Manuel Vázquez-Carrera

Affiliations

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III, Spain; Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain. Electronic address: mvazquezcarrera@ub.edu.

Publications (34)

Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes.

Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis

Avec: Mohammad Zarei , Emma Barroso , Xavier Palomer , Joan Carles Escolà-Gil , Lidia Cedó , Walter Wahli , Manuel Vázquez-Carrera

Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes.

Metabolism: clinical and experimental

Avec: Ricardo Rodríguez-Calvo , Josefa Girona , Marina Rodríguez , Sara Samino , Emma Barroso , David de Gonzalo-Calvo , Sandra Guaita-Esteruelas , Mercedes Heras , Rutger W van der Meer , Hildo J Lamb , Oscar Yanes , Xavier Correig , Vicenta Llorente-Cortés , Manuel Vázquez-Carrera , Lluis Masana

SIRT1 regulates hepatic vldlr levels.

Cell communication and signaling : CCS

Avec: Mona Peyman , Anna Babin-Ebell , Rosalía Rodríguez-Rodríguez , Matilde Rigon , David Aguilar-Recarte , Joan Villarroya , Anna Planavila , Francesc Villarroya , Xavier Palomer , Emma Barroso , Manuel Vázquez-Carrera

From the Design to the

Journal of medicinal chemistry

Avec: Sandra Codony , Carla Calvó-Tusell , Elena Valverde , Sílvia Osuna , Christophe Morisseau , M Isabel Loza , José Brea , Concepción Pérez , María Isabel Rodríguez-Franco , Javier Pizarro-Delgado , Rubén Corpas , Christian Griñán-Ferré , Mercè Pallàs , Coral Sanfeliu , Manuel Vázquez-Carrera , Bruce D Hammock , Ferran Feixas , Santiago Vázquez

A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.

Pharmacological research

Avec: David Aguilar-Recarte , Emma Barroso , Meijian Zhang , Patricia Rada , Javier Pizarro-Delgado , Lucía Peña , Xavier Palomer , Ángela M Valverde , Walter Wahli , Manuel Vázquez-Carrera

Comparison between aerobic exercise training and enalapril treatment as tools to improve diet-induced metabolic-associated fatty liver disease: Effects on endoplasmic reticulum stress markers.

Life sciences

Avec: Vinicius Sepúlveda-Fragoso , Beatriz Alexandre-Santos , Emanuelle Barreto-Reis , Tiago Fernandes , Edilamar Menezes Oliveira , Soraia das Neves Vieira Cavalcanti , Georgia Correa Atella , Leandro Miranda-Alves , Manuel Vázquez-Carrera , Antonio Claudio Lucas da Nóbrega , Eliete Dalla Corte Frantz , D'Angelo Carlo Magliano

GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway.

Metabolism: clinical and experimental

Avec: Javier Jurado-Aguilar , Emma Barroso , Maribel Bernard , Meijian Zhang , Mona Peyman , Patricia Rada , Ángela M Valverde , Walter Wahli , Xavier Palomer , Manuel Vázquez-Carrera

Role of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model.

Journal of neurochemistry

Avec: Oriol Busquets , Àuria Eritja , Blanca M López , Miren Ettcheto , Patricia R Manzine , Rubén D Castro-Torres , Ester Verdaguer , Jordi Olloquequi , Manuel Vázquez-Carrera , Carme Auladell , Jaume Folch , Antoni Camins

Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.

British journal of pharmacology

Avec: Mohammad Zarei , Eugènia Pujol , Tania Quesada-López , Francesc Villarroya , Emma Barroso , Santiago Vázquez , Javier Pizarro-Delgado , Xavier Palomer , Manuel Vázquez-Carrera

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance.

International journal of molecular sciences

Avec: David Aguilar-Recarte , Xavier Palomer , Walter Wahli , Manuel Vázquez-Carrera

Design and Synthesis of AMPK Activators and GDF15 Inducers.

Molecules (Basel, Switzerland)

Avec: Meijian Zhang , Andrea Bagán , Donna Martínez , Emma Barroso , Xavier Palomer , Santiago Vázquez , Carmen Escolano , Manuel Vázquez-Carrera

Increased hepatic gluconeogenesis and type 2 diabetes mellitus.

Trends in endocrinology and metabolism: TEM

Avec: Emma Barroso , Javier Jurado-Aguilar , Walter Wahli , Xavier Palomer , Manuel Vázquez-Carrera

PPARs as Key Transcription Regulators at the Crossroads of Metabolism and Inflammation.

