Marlene Rabinovitch

Affiliations

Department of Pediatrics, Vera Moulton Wall Center for Pulmonary Vascular Disease and the Cardiovascular Institute, Stanford School of Medicine, Stanford, CA 94305, USA.

Publications (24)

Cellular senescence impairs the reversibility of pulmonary arterial hypertension.

Science translational medicine

Avec: Diederik E van der Feen , Guido P L Bossers , Quint A J Hagdorn , Jan-Renier Moonen , Kondababu Kurakula , Robert Szulcek , James Chappell , Francesco Vallania , Michele Donato , Klaas Kok , Jaskaren S Kohli , Arjen H Petersen , Tom van Leusden , Marco Demaria , Marie-José T H Goumans , Rudolf A De Boer , Purvesh Khatri , Marlene Rabinovitch , Rolf M F Berger , Beatrijs Bartelds

Role of endothelial cells in pulmonary fibrosis via SREBP2 activation.

JCI insight

Avec: Marcy Martin , Jiao Zhang , Yifei Miao , Ming He , Jian Kang , Hsi-Yuan Huang , Chih-Hung Chou , Tse-Shun Huang , Hsiao-Chin Hong , Shu-Han Su , Simon S Wong , Rebecca L Harper , Lingli Wang , Rakesh Bhattacharjee , Hsien-Da Huang , Zhen Bouman Chen , Atul Malhotra , Marlene Rabinovitch , James S Hagood , John Y-J Shyy

Targeted proteomics of right heart adaptation to pulmonary arterial hypertension.

The European respiratory journal

Avec: Myriam Amsallem , Andrew J Sweatt , Jennifer Arthur Ataam , Julien Guihaire , Florence Lecerf , Mélanie Lambert , Maria Rosa Ghigna , Md Khadem Ali , Yuqiang Mao , Elie Fadel , Marlene Rabinovitch , Vinicio de Jesus Perez , Edda Spiekerkoetter , Olaf Mercier , Francois Haddad , Roham T Zamanian

iPSC-endothelial cell phenotypic drug screening and in silico analyses identify tyrphostin-AG1296 for pulmonary arterial hypertension.

Science translational medicine

Avec: Mingxia Gu , Michele Donato , Minzhe Guo , Neil Wary , Yifei Miao , Shuai Mao , Toshie Saito , Shoichiro Otsuki , Lingli Wang , Rebecca L Harper , Silin Sa , Purvesh Khatri , Marlene Rabinovitch

Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.

Chest

Avec: Andrew J Sweatt , Kazuya Miyagawa , Christopher J Rhodes , Shalina Taylor , Patricia A Del Rosario , Andrew Hsi , Francois Haddad , Edda Spiekerkoetter , Michal Bental-Roof , Richard D Bland , Emilia M Swietlik , Stefan Gräf , Martin R Wilkins , Nicholas W Morrell , Mark R Nicolls , Marlene Rabinovitch , Roham T Zamanian

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension.

bioRxiv : the preprint server for biology

Avec: Tsutomu Shinohara , Jan-Renier Moonen , Yoon Hong Chun , Yannick C Lee-Yow , Kenichi Okamura , Jason M Szafron , Jordan Kaplan , Aiqin Cao , Lingli Wang , Shalina Taylor , Sarasa Isobe , Melody Dong , Weiguang Yang , Katherine Guo , Benjamin D Franco , Cholawat Pacharinsak , Laura J Pisani , Shinji Saitoh , Yoshihide Mitani , Alison L Marsden , Jesse M Engreitz , Jakob Körbelin , Marlene Rabinovitch

Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function.

Vascular pharmacology

Avec: Miranda K Culley , Rashmi J Rao , Monica Mehta , Jingsi Zhao , Wadih El Khoury , Lloyd D Harvey , Dror Perk , Yi Yin Tai , Ying Tang , Sruti Shiva , Marlene Rabinovitch , Mingxia Gu , Thomas Bertero , Stephen Y Chan

Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension.

