Kathleen E DelGiorno

Affiliations

Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA kathleen.delgiorno@vanderbilt.edu oren.parnas@gmail.com.
Vanderbilt Digestive Disease Research Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

ORCID: 0000-0002-5749-8394

Publications (18)

It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease.

Gut

Avec: Amelia T Cephas , William L Hwang , Anirban Maitra , Oren Parnas , Kathleen E DelGiorno

Metaplastic tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer.

bioRxiv : the preprint server for biology

Avec: Daniel J Salas-Escabillas , Megan T Hoffman , Jacee S Moore , Sydney M Brender , Hui-Ju Wen , Simone Benitz , Erick T Davis , Dan Long , Allison M Wombwell , Nina G Steele , Rosalie C Sears , Ichiro Matsumoto , Kathleen E DelGiorno , Howard C Crawford

Cysteine depletion induces pancreatic tumor ferroptosis in mice.

Science (New York, N.Y.)

Avec: Michael A Badgley , Daniel M Kremer , H Carlo Maurer , Kathleen E DelGiorno , Ho-Joon Lee , Vinee Purohit , Irina R Sagalovskiy , Alice Ma , Jonathan Kapilian , Christina E M Firl , Amanda R Decker , Steve A Sastra , Carmine F Palermo , Leonardo R Andrade , Peter Sajjakulnukit , Li Zhang , Zachary P Tolstyka , Tal Hirschhorn , Candice Lamb , Tong Liu , Wei Gu , E Scott Seeley , Everett Stone , George Georgiou , Uri Manor , Alina Iuga , Geoffrey M Wahl , Brent R Stockwell , Costas A Lyssiotis , Kenneth P Olive

Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis.

Frontiers in physiology

Avec: Kathleen E DelGiorno , Razia F Naeem , Linjing Fang , Chi-Yeh Chung , Cynthia Ramos , Natalie Luhtala , Carolyn O'Connor , Tony Hunter , Uri Manor , Geoffrey M Wahl

Eicosanoids in the pancreatic tumor microenvironment - a multicellular, multifaceted progression.

Gastro hep advances

Avec: Vikas B Gubbala , Nidhi Jytosana , Vincent Q Trinh , H Carlo Maurer , Razia F Naeem , Nikki K Lytle , Zhibo Ma , Steven Zhao , Wei Lin , Haiyong Han , Yu Shi , Tony Hunter , Pankaj K Singh , Kenneth P Olive , Marcus C B Tan , Susan M Kaech , Geoffrey M Wahl , Kathleen E DelGiorno

Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D

Gastroenterology

Avec: Kathleen E DelGiorno , Chi-Yeh Chung , Vera Vavinskaya , H Carlo Maurer , Sammy Weiser Novak , Nikki K Lytle , Zhibo Ma , Rajshekhar R Giraddi , Dezhen Wang , Linjing Fang , Razia F Naeem , Leonardo R Andrade , Wahida H Ali , Hubert Tseng , Crystal Tsui , Vikas B Gubbala , Maya Ridinger-Saison , Makoto Ohmoto , Galina A Erikson , Carolyn O'Connor , Maxim Nikolaievich Shokhirev , Nasun Hah , Yoshihiro Urade , Ichiro Matsumoto , Susan M Kaech , Pankaj K Singh , Uri Manor , Kenneth P Olive , Geoffrey M Wahl

Peak density of immature nerve cells occurs with high-grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas.

The Journal of pathology

Avec: Vincent Quoc-Huy Trinh , Joseph Thomas Roland , Jahg Wong , Frank Revetta , Krutika Patel , Chanjuan Shi , Kathleen E DelGiorno , Bruce D Carter , Marcus Chuan Beng Tan

Differential spatial distribution of HNF4α isoforms during dysplastic progression of intraductal papillary mucinous neoplasms of the pancreas.

Scientific reports

Avec: Jahg Wong , Vincent Q Trinh , Nidhi Jyotsana , Jumanah F Baig , Frank Revetta , Chanjuan Shi , Anna L Means , Kathleen E DelGiorno , Marcus Tan

Acute tuft cell ablation induces malabsorption and alterations in secretory and immune cell lineages in small intestine.

bioRxiv : the preprint server for biology

Avec: Michael Momoh , Francisca Adeniran , Cynthia Ramos , Kathleen E DelGiorno , Hiroshi Seno , Joseph T Roland , Izumi Kaji

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

Nature

Avec: Yu Shi , Weina Gao , Nikki K Lytle , Peiwu Huang , Xiao Yuan , Amanda M Dann , Maya Ridinger-Saison , Kathleen E DelGiorno , Corina E Antal , Gaoyang Liang , Annette R Atkins , Galina Erikson , Huaiyu Sun , Jill Meisenhelder , Elena Terenziani , Gyunghwi Woo , Linjing Fang , Thom P Santisakultarm , Uri Manor , Ruilian Xu , Carlos R Becerra , Erkut Borazanci , Daniel D Von Hoff , Paul M Grandgenett , Michael A Hollingsworth , Mathias Leblanc , Sarah E Umetsu , Eric A Collisson , Miriam Scadeng , Andrew M Lowy , Timothy R Donahue , Tannishtha Reya , Michael Downes , Ronald M Evans , Geoffrey M Wahl , Tony Pawson , Ruijun Tian , Tony Hunter

Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury.

