Lourival D Possani

Affiliations

Instituto de Biotecnología, Universidad Nacional Autónoma de México, Avenida Universidad, 2001, Colonia Chamilpa, Cuernavaca, Morelos, 62210, Mexico. Electronic address: possani@ibt.unam.mx.

Publications (42)

Transcriptomic and proteomic analyses of the venom and venom glands of Centruroides hirsutipalpus, a dangerous scorpion from Mexico.

Toxicon : official journal of the International Society on Toxinology

Avec: Laura L Valdez-Velázquez , Jimena Cid-Uribe , María Teresa Romero-Gutierrez , Timoteo Olamendi-Portugal , Juana María Jimenez-Vargas , Lourival D Possani

Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function.

Toxicon : official journal of the International Society on Toxinology

Avec: G B Gurrola , J I Guijarro , M Delepierre , R L L Mendoza , J I Cid-Uribe , F V Coronas , L D Possani

sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity.

Biochemical pharmacology

Avec: Agota Csoti , Rosby Del Carmen Nájera Meza , Ferenc Bogár , Gabor Tajti , Tibor G Szanto , Zoltan Varga , Georgina B Gurrola , Gábor K Tóth , Lourival D Possani , Gyorgy Panyi

A proteomic overview of the major venom components from Tityus championi from Panama.

Toxicon : official journal of the International Society on Toxinology

Avec: Marcos H Salazar , Magdalena Hernández Ortíz , Sergio Encarnación , Fernando Zamudio , Lourival D Possani , John Cleghorn , Maricruz Morán , Hildaura Acosta , Gerardo Corzo

Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion

Toxins

Avec: Rita Restano-Cassulini , Timoteo Olamendi-Portugal , Lidia Riaño-Umbarila , Fernando Z Zamudio , Gustavo Delgado-Prudencio , Baltazar Becerril , Lourival D Possani

The Dual α-Amidation System in Scorpion Venom Glands.

Toxins

Avec: Gustavo Delgado-Prudencio , Lourival D Possani , Baltazar Becerril , Ernesto Ortiz

Construction and expression of a single-chain variable fragment antibody against chicken DEC 205 for targeting the bacterial expressed hemagglutinin-neuraminidase of Newcastle disease virus.

Veterinary immunology and immunopathology

Avec: David Jáuregui-Zúñiga , Martha Pedraza-Escalona , Rubén Merino-Guzman , Lourival D Possani

Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies.

Molecular immunology

Avec: Lidia Riaño-Umbarila , Vianey Margarita Rojas-Trejo , José Alberto Romero-Moreno , Miguel Costas , Irving Utrera-Espíndola , Timoteo Olamendi-Portugal , Lourival D Possani , Baltazar Becerril

Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus.

Peptides

Avec: Juana María Jiménez-Vargas , Santos Ramírez-Carreto , Gerardo Corzo , Lourival D Possani , Baltazar Becerril , Ernesto Ortiz

Antiseizure potential of peptides from the venom of social wasp Chartergellus communis against chemically-induced seizures.

Toxicon : official journal of the International Society on Toxinology

Avec: Kamila Soares Lopes , Maria Varela Torres Quintanilha , Adolfo Carlos Barros de Souza , Fernando Zamudio-Zuñiga , Lourival Domingos Possani , Márcia Renata Mortari

The Enzymatic Core of Scorpion Venoms.

Toxins

Avec: Gustavo Delgado-Prudencio , Jimena I Cid-Uribe , J Alejandro Morales , Lourival D Possani , Ernesto Ortiz , Teresa Romero-Gutiérrez

Cm28, a scorpion toxin having a unique primary structure, inhibits KV1.2 and KV1.3 with high affinity.

The Journal of general physiology

Avec: Muhammad Umair Naseem , Edson Carcamo-Noriega , José Beltrán-Vidal , Jesus Borrego , Tibor G Szanto , Fernando Z Zamudio , Gustavo Delgado-Prudencio , Lourival D Possani , Gyorgy Panyi

Structural and functional studies of scorpine: A channel blocker and cytolytic peptide.

