Luca Dellafiora

Affiliations

Department of Food and Drug, University of Parma, Area Parco delle Scienze 27/A, 43124, Parma, Italy.

ORCID: https://orcid.org/0000-0002-1901-3317

Publications (50)

Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study.

Archives of toxicology

Avec: Georg Aichinger , Luca Dellafiora , Foteini Pantazi , Giorgia Del Favero , Gianni Galaverna , Chiara Dall'Asta , Doris Marko

An in silico structural approach to characterize human and rainbow trout estrogenicity of mycotoxins: Proof of concept study using zearalenone and alternariol.

Food chemistry

Avec: Luca Dellafiora , Isabelle P Oswald , Jean-Lou Dorne , Gianni Galaverna , Paola Battilani , Chiara Dall'Asta

"Bottom-Up" Strategy for the Identification of Novel Soybean Peptides with Angiotensin-Converting Enzyme Inhibitory Activity.

Journal of agricultural and food chemistry

Avec: Luca Dellafiora , Raffaele Pugliese , Carlotta Bollati , Fabrizio Gelain , Gianni Galaverna , Anna Arnoldi , Carmen Lammi

A target fishing study to spot possible biological targets of fusaric acid: Inhibition of protein kinase-A and insights on the underpinning mechanisms.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Avec: Giorgia Del Favero , Georg Aichinger , Julia Hohenbichler , Doris Marko , Chiara Dall'Asta , Luca Dellafiora

Cleaning the Label of Cured Meat; Effect of the Replacement of Nitrates/Nitrites on Nutrients Bioaccessibility, Peptides Formation, and Cellular Toxicity of In Vitro Digested Salami.

International journal of molecular sciences

Avec: Mattia Di Nunzio , Cecilia Loffi , Serena Montalbano , Elena Chiarello , Luca Dellafiora , Gianfranco Picone , Giorgia Antonelli , Tullia Tedeschi , Annamaria Buschini , Francesco Capozzi , Gianni Galaverna , Alessandra Bordoni

Experimental-theoretical study of laccase as a detoxifier of aflatoxins.

Scientific reports

Avec: Marco Zaccaria , William Dawson , Darius Russel Kish , Massimo Reverberi , Maria Carmela Bonaccorsi di Patti , Marek Domin , Viviana Cristiglio , Bun Chan , Luca Dellafiora , Frank Gabel , Takahito Nakajima , Luigi Genovese , Babak Momeni

Free fatty acid receptors beyond fatty acids: A computational journey to explore peptides as possible binders of GPR120.

Current research in food science

Avec: Lorenzo Pedroni , Florinda Perugino , Fabio Magnaghi , Chiara Dall'Asta , Gianni Galaverna , Luca Dellafiora

A computational study toward the "personalized" activity of alternariol - Does it matter for safe food at individual level?

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Avec: Luca Dellafiora , Gianni Galaverna , Gabriele Cruciani , Chiara Dall'Asta

Hybrid in silico/in vitro target fishing to assign function to "orphan" compounds of food origin - The case of the fungal metabolite atromentin.

Food chemistry

Avec: Luca Dellafiora , Georg Aichinger , Elena Geib , Leyre Sánchez-Barrionuevo , Matthias Brock , David Cánovas , Chiara Dall'Asta , Doris Marko

Co-Occurrence and Combinatory Effects of

Toxins

Avec: Francesco Crudo , Elisabeth Varga , Georg Aichinger , Gianni Galaverna , Doris Marko , Chiara Dall'Asta , Luca Dellafiora

Simulated Gastrointestinal Digestion of Cocoa: Detection of Resistant Peptides and In Silico/In Vitro Prediction of Their Ace Inhibitory Activity.

Nutrients

Avec: Angela Marseglia , Luca Dellafiora , Barbara Prandi , Veronica Lolli , Stefano Sforza , Pietro Cozzini , Tullia Tedeschi , Gianni Galaverna , Augusta Caligiani

Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4).