Nature communications

Avec: Armando Reyes-Palomares , Mingxia Gu , Fabian Grubert , Ivan Berest , Silin Sa , Maya Kasowski , Christian Arnold , Mao Shuai , Rohith Srivas , Simon Miao , Dan Li , Michael P Snyder , Marlene Rabinovitch , Judith B Zaugg

Image-based scaling laws for somatic growth and pulmonary artery morphometry from infancy to adulthood.

American journal of physiology. Heart and circulatory physiology

Avec: Melody Dong , Weiguang Yang , John S Tamaresis , Frandics P Chan , Evan J Zucker , Sahana Kumar , Marlene Rabinovitch , Alison L Marsden , Jeffrey A Feinstein

Dual Host-Intracellular Parasite Transcriptome of Enucleated Cells Hosting

Infection and immunity

Avec: Cristina M Orikaza , Carina C Pessoa , Fernanda V Paladino , Pilar T V Florentino , Clara L Barbiéri , Hiro Goto , Eduardo Milton Ramos-Sanchez , José Franco da Silveira , Michel Rabinovitch , Renato A Mortara , Fernando Real

Proceedings From the 2019 Stanford Single Ventricle Scientific Summit: Advancing Science for Single Ventricle Patients: From Discovery to Clinical Applications.

Journal of the American Heart Association

Avec: Sushma Reddy , Stephanie Siehr Handler , Sean Wu , Marlene Rabinovitch , Gail Wright

Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure.

Pulmonary circulation

Avec: Edda Spiekerkoetter , Elena A Goncharova , Christophe Guignabert , Kurt Stenmark , Grazyna Kwapiszewska , Marlene Rabinovitch , Norbert Voelkel , Harm J Bogaard , Brian Graham , Soni S Pullamsetti , Wolfgang M Kuebler

Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition.

JCI insight

Avec: Shoichiro Otsuki , Toshie Saito , Shalina Taylor , Dan Li , Jan-Renier Moonen , David P Marciano , Rebecca L Harper , Aiqin Cao , Lingli Wang , Maria E Ariza , Marlene Rabinovitch

Measurement Based Care in a first episode psychosis program: Development of an algorithm of care based on the Clinical Global Impressions Scale.

Journal of psychiatric research

Avec: Michelle Khau , Karim Tabbane , David Bloom , Sherezad Abadi , Celine Villemus , Mark Rabinovitch , Jai L Shah , Alexandre Veillette , Srividya N Iyer , Patricia Boksa , Ridha Joober

Respiratory viruses and postoperative hemodynamics in patients with unrestrictive congenital cardiac communications: a prospective cohort study.

European journal of medical research

Avec: Kelly C O Abud , Clarisse M Machado , Lucy S Vilas Boas , Nair Y Maeda , Eloisa S Carvalho , Maria Francilene S Souza , Paula V Gaiolla , Claudia R P Castro , Juliana Pereira , Marlene Rabinovitch , Antonio Augusto Lopes

Pragmatic implementation of the Clinical Global Impression Scale of Severity as a tool for measurement-based care in a first-episode psychosis program.

Schizophrenia research

Avec: Michelle Khau , Karim Tabbane , David Bloom , Sherezad Abadi , Celine Villemus , Mark Rabinovitch , Jai L Shah , Alexandre Veillette , Srividya N Iyer , Patricia Boksa , Ridha Joober

KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress.

Nature communications

Avec: Jan-Renier Moonen , James Chappell , Minyi Shi , Tsutomu Shinohara , Dan Li , Maxwell R Mumbach , Fan Zhang , Ramesh V Nair , Joseph Nasser , Daniel H Mai , Shalina Taylor , Lingli Wang , Ross J Metzger , Howard Y Chang , Jesse M Engreitz , Michael P Snyder , Marlene Rabinovitch

Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.