Toxicon : official journal of the International Society on Toxinology

Avec: Estefanía López-Giraldo , Elisa Carrillo , Gustavo Titaux-Delgado , Patricia Cano-Sánchez , Alland Colorado , Lourival D Possani , Federico Del Río-Portilla

Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion

Toxins

Avec: Jimena I Cid-Uribe , Erika P Meneses , Cesar V F Batista , Ernesto Ortiz , Lourival D Possani

Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion

International journal of peptide research and therapeutics

Avec: Alaa M H El-Bitar , Moustafa Sarhan , Mohamed A Abdel-Rahman , Veronica Quintero-Hernandez , Chie Aoki-Utsubo , Mohsen A Moustafa , Lourival D Possani , Hak Hotta

Colombian Scorpion

Toxins

Avec: José Beltrán-Vidal , Edson Carcamo-Noriega , Nina Pastor , Fernando Zamudio-Zuñiga , Jimmy Alexander Guerrero-Vargas , Santiago Castaño , Lourival Domingos Possani , Rita Restano-Cassulini

Heterologous expression of four recombinant toxins from Panamanian scorpions of the genus

Toxicon: X

Avec: Marcos H Salazar , Herlinda Clement , Ligia L Corrales-García , Jairo Sánchez , John Cleghorn , Fernando Zamudio , Lourival D Possani , Hildaura Acosta , Gerardo Corzo

The Ca

Pharmaceutics

Avec: José Ignacio Veytia-Bucheli , Den Alejandro Alvarado-Velázquez , Lourival Domingos Possani , Roberto González-Amaro , Yvonne Rosenstein

Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K

Toxins

Avec: Muhammad Umair Naseem , Georgina Gurrola-Briones , Margarita R Romero-Imbachi , Jesus Borrego , Edson Carcamo-Noriega , José Beltrán-Vidal , Fernando Z Zamudio , Kashmala Shakeel , Lourival Domingos Possani , Gyorgy Panyi

Development of a human antibody fragment cross-neutralizing scorpion toxins.

Molecular immunology

Avec: José Alberto Romero-Moreno , Hugo Serrano-Posada , Timoteo Olamendi-Portugal , Lourival D Possani , Baltazar Becerril , Lidia Riaño-Umbarila

Of Seven New K

Toxins

Avec: Kashmala Shakeel , Timoteo Olamendi-Portugal , Muhammad Umair Naseem , Baltazar Becerril , Fernando Z Zamudio , Gustavo Delgado-Prudencio , Lourival Domingos Possani , Gyorgy Panyi

Indolealkylamines in the venom of the scorpion Thorellius intrepidus.

Toxicon : official journal of the International Society on Toxinology

Avec: Rodrigo Ibarra-Vega , Juana María Jiménez-Vargas , Armando Pineda-Contreras , Francisco Javier Martínez-Martínez , Carlos Eduardo Barajas-Saucedo , Héctor García-Ortega , Nancy E Magaña-Vergara , Lourival D Possani , Gerardo Corzo , Mario Alberto Gaitan-Hinojosa , Oscar Fernando Vázquez-Vuelvas , Fernando Zamudio , Laura Leticia Valdez-Velazquez

Head-to-Tail Cyclization after Interaction with Trypsin: A Scorpion Venom Peptide that Resembles Plant Cyclotides.

Journal of medicinal chemistry

Avec: Caroline B F Mourão , Guilherme D Brand , João Paulo C Fernandes , Maura V Prates , Carlos Bloch , João Alexandre R G Barbosa , Sônia M Freitas , Rita Restano-Cassulini , Lourival D Possani , Elisabeth F Schwartz

Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.

Journal of proteomics

Avec: Melisa Bénard-Valle , Edgar Neri-Castro , Manuel F Yañez-Mendoza , Bruno Lomonte , Alejandro Olvera , Fernando Zamudio , Rita Restano-Cassulini , Lourival D Possani , Enrique Jiménez-Ferrer , Alejandro Alagón

Structural and functional characterization of toxic peptides purified from the venom of the Colombian scorpion Tityus macrochirus.

Toxicon : official journal of the International Society on Toxinology

Avec: Clara Andrea Rincón-Cortés , Timoteo Olamendi-Portugal , Edson Norberto Carcamo-Noriega , Edmundo González Santillán , Fernando Zamudio Zuñiga , Edgar Antonio Reyes-Montaño , Nohora Angélica Vega Castro , Lourival Domingos Possani

1,4-Benzoquinone antimicrobial agents against

Proceedings of the National Academy of Sciences of the United States of America

Avec: Edson Norberto Carcamo-Noriega , Shyam Sathyamoorthi , Shibdas Banerjee , Elumalai Gnanamani , Monserrat Mendoza-Trujillo , Dulce Mata-Espinosa , Rogelio Hernández-Pando , José Ignacio Veytia-Bucheli , Lourival D Possani , Richard N Zare

Hadrurid Scorpion Toxins: Evolutionary Conservation and Selective Pressures.

