Marco Pirazzini

Affiliations

Dipartimento di Scienze Biomediche, Università di Padova, Padua, Italy.

Publications (28)

The role of the single interchains disulfide bond in tetanus and botulinum neurotoxins and the development of antitetanus and antibotulism drugs.

Cellular microbiology

Avec: Ornella Rossetto , Marco Pirazzini , Florigio Lista , Cesare Montecucco

Models and methods to study Schwann cells.

Journal of anatomy

Avec: Samuele Negro , Marco Pirazzini , Michela Rigoni

Facial neuromuscular junctions and brainstem nuclei are the target of tetanus neurotoxin in cephalic tetanus.

JCI insight

Avec: Federico Fabris , Stefano Varani , Marika Tonellato , Ivica Matak , Petra Šoštarić , Patrik Meglić , Matteo Caleo , Aram Megighian , Ornella Rossetto , Cesare Montecucco , Marco Pirazzini

Three players in the 'toxic affair' between botulinum neurotoxin type A and neurons.

Trends in neurosciences

Avec: Ornella Rossetto , Marco Pirazzini , Cesare Montecucco

Botulinum Neurotoxins: Mechanism of Action.

Handbook of experimental pharmacology

Avec: O Rossetto , M Pirazzini , F Fabris , C Montecucco

An Agonist of the CXCR4 Receptor Strongly Promotes Regeneration of Degenerated Motor Axon Terminals.

Cells

Avec: Samuele Negro , Giulia Zanetti , Andrea Mattarei , Alice Valentini , Aram Megighian , Giulia Tombesi , Alessandro Zugno , Valentina Dianin , Marco Pirazzini , Silvia Fillo , Florigio Lista , Michela Rigoni , Cesare Montecucco

An agonist of CXCR4 induces a rapid recovery from the neurotoxic effects of Vipera ammodytes and Vipera aspis venoms.

Journal of neurochemistry

Avec: M Stazi , A Megighian , G D'Este , S Negro , A Ivanušec , D Lonati , M Pirazzini , I Križaj , C Montecucco

Introduction to the Special Issue "Skeletal Muscle Atrophy: Mechanisms at a Cellular Level".

Cells

Avec: Emanuela Zuccaro , Caterina Marchioretti , Marco Pirazzini , Maria Pennuto

Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration.

International journal of molecular sciences

Avec: Giorgia D'Este , Marco Stazi , Samuele Negro , Aram Megighian , Florigio Lista , Ornella Rossetto , Cesare Montecucco , Michela Rigoni , Marco Pirazzini

Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody.

International journal of molecular sciences

Avec: Federico Fabris , Petra Šoštarić , Ivica Matak , Thomas Binz , Anna Toffan , Morena Simonato , Cesare Montecucco , Marco Pirazzini , Ornella Rossetto

A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage.

Annals of clinical and translational neurology

Avec: Giulia Zanetti , Samuele Negro , Aram Megighian , Andrea Mattarei , Florigio Lista , Silvia Fillo , Michela Rigoni , Marco Pirazzini , Cesare Montecucco

Paper-based electrochemical peptide sensor for on-site detection of botulinum neurotoxin serotype A and C.

Biosensors & bioelectronics

Avec: Veronica Caratelli , Silvia Fillo , Nino D'Amore , Ornella Rossetto , Marco Pirazzini , Maria Moccia , Concetta Avitabile , Danila Moscone , Florigio Lista , Fabiana Arduini

Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo.

Journal of the American Chemical Society

Avec: Francesca Mastrotto , Marco Pirazzini , Samuele Negro , Alan Salama , Luisa Martinez-Pomares , Giuseppe Mantovani

Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor.

Acta neuropathologica communications

Avec: Samuele Negro , Fabio Lauria , Marco Stazi , Toma Tebaldi , Giorgia D'Este , Marco Pirazzini , Aram Megighian , Francesca Lessi , Chiara M Mazzanti , Gabriele Sales , Chiara Romualdi , Silvia Fillo , Florigio Lista , James N Sleigh , Andrew P Tosolini , Giampietro Schiavo , Gabriella Viero , Michela Rigoni

Beyond neuromuscular activity: botulinum toxin type A exerts direct central action on spinal control of movement.

European journal of pharmacology

Avec: Petra Šoštarić , Magdalena Matić , Dalia Nemanić , Željka Lučev Vasić , Mario Cifrek , Marco Pirazzini , Ivica Matak

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex.

The EMBO journal

Avec: Sunaina Surana , David Villarroel-Campos , Elena R Rhymes , Maria Kalyukina , Chiara Panzi , Sergey S Novoselov , Federico Fabris , Sandy Richter , Marco Pirazzini , Giuseppe Zanotti , James N Sleigh , Giampietro Schiavo

Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets.

Journal of neurochemistry

Avec: Aram Megighian , Marco Pirazzini , Federico Fabris , Ornella Rossetto , Cesare Montecucco

Skeletal muscle mTORC1 regulates neuromuscular junction stability.