Circulation research

Avec: Lingli Wang , Jan-Renier Moonen , Aiqin Cao , Sarasa Isobe , Caiyun G Li , Nancy F Tojais , Shalina Taylor , David P Marciano , Pin-I Chen , Mingxia Gu , Dan Li , Rebecca L Harper , Nesrine El-Bizri , Yu-Mee Kim , Kryn Stankunas , Marlene Rabinovitch

A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics.

bioRxiv : the preprint server for biology

Avec: Jason M Szafron , Weiguang Yang , Jeffrey A Feinstein , Marlene Rabinovitch , Alison L Marsden

Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension.

Circulation research

Avec: Andrew J Sweatt , Haley K Hedlin , Vidhya Balasubramanian , Andrew Hsi , Lisa K Blum , William H Robinson , Francois Haddad , Peter M Hickey , Robin Condliffe , Allan Lawrie , Mark R Nicolls , Marlene Rabinovitch , Purvesh Khatri , Roham T Zamanian

Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation.

Circulation

Avec: Wen Tian , Xinguo Jiang , Yon K Sung , Eric Shuffle , Ting-Hsuan Wu , Peter N Kao , Allen B Tu , Peter Dorfmüller , Aiqin Cao , Lingli Wang , Gongyong Peng , Yesl Kim , Patrick Zhang , James Chappell , Shravani Pasupneti , Petra Dahms , Peter Maguire , Hassan Chaib , Roham Zamanian , Marc Peters-Golden , Michael P Snyder , Norbert F Voelkel , Marc Humbert , Marlene Rabinovitch , Mark R Nicolls

Evolution of hemodynamic forces in the pulmonary tree with progressively worsening pulmonary arterial hypertension in pediatric patients.

Biomechanics and modeling in mechanobiology

Avec: Weiguang Yang , Melody Dong , Marlene Rabinovitch , Frandics P Chan , Alison L Marsden , Jeffrey A Feinstein

Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1-Mediated Metabolic and Epigenetic Changes.

Circulation research

Avec: Kazuya Miyagawa , Minyi Shi , Pin-I Chen , Jan K Hennigs , Zhixin Zhao , Mouer Wang , Caiyun G Li , Toshie Saito , Shalina Taylor , Silin Sa , Aiqin Cao , Lingli Wang , Michael P Snyder , Marlene Rabinovitch

ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension.

Circulation

Avec: Dan Li , Ning-Yi Shao , Jan-Renier Moonen , Zhixin Zhao , Minyi Shi , Shoichiro Otsuki , Lingli Wang , Tiffany Nguyen , Elaine Yan , David P Marciano , Kévin Contrepois , Caiyun G Li , Joseph C Wu , Michael P Snyder , Marlene Rabinovitch