Toxins

Avec: Carlos E Santibáñez-López , Matthew R Graham , Prashant P Sharma , Ernesto Ortiz , Lourival D Possani

Toxin Ct1a, from venom of Centruroides tecomanus, modifies the spontaneous firing frequency of neurons in the suprachiasmatic nucleus.

Toxicon : official journal of the International Society on Toxinology

Avec: Javier Alamilla , Juana María Jiménez-Vargas , Alan R Galván-Hernández , Miriam E Reyes-Méndez , Manuel J Bermúdez-Gúzman , Rita Restano-Cassulini , Timoteo Olamendi-Portugal , Fernando Z Zamudio , Lourival D Possani , Laura L Valdez-Velázquez

The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus.

Toxicon : official journal of the International Society on Toxinology

Avec: Andrea Estefanía López-Giraldo , Timoteo Olamendi-Portugal , Lidia Riaño-Umbarila , Baltazar Becerril , Lourival D Possani , Muriel Delepierre , Federico Del Río-Portilla

Full Neutralization of

Toxins

Avec: Lidia Riaño-Umbarila , José Alberto Romero-Moreno , Luis M Ledezma-Candanoza , Timoteo Olamendi-Portugal , Lourival D Possani , Baltazar Becerril

Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus.

Toxicon : official journal of the International Society on Toxinology

Avec: M J Bermúdez-Guzmán , J M Jiménez-Vargas , L D Possani , F Zamudio , G Orozco-Gutiérrez , E Oceguera-Contreras , J N Enríquez-Vara , O F Vazquez-Vuelvas , P E García-Villalvazo , L L Valdez-Velázquez

Toxic Peptides from the Mexican Scorpion

Toxins

Avec: Lidia Riaño-Umbarila , Timoteo Olamendi-Portugal , José Alberto Romero-Moreno , Gustavo Delgado-Prudencio , Fernando Z Zamudio , Baltazar Becerril , Lourival D Possani

Venom components of the scorpion Centruroides limpidus modulate cytokine expression by T helper lymphocytes: Identification of ion channel-related toxins by mass spectrometry.

International immunopharmacology

Avec: Julián M Cota-Arce , Daniela Zazueta-Favela , Fernando Díaz-Castillo , Samanta Jiménez , Johanna Bernáldez-Sarabia , Nadia L Caram-Salas , Kee W L Dan , Galileo Escobedo , Alexei F Licea-Navarro , Lourival D Possani , Marco A De León-Nava

Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.

Biochemical pharmacology

Avec: Karen Luna-Ramirez , Agota Csoti , Jeffrey R McArthur , Yanni K Y Chin , Raveendra Anangi , Rosby Del Carmen Najera , Lourival D Possani , Glenn F King , Gyorgy Panyi , Haibo Yu , David J Adams , Rocio K Finol-Urdaneta

Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico.

Toxicon : official journal of the International Society on Toxinology

Avec: Ilse V Gómez-Ramírez , Lidia Riaño-Umbarila , Timoteo Olamendi-Portugal , Rita Restano-Cassulini , Lourival D Possani , Baltazar Becerril

Biochemical characterization of the venom from the Mexican scorpion Centruroides ornatus, a dangerous species to humans.

Toxicon : official journal of the International Society on Toxinology

Avec: I A García-Guerrero , E Cárcamo-Noriega , F Gómez-Lagunas , E González-Santillán , F Z Zamudio , G B Gurrola , L D Possani

Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K+ channels: A lentiviral vector approach.

PloS one

Avec: Masayoshi Okada , Ernesto Ortiz , Gerardo Corzo , Lourival D Possani

Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms.

Toxins

Avec: Lidia Riaño-Umbarila , Ilse V Gómez-Ramírez , Luis M Ledezma-Candanoza , Timoteo Olamendi-Portugal , Everardo Remi Rodríguez-Rodríguez , Guillermo Fernández-Taboada , Lourival D Possani , Baltazar Becerril

Venom content and toxicity regeneration after venom gland depletion by electrostimulation in the scorpion Centruroides limpidus.

Toxicon : official journal of the International Society on Toxinology

Avec: Edson Norberto Carcamo-Noriega , Lourival Domingos Possani , Ernesto Ortiz

Neutralization of Centruroides tecomanus scorpion venom by the use of two human recombinant antibody fragments.

Molecular immunology

Avec: Hugo Valencia-Martínez , Lidia Riaño-Umbarila , Timoteo Olamendi-Portugal , José Alberto Romero-Moreno , Lourival D Possani , Baltazar Becerril

Flow cytometry analysis of CD11c-positive peripheral blood mononuclear cells in horses.

