Lucy Ghoda

Affiliations

Hematology Malignancies and Stem Cell Transplantation Institute, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, California.

Publications (17)

8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia.

Journal of cellular physiology

Avec: Ralf Buettner , Le Xuan Truong Nguyen , Bijender Kumar , Corey Morales , Chao Liu , Lisa S Chen , Tea Pemovska , Timothy W Synold , Joycelynne Palmer , Ryan Thompson , Ling Li , Dinh Hoa Hoang , Bin Zhang , Lucy Ghoda , Claudia Kowolik , Mika Kontro , Calum Leitch , Krister Wennerberg , Xiaochun Yu , Ching-Cheng Chen , David Horne , Varsha Gandhi , Vinod Pullarkat , Guido Marcucci , Steven T Rosen

Leveraging IFNγ/CD38 regulation to unmask and target leukemia stem cells in acute myelogenous leukemia.

bioRxiv : the preprint server for biology

Avec: Mariam Murtadha , Miso Park , Yinghui Zhu , Enrico Caserta , Ada Alice Dona , Mahmoud Singer , Hawa Vahed , Theophilus Tasndoh , Asaul Gonzalez , Kevin Ly , James F Sanchez , Arnab Chowdhury , Alex Pozhitkov , Lucy Ghoda , Ling Li , Bin Zhang , Amrita Krishnan , Guido Marcucci , John Williams , Flavia Pichiorri

Flotetuzumab as a salvage immunotherapy in advanced CD123-positive hematological malignancies, a phase 1 pilot study.

Leukemia & lymphoma

Avec: Ibrahim Aldoss , Jianying Zhang , Marjorie Robbins , Joo Song , Monzr M Al Malki , Salman Otoukesh , Karamjeet Sandhu , Vaibhav Agrawal , Alex F Herrera , Leslie L Popplewell , Lucy Ghoda , Anthony Stein , Guido Marcucci , Stephen Forman , Vinod Pullarkat

Ebp1 p48 promotes oncogenic activities in human colon cancer cells through regulation of TIF-90-mediated ribosomal RNA synthesis.

Journal of cellular physiology

Avec: Dang Quan Nguyen , Dinh Hoa Hoang , Thanh Thao Vo Nguyen , Huu Duc Ho , Vu Huynh , June Ho Shin , Quoc Trung Ly , Dai Dong Thi Nguyen , Lucy Ghoda , Guido Marcucci , Le Xuan Truong Nguyen

Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia.

Blood

Avec: Caroline Duault , Anil Kumar , Adeleh Taghi Khani , Sung June Lee , Lu Yang , Min Huang , Christian Hurtz , Bryan Manning , Lucy Ghoda , Tinisha McDonald , Norman J Lacayo , Kathleen M Sakamoto , Martin Carroll , Sarah K Tasian , Guido Marcucci , Jianhua Yu , Michael A Caligiuri , Holden T Maecker , Srividya Swaminathan

Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis.

Nature communications

Avec: Bin Zhang , Dandan Zhao , Fang Chen , David Frankhouser , Huafeng Wang , Khyatiben V Pathak , Lei Dong , Anakaren Torres , Krystine Garcia-Mansfield , Yi Zhang , Dinh Hoa Hoang , Min-Hsuan Chen , Shu Tao , Hyejin Cho , Yong Liang , Danilo Perrotti , Sergio Branciamore , Russell Rockne , Xiwei Wu , Lucy Ghoda , Ling Li , Jie Jin , Jianjun Chen , Jianhua Yu , Michael A Caligiuri , Ya-Huei Kuo , Mark Boldin , Rui Su , Piotr Swiderski , Marcin Kortylewski , Patrick Pirrotte , Le Xuan Truong Nguyen , Guido Marcucci

State-transition modeling of blood transcriptome predicts disease evolution and treatment response in chronic myeloid leukemia.