Gastroenterology

Avec: Zhibo Ma , Nikki K Lytle , Bob Chen , Nidhi Jyotsana , Sammy Weiser Novak , Charles J Cho , Leah Caplan , Olivia Ben-Levy , Abigail C Neininger , Dylan T Burnette , Vincent Q Trinh , Marcus C B Tan , Emilee A Patterson , Rafael Arrojo E Drigo , Rajshekhar R Giraddi , Cynthia Ramos , Anna L Means , Ichiro Matsumoto , Uri Manor , Jason C Mills , James R Goldenring , Ken S Lau , Geoffrey M Wahl , Kathleen E DelGiorno

New insights into tuft cell formation: Implications for structure-function relationships.

Current opinion in cell biology

Avec: Claire E O'Leary , Zhibo Ma , Taylor Culpepper , Sammy Weiser Novak , Kathleen E DelGiorno

Resolution of acinar dedifferentiation regulates tissue remodeling in pancreatic injury and cancer initiation.

Gastroenterology

Avec: Jonathan Baldan , Juan Camacho-Roda , Marta Ballester , Kristina Høj , Anita Kurilla , H Carlo Maurer , Sebastian Arcila-Barrera , Xinyi Lin , Zhaolong Pan , Joana Leitão Castro , Alejandro Enrique Mayorca Guiliani , Charlotte Vestrup Rift , Jane Hasselby , Luc Bouwens , Véronique Lefebvre , Charles J David , Oren Parnas , Kathleen E DelGiorno , Janine Erler , Ilse Rooman , Luis Arnes

CD73-generated extracellular adenosine promotes resolution of neutrophil-mediated tissue injury and restrains metaplasia in pancreatitis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Baylee J O'Brien , Erika Y Faraoni , Lincoln N Strickland , Zhibo Ma , Victoria Mota , Samantha Mota , Xuebo Chen , Tingting Mills , Holger K Eltzschig , Kathleen E DelGiorno , Jennifer M Bailey-Lundberg

Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis.

Frontiers in physiology

Avec: Leah R Caplan , Vera Vavinskaya , David G Gelikman , Nidhi Jyotsana , Vincent Q Trinh , Kenneth P Olive , Marcus C B Tan , Kathleen E DelGiorno

The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer.

Frontiers in oncology

Avec: Nidhi Jyotsana , Kenny T Ta , Kathleen E DelGiorno

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation.

Cell systems

Avec: Frederick R Adler , Alexander R A Anderson , Abhinav Bhushan , Paul Bogdan , Jose Javier Bravo-Cordero , Amy Brock , Yun Chen , Edna Cukierman , Kathleen E DelGiorno , Gerald V Denis , Meghan C Ferrall-Fairbanks , Zev Jordan Gartner , Ronald N Germain , Deborah M Gordon , Ginger Hunter , Mohit Kumar Jolly , Loukia Georgiou Karacosta , Karthikeyan Mythreye , Parag Katira , Rajan P Kulkarni , Matthew L Kutys , Arthur D Lander , Ashley M Laughney , Herbert Levine , Emil Lou , Pedro R Lowenstein , Kristyn S Masters , Dana Pe'er , Shelly R Peyton , Manu O Platt , Jeremy E Purvis , Gerald Quon , Jennifer K Richer , Nicole C Riddle , Analiz Rodriguez , Joshua C Snyder , Gregory Lee Szeto , Claire J Tomlin , Itai Yanai , Ioannis K Zervantonakis , Hannah Dueck

Oncogenic GNAS drives a gastric pylorus program in intraductal papillary mucinous neoplasms of the pancreas.

bioRxiv : the preprint server for biology

Avec: Vincent Quoc-Huy Trinh , Katherine E Ankenbauer , Jiayue Liu , Maelle Batardiere , H Carlo Maurer , Celina Copeland , Jahg Wong , Olivia Ben-Levy , Sabrina M Torbit , Brenda Jarvis , Frank Revetta , Sergey Ivanov , Nidhi Jyotsana , Yuki Makino , Amanda M Ruelas , Anna L Means , Anirban Maitra , Marcus C B Tan , Kathleen E DelGiorno

