Kaare V Grunddal

Affiliations

Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Panum Institute, 2200 Copenhagen, Denmark.
Department of Medicine, University of California San Diego, La Jolla, CA 92037, USA.

Publications (15)

Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice.

Endocrinology

Avec: Kaare V Grunddal , Elisa P Jensen , Cathrine Ørskov , Daniel B Andersen , Johanne A Windeløv , Steen Seier Poulsen , Mette M Rosenkilde , Lotte Bjerre Knudsen , Charles Pyke , Jens J Holst

Development of a bispecific immune engager using a recombinant malaria protein.

Cell death & disease

Avec: Mie A Nordmaj , Morgan E Roberts , Emilie S Sachse , Robert Dagil , Anne Poder Andersen , Nanna Skeltved , Kaare V Grunddal , Sayit Mahmut Erdoğan , Swati Choudhary , Tobias Gustsavsson , Maj Sofie Ørum-Madsen , Igor Moskalev , Weihua Tian , Zhang Yang , Thomas M Clausen , Thor G Theander , Mads Daugaard , Morten A Nielsen , Ali Salanti

Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice.

American journal of physiology. Endocrinology and metabolism

Avec: Sara L Jepsen , Kaare V Grunddal , Nicolai J Wewer Albrechtsen , Maja S Engelstoft , Maria B N Gabe , Elisa P Jensen , Cathrine Ørskov , Steen S Poulsen , Mette M Rosenkilde , Jens Pedersen , Fiona M Gribble , Frank Reimann , Carolyn F Deacon , Thue W Schwartz , Andreas D Christ , Rainer E Martin , Jens J Holst

Bone-marrow macrophage-derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair.

Nature cardiovascular research

Avec: Sivakumar Ramadoss , Juan Qin , Bo Tao , Nathan E Thomas , Edward Cao , Rimao Wu , Daniel R Sandoval , Ann Piermatteo , Kaare V Grunddal , Feiyang Ma , Shen Li , Baiming Sun , Yonggang Zhou , Jijun Wan , Matteo Pellegrini , Birgitte Holst , Aldons J Lusis , Philip L S M Gordts , Arjun Deb

Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine.

International journal of obesity (2005)

Avec: Ida M Modvig , Daniel B Andersen , Kaare V Grunddal , Rune E Kuhre , Christoffer Martinussen , Charlotte B Christiansen , Cathrine Ørskov , Pierre Larraufie , Richard G Kay , Frank Reimann , Fiona M Gribble , Bolette Hartmann , Kirstine N Bojsen-Møller , Sten Madsbad , Nicolai J Wewer Albrechtsen , Jens J Holst

Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway.

Diabetes

Avec: Cecilia Ratner , Zhenyan He , Kaare V Grunddal , Louise J Skov , Bolette Hartmann , Fa Zhang , Annette Feuchtinger , Anette Bjerregaard , Christina Christoffersen , Matthias H Tschöp , Brian Finan , Richard D DiMarchi , Gina M Leinninger , Kevin W Williams , Christoffer Clemmensen , Birgitte Holst

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.

bioRxiv : the preprint server for biology

Avec: Daniel R Sandoval , Thomas Mandel Clausen , Chelsea Nora , Adam P Cribbs , Andrea Denardo , Alex E Clark , Aaron F Garretson , Joanna K C Coker , Anoop Narayanan , Sydney A Majowicz , Martin Philpott , Catrine Johansson , James E Dunford , Charlotte B Spliid , Gregory J Golden , N Connor Payne , Mark A Tye , Cameron J Nowell , Eric R Griffis , Ann Piermatteo , Kaare V Grunddal , Thibault Alle , Jason A Magida , Blake M Hauser , Jared Feldman , Timothy M Caradonna , Yuan Pu , Xin Yin , Rachael N McVicar , Elizabeth M Kwong , Ryan J Weiss , Michael Downes , Sotirios Tsimikas , Aaron G Smidt , Carlo Ballatore , Karsten Zengler , Ron M Evans , Sumit K Chanda , Ben A Croker , Sandra L Leibel , Joyce Jose , Ralph Mazitschek , Udo Oppermann , Jeffrey D Esko , Aaron F Carlin , Philip L S M Gordts

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist.

Molecular metabolism

Avec: Kaare V Grunddal , Thi A Diep , Natalia Petersen , Iain R Tough , Louise J Skov , Lingzhi Liu , Jesse A Buijink , Franziska Mende , Chunyu Jin , Sara L Jepsen , Louis M E Sørensen , Michael P Achiam , Rune B Strandby , Anders Bach , Bolette Hartmann , Thomas M Frimurer , Siv A Hjorth , Michel Bouvier , Helen Cox , Birgitte Holst

Decreased number of colonic tuft cells in quiescent ulcerative colitis patients.