Leukemia

Avec: David E Frankhouser , Russell C Rockne , Lisa Uechi , Dandan Zhao , Sergio Branciamore , Denis O'Meally , Jihyun Irizarry , Lucy Ghoda , Haris Ali , Jeffery M Trent , Stephen Forman , Yu-Hsuan Fu , Ya-Huei Kuo , Bin Zhang , Guido Marcucci

Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.

Nature cancer

Avec: Haojie Dong , Xin He , Lei Zhang , Wei Chen , Yi-Chun Lin , Song-Bai Liu , Huafeng Wang , Le Xuan Truong Nguyen , Min Li , Yinghui Zhu , Dandan Zhao , Lucy Ghoda , Jonathan Serody , Benjamin Vincent , Leo Luznik , Ivana Gojo , Joshua Zeidner , Rui Su , Jianjun Chen , Ritin Sharma , Patrick Pirrotte , Xiwei Wu , Weidong Hu , Weidong Han , Binghui Shen , Ya-Huei Kuo , Jie Jin , Amandeep Salhotra , Jeffrey Wang , Guido Marcucci , Yun Lyna Luo , Ling Li

Spred1 deficit promotes treatment resistance and transformation of chronic phase CML.

Leukemia

Avec: Junjing Qiao , Chen Liang , Dandan Zhao , Le Xuan Truong Nguyen , Fang Chen , Shanshan Suo , Dinh Hoa Hoang , Francesca Pellicano , Ivan Rodriguez Rodriguez , Yasmin Elhajmoussa , Lucy Ghoda , Akihiko Yoshimura , Anthony S Stein , Haris Ali , Paul Koller , Danilo Perrotti , Mhairi Copland , Anjia Han , Bin Amber Zhang , Guido Marcucci

Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Lizhao Feng , Jianfei Chao , E Tian , Li Li , Peng Ye , Mi Zhang , Xianwei Chen , Qi Cui , Guihua Sun , Tao Zhou , Gerardo Felix , Yue Qin , Wendong Li , Edward David Meza , Jeremy Klein , Lucy Ghoda , Weidong Hu , Yonglun Luo , Wei Dang , David Hsu , Joseph Gold , Steven A Goldman , Reuben Matalon , Yanhong Shi

Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia.

Journal for immunotherapy of cancer

Avec: Anil Kumar , Adeleh Taghi Khani , Caroline Duault , Soraya Aramburo , Ashly Sanchez Ortiz , Sung June Lee , Anthony Chan , Tinisha McDonald , Min Huang , Norman J Lacayo , Kathleen M Sakamoto , Jianhua Yu , Christian Hurtz , Martin Carroll , Sarah K Tasian , Lucy Ghoda , Guido Marcucci , Zhaohui Gu , Steven T Rosen , Saro Armenian , Shai Izraeli , Chun-Wei Chen , Michael A Caligiuri , Stephen J Forman , Holden T Maecker , Srividya Swaminathan

State-transition Modeling of Blood Transcriptome Predicts Disease Evolution and Treatment Response in Chronic Myeloid Leukemia.

bioRxiv : the preprint server for biology

Avec: David E Frankhouser , Russell C Rockne , Lisa Uechi , Dandan Zhao , Sergio Branciamore , Denis O'Meally , Jihyun Irizarry , Lucy Ghoda , Haris Ali , Jeffrey Trent , Stephen Forman , Yu-Hsuan Fu , Ya-Huei Kuo , Bin Zhang , Guido Marcucci

The Bcl-2 inhibitor venetoclax inhibits Nrf2 antioxidant pathway activation induced by hypomethylating agents in AML.

Journal of cellular physiology

Avec: Le Xuan Truong Nguyen , Estelle Troadec , Arjun Kalvala , Bijender Kumar , Dinh Hoa Hoang , Domenico Viola , Bin Zhang , Dang Quan Nguyen , Ibrahim Aldoss , Lucy Ghoda , Elizabeth Budde , Flavia Pichiorri , Steven Rosen , Stephen J Forman , Guido Marcucci , Vinod Pullarkat

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting.