Réseau de co-auteurs

Lingli Wang 9 collaborations

Jan-Renier Moonen 6 collaborations

Shalina Taylor 6 collaborations

Aiqin Cao 5 collaborations

Dan Li 5 collaborations

Michael P Snyder 5 collaborations

Rebecca L Harper 4 collaborations

Mingxia Gu 4 collaborations

Weiguang Yang 4 collaborations

Alison L Marsden 4 collaborations

James Chappell 3 collaborations

Purvesh Khatri 3 collaborations

Andrew J Sweatt 3 collaborations

Edda Spiekerkoetter 3 collaborations

Francois Haddad 3 collaborations

Roham T Zamanian 3 collaborations

Toshie Saito 3 collaborations

Shoichiro Otsuki 3 collaborations

Silin Sa 3 collaborations

Mark R Nicolls 3 collaborations

Melody Dong 3 collaborations

Jeffrey A Feinstein 3 collaborations

David P Marciano 3 collaborations

Minyi Shi 3 collaborations

Caiyun G Li 3 collaborations

Michele Donato 2 collaborations

Yifei Miao 2 collaborations

Kazuya Miyagawa 2 collaborations

Andrew Hsi 2 collaborations

Tsutomu Shinohara 2 collaborations

Jason M Szafron 2 collaborations

Sarasa Isobe 2 collaborations

Jesse M Engreitz 2 collaborations

Frandics P Chan 2 collaborations

Michelle Khau 2 collaborations

Karim Tabbane 2 collaborations

David Bloom 2 collaborations

Sherezad Abadi 2 collaborations

Celine Villemus 2 collaborations

Mark Rabinovitch 2 collaborations

Jai L Shah 2 collaborations

Alexandre Veillette 2 collaborations

Srividya N Iyer 2 collaborations

Patricia Boksa 2 collaborations

Ridha Joober 2 collaborations

Pin-I Chen 2 collaborations

Zhixin Zhao 2 collaborations

Diederik E van der Feen 1 collaboration

Guido P L Bossers 1 collaboration

Quint A J Hagdorn 1 collaboration

Kondababu Kurakula 1 collaboration

Robert Szulcek 1 collaboration

Francesco Vallania 1 collaboration

Klaas Kok 1 collaboration

Jaskaren S Kohli 1 collaboration

Arjen H Petersen 1 collaboration

Tom van Leusden 1 collaboration

Marco Demaria 1 collaboration

Marie-José T H Goumans 1 collaboration

Rudolf A De Boer 1 collaboration

Rolf M F Berger 1 collaboration

Beatrijs Bartelds 1 collaboration

Marcy Martin 1 collaboration

Jiao Zhang 1 collaboration

Ming He 1 collaboration

Jian Kang 1 collaboration

Hsi-Yuan Huang 1 collaboration

Chih-Hung Chou 1 collaboration

Tse-Shun Huang 1 collaboration

Hsiao-Chin Hong 1 collaboration

Shu-Han Su 1 collaboration

Simon S Wong 1 collaboration

Rakesh Bhattacharjee 1 collaboration

Hsien-Da Huang 1 collaboration

Zhen Bouman Chen 1 collaboration

Atul Malhotra 1 collaboration

James S Hagood 1 collaboration

John Y-J Shyy 1 collaboration

Myriam Amsallem 1 collaboration

Jennifer Arthur Ataam 1 collaboration

Julien Guihaire 1 collaboration

Florence Lecerf 1 collaboration

Mélanie Lambert 1 collaboration

Maria Rosa Ghigna 1 collaboration

Md Khadem Ali 1 collaboration

Yuqiang Mao 1 collaboration

Elie Fadel 1 collaboration

Vinicio de Jesus Perez 1 collaboration

Olaf Mercier 1 collaboration

Minzhe Guo 1 collaboration

Neil Wary 1 collaboration

Shuai Mao 1 collaboration

Christopher J Rhodes 1 collaboration

Patricia A Del Rosario 1 collaboration

Michal Bental-Roof 1 collaboration

Richard D Bland 1 collaboration

Emilia M Swietlik 1 collaboration

Stefan Gräf 1 collaboration

Martin R Wilkins 1 collaboration

Nicholas W Morrell 1 collaboration

Yoon Hong Chun 1 collaboration

Yannick C Lee-Yow 1 collaboration

Kenichi Okamura 1 collaboration

Jordan Kaplan 1 collaboration

Katherine Guo 1 collaboration

Benjamin D Franco 1 collaboration