European journal of gastroenterology & hepatology

Avec: Sebastian Kjærgaard , Thorbjørn S R Jensen , Ulrike R Feddersen , Niels Bindslev , Kaare V Grunddal , Steen S Poulsen , Hanne B Rasmussen , Esben Budtz-Jørgensen , Mark Berner-Hansen

Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Kunio Kawanishi , Joanna K Coker , Kaare V Grunddal , Chirag Dhar , Jason Hsiao , Karsten Zengler , Nissi Varki , Ajit Varki , Philip L S M Gordts

Actions of glucagon-like peptide-1 receptor ligands in the gut.

British journal of pharmacology

Avec: Jens Juul Holst , Daniel Bjørklund Andersen , Kaare Villum Grunddal

Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice.

Endocrinology

Avec: Daniel B Andersen , Kaare V Grunddal , Jens Pedersen , Rune E Kuhre , Mari L Lund , Jens J Holst , Cathrine Ørskov

Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells.

Molecular metabolism

Avec: Kaare V Grunddal , Sarah Tonack , Kristoffer L Egerod , Jonathan James Thompson , Natalia Petersen , Maja S Engelstoft , Constance Vagne , Céline Keime , Gérard Gradwohl , Stefan Offermanns , Thue W Schwartz

Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats.

Diabetologia

Avec: Kaare V Grunddal , Samuel A J Trammell , Cecilie Bæch-Laursen , Daniel B Andersen , Stella F S Xu , Helle Andersen , Matthew P Gillum , Seyed M Ghiasi , Ivana Novak , Björn Tyrberg , Chien Li , Mette M Rosenkilde , Bolette Hartmann , Jens J Holst , Rune E Kuhre

The human milk oligosaccharide 3'sialyllactose reduces low-grade inflammation and atherosclerosis development in mice.

JCI insight

Avec: Ariane R Pessentheiner , Nathanael J Spann , Chloe A Autran , Tae Gyu Oh , Kaare V Grunddal , Joanna Kc Coker , Chelsea D Painter , Bastian Ramms , Austin Wt Chiang , Chen-Yi Wang , Jason Hsiao , Yiwen Wang , Anthony Quach , Laela M Booshehri , Alexandra Hammond , Chiara Tognaccini , Joanna Latasiewicz , Lisa Willemsen , Karsten Zengler , Menno Pj de Winther , Hal M Hoffman , Martin Philpott , Adam P Cribbs , Udo Oppermann , Nathan E Lewis , Joseph L Witztum , Ruth Yu , Annette R Atkins , Michael Downes , Ron M Evans , Christopher K Glass , Lars Bode , Philip Lsm Gordts