Archives of toxicology

Avec: Jochem Louisse , Luca Dellafiora , Jeroen J M W van den Heuvel , Deborah Rijkers , Liz Leenders , Jean-Lou C M Dorne , Ans Punt , Frans G M Russel , Jan B Koenderink

A mechanistic toxicology study to grasp the mechanics of zearalenone estrogenicity: Spotlighting aromatase and the effects of its genetic variability.

Toxicology

Avec: Florinda Perugino , Lorenzo Pedroni , Gianni Galaverna , Chiara Dall'Asta , Luca Dellafiora

Computational methods meet in vitro techniques: A case study on fusaric acid and its possible detoxification through cytochrome P450 enzymes.

Ecotoxicology and environmental safety

Avec: Lorenzo Pedroni , Daniel Zocchi Doherty , Chiara Dall'Asta , Gianni Galaverna , Stephen G Bell , Luca Dellafiora

In vitro and in silico characterization of the transport of selected perfluoroalkyl carboxylic acids and perfluoroalkyl sulfonic acids by human organic anion transporter 1 (OAT1), OAT2 and OAT3.

Toxicology

Avec: Jochem Louisse , Lorenzo Pedroni , Jeroen J M W van den Heuvel , Deborah Rijkers , Liz Leenders , Annelies Noorlander , Ans Punt , Frans G M Russel , Jan B Koenderink , Luca Dellafiora

Interaction of Mycotoxin Alternariol with Serum Albumin.

International journal of molecular sciences

Avec: Eszter Fliszár-Nyúl , Beáta Lemli , Sándor Kunsági-Máté , Luca Dellafiora , Chiara Dall'Asta , Gabriele Cruciani , Gábor Pethő , Miklós Poór

Modulation of aflatoxin B1 cytotoxicity and aflatoxin M1 synthesis by natural antioxidants in a bovine mammary epithelial cell line.

Toxicology in vitro : an international journal published in association with BIBRA

Avec: Shiva Ghadiri , Veronica Spalenza , Luca Dellafiora , Paola Badino , Andrea Barbarossa , Chiara Dall'Asta , Carlo Nebbia , Flavia Girolami

Assessment of the Multifunctional Behavior of Lupin Peptide P7 and Its Metabolite Using an Integrated Strategy.

Journal of agricultural and food chemistry

Avec: Carmen Lammi , Gilda Aiello , Luca Dellafiora , Carlotta Bollati , Giovanna Boschin , Giulia Ranaldi , Simonetta Ferruzza , Yula Sambuy , Gianni Galaverna , Anna Arnoldi

Persistence of the antagonistic effects of a natural mixture of Alternaria mycotoxins on the estrogen-like activity of human feces after anaerobic incubation.

Toxicology letters

Avec: Francesco Crudo , Georg Aichinger , Luca Dellafiora , Endre Kiss , Jovana Mihajlovic , Giorgia Del Favero , David Berry , Chiara Dall'Asta , Doris Marko

An In Silico Framework to Mine Bioactive Peptides from Annotated Proteomes: A Case Study on Pancreatic Alpha Amylase Inhibitory Peptides from Algae and Cyanobacteria.

Nutrients

Avec: Lorenzo Pedroni , Florinda Perugino , Gianni Galaverna , Chiara Dall'Asta , Luca Dellafiora

Sprouts of

Molecules (Basel, Switzerland)

Avec: Martina Cirlini , Lorenzo Del Vecchio , Leandra Leto , Federica Russo , Luca Dellafiora , Valeria Guarrasi , Benedetta Chiancone

A computational study on the biotransformation of alkenylbenzenes by a selection of CYPs: Reflections on their possible bioactivation.

Toxicology

Avec: Lorenzo Pedroni , Jochem Louisse , Jean-Lou C M Dorne , Chiara Dall'Asta , Luca Dellafiora

The Occurrence of Non-Regulated Mycotoxins in Foods: A Systematic Review.