Réseau de co-auteurs

Geoffrey M Wahl 6 collaborations

H Carlo Maurer 5 collaborations

Uri Manor 5 collaborations

Zhibo Ma 5 collaborations

Nidhi Jyotsana 5 collaborations

Kenneth P Olive 4 collaborations

Vincent Q Trinh 4 collaborations

Nikki K Lytle 4 collaborations

Marcus C B Tan 4 collaborations

Ichiro Matsumoto 3 collaborations

Razia F Naeem 3 collaborations

Linjing Fang 3 collaborations

Cynthia Ramos 3 collaborations

Tony Hunter 3 collaborations

Sammy Weiser Novak 3 collaborations

Jahg Wong 3 collaborations

Frank Revetta 3 collaborations

Anna L Means 3 collaborations

Anirban Maitra 2 collaborations

Oren Parnas 2 collaborations

Leonardo R Andrade 2 collaborations

Chi-Yeh Chung 2 collaborations

Carolyn O'Connor 2 collaborations

Vikas B Gubbala 2 collaborations

Yu Shi 2 collaborations

Pankaj K Singh 2 collaborations

Susan M Kaech 2 collaborations

Vera Vavinskaya 2 collaborations

Rajshekhar R Giraddi 2 collaborations

Maya Ridinger-Saison 2 collaborations

Vincent Quoc-Huy Trinh 2 collaborations

Chanjuan Shi 2 collaborations

Olivia Ben-Levy 2 collaborations

Amelia T Cephas 1 collaboration

William L Hwang 1 collaboration

Daniel J Salas-Escabillas 1 collaboration

Megan T Hoffman 1 collaboration

Jacee S Moore 1 collaboration

Sydney M Brender 1 collaboration

Hui-Ju Wen 1 collaboration

Simone Benitz 1 collaboration

Erick T Davis 1 collaboration

Dan Long 1 collaboration

Allison M Wombwell 1 collaboration

Nina G Steele 1 collaboration

Rosalie C Sears 1 collaboration

Howard C Crawford 1 collaboration

Michael A Badgley 1 collaboration

Daniel M Kremer 1 collaboration

Ho-Joon Lee 1 collaboration

Vinee Purohit 1 collaboration

Irina R Sagalovskiy 1 collaboration

Alice Ma 1 collaboration

Jonathan Kapilian 1 collaboration

Christina E M Firl 1 collaboration

Amanda R Decker 1 collaboration

Steve A Sastra 1 collaboration

Carmine F Palermo 1 collaboration

Peter Sajjakulnukit 1 collaboration

Li Zhang 1 collaboration

Zachary P Tolstyka 1 collaboration

Tal Hirschhorn 1 collaboration

Candice Lamb 1 collaboration

Tong Liu 1 collaboration

Wei Gu 1 collaboration

E Scott Seeley 1 collaboration

Everett Stone 1 collaboration

George Georgiou 1 collaboration

Alina Iuga 1 collaboration

Brent R Stockwell 1 collaboration

Costas A Lyssiotis 1 collaboration

Natalie Luhtala 1 collaboration

Nidhi Jytosana 1 collaboration

Steven Zhao 1 collaboration

Wei Lin 1 collaboration

Haiyong Han 1 collaboration

Dezhen Wang 1 collaboration

Wahida H Ali 1 collaboration

Hubert Tseng 1 collaboration

Crystal Tsui 1 collaboration

Makoto Ohmoto 1 collaboration

Galina A Erikson 1 collaboration

Maxim Nikolaievich Shokhirev 1 collaboration

Nasun Hah 1 collaboration

Yoshihiro Urade 1 collaboration

Joseph Thomas Roland 1 collaboration

Krutika Patel 1 collaboration

Bruce D Carter 1 collaboration

Marcus Chuan Beng Tan 1 collaboration

Jumanah F Baig 1 collaboration

Marcus Tan 1 collaboration

Michael Momoh 1 collaboration

Francisca Adeniran 1 collaboration

Hiroshi Seno 1 collaboration

Joseph T Roland 1 collaboration

Izumi Kaji 1 collaboration

Weina Gao 1 collaboration

Peiwu Huang 1 collaboration

Xiao Yuan 1 collaboration

Amanda M Dann 1 collaboration

Corina E Antal 1 collaboration

Gaoyang Liang 1 collaboration

Annette R Atkins 1 collaboration

Galina Erikson 1 collaboration

Huaiyu Sun 1 collaboration

Jill Meisenhelder 1 collaboration

Elena Terenziani 1 collaboration

Gyunghwi Woo 1 collaboration

Thom P Santisakultarm 1 collaboration

Ruilian Xu 1 collaboration

