Kari Kopra

Affiliations

Department of Chemistry, Chemistry of Drug Development, University of Turku, Vatselankatu 2, 20500 Turku, Finland.

Publications (22)

Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique.

Analytical chemistry

Avec: Salla Valtonen , Emmiliisa Vuorinen , Taru Kariniemi , Ville Eskonen , John Le Quesne , Martin Bushell , Harri Härmä , Kari Kopra

Methods to Monitor Ras Activation State.

Methods in molecular biology (Clifton, N.J.)

Avec: Kari Kopra , Harri Härmä

Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications.

ACS omega

Avec: Ville Eskonen , Natalia Tong-Ochoa , Salla Valtonen , Kari Kopra , Harri Härmä

Protease Substrate-Independent Universal Assay for Monitoring Digestion of Native Unmodified Proteins.

International journal of molecular sciences

Avec: Emmiliisa Vuorinen , Salla Valtonen , Nazia Hassan , Randa Mahran , Huda Habib , Morteza Malakoutikhah , Kari Kopra , Harri Härmä

Homogeneous peptide-break assay for luminescent detection of enzymatic protein post-translational modification activity utilizing charged peptides.

Analytica chimica acta

Avec: Kari Kopra , Natalia Tong-Ochoa , Mari Laine , Ville Eskonen , Päivi J Koskinen , Harri Härmä

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Genome biology

Avec: Ania Wilczynska , Sarah L Gillen , Tobias Schmidt , Hedda A Meijer , Rebekah Jukes-Jones , Claudia Langlais , Kari Kopra , Wei-Ting Lu , Jack D Godfrey , Benjamin R Hawley , Kelly Hodge , Sara Zanivan , Kelvin Cain , John Le Quesne , Martin Bushell

Luminophore Chemistry for Detection of Urinary Bladder Cancer - Comparison to Cytology and Urinary Rapid Tests (BTA stat

Anticancer research

Avec: Thorsten H Ecke , Mikolaj Scislowski , Nazia Hassan , Mari Saura , Steffen Hallmann , Stefan Koch , Sari Vuolle , Morteza Malakoutikhah , Kari Kopra , Harri Härmä

Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability.

International journal of molecular sciences

Avec: Kari Kopra , Salla Valtonen , Randa Mahran , Jonas N Kapp , Nazia Hassan , William Gillette , Bryce Dennis , Lianbo Li , Kenneth D Westover , Andreas Plückthun , Harri Härmä

Isothermal chemical denaturation assay for monitoring protein stability and inhibitor interactions.

Scientific reports

Avec: Randa Mahran , Niklas Vello , Anita Komulainen , Morteza Malakoutikhah , Harri Härmä , Kari Kopra

QTR-FRET: Efficient background reduction technology in time-resolved förster resonance energy transfer assays.

Analytica chimica acta

Avec: Markku Syrjänpää , Emmiliisa Vuorinen , Sakari Kulmala , Qi Wang , Harri Härmä , Kari Kopra

Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring.

Analytical chemistry

Avec: Kari Kopra , Emmiliisa Vuorinen , Maria Abreu-Blanco , Qi Wang , Ville Eskonen , William Gillette , Arto T Pulliainen , Matthew Holderfield , Harri Härmä

Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies.

mAbs

Avec: Salla Valtonen , Emmiliisa Vuorinen , Ville Eskonen , Morteza Malakoutikhah , Kari Kopra , Harri Härmä

Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes.

Analytical chemistry

Avec: Morteza Malakoutikhah , Randa Mahran , Negin Gooran , Ahmadreza Masoumi , Katri Lundell , Arto Liljeblad , Keelan Guiley , Shizhong Dai , Qinheng Zheng , Lawrence Zhu , Kevan M Shokat , Kari Kopra , Harri Härmä

Luminescence-Based Techniques for KRAS Thermal Stability Monitoring.

Methods in molecular biology (Clifton, N.J.)

Avec: Kari Kopra

Fluorescence-Based Protein Stability Monitoring-A Review.

International journal of molecular sciences

Avec: Negin Gooran , Kari Kopra

Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96.

ACS chemical biology

Avec: Randa Mahran , Jonas N Kapp , Salla Valtonen , Allison Champagne , Jinying Ning , William Gillette , Andrew G Stephen , Feng Hao , Andreas Plückthun , Harri Härmä , Tatu Pantsar , Kari Kopra

Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein-Ligand Interaction Studies.

Analytical chemistry

Avec: Emmiliisa Vuorinen , Salla Valtonen , Ville Eskonen , Taru Kariniemi , Jelena Jakovleva , Kari Kopra , Harri Härmä

Single-Peptide TR-FRET Detection Platform for Cysteine-Specific Post-Translational Modifications.

