Mark Wappett

Affiliations

Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland BT9 7BL, United Kingdom.

Publications (9)

The pseudo-caspase FLIP(L) regulates cell fate following p53 activation.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Andrea Lees , Alexander J McIntyre , Nyree T Crawford , Fiammetta Falcone , Christopher McCann , Caitriona Holohan , Gerard P Quinn , Jamie Z Roberts , Tamas Sessler , Peter F Gallagher , Gemma M A Gregg , Katherine McAllister , Kirsty M McLaughlin , Wendy L Allen , Laurence J Egan , Aideen E Ryan , Melissa J Labonte-Wilson , Philip D Dunne , Mark Wappett , Vicky M Coyle , Patrick G Johnston , Emma M Kerr , Daniel B Longley , Simon S McDade

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.

Clinical and translational medicine

Avec: Anamarija Jurisic , Pei-Ju Sung , Mark Wappett , Julien Daubriac , Ian T Lobb , Wei-Wei Kung , Nyree Crawford , Natalie Page , Eamon Cassidy , Stephanie Feutren-Burton , J S Shane Rountree , Matthew D Helm , Colin R O'Dowd , Richard D Kennedy , Gerald Gavory , Aaron N Cranston , Daniel B Longley , Xavier Jacq , Timothy Harrison

classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes.

BMC bioinformatics

Avec: Gerard P Quinn , Tamas Sessler , Baharak Ahmaderaghi , Shauna Lambe , Harper VanSteenhouse , Mark Lawler , Mark Wappett , Bruce Seligmann , Daniel B Longley , Simon S McDade

surviveR: a flexible shiny application for patient survival analysis.

Scientific reports

Avec: Tamas Sessler , Gerard P Quinn , Mark Wappett , Emily Rogan , David Sharkey , Baharak Ahmaderaghi , Mark Lawler , Daniel B Longley , Simon S McDade

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

Molecular cancer therapeutics

Avec: Vera Grinkevitch , Mark Wappett , Nyree Crawford , Stacey Price , Andrea Lees , Christopher McCann , Katherine McAllister , Jochen Prehn , Jamie Young , Jess Bateson , Lewis Gallagher , Magali Michaut , Vivek Iyer , Aikaterini Chatzipli , Syd Barthorpe , Daniel Ciznadija , Ido Sloma , Amy Wesa , David A Tice , Lodewyk Wessels , Mathew Garnett , Daniel B Longley , Ultan McDermott , Simon S McDade

Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer.

Cell death discovery

Avec: Jennifer Ferris , Margarita Espona-Fiedler , Claudia Hamilton , Caitriona Holohan , Nyree Crawford , Alex J McIntyre , Jamie Z Roberts , Mark Wappett , Simon S McDade , Daniel B Longley , Victoria Coyle

SynLeGG: analysis and visualization of multiomics data for discovery of cancer 'Achilles Heels' and gene function relationships.

Nucleic acids research

Avec: Mark Wappett , Adam Harris , Alexander L R Lubbock , Ian Lobb , Simon McDade , Ian M Overton

Successful Proof-of-Concept for Topical Delivery of Novel Peptide ALM201 with Potential Usefulness for Treating Neovascular Eye Disorders.

Ophthalmology science

Avec: Gideon Obasanmi , M Andrew Nesbit , Diego Cobice , Logan Mackay , Stuart McGimpsey , Mark Wappett , Aaron N Cranston , Tara C B Moore

Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.

Scientific reports

Avec: Natalie Page , Mark Wappett , Colin R O'Dowd , Martin O'Rourke , Gerald Gavory , Lixin Zhang , J S Shane Rountree , Linda Jordan , Oliver Barker , Hayley Gibson , Caroline Boyd , Stephanie Feutren-Burton , Estelle McLean , Graham Trevitt , Timothy Harrison

Réseau de co-auteurs

Daniel B Longley 6 collaborations

Simon S McDade 5 collaborations

Gerard P Quinn 3 collaborations

Tamas Sessler 3 collaborations

Nyree Crawford 3 collaborations

Andrea Lees 2 collaborations

Christopher McCann 2 collaborations

Caitriona Holohan 2 collaborations

Jamie Z Roberts 2 collaborations

Katherine McAllister 2 collaborations

Natalie Page 2 collaborations

Stephanie Feutren-Burton 2 collaborations

J S Shane Rountree 2 collaborations

Colin R O'Dowd 2 collaborations

Gerald Gavory 2 collaborations

Aaron N Cranston 2 collaborations

Timothy Harrison 2 collaborations

Baharak Ahmaderaghi 2 collaborations

Mark Lawler 2 collaborations

Alexander J McIntyre 1 collaboration

Nyree T Crawford 1 collaboration

Fiammetta Falcone 1 collaboration

Peter F Gallagher 1 collaboration

Gemma M A Gregg 1 collaboration

Kirsty M McLaughlin 1 collaboration

Wendy L Allen 1 collaboration

Laurence J Egan 1 collaboration

Aideen E Ryan 1 collaboration

Melissa J Labonte-Wilson 1 collaboration

Philip D Dunne 1 collaboration

Vicky M Coyle 1 collaboration

Patrick G Johnston 1 collaboration

Emma M Kerr 1 collaboration

Anamarija Jurisic 1 collaboration

Pei-Ju Sung 1 collaboration

Julien Daubriac 1 collaboration

Ian T Lobb 1 collaboration

Wei-Wei Kung 1 collaboration

Eamon Cassidy 1 collaboration

Matthew D Helm 1 collaboration

Richard D Kennedy 1 collaboration

Xavier Jacq 1 collaboration

Shauna Lambe 1 collaboration

Harper VanSteenhouse 1 collaboration

Bruce Seligmann 1 collaboration

Emily Rogan 1 collaboration

David Sharkey 1 collaboration

Vera Grinkevitch 1 collaboration

Stacey Price 1 collaboration

Jochen Prehn 1 collaboration

Jamie Young 1 collaboration

Jess Bateson 1 collaboration

Lewis Gallagher 1 collaboration

Magali Michaut 1 collaboration

Vivek Iyer 1 collaboration

Aikaterini Chatzipli 1 collaboration

Syd Barthorpe 1 collaboration

Daniel Ciznadija 1 collaboration

Ido Sloma 1 collaboration

Amy Wesa 1 collaboration

David A Tice 1 collaboration

Lodewyk Wessels 1 collaboration

Mathew Garnett 1 collaboration

Ultan McDermott 1 collaboration

Jennifer Ferris 1 collaboration

Margarita Espona-Fiedler 1 collaboration

Claudia Hamilton 1 collaboration

Alex J McIntyre 1 collaboration

Victoria Coyle 1 collaboration

Adam Harris 1 collaboration

Alexander L R Lubbock 1 collaboration

Ian Lobb 1 collaboration

Simon McDade 1 collaboration

Ian M Overton 1 collaboration

Gideon Obasanmi 1 collaboration

M Andrew Nesbit 1 collaboration

Diego Cobice 1 collaboration

Logan Mackay 1 collaboration

Stuart McGimpsey 1 collaboration

Tara C B Moore 1 collaboration

Martin O'Rourke 1 collaboration

Lixin Zhang 1 collaboration

Linda Jordan 1 collaboration

Oliver Barker 1 collaboration

Hayley Gibson 1 collaboration

Caroline Boyd 1 collaboration

Estelle McLean 1 collaboration

Graham Trevitt 1 collaboration