Veterinary immunology and immunopathology

Avec: Mayela Rosario Espinoza-Duarte , Carlos Ortega-Ochoa , Alejandro Baca-Ramirez , Lourival D Possani , Gerardo P Espino-Solis

Expression in Pichia pastoris of human antibody fragments that neutralize venoms of Mexican scorpions.

Toxicon : official journal of the International Society on Toxinology

Avec: Ilse V Gómez-Ramírez , Ligia Luz Corrales-García , Lourival D Possani , Lidia Riaño-Umbarila , Baltazar Becerril

Réseau de co-auteurs

Timoteo Olamendi-Portugal 13 collaborations

Baltazar Becerril 13 collaborations

Lidia Riaño-Umbarila 10 collaborations

Ernesto Ortiz 7 collaborations

Lourival Domingos Possani 7 collaborations

Rita Restano-Cassulini 6 collaborations

Fernando Z Zamudio 6 collaborations

Gustavo Delgado-Prudencio 6 collaborations

Gyorgy Panyi 5 collaborations

Gerardo Corzo 5 collaborations

José Alberto Romero-Moreno 5 collaborations

Fernando Zamudio 4 collaborations

L D Possani 3 collaborations

Juana María Jiménez-Vargas 3 collaborations

Muhammad Umair Naseem 3 collaborations

Edson Carcamo-Noriega 3 collaborations

José Beltrán-Vidal 3 collaborations

Edson Norberto Carcamo-Noriega 3 collaborations

Ilse V Gómez-Ramírez 3 collaborations

Laura L Valdez-Velázquez 2 collaborations

G B Gurrola 2 collaborations

Agota Csoti 2 collaborations

Tibor G Szanto 2 collaborations

Marcos H Salazar 2 collaborations

John Cleghorn 2 collaborations

Hildaura Acosta 2 collaborations

Fernando Zamudio-Zuñiga 2 collaborations

Jimena I Cid-Uribe 2 collaborations

Jesus Borrego 2 collaborations

Federico Del Río-Portilla 2 collaborations

José Ignacio Veytia-Bucheli 2 collaborations

Kashmala Shakeel 2 collaborations

Luis M Ledezma-Candanoza 2 collaborations

Jimena Cid-Uribe 1 collaboration

María Teresa Romero-Gutierrez 1 collaboration

Juana María Jimenez-Vargas 1 collaboration

J I Guijarro 1 collaboration

M Delepierre 1 collaboration

R L L Mendoza 1 collaboration

J I Cid-Uribe 1 collaboration

F V Coronas 1 collaboration

Rosby Del Carmen Nájera Meza 1 collaboration

Ferenc Bogár 1 collaboration

Gabor Tajti 1 collaboration

Zoltan Varga 1 collaboration

Georgina B Gurrola 1 collaboration

Gábor K Tóth 1 collaboration

Magdalena Hernández Ortíz 1 collaboration

Sergio Encarnación 1 collaboration

Maricruz Morán 1 collaboration

David Jáuregui-Zúñiga 1 collaboration

Martha Pedraza-Escalona 1 collaboration

Rubén Merino-Guzman 1 collaboration

Vianey Margarita Rojas-Trejo 1 collaboration

Miguel Costas 1 collaboration

Irving Utrera-Espíndola 1 collaboration

Santos Ramírez-Carreto 1 collaboration

Kamila Soares Lopes 1 collaboration

Maria Varela Torres Quintanilha 1 collaboration

Adolfo Carlos Barros de Souza 1 collaboration

Márcia Renata Mortari 1 collaboration

J Alejandro Morales 1 collaboration

Teresa Romero-Gutiérrez 1 collaboration

Estefanía López-Giraldo 1 collaboration

Elisa Carrillo 1 collaboration

Gustavo Titaux-Delgado 1 collaboration

Patricia Cano-Sánchez 1 collaboration

Alland Colorado 1 collaboration

Erika P Meneses 1 collaboration

Cesar V F Batista 1 collaboration

Alaa M H El-Bitar 1 collaboration

Moustafa Sarhan 1 collaboration

Mohamed A Abdel-Rahman 1 collaboration

Veronica Quintero-Hernandez 1 collaboration

Chie Aoki-Utsubo 1 collaboration

Mohsen A Moustafa 1 collaboration

Hak Hotta 1 collaboration

Nina Pastor 1 collaboration

Jimmy Alexander Guerrero-Vargas 1 collaboration

Santiago Castaño 1 collaboration

Herlinda Clement 1 collaboration

Ligia L Corrales-García 1 collaboration

Jairo Sánchez 1 collaboration

