Karl S A Vallin

Affiliations

Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Solna, Sweden.

Publications (2)

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.

Nature cancer

Avec: Nadilly Bonagas , Nina M S Gustafsson , Martin Henriksson , Petra Marttila , Robert Gustafsson , Elisée Wiita , Sanjay Borhade , Alanna C Green , Karl S A Vallin , Antonio Sarno , Richard Svensson , Camilla Göktürk , Therese Pham , Ann-Sofie Jemth , Olga Loseva , Victoria Cookson , Nicole Kiweler , Lars Sandberg , Azita Rasti , Judith E Unterlass , Martin Haraldsson , Yasmin Andersson , Emma R Scaletti , Christoffer Bengtsson , Cynthia B J Paulin , Kumar Sanjiv , Eldar Abdurakhmanov , Linda Pudelko , Ben Kunz , Matthieu Desroses , Petar Iliev , Katarina Färnegårdh , Andreas Krämer , Neeraj Garg , Maurice Michel , Sara Häggblad , Malin Jarvius , Christina Kalderén , Amanda Bögedahl Jensen , Ingrid Almlöf , Stella Karsten , Si Min Zhang , Maria Häggblad , Anders Eriksson , Jianping Liu , Björn Glinghammar , Natalia Nekhotiaeva , Fredrik Klingegård , Tobias Koolmeister , Ulf Martens , Sabin Llona-Minguez , Ruth Moulson , Helena Nordström , Vendela Parrow , Leif Dahllund , Birger Sjöberg , Irene L Vargas , Duy Duc Vo , Johan Wannberg , Stefan Knapp , Hans E Krokan , Per I Arvidsson , Martin Scobie , Johannes Meiser , Pål Stenmark , Ulrika Warpman Berglund , Evert J Homan , Thomas Helleday

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.

Nature metabolism

Avec: Alanna C Green , Petra Marttila , Nicole Kiweler , Christina Chalkiadaki , Elisée Wiita , Victoria Cookson , Antoine Lesur , Kim Eiden , François Bernardin , Karl S A Vallin , Sanjay Borhade , Maeve Long , Elahe Kamali Ghahe , Julio J Jiménez-Alonso , Ann-Sofie Jemth , Olga Loseva , Oliver Mortusewicz , Marianne Meyers , Elodie Viry , Annika I Johansson , Ondřej Hodek , Evert Homan , Nadilly Bonagas , Louise Ramos , Lars Sandberg , Morten Frödin , Etienne Moussay , Ana Slipicevic , Elisabeth Letellier , Jérôme Paggetti , Claus Storgaard Sørensen , Thomas Helleday , Martin Henriksson , Johannes Meiser

Réseau de co-auteurs

Nadilly Bonagas 2 collaborations

Martin Henriksson 2 collaborations

Petra Marttila 2 collaborations

Elisée Wiita 2 collaborations

Sanjay Borhade 2 collaborations

Alanna C Green 2 collaborations

Ann-Sofie Jemth 2 collaborations

Olga Loseva 2 collaborations

Victoria Cookson 2 collaborations

Nicole Kiweler 2 collaborations

Lars Sandberg 2 collaborations

Johannes Meiser 2 collaborations

Thomas Helleday 2 collaborations

Nina M S Gustafsson 1 collaboration

Robert Gustafsson 1 collaboration

Antonio Sarno 1 collaboration

Richard Svensson 1 collaboration

Camilla Göktürk 1 collaboration

Therese Pham 1 collaboration

Azita Rasti 1 collaboration

Judith E Unterlass 1 collaboration

Martin Haraldsson 1 collaboration

Yasmin Andersson 1 collaboration

Emma R Scaletti 1 collaboration

Christoffer Bengtsson 1 collaboration

Cynthia B J Paulin 1 collaboration

Kumar Sanjiv 1 collaboration

Eldar Abdurakhmanov 1 collaboration

Linda Pudelko 1 collaboration

Ben Kunz 1 collaboration

Matthieu Desroses 1 collaboration

Petar Iliev 1 collaboration

Katarina Färnegårdh 1 collaboration

Andreas Krämer 1 collaboration

Neeraj Garg 1 collaboration

Maurice Michel 1 collaboration

Sara Häggblad 1 collaboration

Malin Jarvius 1 collaboration

Christina Kalderén 1 collaboration

Amanda Bögedahl Jensen 1 collaboration

Ingrid Almlöf 1 collaboration

Stella Karsten 1 collaboration

Si Min Zhang 1 collaboration

Maria Häggblad 1 collaboration

Anders Eriksson 1 collaboration

Jianping Liu 1 collaboration

Björn Glinghammar 1 collaboration

Natalia Nekhotiaeva 1 collaboration

Fredrik Klingegård 1 collaboration

Tobias Koolmeister 1 collaboration

Ulf Martens 1 collaboration

Sabin Llona-Minguez 1 collaboration

Ruth Moulson 1 collaboration

Helena Nordström 1 collaboration

Vendela Parrow 1 collaboration

Leif Dahllund 1 collaboration

Birger Sjöberg 1 collaboration

Irene L Vargas 1 collaboration

Duy Duc Vo 1 collaboration

Johan Wannberg 1 collaboration

Stefan Knapp 1 collaboration

Hans E Krokan 1 collaboration

Per I Arvidsson 1 collaboration

Martin Scobie 1 collaboration

Pål Stenmark 1 collaboration

Ulrika Warpman Berglund 1 collaboration

Evert J Homan 1 collaboration

Christina Chalkiadaki 1 collaboration

Antoine Lesur 1 collaboration

Kim Eiden 1 collaboration

François Bernardin 1 collaboration

Maeve Long 1 collaboration

Elahe Kamali Ghahe 1 collaboration

Julio J Jiménez-Alonso 1 collaboration

Oliver Mortusewicz 1 collaboration

Marianne Meyers 1 collaboration

Elodie Viry 1 collaboration

Annika I Johansson 1 collaboration

Ondřej Hodek 1 collaboration

Evert Homan 1 collaboration

Louise Ramos 1 collaboration

Morten Frödin 1 collaboration

Etienne Moussay 1 collaboration

Ana Slipicevic 1 collaboration

Elisabeth Letellier 1 collaboration

Jérôme Paggetti 1 collaboration

Claus Storgaard Sørensen 1 collaboration