Toxins

Avec: Octavian Augustin Mihalache , Marthe De Boevre , Luca Dellafiora , Sarah De Saeger , Antonio Moretti , Laetitia Pinson-Gadais , Nadia Ponts , Florence Richard-Forget , Antonia Susca , Chiara Dall'Asta

Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol.

Cells

Avec: Giorgia Del Favero , Raphaela M Mayer , Luca Dellafiora , Lukas Janker , Laura Niederstaetter , Chiara Dall'Asta , Christopher Gerner , Doris Marko

An In Silico Target Fishing Approach to Identify Novel Ochratoxin A Hydrolyzing Enzyme.

Toxins

Avec: Luca Dellafiora , Christoph Gonaus , Barbara Streit , Gianni Galaverna , Wulf-Dieter Moll , Gudrun Vogtentanz , Gerd Schatzmayr , Chiara Dall'Asta , Shreenath Prasad

Investigating the interaction between organic anion transporter 1 and ochratoxin A: An in silico structural study to depict early molecular events of substrate recruitment and the impact of single point mutations.

Toxicology letters

Avec: Jochem Louisse , Jean Lou C M Dorne , Luca Dellafiora

Thinking Out of the Box: On the Ability of

Frontiers in plant science

Avec: Laura Righetti , Enrico Rolli , Luca Dellafiora , Gianni Galaverna , Michele Suman , Renato Bruni , Chiara Dall'Asta

An in silico insight on the mechanistic aspects of gelsenicine toxicity: A reverse screening study pointing to the possible involvement of acetylcholine binding receptor.

Toxicology letters

Avec: Lorenzo Pedroni , Jean Lou C M Dorne , Chiara Dall'Asta , Luca Dellafiora

Multi-tissue proteogenomic analysis for mechanistic toxicology studies in non-model species.

Environment international

Avec: M S Lin , M S Varunjikar , K K Lie , L Søfteland , L Dellafiora , R Ørnsrud , M Sanden , M H G Berntssen , J L C M Dorne , V Bafna , J D Rasinger

Mechanistic Insights into Angiotensin I-Converting Enzyme Inhibitory Tripeptides to Decipher the Chemical Basis of Their Activity.

Journal of agricultural and food chemistry

Avec: Carmen Lammi , Giovanna Boschin , Martina Bartolomei , Anna Arnoldi , Gianni Galaverna , Luca Dellafiora

A Computational Inter-Species Study on Safrole Phase I Metabolism-Dependent Bioactivation: A Mechanistic Insight into the Study of Possible Differences among Species.

Toxins

Avec: Lorenzo Pedroni , Jochem Louisse , Ans Punt , Jean Lou C M Dorne , Chiara Dall'Asta , Luca Dellafiora

Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways.

Toxicology letters

Avec: Francesco Crudo , Luca Dellafiora , Chenyifan Hong , Lena Burger , Maximilian Jobst , Giorgia Del Favero , Doris Marko

Molecular Characterization of the Allergenic Arginine Kinase from the Edible Insect Hermetia illucens (Black Soldier Fly).

Molecular nutrition & food research

Avec: Danila Delfino , Barbara Prandi , Luisa Calcinai , Erminia Ridolo , Luca Dellafiora , Lorenzo Pedroni , Francesca Nicoletta , Davide Cavazzini , Tullia Tedeschi , Claudia Folli

Virtual display of targets: A new level to rise the current understanding of ochratoxin A toxicity from a molecular standpoint.

Toxicology

Avec: Florinda Perugino , Lorenzo Pedroni , Gianni Galaverna , Chiara Dall'Asta , Luca Dellafiora

Gut microbiota and undigested food constituents modify toxin composition and suppress the genotoxicity of a naturally occurring mixture of Alternaria toxins in vitro.