Journal of cachexia, sarcopenia and muscle

Avec: Martina Baraldo , Alessia Geremia , Marco Pirazzini , Leonardo Nogara , Francesca Solagna , Clara Türk , Hendrik Nolte , Vanina Romanello , Aram Megighian , Simona Boncompagni , Marcus Kruger , Marco Sandri , Bert Blaauw

Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism.

Cells

Avec: Mathilde Chivet , Caterina Marchioretti , Marco Pirazzini , Diana Piol , Chiara Scaramuzzino , Maria Josè Polanco , Vanina Romanello , Emanuela Zuccaro , Sara Parodi , Maurizio D'Antonio , Carlo Rinaldi , Fabio Sambataro , Elena Pegoraro , Gianni Soraru , Udai Bhan Pandey , Marco Sandri , Manuela Basso , Maria Pennuto

Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.

The Journal of clinical investigation

Avec: Marco Pirazzini , Alessandro Grinzato , Davide Corti , Sonia Barbieri , Oneda Leka , Francesca Vallese , Marika Tonellato , Chiara Silacci-Fregni , Luca Piccoli , Eaazhisai Kandiah , Giampietro Schiavo , Giuseppe Zanotti , Antonio Lanzavecchia , Cesare Montecucco

Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin.

Pharmaceuticals (Basel, Switzerland)

Avec: Giulia Zanetti , Andrea Mattarei , Florigio Lista , Ornella Rossetto , Cesare Montecucco , Marco Pirazzini

Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update.

Archives of toxicology

Avec: Marco Pirazzini , Cesare Montecucco , Ornella Rossetto

Local tetanus begins with a VAMP cleavage-associated neuromuscular junction paralysis around the site of tetanus neurotoxin release.

The American journal of pathology

Avec: Federico Fabris , Aram Megighian , Ornella Rossetto , Morena Simonato , Giampietro Schiavo , Marco Pirazzini , Cesare Montecucco

Mannosylated Polycations Target CD206

Biomacromolecules

Avec: Federica Bellato , Sara Feola , Gloria Dalla Verde , Greta Bellio , Marco Pirazzini , Stefano Salmaso , Paolo Caliceti , Vincenzo Cerullo , Francesca Mastrotto

Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca

Nature communications

Avec: Caterina Marchioretti , Giulia Zanetti , Marco Pirazzini , Gaia Gherardi , Leonardo Nogara , Roberta Andreotti , Paolo Martini , Lorenzo Marcucci , Marta Canato , Samir R Nath , Emanuela Zuccaro , Mathilde Chivet , Cristina Mammucari , Marco Pacifici , Anna Raffaello , Rosario Rizzuto , Andrea Mattarei , Maria A Desbats , Leonardo Salviati , Aram Megighian , Gianni Sorarù , Elena Pegoraro , Elisa Belluzzi , Assunta Pozzuoli , Carlo Biz , Pietro Ruggieri , Chiara Romualdi , Andrew P Lieberman , Gopal J Babu , Marco Sandri , Bert Blaauw , Manuela Basso , Maria Pennuto

Measuring utility with diffusion models.

Science advances

Avec: Renato Berlinghieri , Ian Krajbich , Fabio Maccheroni , Massimo Marinacci , Marco Pirazzini

A DARPin promotes faster onset of botulinum neurotoxin A1 action.

Nature communications

Avec: Oneda Leka , Yufan Wu , Giulia Zanetti , Sven Furler , Thomas Reinberg , Joana Marinho , Jonas V Schaefer , Andreas Plückthun , Xiaodan Li , Marco Pirazzini , Richard A Kammerer

Excitation-contraction coupling inhibitors potentiate the actions of botulinum neurotoxin type A at the neuromuscular junction.

British journal of pharmacology

Avec: Mickaël Machicoane , Marika Tonellato , Marica Zainotto , Paul Onillon , Marco Stazi , Mattia Dal Corso , Aram Megighian , Ornella Rossetto , Jean-Marc Le Doussal , Marco Pirazzini