Leukemia

Avec: Domenico Viola , Ada Dona , Enrico Caserta , Estelle Troadec , Francesca Besi , Tinisha McDonald , Lucy Ghoda , Emine Gulsen Gunes , James F Sanchez , Jihane Khalife , Marianna Martella , Chatchada Karanes , Myo Htut , Xiuli Wang , Michael Rosenzweig , Arnab Chowdhury , Douglas Sborov , Rodney R Miles , Paul J Yazaki , Todd Ebner , Craig C Hofmeister , Stephen J Forman , Steven T Rosen , Guido Marcucci , John Shively , Jonathan J Keats , Amrita Krishnan , Flavia Pichiorri

Arsenic Trioxide and Venetoclax Synergize against AML Progenitors by ROS Induction and Inhibition of Nrf2 Activation.

International journal of molecular sciences

Avec: Dinh Hoa Hoang , Ralf Buettner , Melissa Valerio , Lucy Ghoda , Bin Zhang , Ya-Huei Kuo , Steven T Rosen , John Burnett , Guido Marcucci , Vinod Pullarkat , Le Xuan Truong Nguyen

Treatment-induced arteriolar revascularization and miR-126 enhancement in bone marrow niche protect leukemic stem cells in AML.

Journal of hematology & oncology

Avec: Bin Zhang , Le Xuan Truong Nguyen , Dandan Zhao , David E Frankhouser , Huafeng Wang , Dinh Hoa Hoang , Junjing Qiao , Christina Abundis , Matthew Brehove , Yu-Lin Su , Yuxin Feng , Anthony Stein , Lucy Ghoda , Adrianne Dorrance , Danilo Perrotti , Zhen Chen , Anjia Han , Flavia Pichiorri , Jie Jin , Tijana Jovanovic-Talisman , Michael A Caligiuri , Calvin J Kuo , Akihiko Yoshimura , Ling Li , Russell C Rockne , Marcin Kortylewski , Yi Zheng , Nadia Carlesso , Ya-Huei Kuo , Guido Marcucci

Homoharringtonine synergizes with venetoclax in early T cell progenitor acute lymphoblastic leukemia: Bench and bed.

Med (New York, N.Y.)

Avec: Shanshan Suo , Shu Sun , Le Xuan Truong Nguyen , Jiejing Qian , Fenglin Li , Dandan Zhao , Wenjuan Yu , Yinjun Lou , Honghu Zhu , Hongyan Tong , Min Yang , Xin Huang , Shuqi Zhao , Junjing Qiao , Chen Liang , Huafeng Wang , Yi Zhang , Xiang Zhang , Dinh Hoa Hoang , Fang Chen , Hyunjun Kang , Melissa Valerio , Jie Sun , Lucy Ghoda , Ling Li , Guido Marcucci , Bin Zhang , Jie Jin