Archives of toxicology

Avec: Francesco Crudo , Georg Aichinger , Jovana Mihajlovic , Luca Dellafiora , Elisabeth Varga , Hannes Puntscher , Benedikt Warth , Chiara Dall'Asta , David Berry , Doris Marko

A Hybrid In Silico/In Vitro Target Fishing Study to Mine Novel Targets of Urolithin A and B: A Step Towards a Better Comprehension of Their Estrogenicity.

Molecular nutrition & food research

Avec: Luca Dellafiora , Marco Milioli , Angela Falco , Margherita Interlandi , Abdelrahman Mohamed , Martin Frotscher , Benedetta Riccardi , Paola Puccini , Daniele Del Rio , Gianni Galaverna , Chiara Dall'Asta

Cyclodextrins Can Entrap Zearalenone-14-Glucoside: Interaction of the Masked Mycotoxin with Cyclodextrins and Cyclodextrin Bead Polymer.

Biomolecules

Avec: Zelma Faisal , Eszter Fliszár-Nyúl , Luca Dellafiora , Gianni Galaverna , Chiara Dall'Asta , Beáta Lemli , Sándor Kunsági-Máté , Lajos Szente , Miklós Poór

In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship.

Archives of toxicology

Avec: Francesco Crudo , Georg Aichinger , Jovana Mihajlovic , Elisabeth Varga , Luca Dellafiora , Benedikt Warth , Chiara Dall'Asta , David Berry , Doris Marko

An in vitro study on the transport and phase II metabolism of the mycotoxin alternariol in combination with the structurally related gut microbial metabolite urolithin C.

Toxicology letters

Avec: Francesco Crudo , Amelia Barilli , Pedro Mena , Bianca Maria Rotoli , Daniele Del Rio , Chiara Dall'Asta , Luca Dellafiora

A heuristic, computer-driven and top-down approach to identify novel bioactive peptides: A proof-of-principle on angiotensin I converting enzyme inhibitory peptides.

Food research international (Ottawa, Ont.)

Avec: Carmen Lammi , Giovanna Boschin , Carlotta Bollati , Anna Arnoldi , Gianni Galaverna , Luca Dellafiora

Impact of a Shorter Brine Soaking Time on Nutrient Bioaccessibility and Peptide Formation in 30-Months-Ripened Parmigiano Reggiano Cheese.

Molecules (Basel, Switzerland)

Avec: Mattia Di Nunzio , Cecilia Loffi , Elena Chiarello , Luca Dellafiora , Gianfranco Picone , Giorgia Antonelli , Clarissa Di Gregorio , Francesco Capozzi , Tullia Tedeschi , Gianni Galaverna , Alessandra Bordoni

A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism.

Toxins

Avec: Jean Lou C M Dorne , Martina Cirlini , Jochem Louisse , Lorenzo Pedroni , Gianni Galaverna , Luca Dellafiora

A systematic review of natural toxins occurrence in plant commodities used for plant-based meat alternatives production.

Food research international (Ottawa, Ont.)

Avec: Octavian Augustin Mihalache , Luca Dellafiora , Chiara Dall'Asta

In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds.

Scientific reports

Avec: Lorenzo Pedroni , Luca Dellafiora , Maria Olga Varrà , Gianni Galaverna , Sergio Ghidini

A mechanistic investigation on kokumi-active γ-Glutamyl tripeptides - A computational study to understand molecular basis of their activity and to identify novel potential kokumi-tasting sequences.

Food research international (Ottawa, Ont.)

Avec: Luca Dellafiora , Fabio Magnaghi , Gianni Galaverna , Chiara Dall'Asta

Risk-benefit assessment of shifting from traditional meat-based diets to alternative dietary patterns.

EFSA journal. European Food Safety Authority

Avec: Octavian Augustin Mihalache , Luca Dellafiora , Chiara Dall'Asta

The bitter side of toxicity: A big data analysis spotted the interaction between trichothecenes and bitter receptors.

Food research international (Ottawa, Ont.)