Analytical chemistry

Avec: Ville Eskonen , Natalia Tong-Ochoa , Leena Mattsson , Moona Miettinen , Mika Lastusaari , Arto T Pulliainen , Kari Kopra , Harri Härmä

High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors.

Analytical biochemistry

Avec: Ganesh Babu Manoharan , Kari Kopra , Ville Eskonen , Harri Härmä , Daniel Abankwa

Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases.

Scientific reports

Avec: Kari Kopra , Iraida Sharina , Emil Martin , Harri Härmä

Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence.

Analytical and bioanalytical chemistry

Avec: Kari Kopra , Nazia Hassan , Emmiliisa Vuorinen , Salla Valtonen , Randa Mahran , Huda Habib , Pinja Jalkanen , Petri Susi , Vesa Hytönen , Minna Hankaniemi , Seppo Ylä-Herttuala , Laura Kakkola , Markus Peurla , Harri Härmä

Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc

Analytical and bioanalytical chemistry

Avec: Kari Kopra , Randa Mahran , Titta Yli-Hollo , Sho Tabata , Emmiliisa Vuorinen , Yuki Fujii , Iida Vuorinen , Aki Ogawa-Iio , Akiyoshi Hirayama , Tomoyoshi Soga , Atsuo T Sasaki , Harri Härmä

Réseau de co-auteurs

Harri Härmä 19 collaborations

Salla Valtonen 8 collaborations

Emmiliisa Vuorinen 8 collaborations

Ville Eskonen 8 collaborations

Randa Mahran 7 collaborations

Morteza Malakoutikhah 5 collaborations

Nazia Hassan 4 collaborations

Natalia Tong-Ochoa 3 collaborations

William Gillette 3 collaborations

Taru Kariniemi 2 collaborations

John Le Quesne 2 collaborations

Martin Bushell 2 collaborations

Huda Habib 2 collaborations

Jonas N Kapp 2 collaborations

Andreas Plückthun 2 collaborations

Qi Wang 2 collaborations

Arto T Pulliainen 2 collaborations

Negin Gooran 2 collaborations

Mari Laine 1 collaboration

Päivi J Koskinen 1 collaboration

Ania Wilczynska 1 collaboration

Sarah L Gillen 1 collaboration

Tobias Schmidt 1 collaboration

Hedda A Meijer 1 collaboration

Rebekah Jukes-Jones 1 collaboration

Claudia Langlais 1 collaboration

Wei-Ting Lu 1 collaboration

Jack D Godfrey 1 collaboration

Benjamin R Hawley 1 collaboration

Kelly Hodge 1 collaboration

Sara Zanivan 1 collaboration

Kelvin Cain 1 collaboration

Thorsten H Ecke 1 collaboration

Mikolaj Scislowski 1 collaboration

Mari Saura 1 collaboration

Steffen Hallmann 1 collaboration

Stefan Koch 1 collaboration

Sari Vuolle 1 collaboration

Bryce Dennis 1 collaboration

Lianbo Li 1 collaboration

Kenneth D Westover 1 collaboration

Niklas Vello 1 collaboration

Anita Komulainen 1 collaboration

Markku Syrjänpää 1 collaboration

Sakari Kulmala 1 collaboration

Maria Abreu-Blanco 1 collaboration

Matthew Holderfield 1 collaboration

Ahmadreza Masoumi 1 collaboration

Katri Lundell 1 collaboration

Arto Liljeblad 1 collaboration

Keelan Guiley 1 collaboration

Shizhong Dai 1 collaboration

Qinheng Zheng 1 collaboration

Lawrence Zhu 1 collaboration

Kevan M Shokat 1 collaboration

Allison Champagne 1 collaboration

Jinying Ning 1 collaboration

Andrew G Stephen 1 collaboration

Feng Hao 1 collaboration

Tatu Pantsar 1 collaboration

Jelena Jakovleva 1 collaboration

Leena Mattsson 1 collaboration

Moona Miettinen 1 collaboration

Mika Lastusaari 1 collaboration

Ganesh Babu Manoharan 1 collaboration

Daniel Abankwa 1 collaboration

Iraida Sharina 1 collaboration

Emil Martin 1 collaboration

Pinja Jalkanen 1 collaboration

Petri Susi 1 collaboration

Vesa Hytönen 1 collaboration

Minna Hankaniemi 1 collaboration

Seppo Ylä-Herttuala 1 collaboration

Laura Kakkola 1 collaboration

Markus Peurla 1 collaboration

Titta Yli-Hollo 1 collaboration

Sho Tabata 1 collaboration

Yuki Fujii 1 collaboration

Iida Vuorinen 1 collaboration

Aki Ogawa-Iio 1 collaboration

Akiyoshi Hirayama 1 collaboration

Tomoyoshi Soga 1 collaboration

Atsuo T Sasaki 1 collaboration