Réseau de co-auteurs

Guido Marcucci 16 collaborations

Le Xuan Truong Nguyen 9 collaborations

Bin Zhang 9 collaborations

Dinh Hoa Hoang 8 collaborations

Dandan Zhao 7 collaborations

Ling Li 6 collaborations

Ya-Huei Kuo 6 collaborations

Vinod Pullarkat 4 collaborations

Steven T Rosen 4 collaborations

Flavia Pichiorri 4 collaborations

Michael A Caligiuri 4 collaborations

Huafeng Wang 4 collaborations

Jie Jin 4 collaborations

Stephen Forman 3 collaborations

Tinisha McDonald 3 collaborations

Jianhua Yu 3 collaborations

Fang Chen 3 collaborations

Danilo Perrotti 3 collaborations

Sergio Branciamore 3 collaborations

David E Frankhouser 3 collaborations

Russell C Rockne 3 collaborations

Haris Ali 3 collaborations

Junjing Qiao 3 collaborations

Stephen J Forman 3 collaborations

Ralf Buettner 2 collaborations

Bijender Kumar 2 collaborations

Yinghui Zhu 2 collaborations

Enrico Caserta 2 collaborations

James F Sanchez 2 collaborations

Arnab Chowdhury 2 collaborations

Amrita Krishnan 2 collaborations

Ibrahim Aldoss 2 collaborations

Anthony Stein 2 collaborations

Dang Quan Nguyen 2 collaborations

Caroline Duault 2 collaborations

Anil Kumar 2 collaborations

Adeleh Taghi Khani 2 collaborations

Sung June Lee 2 collaborations

Min Huang 2 collaborations

Christian Hurtz 2 collaborations

Norman J Lacayo 2 collaborations

Kathleen M Sakamoto 2 collaborations

Martin Carroll 2 collaborations

Sarah K Tasian 2 collaborations

Holden T Maecker 2 collaborations

Srividya Swaminathan 2 collaborations

Yi Zhang 2 collaborations

Xiwei Wu 2 collaborations

Jianjun Chen 2 collaborations

Rui Su 2 collaborations

Marcin Kortylewski 2 collaborations

Patrick Pirrotte 2 collaborations

Lisa Uechi 2 collaborations

Denis O'Meally 2 collaborations

Jihyun Irizarry 2 collaborations

Yu-Hsuan Fu 2 collaborations

Weidong Hu 2 collaborations

Chen Liang 2 collaborations

Shanshan Suo 2 collaborations

Akihiko Yoshimura 2 collaborations

Anjia Han 2 collaborations

Estelle Troadec 2 collaborations

Domenico Viola 2 collaborations

Melissa Valerio 2 collaborations

Corey Morales 1 collaboration

Chao Liu 1 collaboration

Lisa S Chen 1 collaboration

Tea Pemovska 1 collaboration

Timothy W Synold 1 collaboration

Joycelynne Palmer 1 collaboration

Ryan Thompson 1 collaboration

Claudia Kowolik 1 collaboration

Mika Kontro 1 collaboration

Calum Leitch 1 collaboration

Krister Wennerberg 1 collaboration

Xiaochun Yu 1 collaboration

Ching-Cheng Chen 1 collaboration

David Horne 1 collaboration

Varsha Gandhi 1 collaboration

Mariam Murtadha 1 collaboration

Miso Park 1 collaboration

Ada Alice Dona 1 collaboration

Mahmoud Singer 1 collaboration

Hawa Vahed 1 collaboration

Theophilus Tasndoh 1 collaboration

Asaul Gonzalez 1 collaboration

Kevin Ly 1 collaboration

Alex Pozhitkov 1 collaboration

John Williams 1 collaboration

Jianying Zhang 1 collaboration

Marjorie Robbins 1 collaboration

Joo Song 1 collaboration

Monzr M Al Malki 1 collaboration

Salman Otoukesh 1 collaboration

Karamjeet Sandhu 1 collaboration

Vaibhav Agrawal 1 collaboration

Alex F Herrera 1 collaboration

Leslie L Popplewell 1 collaboration

Thanh Thao Vo Nguyen 1 collaboration

Huu Duc Ho 1 collaboration

Vu Huynh 1 collaboration

June Ho Shin 1 collaboration

Quoc Trung Ly 1 collaboration

Dai Dong Thi Nguyen 1 collaboration

Lu Yang 1 collaboration

