificity Kinases NME1 and NME2.

The Journal of biological chemistry

Avec: Chelsea R Gary , Nuwan P N Acharige , Tolulope O Oyewumi , Mary Kay H Pflum

l-Lactate Dehydrogenase Identified as a Protein Tyrosine Phosphatase 1B Substrate by Using K-BIPS.

Chembiochem : a European journal of chemical biology

Avec: Nuwan P N Acharige , Mary Kay H Pflum

Differential profiles of HDAC1 substrates and associated proteins in breast cancer cells revealed by trapping.

Molecular omics

Avec: Yuchen Zhang , Dhanusha A Nalawansha , Kavinda E Herath , Rafael Andrade , Mary Kay H Pflum

Evidence that HDAC7 acts as an epigenetic "reader" of AR acetylation through NCoR-HDAC3 dissociation.

Cell chemical biology

Avec: Yuchen Zhang , Rafael Andrade , Anthony A Hanna , Mary Kay H Pflum

Phosphorylation of cell cycle and apoptosis regulatory protein-1 by stress activated protein kinase P38γ is a novel mechanism of apoptosis signaling by genotoxic chemotherapy.

Frontiers in oncology

Avec: Jaganathan Venkatesh , Magesh Muthu , Indulekha Singaravelu , Vino T Cheriyan , Sreeja C Sekhar , Nuwan C P N Acharige , Edi Levi , Hadeel Assad , Mary Kay H Pflum , Arun K Rishi

Proteomics-based trapping with single or multiple inactive mutants reproducibly profiles histone deacetylase 1 substrates.

Journal of proteomics

Avec: Kavinda E Herath , Ishadi K M Kodikara , Mary Kay H Pflum

Protein Kinase A is a Functional Component of Focal Adhesions.

bioRxiv : the preprint server for biology

Avec: Mingu Kang , Amanda J Senatore , Hannah Naughton , Madeline McTigue , Rachel J Beltman , Andrew A Herppich , Mary Kay H Pflum , Alan K Howe

Affinity-Based Kinase-Catalyzed Crosslinking to Study Kinase-Substrate Pairs.

Bioconjugate chemistry

Avec: Rachel J Beltman , Andrew A Herppich , Hannah J Bremer , Mary Kay H Pflum

New Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art.

Journal of the American Society for Mass Spectrometry

Avec: Sarah Trimpin , Frank S Yenchick , Chuping Lee , Khoa Hoang , Milan Pophristic , Santosh Karki , Darrell D Marshall , I-Chung Lu , Corinne A Lutomski , Tarick J El-Baba , Beixi Wang , Vincent S Pagnotti , Anil K Meher , Shubhashis Chakrabarty , Lorelei F Imperial , Sara Madarshahian , Alicia L Richards , Christopher B Lietz , Abigail Moreno-Pedraza , Samantha M Leach , Stephen C Gibson , Efstathios A Elia , Shameemah M Thawoos , Daniel W Woodall , Dean R Jarois , Eric T J Davis , Guochao Liao , Nisansala S Muthunayake , McKenna J Redding , Christian A Reynolds , Thilani M Anthony , Sashiprabha M Vithanarachchi , Paul DeMent , Adeleye O Adewale , Lu Yan , James Wager-Miller , Young-Hoon Ahn , Thomas H Sanderson , Karin Przyklenk , Miriam L Greenberg , Arthur G Suits , Matthew J Allen , Srinivas B Narayan , Joseph A Caruso , Paul M Stemmer , Hien M Nguyen , Steffen M Weidner , Kevin J Rackers , Ana Djuric , Vladimir Shulaev , Tamara L Hendrickson , Christine S Chow , Mary Kay H Pflum , Scott M Grayson , Vladislav V Lobodin , Zhongwu Guo , Chi-Kung Ni , J Michael Walker , Ken Mackie , Ellen D Inutan , Charles N McEwen

