Malaka Ameratunga

Affiliations

Drug Development Unit, Royal Marsden Hospital/Institute of Cancer Research, Sutton, UK.

Publications (14)

Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors.

Journal for immunotherapy of cancer

Avec: Dionysis Papadatos-Pastos , Wei Yuan , Abhijit Pal , Mateus Crespo , Ana Ferreira , Bora Gurel , Toby Prout , Malaka Ameratunga , Maxime Chénard-Poirier , Andra Curcean , Claudia Bertan , Chloe Baker , Susana Miranda , Nahal Masrour , Wentin Chen , Rita Pereira , Ines Figueiredo , Ricardo Morilla , Ben Jenkins , Anna Zachariou , Ruth Riisnaes , Mona Parmar , Alison Turner , Suzanne Carreira , Christina Yap , Robert Brown , Nina Tunariu , Udai Banerji , Juanita Lopez , Johann de Bono , Anna Minchom

UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma.

Oncogene

Avec: Gamze Kuser-Abali , Youfang Zhang , Pacman Szeto , Peinan Zhao , Samar Masoumi-Moghaddam , Clare G Fedele , Isobel Leece , Cheng Huang , Jen G Cheung , Malaka Ameratunga , Fumihito Noguchi , Miles C Andrews , Nicholas C Wong , Ralf B Schittenhelm , Mark Shackleton

Radiological Patterns of Drug-induced Interstitial Lung Disease (DILD) in Early-phase Oncology Clinical Trials.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Angelika Terbuch , Crescens Tiu , Irene Moreno Candilejo , Mariana Scaranti , Andra Curcean , Dan Bar , Miriam Estevez Timon , Malaka Ameratunga , Joo Ern Ang , Jonathan Ratoff , Anna R Minchom , Udai Banerji , Johann S de Bono , Nina Tunariu , Juanita S Lopez

To Cycle or Fight-CDK4/6 Inhibitors at the Crossroads of Anticancer Immunity.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Malaka Ameratunga , Emma Kipps , Alicia F C Okines , Juanita S Lopez

Symptomatic brain metastases in melanoma.

Experimental dermatology

Avec: Andrea Knox , Tim Wang , Mark Shackleton , Malaka Ameratunga

A systematic review of the impact of brain tumours on risk of motor vehicle crashes.

Journal of neuro-oncology

Avec: Sophie Tran , Adam Lapidus , Andrew Neal , Katherine B Peters , Lucy Gately , Malaka Ameratunga

First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours.

British journal of cancer

Avec: Malaka Ameratunga , Irene Braña , Petri Bono , Sophie Postel-Vinay , Ruth Plummer , John Aspegren , Timo Korjamo , Amir Snapir , Johann S de Bono

Globe Salvage and Vision Preservation by Neoadjuvant Darovasertib and Crizotinib in Uveal Melanoma.

Ophthalmology. Retina

Avec: Alison Hiong , Roderick O'Day , Lotte S Fog , Daniel McKay , John McKenzie , Malaka Ameratunga , Anthony M Joshua , Mark Shackleton

Sustained Clinical Response to Immunotherapy Followed by BET Inhibitor in a Patient with Unresectable Sinonasal NUT Carcinoma.

Journal of immunotherapy and precision oncology

Avec: Harriet Herbison , Sidney Davis , David Nickless , Andrew Haydon , Malaka Ameratunga

The kinase polypharmacology landscape of clinical PARP inhibitors.

Scientific reports

Avec: Albert A Antolin , Malaka Ameratunga , Udai Banerji , Paul A Clarke , Paul Workman , Bissan Al-Lazikani

Combination of BRAF and MEK inhibition in BRAF V600E mutant low-grade ganglioglioma.

Journal of clinical pharmacy and therapeutics

Avec: Wing Hing Yau , Malaka Ameratunga

Dramatic clinical response in the treatment of small cell glioblastoma multiforme.

Journal of clinical pharmacy and therapeutics

Avec: Farzana Yasmin Zaman , Catriona McLean , Malaka Ameratunga

A phase 1 safety and bioimaging trial of antibody DS-8895a against EphA2 in patients with advanced or metastatic EphA2 positive cancers.

Investigational new drugs

Avec: Hui K Gan , Sagun Parakh , F T Lee , Niall C Tebbutt , Malaka Ameratunga , Sze Ting Lee , Graeme J O'Keefe , Sylvia J Gong , Christine Vanrenen , Jaren Caine , Mara Giovannetti , Carmel Murone , Fiona E Scott , Nancy Guo , Ingrid J G Burvenich , Cameron Paine , Mary J Macri , Masakatsu Kotsuma , Giorgio Senaldi , Ralph Venhaus , Andrew M Scott

Computational repurposing of oncology drugs through off-target drug binding interactions from pharmacological databases.