Cholawat Pacharinsak 1 collaboration

Laura J Pisani 1 collaboration

Shinji Saitoh 1 collaboration

Yoshihide Mitani 1 collaboration

Jakob Körbelin 1 collaboration

Miranda K Culley 1 collaboration

Rashmi J Rao 1 collaboration

Monica Mehta 1 collaboration

Jingsi Zhao 1 collaboration

Wadih El Khoury 1 collaboration

Lloyd D Harvey 1 collaboration

Dror Perk 1 collaboration

Yi Yin Tai 1 collaboration

Ying Tang 1 collaboration

Sruti Shiva 1 collaboration

Thomas Bertero 1 collaboration

Stephen Y Chan 1 collaboration

Armando Reyes-Palomares 1 collaboration

Fabian Grubert 1 collaboration

Ivan Berest 1 collaboration

Maya Kasowski 1 collaboration

Christian Arnold 1 collaboration

Mao Shuai 1 collaboration

Rohith Srivas 1 collaboration

Simon Miao 1 collaboration

Judith B Zaugg 1 collaboration

John S Tamaresis 1 collaboration

Evan J Zucker 1 collaboration

Sahana Kumar 1 collaboration

Cristina M Orikaza 1 collaboration

Carina C Pessoa 1 collaboration

Fernanda V Paladino 1 collaboration

Pilar T V Florentino 1 collaboration

Clara L Barbiéri 1 collaboration

Hiro Goto 1 collaboration

Eduardo Milton Ramos-Sanchez 1 collaboration

José Franco da Silveira 1 collaboration

Michel Rabinovitch 1 collaboration

Renato A Mortara 1 collaboration

Fernando Real 1 collaboration

Sushma Reddy 1 collaboration

Stephanie Siehr Handler 1 collaboration

Sean Wu 1 collaboration

Gail Wright 1 collaboration

Elena A Goncharova 1 collaboration

Christophe Guignabert 1 collaboration

Kurt Stenmark 1 collaboration

Grazyna Kwapiszewska 1 collaboration

Norbert Voelkel 1 collaboration

Harm J Bogaard 1 collaboration

Brian Graham 1 collaboration

Soni S Pullamsetti 1 collaboration

Wolfgang M Kuebler 1 collaboration

Maria E Ariza 1 collaboration

Kelly C O Abud 1 collaboration

Clarisse M Machado 1 collaboration

Lucy S Vilas Boas 1 collaboration

Nair Y Maeda 1 collaboration

Eloisa S Carvalho 1 collaboration

Maria Francilene S Souza 1 collaboration

Paula V Gaiolla 1 collaboration

Claudia R P Castro 1 collaboration

Juliana Pereira 1 collaboration

Antonio Augusto Lopes 1 collaboration

Maxwell R Mumbach 1 collaboration

Fan Zhang 1 collaboration

Ramesh V Nair 1 collaboration

Joseph Nasser 1 collaboration

Daniel H Mai 1 collaboration

Ross J Metzger 1 collaboration

Howard Y Chang 1 collaboration

Nancy F Tojais 1 collaboration

Nesrine El-Bizri 1 collaboration

Yu-Mee Kim 1 collaboration

Kryn Stankunas 1 collaboration

Haley K Hedlin 1 collaboration

Vidhya Balasubramanian 1 collaboration

Lisa K Blum 1 collaboration

William H Robinson 1 collaboration

Peter M Hickey 1 collaboration

Robin Condliffe 1 collaboration

Allan Lawrie 1 collaboration

Wen Tian 1 collaboration

Xinguo Jiang 1 collaboration

Yon K Sung 1 collaboration

Eric Shuffle 1 collaboration

Ting-Hsuan Wu 1 collaboration

Peter N Kao 1 collaboration

Allen B Tu 1 collaboration

Peter Dorfmüller 1 collaboration

Gongyong Peng 1 collaboration

Yesl Kim 1 collaboration

Patrick Zhang 1 collaboration

Shravani Pasupneti 1 collaboration

Petra Dahms 1 collaboration

Peter Maguire 1 collaboration

Hassan Chaib 1 collaboration

Roham Zamanian 1 collaboration

Marc Peters-Golden 1 collaboration

Norbert F Voelkel 1 collaboration

Marc Humbert 1 collaboration

Jan K Hennigs 1 collaboration

Mouer Wang 1 collaboration

Ning-Yi Shao 1 collaboration

Tiffany Nguyen 1 collaboration

Elaine Yan 1 collaboration

Kévin Contrepois 1 collaboration

Joseph C Wu 1 collaboration