Margaret Tarpley

Affiliations

University of Botswana Department of Medical Education, Gaborone, Botswana.

Publications (11)

Data supporting a pilot high-throughput screen of a drug library for identification of DYRK1A inhibitors and high-content imaging analysis of identified harmine analogs.

Data in brief

Avec: Michael Tarpley , Helen Oladapo , Thomas B Caligan , Rob U Onyenwoke , Kevin P Williams

Genome-Wide Binding Analysis of DNA Repair Protein APE1 in Tumor Cells by ChIP-Seq.

Methods in molecular biology (Clifton, N.J.)

Avec: Mason Tarpley , Yingling Chen , Kishor K Bhakat

Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Michael Tarpley , Helen O Oladapo , Dillon Strepay , Thomas B Caligan , Lhoucine Chdid , Hassan Shehata , Jose R Roques , Rhashad Thomas , Christopher P Laudeman , Rob U Onyenwoke , David B Darr , Kevin P Williams

Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Shrabasti Roychoudhury , Suravi Pramanik , Hannah L Harris , Mason Tarpley , Aniruddha Sarkar , Gaelle Spagnol , Paul L Sorgen , Dipanjan Chowdhury , Vimla Band , David Klinkebiel , Kishor K Bhakat

Academic Global Surgery Curricula: Current Status and a Call for a More Equitable Approach.

The Journal of surgical research

Avec: Anusha Jayaram , Natalie Pawlak , Alexis Kahanu , Parisa Fallah , Haniee Chung , Nancy Valencia-Rojas , Edgar B Rodas , Ahmadreza Abbaslou , Adnan Alseidi , Emmanuel A Ameh , Abebe Bekele , Kathleen Casey , Kathryn Chu , Robert Dempsey , Chris Dodgion , Randeep Jawa , Maria F Jimenez , Walt Johnson , Sanjay Krishnaswami , Gifty Kwakye , Robert Lane , Kokila Lakhoo , Kristin Long , Katayoun Madani , Fiemu Nwariaku , Benedict Nwomeh , Raymond Price , Steven Roser , Andrew B Rees , Nobhojit Roy , Nensi Melissa Ruzgar , Hernan Sacoto , Ziad Sifri , Nichole Starr , Mamta Swaroop , Margaret Tarpley , John Tarpley , Girma Terfera , Thomas Weiser , Michael Lipnick , Mary Nabukenya , Doruk Ozgediz , Sudha Jayaraman

Identifying knowledge needed to improve surgical care in Southern Africa using a theory of change approach.

BMJ global health

Avec: Danyca Shadé Breedt , Maria Lisa Odland , Balisi Bakanisi , Edward Clune , Moneimang Makgasa , John Tarpley , Margaret Tarpley , Akutu Munyika , Jacob Sheehama , Theresia Shivera , Bruce Biccard , Regan Boden , Sean Chetty , Liesl de Waard , Rowan Duys , Kristin Groeneveld , Susan Levine , Tamlyn Mac Quene , Salome Maswime , Megan Naidoo , Priyanka Naidu , Shrikant Peters , Ché L Reddy , Savannah Verhage , Godfrey Muguti , Shingai Nyaguse , Lucia D'Ambruoso , Kathryn Chu , Justine I Davies , Auteur inconnu

Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction.

Scientific reports

Avec: Eric W Fish , Laura B Murdaugh , Chengjin Zhang , Karen E Boschen , Oswald Boa-Amponsem , Haley N Mendoza-Romero , Michael Tarpley , Lhoucine Chdid , Somnath Mukhopadhyay , Gregory J Cole , Kevin P Williams , Scott E Parnell

Optimization and validation of a DYRK1A TR-FRET assay for high-throughput screening.

MethodsX

Avec: Michael Tarpley , Thomas B Caligan , Rob U Onyenwoke , Kevin P Williams

Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder.

Journal of neuroscience research

Avec: Derek F Burton , Oswald M Boa-Amponsem , Maria S Dixon , Michael J Hopkins , Te-Andre Herbin , Shiquita Toney , Michael Tarpley , Blanca V Rodriguez , Eric W Fish , Scott E Parnell , Gregory J Cole , Kevin P Williams

Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells.

Molecules (Basel, Switzerland)

Avec: Dina Abu Rabe , Lhoucine Chdid , David R Lamson , Christopher P Laudeman , Michael Tarpley , Naglaa Elsayed , Ginger R Smith , Weifan Zheng , Maria S Dixon , Kevin P Williams

Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays.