Réseau de co-auteurs

Rachel J Beltman 5 collaborations

Hannah J Bremer 4 collaborations

Nuwan P N Acharige 4 collaborations

Andrew A Herppich 4 collaborations

Miriam L Greenberg 2 collaborations

Inosha D Gomes 2 collaborations

Mingu Kang 2 collaborations

Amanda J Senatore 2 collaborations

Hannah Naughton 2 collaborations

Madeline McTigue 2 collaborations

Alan K Howe 2 collaborations

Chelsea R Gary 2 collaborations

Yuchen Zhang 2 collaborations

Kavinda E Herath 2 collaborations

Rafael Andrade 2 collaborations

Vindya Ramanayake-Mudiyanselage 1 collaboration

D Maheeka Embogama 1 collaboration

Kendall C Case 1 collaboration

Sonali Bahl 1 collaboration

Hongbo Ling 1 collaboration

Irene Santos-Barriopedro 1 collaboration

Edward Seto 1 collaboration

Ahmed E Fouda 1 collaboration

Aparni K Gamage 1 collaboration

Pavithra M Dedigama-Arachchige 1 collaboration

Xiangmin Zhang 1 collaboration

Zhengping Yi 1 collaboration

Ayad A Al-Hamashi 1 collaboration

Radhika Koranne 1 collaboration

Samkeliso Dlamini 1 collaboration

Abdulateef Alqahtani 1 collaboration

Endri Karaj 1 collaboration

Maisha S Rashid 1 collaboration

Joseph R Knoff 1 collaboration

Matthew Dunworth 1 collaboration

Robert A Casero 1 collaboration

Lalith Perera 1 collaboration

William R Taylor 1 collaboration

L M Viranga Tillekeratne 1 collaboration

Udana V Ariyaratne 1 collaboration

Tolulope O Oyewumi 1 collaboration

Dhanusha A Nalawansha 1 collaboration

Anthony A Hanna 1 collaboration

Jaganathan Venkatesh 1 collaboration

Magesh Muthu 1 collaboration

Indulekha Singaravelu 1 collaboration

Vino T Cheriyan 1 collaboration

Sreeja C Sekhar 1 collaboration

Nuwan C P N Acharige 1 collaboration

Edi Levi 1 collaboration

Hadeel Assad 1 collaboration

Arun K Rishi 1 collaboration

Ishadi K M Kodikara 1 collaboration

Sarah Trimpin 1 collaboration

Frank S Yenchick 1 collaboration

Chuping Lee 1 collaboration

Khoa Hoang 1 collaboration

Milan Pophristic 1 collaboration

Santosh Karki 1 collaboration

Darrell D Marshall 1 collaboration

I-Chung Lu 1 collaboration

Corinne A Lutomski 1 collaboration

Tarick J El-Baba 1 collaboration

Beixi Wang 1 collaboration

Vincent S Pagnotti 1 collaboration

Anil K Meher 1 collaboration

Shubhashis Chakrabarty 1 collaboration

Lorelei F Imperial 1 collaboration

Sara Madarshahian 1 collaboration

Alicia L Richards 1 collaboration

Christopher B Lietz 1 collaboration

Abigail Moreno-Pedraza 1 collaboration

Samantha M Leach 1 collaboration

Stephen C Gibson 1 collaboration

Efstathios A Elia 1 collaboration

Shameemah M Thawoos 1 collaboration

Daniel W Woodall 1 collaboration

Dean R Jarois 1 collaboration

Eric T J Davis 1 collaboration

Guochao Liao 1 collaboration

Nisansala S Muthunayake 1 collaboration

McKenna J Redding 1 collaboration

Christian A Reynolds 1 collaboration

Thilani M Anthony 1 collaboration

Sashiprabha M Vithanarachchi 1 collaboration

Paul DeMent 1 collaboration

Adeleye O Adewale 1 collaboration

Lu Yan 1 collaboration

James Wager-Miller 1 collaboration

Young-Hoon Ahn 1 collaboration

Thomas H Sanderson 1 collaboration

Karin Przyklenk 1 collaboration

Arthur G Suits 1 collaboration

Matthew J Allen 1 collaboration

Srinivas B Narayan 1 collaboration

Joseph A Caruso 1 collaboration

Paul M Stemmer 1 collaboration

Hien M Nguyen 1 collaboration

Steffen M Weidner 1 collaboration

Kevin J Rackers 1 collaboration

Ana Djuric 1 collaboration

Vladimir Shulaev 1 collaboration

Tamara L Hendrickson 1 collaboration

Christine S Chow 1 collaboration

Scott M Grayson 1 collaboration

Vladislav V Lobodin 1 collaboration

Zhongwu Guo 1 collaboration

Chi-Kung Ni 1 collaboration

J Michael Walker 1 collaboration

Ken Mackie 1 collaboration

Ellen D Inutan 1 collaboration

Charles N McEwen 1 collaboration