International journal of molecular sciences

Avec: Manuel Vázquez-Carrera , Walter Wahli

GADD45A: With or without you.

Medicinal research reviews

Avec: Xavier Palomer , Jesús M Salvador , Christian Griñán-Ferré , Emma Barroso , Mercè Pallàs , Manuel Vázquez-Carrera

CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns.

Cell communication and signaling : CCS

Avec: Emma Barroso , Marta Díaz , Ana Cristina Reguera , Mona Peyman , Jesús Balsinde , Javier Jurado-Aguilar , Meijian Zhang , Adel Rostami , Xavier Palomer , Lourdes Ibáñez , Manuel Vázquez-Carrera

Targeting FGF21 for the Treatment of Nonalcoholic Steatohepatitis.

Trends in pharmacological sciences

Avec: Mohammad Zarei , Javier Pizarro-Delgado , Emma Barroso , Xavier Palomer , Manuel Vázquez-Carrera

SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2.

Cell communication and signaling : CCS

Avec: Emma Barroso , Rosalía Rodríguez-Rodríguez , Mohammad Zarei , Javier Pizarro-Degado , Anna Planavila , Xavier Palomer , Francesc Villarroya , Manuel Vázquez-Carrera

CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.

Frontiers in immunology

Avec: Ester Sala , Celia Vived , Júlia Luna , Noemí Alejandra Saavedra-Ávila , Upasana Sengupta , A Raúl Castaño , Sabrina Villar-Pazos , Laura Haba , Joan Verdaguer , Ana B Ropero , Thomas Stratmann , Javier Pizarro , Manuel Vázquez-Carrera , Angel Nadal , Jill M Lahti , Conchi Mora

Endoplasmic reticulum stress downregulates PGC-1α in skeletal muscle through ATF4 and an mTOR-mediated reduction of CRTC2.

Cell communication and signaling : CCS

Avec: Marta Montori-Grau , David Aguilar-Recarte , Mohammad Zarei , Javier Pizarro-Delgado , Xavier Palomer , Manuel Vázquez-Carrera

PPARs as Key Mediators in the Regulation of Metabolism and Inflammation.

International journal of molecular sciences

Avec: Manuel Vázquez-Carrera , Walter Wahli

Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Mona Peyman , Emma Barroso , Andreea L Turcu , Francesc Estrany , Dáire Smith , Javier Jurado-Aguilar , Patricia Rada , Christophe Morisseau , Bruce D Hammock , Ángela M Valverde , Xavier Palomer , Carles Galdeano , Santiago Vázquez , Manuel Vázquez-Carrera

Peroxisomal Proliferator-Activated Receptor

Frontiers in pharmacology

Avec: Triana Espinosa-Jiménez , Oriol Busquets , Amanda Cano , Elena Sánchez-López , Ester Verdaguer , Antoni Parcerisas , Jordi Olloquequi , Carme Auladell , Jaume Folch , Walter Wahli , Manuel Vázquez-Carrera , Antoni Camins , Miren Ettcheto

11β-HSD1 Inhibition Rescues SAMP8 Cognitive Impairment Induced by Metabolic Stress.

Molecular neurobiology

Avec: Dolors Puigoriol-Illamola , Rosana Leiva , Manel Vázquez-Carrera , Santiago Vázquez , Christian Griñán-Ferré , Mercè Pallàs

Reconfigurable multiplexed point of Care System for monitoring type 1 diabetes patients.

Biosensors & bioelectronics

Avec: Augusto Márquez , Joan Aymerich , Michele Dei , Rosalía Rodríguez-Rodríguez , Manuel Vázquez-Carrera , Javier Pizarro-Delgado , Pablo Giménez-Gómez , Ángel Merlos , Lluís Terés , Francesc Serra-Graells , Cecilia Jiménez-Jorquera , Carlos Domínguez , Xavier Muñoz-Berbel

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation.

Signal transduction and targeted therapy

Avec: Xavier Palomer , M Silvia Román-Azcona , Javier Pizarro-Delgado , Ana Planavila , Francesc Villarroya , Brenda Valenzuela-Alcaraz , Fátima Crispi , Álvaro Sepúlveda-Martínez , Irene Miguel-Escalada , Jorge Ferrer , J Francisco Nistal , Raquel García , Mercy M Davidson , Emma Barroso , Manuel Vázquez-Carrera

Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease.