Biochimica et biophysica acta. General subjects

Avec: David R Lamson , Michael Tarpley , Kezia Addo , Xiaojia Ji , Dina Abu Rabe , Ben Ehe , Mark Hughes , Ginger R Smith , Laura R Daye , David L Musso , Weifan Zheng , Kevin P Williams

Réseau de co-auteurs

Michael Tarpley 7 collaborations

Kevin P Williams 7 collaborations

Thomas B Caligan 3 collaborations

Rob U Onyenwoke 3 collaborations

Lhoucine Chdid 3 collaborations

Mason Tarpley 2 collaborations

Kishor K Bhakat 2 collaborations

Christopher P Laudeman 2 collaborations

Kathryn Chu 2 collaborations

John Tarpley 2 collaborations

Eric W Fish 2 collaborations

Gregory J Cole 2 collaborations

Scott E Parnell 2 collaborations

Maria S Dixon 2 collaborations

Dina Abu Rabe 2 collaborations

David R Lamson 2 collaborations

Ginger R Smith 2 collaborations

Weifan Zheng 2 collaborations

Helen Oladapo 1 collaboration

Yingling Chen 1 collaboration

Helen O Oladapo 1 collaboration

Dillon Strepay 1 collaboration

Hassan Shehata 1 collaboration

Jose R Roques 1 collaboration

Rhashad Thomas 1 collaboration

David B Darr 1 collaboration

Shrabasti Roychoudhury 1 collaboration

Suravi Pramanik 1 collaboration

Hannah L Harris 1 collaboration

Aniruddha Sarkar 1 collaboration

Gaelle Spagnol 1 collaboration

Paul L Sorgen 1 collaboration

Dipanjan Chowdhury 1 collaboration

Vimla Band 1 collaboration

David Klinkebiel 1 collaboration

Anusha Jayaram 1 collaboration

Natalie Pawlak 1 collaboration

Alexis Kahanu 1 collaboration

Parisa Fallah 1 collaboration

Haniee Chung 1 collaboration

Nancy Valencia-Rojas 1 collaboration

Edgar B Rodas 1 collaboration

Ahmadreza Abbaslou 1 collaboration

Adnan Alseidi 1 collaboration

Emmanuel A Ameh 1 collaboration

Abebe Bekele 1 collaboration

Kathleen Casey 1 collaboration

Robert Dempsey 1 collaboration

Chris Dodgion 1 collaboration

Randeep Jawa 1 collaboration

Maria F Jimenez 1 collaboration

Walt Johnson 1 collaboration

Sanjay Krishnaswami 1 collaboration

Gifty Kwakye 1 collaboration

Robert Lane 1 collaboration

Kokila Lakhoo 1 collaboration

Kristin Long 1 collaboration

Katayoun Madani 1 collaboration

Fiemu Nwariaku 1 collaboration

Benedict Nwomeh 1 collaboration

Raymond Price 1 collaboration

Steven Roser 1 collaboration

Andrew B Rees 1 collaboration

Nobhojit Roy 1 collaboration

Nensi Melissa Ruzgar 1 collaboration

Hernan Sacoto 1 collaboration

Ziad Sifri 1 collaboration

Nichole Starr 1 collaboration

Mamta Swaroop 1 collaboration

Girma Terfera 1 collaboration

Thomas Weiser 1 collaboration

Michael Lipnick 1 collaboration

Mary Nabukenya 1 collaboration

Doruk Ozgediz 1 collaboration

Sudha Jayaraman 1 collaboration

Danyca Shadé Breedt 1 collaboration

Maria Lisa Odland 1 collaboration

Balisi Bakanisi 1 collaboration

Edward Clune 1 collaboration

Moneimang Makgasa 1 collaboration

Akutu Munyika 1 collaboration

Jacob Sheehama 1 collaboration

Theresia Shivera 1 collaboration

Bruce Biccard 1 collaboration

Regan Boden 1 collaboration

Sean Chetty 1 collaboration

Liesl de Waard 1 collaboration

Rowan Duys 1 collaboration

Kristin Groeneveld 1 collaboration

Susan Levine 1 collaboration

Tamlyn Mac Quene 1 collaboration

Salome Maswime 1 collaboration

Megan Naidoo 1 collaboration

Priyanka Naidu 1 collaboration

Shrikant Peters 1 collaboration

Ché L Reddy 1 collaboration

Savannah Verhage 1 collaboration

Godfrey Muguti 1 collaboration

Shingai Nyaguse 1 collaboration

Lucia D'Ambruoso 1 collaboration

Justine I Davies 1 collaboration

None None 1 collaboration

Laura B Murdaugh 1 collaboration

Chengjin Zhang 1 collaboration

Karen E Boschen 1 collaboration

Oswald Boa-Amponsem 1 collaboration

Haley N Mendoza-Romero 1 collaboration

Somnath Mukhopadhyay 1 collaboration

Derek F Burton 1 collaboration

Oswald M Boa-Amponsem 1 collaboration

Michael J Hopkins 1 collaboration

Te-Andre Herbin 1 collaboration

Shiquita Toney 1 collaboration

Blanca V Rodriguez 1 collaboration

Naglaa Elsayed 1 collaboration

Kezia Addo 1 collaboration

Xiaojia Ji 1 collaboration

Ben Ehe 1 collaboration

Mark Hughes 1 collaboration

Laura R Daye 1 collaboration

David L Musso 1 collaboration