Kathryn Koszka

Affiliations

Biogen, Cambridge, MA, USA.

Publications (4)

Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice.

Gene therapy

Avec: Tess Torregrosa , Sydney Lehman , Sam Hana , Galina Marsh , Shanqin Xu , Kathryn Koszka , Nicole Mastrangelo , Alexander McCampbell , Christopher E Henderson , Shih-Ching Lo

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection.

Molecular therapy. Nucleic acids

Avec: Shukkwan K Chen , Zachary C E Hawley , Maria I Zavodszky , Sam Hana , Daniel Ferretti , Branka Grubor , Michael Hawes , Shanqin Xu , Stefan Hamann , Galina Marsh , Patrick Cullen , Ravi Challa , Thomas M Carlile , Hang Zhang , Wan-Hung Lee , Andrea Peralta , Pete Clarner , Cong Wei , Kathryn Koszka , Feng Gao , Shih-Ching Lo

Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice.

Gene therapy

Avec: Sam Hana , Michael Peterson , Helen McLaughlin , Eric Marshall , Attila J Fabian , Olivia McKissick , Kathryn Koszka , Galina Marsh , Michael Craft , Shanqin Xu , Alexander Sorets , Tess Torregrosa , Chao Sun , Chris E Henderson , Shih-Ching Lo

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model.

Gene therapy

Avec: Yi A Chen , Mark W Kankel , Sam Hana , Shukkwan Kelly Lau , Maria I Zavodszky , Olivia McKissick , Nicole Mastrangelo , Jessica Dion , Bin Wang , Daniel Ferretti , David Koske , Sydney Lehman , Kathryn Koszka , Helen McLaughlin , Mei Liu , Eric Marshall , Attila J Fabian , Patrick Cullen , Galina Marsh , Stefan Hamann , Michael Craft , Jennifer Sebalusky , H Moore Arnold , Rachelle Driscoll , Adam Sheehy , Yi Luo , Sonia Manca , Thomas Carlile , Chao Sun , Kirsten Sigrist , Alexander McCampbell , Christopher E Henderson , Shih-Ching Lo

Réseau de co-auteurs

Sam Hana 4 collaborations

Galina Marsh 4 collaborations

Shih-Ching Lo 4 collaborations

Shanqin Xu 3 collaborations

Tess Torregrosa 2 collaborations

Sydney Lehman 2 collaborations

Nicole Mastrangelo 2 collaborations

Alexander McCampbell 2 collaborations

Christopher E Henderson 2 collaborations

Maria I Zavodszky 2 collaborations

Daniel Ferretti 2 collaborations

Stefan Hamann 2 collaborations

Patrick Cullen 2 collaborations

Helen McLaughlin 2 collaborations

Eric Marshall 2 collaborations

Attila J Fabian 2 collaborations

Olivia McKissick 2 collaborations

Michael Craft 2 collaborations

Chao Sun 2 collaborations

Shukkwan K Chen 1 collaboration

Zachary C E Hawley 1 collaboration

Branka Grubor 1 collaboration

Michael Hawes 1 collaboration

Ravi Challa 1 collaboration

Thomas M Carlile 1 collaboration

Hang Zhang 1 collaboration

Wan-Hung Lee 1 collaboration

Andrea Peralta 1 collaboration

Pete Clarner 1 collaboration

Cong Wei 1 collaboration

Feng Gao 1 collaboration

Michael Peterson 1 collaboration

Alexander Sorets 1 collaboration

Chris E Henderson 1 collaboration

Yi A Chen 1 collaboration

Mark W Kankel 1 collaboration

Shukkwan Kelly Lau 1 collaboration

Jessica Dion 1 collaboration

Bin Wang 1 collaboration

David Koske 1 collaboration

Mei Liu 1 collaboration

Jennifer Sebalusky 1 collaboration

H Moore Arnold 1 collaboration

Rachelle Driscoll 1 collaboration

Adam Sheehy 1 collaboration

Yi Luo 1 collaboration

Sonia Manca 1 collaboration

Thomas Carlile 1 collaboration

Kirsten Sigrist 1 collaboration