Carlos R Becerra 1 collaboration

Erkut Borazanci 1 collaboration

Daniel D Von Hoff 1 collaboration

Paul M Grandgenett 1 collaboration

Michael A Hollingsworth 1 collaboration

Mathias Leblanc 1 collaboration

Sarah E Umetsu 1 collaboration

Eric A Collisson 1 collaboration

Miriam Scadeng 1 collaboration

Andrew M Lowy 1 collaboration

Timothy R Donahue 1 collaboration

Tannishtha Reya 1 collaboration

Michael Downes 1 collaboration

Ronald M Evans 1 collaboration

Tony Pawson 1 collaboration

Ruijun Tian 1 collaboration

Bob Chen 1 collaboration

Charles J Cho 1 collaboration

Leah Caplan 1 collaboration

Abigail C Neininger 1 collaboration

Dylan T Burnette 1 collaboration

Emilee A Patterson 1 collaboration

Rafael Arrojo E Drigo 1 collaboration

Jason C Mills 1 collaboration

James R Goldenring 1 collaboration

Ken S Lau 1 collaboration

Claire E O'Leary 1 collaboration

Taylor Culpepper 1 collaboration

Jonathan Baldan 1 collaboration

Juan Camacho-Roda 1 collaboration

Marta Ballester 1 collaboration

Kristina Høj 1 collaboration

Anita Kurilla 1 collaboration

Sebastian Arcila-Barrera 1 collaboration

Xinyi Lin 1 collaboration

Zhaolong Pan 1 collaboration

Joana Leitão Castro 1 collaboration

Alejandro Enrique Mayorca Guiliani 1 collaboration

Charlotte Vestrup Rift 1 collaboration

Jane Hasselby 1 collaboration

Luc Bouwens 1 collaboration

Véronique Lefebvre 1 collaboration

Charles J David 1 collaboration

Janine Erler 1 collaboration

Ilse Rooman 1 collaboration

Luis Arnes 1 collaboration

Baylee J O'Brien 1 collaboration

Erika Y Faraoni 1 collaboration

Lincoln N Strickland 1 collaboration

Victoria Mota 1 collaboration

Samantha Mota 1 collaboration

Xuebo Chen 1 collaboration

Tingting Mills 1 collaboration

Holger K Eltzschig 1 collaboration

Jennifer M Bailey-Lundberg 1 collaboration

Leah R Caplan 1 collaboration

David G Gelikman 1 collaboration

Kenny T Ta 1 collaboration

Frederick R Adler 1 collaboration

Alexander R A Anderson 1 collaboration

Abhinav Bhushan 1 collaboration

Paul Bogdan 1 collaboration

Jose Javier Bravo-Cordero 1 collaboration

Amy Brock 1 collaboration

Yun Chen 1 collaboration

Edna Cukierman 1 collaboration

Gerald V Denis 1 collaboration

Meghan C Ferrall-Fairbanks 1 collaboration

Zev Jordan Gartner 1 collaboration

Ronald N Germain 1 collaboration

Deborah M Gordon 1 collaboration

Ginger Hunter 1 collaboration

Mohit Kumar Jolly 1 collaboration

Loukia Georgiou Karacosta 1 collaboration

Karthikeyan Mythreye 1 collaboration

Parag Katira 1 collaboration

Rajan P Kulkarni 1 collaboration

Matthew L Kutys 1 collaboration

Arthur D Lander 1 collaboration

Ashley M Laughney 1 collaboration

Herbert Levine 1 collaboration

Emil Lou 1 collaboration

Pedro R Lowenstein 1 collaboration

Kristyn S Masters 1 collaboration

Dana Pe'er 1 collaboration

Shelly R Peyton 1 collaboration

Manu O Platt 1 collaboration

Jeremy E Purvis 1 collaboration

Gerald Quon 1 collaboration

Jennifer K Richer 1 collaboration

Nicole C Riddle 1 collaboration

Analiz Rodriguez 1 collaboration

Joshua C Snyder 1 collaboration

Gregory Lee Szeto 1 collaboration

Claire J Tomlin 1 collaboration

Itai Yanai 1 collaboration

Ioannis K Zervantonakis 1 collaboration

Hannah Dueck 1 collaboration

Katherine E Ankenbauer 1 collaboration

Jiayue Liu 1 collaboration

Maelle Batardiere 1 collaboration

Celina Copeland 1 collaboration

Sabrina M Torbit 1 collaboration

Brenda Jarvis 1 collaboration

Sergey Ivanov 1 collaboration

Yuki Makino 1 collaboration

Amanda M Ruelas 1 collaboration