Den Alejandro Alvarado-Velázquez 1 collaboration

Roberto González-Amaro 1 collaboration

Yvonne Rosenstein 1 collaboration

Georgina Gurrola-Briones 1 collaboration

Margarita R Romero-Imbachi 1 collaboration

Hugo Serrano-Posada 1 collaboration

Rodrigo Ibarra-Vega 1 collaboration

Armando Pineda-Contreras 1 collaboration

Francisco Javier Martínez-Martínez 1 collaboration

Carlos Eduardo Barajas-Saucedo 1 collaboration

Héctor García-Ortega 1 collaboration

Nancy E Magaña-Vergara 1 collaboration

Mario Alberto Gaitan-Hinojosa 1 collaboration

Oscar Fernando Vázquez-Vuelvas 1 collaboration

Laura Leticia Valdez-Velazquez 1 collaboration

Caroline B F Mourão 1 collaboration

Guilherme D Brand 1 collaboration

João Paulo C Fernandes 1 collaboration

Maura V Prates 1 collaboration

Carlos Bloch 1 collaboration

João Alexandre R G Barbosa 1 collaboration

Sônia M Freitas 1 collaboration

Elisabeth F Schwartz 1 collaboration

Melisa Bénard-Valle 1 collaboration

Edgar Neri-Castro 1 collaboration

Manuel F Yañez-Mendoza 1 collaboration

Bruno Lomonte 1 collaboration

Alejandro Olvera 1 collaboration

Enrique Jiménez-Ferrer 1 collaboration

Alejandro Alagón 1 collaboration

Clara Andrea Rincón-Cortés 1 collaboration

Edmundo González Santillán 1 collaboration

Fernando Zamudio Zuñiga 1 collaboration

Edgar Antonio Reyes-Montaño 1 collaboration

Nohora Angélica Vega Castro 1 collaboration

Shyam Sathyamoorthi 1 collaboration

Shibdas Banerjee 1 collaboration

Elumalai Gnanamani 1 collaboration

Monserrat Mendoza-Trujillo 1 collaboration

Dulce Mata-Espinosa 1 collaboration

Rogelio Hernández-Pando 1 collaboration

Richard N Zare 1 collaboration

Carlos E Santibáñez-López 1 collaboration

Matthew R Graham 1 collaboration

Prashant P Sharma 1 collaboration

Javier Alamilla 1 collaboration

Alan R Galván-Hernández 1 collaboration

Miriam E Reyes-Méndez 1 collaboration

Manuel J Bermúdez-Gúzman 1 collaboration

Andrea Estefanía López-Giraldo 1 collaboration

Muriel Delepierre 1 collaboration

M J Bermúdez-Guzmán 1 collaboration

J M Jiménez-Vargas 1 collaboration

F Zamudio 1 collaboration

G Orozco-Gutiérrez 1 collaboration

E Oceguera-Contreras 1 collaboration

J N Enríquez-Vara 1 collaboration

O F Vazquez-Vuelvas 1 collaboration

P E García-Villalvazo 1 collaboration

L L Valdez-Velázquez 1 collaboration

Julián M Cota-Arce 1 collaboration

Daniela Zazueta-Favela 1 collaboration

Fernando Díaz-Castillo 1 collaboration

Samanta Jiménez 1 collaboration

Johanna Bernáldez-Sarabia 1 collaboration

Nadia L Caram-Salas 1 collaboration

Kee W L Dan 1 collaboration

Galileo Escobedo 1 collaboration

Alexei F Licea-Navarro 1 collaboration

Marco A De León-Nava 1 collaboration

Karen Luna-Ramirez 1 collaboration

Jeffrey R McArthur 1 collaboration

Yanni K Y Chin 1 collaboration

Raveendra Anangi 1 collaboration

Rosby Del Carmen Najera 1 collaboration

Glenn F King 1 collaboration

Haibo Yu 1 collaboration

David J Adams 1 collaboration

Rocio K Finol-Urdaneta 1 collaboration

I A García-Guerrero 1 collaboration

E Cárcamo-Noriega 1 collaboration

F Gómez-Lagunas 1 collaboration

E González-Santillán 1 collaboration

F Z Zamudio 1 collaboration

Masayoshi Okada 1 collaboration

Everardo Remi Rodríguez-Rodríguez 1 collaboration

Guillermo Fernández-Taboada 1 collaboration

Hugo Valencia-Martínez 1 collaboration

Mayela Rosario Espinoza-Duarte 1 collaboration

Carlos Ortega-Ochoa 1 collaboration

Alejandro Baca-Ramirez 1 collaboration

Gerardo P Espino-Solis 1 collaboration

Ligia Luz Corrales-García 1 collaboration