Metabolism: clinical and experimental

Avec: Mohammad Zarei , David Aguilar-Recarte , Xavier Palomer , Manuel Vázquez-Carrera

Crosstalk between the renin-angiotensin system and the endoplasmic reticulum stress in the cardiovascular system: Lessons learned so far.

Life sciences

Avec: Vinicius Sepúlveda-Fragoso , Beatriz Alexandre-Santos , Amanda Conceição Pimenta Salles , Ana Beatriz Proença , Ana Paula de Paula Alves , Manuel Vázquez-Carrera , Antonio Claudio Lucas Nóbrega , Eliete Dalla Corte Frantz , D'Angelo Carlo Magliano

Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy.

Trends in molecular medicine

Avec: Xavier Palomer , David Aguilar-Recarte , Raquel García , J Francisco Nistal , Manuel Vázquez-Carrera

Uncovering the role of apolipoprotein C-III in insulin resistance.

Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis

Avec: David Aguilar-Recarte , Xavier Palomer , Manuel Vázquez-Carrera

GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.

Cell reports

Avec: David Aguilar-Recarte , Emma Barroso , Anna Gumà , Javier Pizarro-Delgado , Lucía Peña , Maria Ruart , Xavier Palomer , Walter Wahli , Manuel Vázquez-Carrera

Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.

Trends in endocrinology and metabolism: TEM

Avec: David Aguilar-Recarte , Emma Barroso , Xavier Palomer , Walter Wahli , Manuel Vázquez-Carrera

Striking a gut-liver balance for the antidiabetic effects of metformin.

Trends in pharmacological sciences

Avec: Emma Barroso , Marta Montori-Grau , Walter Wahli , Xavier Palomer , Manuel Vázquez-Carrera

Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Meijian Zhang , Emma Barroso , Maria Ruart , Lucía Peña , Mona Peyman , David Aguilar-Recarte , Marta Montori-Grau , Patricia Rada , Clara Cugat , Carla Montironi , Mohammad Zarei , Javier Jurado-Aguilar , Antoni Camins , Jesús Balsinde , Ángela M Valverde , Walter Wahli , Xavier Palomer , Manuel Vázquez-Carrera

PPARβ/δ attenuates hepatic fibrosis by reducing SMAD3 phosphorylation and p300 levels via AMPK in hepatic stellate cells.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Meijian Zhang , Emma Barroso , Lucía Peña , Patricia Rada , Ángela M Valverde , Walter Wahli , Xavier Palomer , Manuel Vázquez-Carrera