Clinical and translational medicine

Avec: Imogen R Walpole , Farzana Y Zaman , Peinan Zhao , Vikki M Marshall , Frank P Lin , David M Thomas , Mark Shackleton , Albert A Antolin , Malaka Ameratunga

Réseau de co-auteurs

Mark Shackleton 4 collaborations

Udai Banerji 3 collaborations

Andra Curcean 2 collaborations

Nina Tunariu 2 collaborations

Peinan Zhao 2 collaborations

Johann S de Bono 2 collaborations

Juanita S Lopez 2 collaborations

Albert A Antolin 2 collaborations

Dionysis Papadatos-Pastos 1 collaboration

Wei Yuan 1 collaboration

Abhijit Pal 1 collaboration

Mateus Crespo 1 collaboration

Ana Ferreira 1 collaboration

Bora Gurel 1 collaboration

Toby Prout 1 collaboration

Maxime Chénard-Poirier 1 collaboration

Claudia Bertan 1 collaboration

Chloe Baker 1 collaboration

Susana Miranda 1 collaboration

Nahal Masrour 1 collaboration

Wentin Chen 1 collaboration

Rita Pereira 1 collaboration

Ines Figueiredo 1 collaboration

Ricardo Morilla 1 collaboration

Ben Jenkins 1 collaboration

Anna Zachariou 1 collaboration

Ruth Riisnaes 1 collaboration

Mona Parmar 1 collaboration

Alison Turner 1 collaboration

Suzanne Carreira 1 collaboration

Christina Yap 1 collaboration

Robert Brown 1 collaboration

Juanita Lopez 1 collaboration

Johann de Bono 1 collaboration

Anna Minchom 1 collaboration

Gamze Kuser-Abali 1 collaboration

Youfang Zhang 1 collaboration

Pacman Szeto 1 collaboration

Samar Masoumi-Moghaddam 1 collaboration

Clare G Fedele 1 collaboration

Isobel Leece 1 collaboration

Cheng Huang 1 collaboration

Jen G Cheung 1 collaboration

Fumihito Noguchi 1 collaboration

Miles C Andrews 1 collaboration

Nicholas C Wong 1 collaboration

Ralf B Schittenhelm 1 collaboration

Angelika Terbuch 1 collaboration

Crescens Tiu 1 collaboration

Irene Moreno Candilejo 1 collaboration

Mariana Scaranti 1 collaboration

Dan Bar 1 collaboration

Miriam Estevez Timon 1 collaboration

Joo Ern Ang 1 collaboration

Jonathan Ratoff 1 collaboration

Anna R Minchom 1 collaboration

Emma Kipps 1 collaboration

Alicia F C Okines 1 collaboration

Andrea Knox 1 collaboration

Tim Wang 1 collaboration

Sophie Tran 1 collaboration

Adam Lapidus 1 collaboration

Andrew Neal 1 collaboration

Katherine B Peters 1 collaboration

Lucy Gately 1 collaboration

Irene Braña 1 collaboration

Petri Bono 1 collaboration

Sophie Postel-Vinay 1 collaboration

Ruth Plummer 1 collaboration

John Aspegren 1 collaboration

Timo Korjamo 1 collaboration

Amir Snapir 1 collaboration

Alison Hiong 1 collaboration

Roderick O'Day 1 collaboration

Lotte S Fog 1 collaboration

Daniel McKay 1 collaboration

John McKenzie 1 collaboration

Anthony M Joshua 1 collaboration

Harriet Herbison 1 collaboration

Sidney Davis 1 collaboration

David Nickless 1 collaboration

Andrew Haydon 1 collaboration

Paul A Clarke 1 collaboration

Paul Workman 1 collaboration

Bissan Al-Lazikani 1 collaboration

Wing Hing Yau 1 collaboration

Farzana Yasmin Zaman 1 collaboration

Catriona McLean 1 collaboration

Hui K Gan 1 collaboration

Sagun Parakh 1 collaboration

F T Lee 1 collaboration

Niall C Tebbutt 1 collaboration

Sze Ting Lee 1 collaboration

Graeme J O'Keefe 1 collaboration

Sylvia J Gong 1 collaboration

Christine Vanrenen 1 collaboration

Jaren Caine 1 collaboration

Mara Giovannetti 1 collaboration

Carmel Murone 1 collaboration

Fiona E Scott 1 collaboration

Nancy Guo 1 collaboration

Ingrid J G Burvenich 1 collaboration

Cameron Paine 1 collaboration

Mary J Macri 1 collaboration

Masakatsu Kotsuma 1 collaboration

Giorgio Senaldi 1 collaboration

Ralph Venhaus 1 collaboration

Andrew M Scott 1 collaboration

Imogen R Walpole 1 collaboration

Farzana Y Zaman 1 collaboration

Vikki M Marshall 1 collaboration

Frank P Lin 1 collaboration

David M Thomas 1 collaboration