Réseau de co-auteurs

Cesare Montecucco 12 collaborations

Ornella Rossetto 11 collaborations

Aram Megighian 10 collaborations

Florigio Lista 7 collaborations

Samuele Negro 6 collaborations

Michela Rigoni 5 collaborations

Federico Fabris 5 collaborations

Giulia Zanetti 5 collaborations

Andrea Mattarei 4 collaborations

Silvia Fillo 4 collaborations

Giampietro Schiavo 4 collaborations

Marika Tonellato 3 collaborations

Ivica Matak 3 collaborations

Petra Šoštarić 3 collaborations

Emanuela Zuccaro 3 collaborations

Caterina Marchioretti 3 collaborations

Maria Pennuto 3 collaborations

Marco Stazi 3 collaborations

Marco Sandri 3 collaborations

M Pirazzini 2 collaborations

C Montecucco 2 collaborations

Giorgia D'Este 2 collaborations

Morena Simonato 2 collaborations

Francesca Mastrotto 2 collaborations

Chiara Romualdi 2 collaborations

James N Sleigh 2 collaborations

Giuseppe Zanotti 2 collaborations

Leonardo Nogara 2 collaborations

Vanina Romanello 2 collaborations

Bert Blaauw 2 collaborations

Mathilde Chivet 2 collaborations

Elena Pegoraro 2 collaborations

Manuela Basso 2 collaborations

Oneda Leka 2 collaborations

Stefano Varani 1 collaboration

Patrik Meglić 1 collaboration

Matteo Caleo 1 collaboration

O Rossetto 1 collaboration

F Fabris 1 collaboration

Alice Valentini 1 collaboration

Giulia Tombesi 1 collaboration

Alessandro Zugno 1 collaboration

Valentina Dianin 1 collaboration

M Stazi 1 collaboration

A Megighian 1 collaboration

G D'Este 1 collaboration

S Negro 1 collaboration

A Ivanušec 1 collaboration

D Lonati 1 collaboration

I Križaj 1 collaboration

Thomas Binz 1 collaboration

Anna Toffan 1 collaboration

Veronica Caratelli 1 collaboration

Nino D'Amore 1 collaboration

Maria Moccia 1 collaboration

Concetta Avitabile 1 collaboration

Danila Moscone 1 collaboration

Fabiana Arduini 1 collaboration

Alan Salama 1 collaboration

Luisa Martinez-Pomares 1 collaboration

Giuseppe Mantovani 1 collaboration

Fabio Lauria 1 collaboration

Toma Tebaldi 1 collaboration

Francesca Lessi 1 collaboration

Chiara M Mazzanti 1 collaboration

Gabriele Sales 1 collaboration

Andrew P Tosolini 1 collaboration

Gabriella Viero 1 collaboration

Magdalena Matić 1 collaboration

Dalia Nemanić 1 collaboration

Željka Lučev Vasić 1 collaboration

Mario Cifrek 1 collaboration

Sunaina Surana 1 collaboration

David Villarroel-Campos 1 collaboration

Elena R Rhymes 1 collaboration

Maria Kalyukina 1 collaboration

Chiara Panzi 1 collaboration

Sergey S Novoselov 1 collaboration

Sandy Richter 1 collaboration

Martina Baraldo 1 collaboration

Alessia Geremia 1 collaboration

Francesca Solagna 1 collaboration

Clara Türk 1 collaboration

Hendrik Nolte 1 collaboration

Simona Boncompagni 1 collaboration

Marcus Kruger 1 collaboration

Diana Piol 1 collaboration

Chiara Scaramuzzino 1 collaboration

Maria Josè Polanco 1 collaboration

Sara Parodi 1 collaboration

Maurizio D'Antonio 1 collaboration

Carlo Rinaldi 1 collaboration

Fabio Sambataro 1 collaboration

Gianni Soraru 1 collaboration

Udai Bhan Pandey 1 collaboration

Alessandro Grinzato 1 collaboration

Davide Corti 1 collaboration

Sonia Barbieri 1 collaboration

Francesca Vallese 1 collaboration

Chiara Silacci-Fregni 1 collaboration

Luca Piccoli 1 collaboration

Eaazhisai Kandiah 1 collaboration

Antonio Lanzavecchia 1 collaboration

Federica Bellato 1 collaboration

Sara Feola 1 collaboration

Gloria Dalla Verde 1 collaboration

Greta Bellio 1 collaboration

Stefano Salmaso 1 collaboration

Paolo Caliceti 1 collaboration

Vincenzo Cerullo 1 collaboration

Gaia Gherardi 1 collaboration

Roberta Andreotti 1 collaboration

Paolo Martini 1 collaboration

Lorenzo Marcucci 1 collaboration

Marta Canato 1 collaboration

Samir R Nath 1 collaboration

Cristina Mammucari 1 collaboration

Marco Pacifici 1 collaboration

Anna Raffaello 1 collaboration

Rosario Rizzuto 1 collaboration

Maria A Desbats 1 collaboration

Leonardo Salviati 1 collaboration

Gianni Sorarù 1 collaboration

Elisa Belluzzi 1 collaboration

Assunta Pozzuoli 1 collaboration

Carlo Biz 1 collaboration

Pietro Ruggieri 1 collaboration

Andrew P Lieberman 1 collaboration

Gopal J Babu 1 collaboration

Renato Berlinghieri 1 collaboration

Ian Krajbich 1 collaboration

Fabio Maccheroni 1 collaboration

Massimo Marinacci 1 collaboration

Yufan Wu 1 collaboration

Sven Furler 1 collaboration

Thomas Reinberg 1 collaboration

Joana Marinho 1 collaboration

Jonas V Schaefer 1 collaboration

Andreas Plückthun 1 collaboration

Xiaodan Li 1 collaboration

Richard A Kammerer 1 collaboration

Mickaël Machicoane 1 collaboration

Marica Zainotto 1 collaboration

Paul Onillon 1 collaboration

Mattia Dal Corso 1 collaboration

Jean-Marc Le Doussal 1 collaboration