Bryan Manning 1 collaboration

David Frankhouser 1 collaboration

Khyatiben V Pathak 1 collaboration

Lei Dong 1 collaboration

Anakaren Torres 1 collaboration

Krystine Garcia-Mansfield 1 collaboration

Min-Hsuan Chen 1 collaboration

Shu Tao 1 collaboration

Hyejin Cho 1 collaboration

Yong Liang 1 collaboration

Russell Rockne 1 collaboration

Mark Boldin 1 collaboration

Piotr Swiderski 1 collaboration

Jeffery M Trent 1 collaboration

Haojie Dong 1 collaboration

Xin He 1 collaboration

Lei Zhang 1 collaboration

Wei Chen 1 collaboration

Yi-Chun Lin 1 collaboration

Song-Bai Liu 1 collaboration

Min Li 1 collaboration

Jonathan Serody 1 collaboration

Benjamin Vincent 1 collaboration

Leo Luznik 1 collaboration

Ivana Gojo 1 collaboration

Joshua Zeidner 1 collaboration

Ritin Sharma 1 collaboration

Weidong Han 1 collaboration

Binghui Shen 1 collaboration

Amandeep Salhotra 1 collaboration

Jeffrey Wang 1 collaboration

Yun Lyna Luo 1 collaboration

Francesca Pellicano 1 collaboration

Ivan Rodriguez Rodriguez 1 collaboration

Yasmin Elhajmoussa 1 collaboration

Anthony S Stein 1 collaboration

Paul Koller 1 collaboration

Mhairi Copland 1 collaboration

Bin Amber Zhang 1 collaboration

Lizhao Feng 1 collaboration

Jianfei Chao 1 collaboration

E Tian 1 collaboration

Li Li 1 collaboration

Peng Ye 1 collaboration

Mi Zhang 1 collaboration

Xianwei Chen 1 collaboration

Qi Cui 1 collaboration

Guihua Sun 1 collaboration

Tao Zhou 1 collaboration

Gerardo Felix 1 collaboration

Yue Qin 1 collaboration

Wendong Li 1 collaboration

Edward David Meza 1 collaboration

Jeremy Klein 1 collaboration

Yonglun Luo 1 collaboration

Wei Dang 1 collaboration

David Hsu 1 collaboration

Joseph Gold 1 collaboration

Steven A Goldman 1 collaboration

Reuben Matalon 1 collaboration

Yanhong Shi 1 collaboration

Soraya Aramburo 1 collaboration

Ashly Sanchez Ortiz 1 collaboration

Anthony Chan 1 collaboration

Zhaohui Gu 1 collaboration

Saro Armenian 1 collaboration

Shai Izraeli 1 collaboration

Chun-Wei Chen 1 collaboration

Jeffrey Trent 1 collaboration

Arjun Kalvala 1 collaboration

Elizabeth Budde 1 collaboration

Steven Rosen 1 collaboration

Ada Dona 1 collaboration

Francesca Besi 1 collaboration

Emine Gulsen Gunes 1 collaboration

Jihane Khalife 1 collaboration

Marianna Martella 1 collaboration

Chatchada Karanes 1 collaboration

Myo Htut 1 collaboration

Xiuli Wang 1 collaboration

Michael Rosenzweig 1 collaboration

Douglas Sborov 1 collaboration

Rodney R Miles 1 collaboration

Paul J Yazaki 1 collaboration

Todd Ebner 1 collaboration

Craig C Hofmeister 1 collaboration

John Shively 1 collaboration

Jonathan J Keats 1 collaboration

John Burnett 1 collaboration

Christina Abundis 1 collaboration

Matthew Brehove 1 collaboration

Yu-Lin Su 1 collaboration

Yuxin Feng 1 collaboration

Adrianne Dorrance 1 collaboration

Zhen Chen 1 collaboration

Tijana Jovanovic-Talisman 1 collaboration

Calvin J Kuo 1 collaboration

Yi Zheng 1 collaboration

Nadia Carlesso 1 collaboration

Shu Sun 1 collaboration

Jiejing Qian 1 collaboration

Fenglin Li 1 collaboration

Wenjuan Yu 1 collaboration

Yinjun Lou 1 collaboration

Honghu Zhu 1 collaboration

Hongyan Tong 1 collaboration

Min Yang 1 collaboration

Xin Huang 1 collaboration

Shuqi Zhao 1 collaboration

Xiang Zhang 1 collaboration

Hyunjun Kang 1 collaboration

Jie Sun 1 collaboration