Avec: Lorenzo Pedroni , Florinda Perugino , Ambra Kurtaga , Gianni Galaverna , Chiara Dall'Asta , Luca Dellafiora

Effects of Chrysin and Chrysin-7-sulfate on Ochratoxin A-Albumin Interactions and on the Plasma and Kidney Levels of the Mycotoxin in Rats.

ACS omega

Avec: Miklós Poór , Ágnes Dombi , Eszter Fliszár-Nyúl , Lorenzo Pedroni , Luca Dellafiora

How D-amino acids embedded in the protein sequence modify its digestibility: Behaviour of digestive enzymes tested on a model peptide used as target.

Food chemistry

Avec: Francesca Accardo , Barbara Prandi , Luca Dellafiora , Tullia Tedeschi , Stefano Sforza

Potential (co-)contamination of dairy milk with AFM1 and MC-LR and their synergistic interaction in inducing mitochondrial dysfunction in HepG2 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Avec: Mohamed F Abdallah , Jessa May Recote , Camille Van Camp , Wannes H R Van Hasse , Lorenzo Pedroni , Luca Dellafiora , Julien Masquelier , Andreja Rajkovic

Réseau de co-auteurs

Chiara Dall'Asta 30 collaborations

Gianni Galaverna 24 collaborations

Lorenzo Pedroni 15 collaborations

Doris Marko 9 collaborations

Georg Aichinger 7 collaborations

Francesco Crudo 6 collaborations

Jochem Louisse 6 collaborations

Giorgia Del Favero 5 collaborations

Tullia Tedeschi 5 collaborations

Florinda Perugino 5 collaborations

Anna Arnoldi 4 collaborations

Carmen Lammi 4 collaborations

Jean Lou C M Dorne 4 collaborations

Carlotta Bollati 3 collaborations

Elisabeth Varga 3 collaborations

Barbara Prandi 3 collaborations

Ans Punt 3 collaborations

Eszter Fliszár-Nyúl 3 collaborations

Miklós Poór 3 collaborations

Giovanna Boschin 3 collaborations

Jovana Mihajlovic 3 collaborations

David Berry 3 collaborations

Octavian Augustin Mihalache 3 collaborations

Mattia Di Nunzio 2 collaborations

Cecilia Loffi 2 collaborations

Elena Chiarello 2 collaborations

Gianfranco Picone 2 collaborations

Giorgia Antonelli 2 collaborations

Francesco Capozzi 2 collaborations

Alessandra Bordoni 2 collaborations

Fabio Magnaghi 2 collaborations

Gabriele Cruciani 2 collaborations

Stefano Sforza 2 collaborations

Jeroen J M W van den Heuvel 2 collaborations

Deborah Rijkers 2 collaborations

Liz Leenders 2 collaborations

Jean-Lou C M Dorne 2 collaborations

Frans G M Russel 2 collaborations

Jan B Koenderink 2 collaborations

Beáta Lemli 2 collaborations

Sándor Kunsági-Máté 2 collaborations

Martina Cirlini 2 collaborations

Benedikt Warth 2 collaborations

Daniele Del Rio 2 collaborations

Foteini Pantazi 1 collaboration

Isabelle P Oswald 1 collaboration

Jean-Lou Dorne 1 collaboration

Paola Battilani 1 collaboration

Raffaele Pugliese 1 collaboration

Fabrizio Gelain 1 collaboration

Julia Hohenbichler 1 collaboration

Serena Montalbano 1 collaboration

Annamaria Buschini 1 collaboration

Marco Zaccaria 1 collaboration

William Dawson 1 collaboration

Darius Russel Kish 1 collaboration

Massimo Reverberi 1 collaboration

Maria Carmela Bonaccorsi di Patti 1 collaboration

Marek Domin 1 collaboration

Viviana Cristiglio 1 collaboration

Bun Chan 1 collaboration

Frank Gabel 1 collaboration

Takahito Nakajima 1 collaboration