Réseau de co-auteurs

Xavier Palomer 23 collaborations

Emma Barroso 19 collaborations

Walter Wahli 13 collaborations

David Aguilar-Recarte 10 collaborations

Javier Pizarro-Delgado 8 collaborations

Mohammad Zarei 7 collaborations

Meijian Zhang 6 collaborations

Mona Peyman 5 collaborations

Santiago Vázquez 5 collaborations

Patricia Rada 5 collaborations

Ángela M Valverde 5 collaborations

Javier Jurado-Aguilar 5 collaborations

Francesc Villarroya 4 collaborations

Lucía Peña 4 collaborations

Rosalía Rodríguez-Rodríguez 3 collaborations

Christian Griñán-Ferré 3 collaborations

Mercè Pallàs 3 collaborations

Antoni Camins 3 collaborations

Marta Montori-Grau 3 collaborations

Anna Planavila 2 collaborations

Christophe Morisseau 2 collaborations

Bruce D Hammock 2 collaborations

Vinicius Sepúlveda-Fragoso 2 collaborations

Beatriz Alexandre-Santos 2 collaborations

Eliete Dalla Corte Frantz 2 collaborations

D'Angelo Carlo Magliano 2 collaborations

Oriol Busquets 2 collaborations

Miren Ettcheto 2 collaborations

Ester Verdaguer 2 collaborations

Jordi Olloquequi 2 collaborations

Carme Auladell 2 collaborations

Jaume Folch 2 collaborations

Jesús Balsinde 2 collaborations

J Francisco Nistal 2 collaborations

Raquel García 2 collaborations

Maria Ruart 2 collaborations

Joan Carles Escolà-Gil 1 collaboration

Lidia Cedó 1 collaboration

Ricardo Rodríguez-Calvo 1 collaboration

Josefa Girona 1 collaboration

Marina Rodríguez 1 collaboration

Sara Samino 1 collaboration

David de Gonzalo-Calvo 1 collaboration

Sandra Guaita-Esteruelas 1 collaboration

Mercedes Heras 1 collaboration

Rutger W van der Meer 1 collaboration

Hildo J Lamb 1 collaboration

Oscar Yanes 1 collaboration

Xavier Correig 1 collaboration

Vicenta Llorente-Cortés 1 collaboration

Lluis Masana 1 collaboration

Anna Babin-Ebell 1 collaboration

Matilde Rigon 1 collaboration

Joan Villarroya 1 collaboration

Sandra Codony 1 collaboration

Carla Calvó-Tusell 1 collaboration

Elena Valverde 1 collaboration

Sílvia Osuna 1 collaboration

M Isabel Loza 1 collaboration

José Brea 1 collaboration

Concepción Pérez 1 collaboration

María Isabel Rodríguez-Franco 1 collaboration

Rubén Corpas 1 collaboration

Coral Sanfeliu 1 collaboration

Ferran Feixas 1 collaboration

Emanuelle Barreto-Reis 1 collaboration

Tiago Fernandes 1 collaboration

Edilamar Menezes Oliveira 1 collaboration

Soraia das Neves Vieira Cavalcanti 1 collaboration

Georgia Correa Atella 1 collaboration

Leandro Miranda-Alves 1 collaboration

Antonio Claudio Lucas da Nóbrega 1 collaboration

Maribel Bernard 1 collaboration

Àuria Eritja 1 collaboration

Blanca M López 1 collaboration

Patricia R Manzine 1 collaboration

Rubén D Castro-Torres 1 collaboration

Eugènia Pujol 1 collaboration

Tania Quesada-López 1 collaboration

Andrea Bagán 1 collaboration

Donna Martínez 1 collaboration

Carmen Escolano 1 collaboration

Jesús M Salvador 1 collaboration

Marta Díaz 1 collaboration

Ana Cristina Reguera 1 collaboration

Adel Rostami 1 collaboration

Lourdes Ibáñez 1 collaboration

Javier Pizarro-Degado 1 collaboration

Ester Sala 1 collaboration

Celia Vived 1 collaboration

Júlia Luna 1 collaboration

Noemí Alejandra Saavedra-Ávila 1 collaboration

Upasana Sengupta 1 collaboration

A Raúl Castaño 1 collaboration

Sabrina Villar-Pazos 1 collaboration

Laura Haba 1 collaboration

Joan Verdaguer 1 collaboration

Ana B Ropero 1 collaboration

Thomas Stratmann 1 collaboration

Javier Pizarro 1 collaboration

Angel Nadal 1 collaboration

Jill M Lahti 1 collaboration

Conchi Mora 1 collaboration

Andreea L Turcu 1 collaboration

Francesc Estrany 1 collaboration

Dáire Smith 1 collaboration

Carles Galdeano 1 collaboration

Triana Espinosa-Jiménez 1 collaboration

Amanda Cano 1 collaboration

Elena Sánchez-López 1 collaboration

Antoni Parcerisas 1 collaboration

Dolors Puigoriol-Illamola 1 collaboration

Rosana Leiva 1 collaboration

Manel Vázquez-Carrera 1 collaboration

Augusto Márquez 1 collaboration

Joan Aymerich 1 collaboration

Michele Dei 1 collaboration

Pablo Giménez-Gómez 1 collaboration

Ángel Merlos 1 collaboration

Lluís Terés 1 collaboration

Francesc Serra-Graells 1 collaboration

Cecilia Jiménez-Jorquera 1 collaboration

Carlos Domínguez 1 collaboration

Xavier Muñoz-Berbel 1 collaboration

M Silvia Román-Azcona 1 collaboration

Ana Planavila 1 collaboration

Brenda Valenzuela-Alcaraz 1 collaboration

Fátima Crispi 1 collaboration

Álvaro Sepúlveda-Martínez 1 collaboration

Irene Miguel-Escalada 1 collaboration

Jorge Ferrer 1 collaboration

Mercy M Davidson 1 collaboration

Amanda Conceição Pimenta Salles 1 collaboration

Ana Beatriz Proença 1 collaboration

Ana Paula de Paula Alves 1 collaboration

Antonio Claudio Lucas Nóbrega 1 collaboration

Anna Gumà 1 collaboration

Clara Cugat 1 collaboration

Carla Montironi 1 collaboration