Luigi Genovese 1 collaboration

Babak Momeni 1 collaboration

Elena Geib 1 collaboration

Leyre Sánchez-Barrionuevo 1 collaboration

Matthias Brock 1 collaboration

David Cánovas 1 collaboration

Angela Marseglia 1 collaboration

Veronica Lolli 1 collaboration

Pietro Cozzini 1 collaboration

Augusta Caligiani 1 collaboration

Daniel Zocchi Doherty 1 collaboration

Stephen G Bell 1 collaboration

Annelies Noorlander 1 collaboration

Gábor Pethő 1 collaboration

Shiva Ghadiri 1 collaboration

Veronica Spalenza 1 collaboration

Paola Badino 1 collaboration

Andrea Barbarossa 1 collaboration

Carlo Nebbia 1 collaboration

Flavia Girolami 1 collaboration

Gilda Aiello 1 collaboration

Giulia Ranaldi 1 collaboration

Simonetta Ferruzza 1 collaboration

Yula Sambuy 1 collaboration

Endre Kiss 1 collaboration

Lorenzo Del Vecchio 1 collaboration

Leandra Leto 1 collaboration

Federica Russo 1 collaboration

Valeria Guarrasi 1 collaboration

Benedetta Chiancone 1 collaboration

Marthe De Boevre 1 collaboration

Sarah De Saeger 1 collaboration

Antonio Moretti 1 collaboration

Laetitia Pinson-Gadais 1 collaboration

Nadia Ponts 1 collaboration

Florence Richard-Forget 1 collaboration

Antonia Susca 1 collaboration

Raphaela M Mayer 1 collaboration

Lukas Janker 1 collaboration

Laura Niederstaetter 1 collaboration

Christopher Gerner 1 collaboration

Christoph Gonaus 1 collaboration

Barbara Streit 1 collaboration

Wulf-Dieter Moll 1 collaboration

Gudrun Vogtentanz 1 collaboration

Gerd Schatzmayr 1 collaboration

Shreenath Prasad 1 collaboration

Laura Righetti 1 collaboration

Enrico Rolli 1 collaboration

Michele Suman 1 collaboration

Renato Bruni 1 collaboration

M S Lin 1 collaboration

M S Varunjikar 1 collaboration

K K Lie 1 collaboration

L Søfteland 1 collaboration

L Dellafiora 1 collaboration

R Ørnsrud 1 collaboration

M Sanden 1 collaboration

M H G Berntssen 1 collaboration

J L C M Dorne 1 collaboration

V Bafna 1 collaboration

J D Rasinger 1 collaboration

Martina Bartolomei 1 collaboration

Chenyifan Hong 1 collaboration

Lena Burger 1 collaboration

Maximilian Jobst 1 collaboration

Danila Delfino 1 collaboration

Luisa Calcinai 1 collaboration

Erminia Ridolo 1 collaboration

Francesca Nicoletta 1 collaboration

Davide Cavazzini 1 collaboration

Claudia Folli 1 collaboration

Hannes Puntscher 1 collaboration

Marco Milioli 1 collaboration

Angela Falco 1 collaboration

Margherita Interlandi 1 collaboration

Abdelrahman Mohamed 1 collaboration

Martin Frotscher 1 collaboration

Benedetta Riccardi 1 collaboration

Paola Puccini 1 collaboration

Zelma Faisal 1 collaboration

Lajos Szente 1 collaboration

Amelia Barilli 1 collaboration

Pedro Mena 1 collaboration

Bianca Maria Rotoli 1 collaboration

Clarissa Di Gregorio 1 collaboration

Maria Olga Varrà 1 collaboration

Sergio Ghidini 1 collaboration

Ambra Kurtaga 1 collaboration

Ágnes Dombi 1 collaboration

Francesca Accardo 1 collaboration

Mohamed F Abdallah 1 collaboration

Jessa May Recote 1 collaboration

Camille Van Camp 1 collaboration

Wannes H R Van Hasse 1 collaboration

Julien Masquelier 1 collaboration

Andreja Rajkovic 1 collaboration