Réseau de co-auteurs

Jens J Holst 5 collaborations

Cathrine Ørskov 4 collaborations

Daniel B Andersen 4 collaborations

Bolette Hartmann 4 collaborations

Mette M Rosenkilde 3 collaborations

Birgitte Holst 3 collaborations

Philip L S M Gordts 3 collaborations

Rune E Kuhre 3 collaborations

Karsten Zengler 3 collaborations

Elisa P Jensen 2 collaborations

Sara L Jepsen 2 collaborations

Nicolai J Wewer Albrechtsen 2 collaborations

Maja S Engelstoft 2 collaborations

Steen S Poulsen 2 collaborations

Jens Pedersen 2 collaborations

Fiona M Gribble 2 collaborations

Frank Reimann 2 collaborations

Thue W Schwartz 2 collaborations

Daniel R Sandoval 2 collaborations

Ann Piermatteo 2 collaborations

Louise J Skov 2 collaborations

Adam P Cribbs 2 collaborations

Martin Philpott 2 collaborations

Michael Downes 2 collaborations

Ron M Evans 2 collaborations

Udo Oppermann 2 collaborations

Natalia Petersen 2 collaborations

Jason Hsiao 2 collaborations

Johanne A Windeløv 1 collaboration

Steen Seier Poulsen 1 collaboration

Lotte Bjerre Knudsen 1 collaboration

Charles Pyke 1 collaboration

Mie A Nordmaj 1 collaboration

Morgan E Roberts 1 collaboration

Emilie S Sachse 1 collaboration

Robert Dagil 1 collaboration

Anne Poder Andersen 1 collaboration

Nanna Skeltved 1 collaboration

Sayit Mahmut Erdoğan 1 collaboration

Swati Choudhary 1 collaboration

Tobias Gustsavsson 1 collaboration

Maj Sofie Ørum-Madsen 1 collaboration

Igor Moskalev 1 collaboration

Weihua Tian 1 collaboration

Zhang Yang 1 collaboration

Thomas M Clausen 1 collaboration

Thor G Theander 1 collaboration

Mads Daugaard 1 collaboration

Morten A Nielsen 1 collaboration

Ali Salanti 1 collaboration

Maria B N Gabe 1 collaboration

Carolyn F Deacon 1 collaboration

Andreas D Christ 1 collaboration

Rainer E Martin 1 collaboration

Sivakumar Ramadoss 1 collaboration

Juan Qin 1 collaboration

Bo Tao 1 collaboration

Nathan E Thomas 1 collaboration

Edward Cao 1 collaboration

Rimao Wu 1 collaboration

Feiyang Ma 1 collaboration

Shen Li 1 collaboration

Baiming Sun 1 collaboration

Yonggang Zhou 1 collaboration

Jijun Wan 1 collaboration

Matteo Pellegrini 1 collaboration

Aldons J Lusis 1 collaboration

Arjun Deb 1 collaboration

Ida M Modvig 1 collaboration

Christoffer Martinussen 1 collaboration

Charlotte B Christiansen 1 collaboration

Pierre Larraufie 1 collaboration

Richard G Kay 1 collaboration

Kirstine N Bojsen-Møller 1 collaboration

Sten Madsbad 1 collaboration

Cecilia Ratner 1 collaboration

Zhenyan He 1 collaboration

Fa Zhang 1 collaboration

Annette Feuchtinger 1 collaboration

Anette Bjerregaard 1 collaboration

Christina Christoffersen 1 collaboration

Matthias H Tschöp 1 collaboration

Brian Finan 1 collaboration

Richard D DiMarchi 1 collaboration

Gina M Leinninger 1 collaboration

Kevin W Williams 1 collaboration

Christoffer Clemmensen 1 collaboration

Thomas Mandel Clausen 1 collaboration

Chelsea Nora 1 collaboration

Andrea Denardo 1 collaboration

Alex E Clark 1 collaboration

Aaron F Garretson 1 collaboration

Joanna K C Coker 1 collaboration

Anoop Narayanan 1 collaboration

Sydney A Majowicz 1 collaboration

Catrine Johansson 1 collaboration

James E Dunford 1 collaboration

Charlotte B Spliid 1 collaboration

Gregory J Golden 1 collaboration

N Connor Payne 1 collaboration

Mark A Tye 1 collaboration

Cameron J Nowell 1 collaboration

Eric R Griffis 1 collaboration

Thibault Alle 1 collaboration

Jason A Magida 1 collaboration

Blake M Hauser 1 collaboration

Jared Feldman 1 collaboration

Timothy M Caradonna 1 collaboration

Yuan Pu 1 collaboration

Xin Yin 1 collaboration

Rachael N McVicar 1 collaboration

Elizabeth M Kwong 1 collaboration

Ryan J Weiss 1 collaboration

Sotirios Tsimikas 1 collaboration

Aaron G Smidt 1 collaboration

Carlo Ballatore 1 collaboration

Sumit K Chanda 1 collaboration

Ben A Croker 1 collaboration

Sandra L Leibel 1 collaboration

Joyce Jose 1 collaboration

Ralph Mazitschek 1 collaboration

Jeffrey D Esko 1 collaboration

Aaron F Carlin 1 collaboration

Thi A Diep 1 collaboration

Iain R Tough 1 collaboration

Lingzhi Liu 1 collaboration

Jesse A Buijink 1 collaboration

Franziska Mende 1 collaboration

Chunyu Jin 1 collaboration

Louis M E Sørensen 1 collaboration

Michael P Achiam 1 collaboration

Rune B Strandby 1 collaboration

Anders Bach 1 collaboration

Thomas M Frimurer 1 collaboration

Siv A Hjorth 1 collaboration

Michel Bouvier 1 collaboration

Helen Cox 1 collaboration

Sebastian Kjærgaard 1 collaboration

Thorbjørn S R Jensen 1 collaboration

Ulrike R Feddersen 1 collaboration

Niels Bindslev 1 collaboration

Hanne B Rasmussen 1 collaboration

Esben Budtz-Jørgensen 1 collaboration

Mark Berner-Hansen 1 collaboration

Kunio Kawanishi 1 collaboration

Joanna K Coker 1 collaboration

Chirag Dhar 1 collaboration

Nissi Varki 1 collaboration

Ajit Varki 1 collaboration

Jens Juul Holst 1 collaboration

Daniel Bjørklund Andersen 1 collaboration

Kaare Villum Grunddal 1 collaboration

Mari L Lund 1 collaboration

Sarah Tonack 1 collaboration

Kristoffer L Egerod 1 collaboration

Jonathan James Thompson 1 collaboration

Constance Vagne 1 collaboration

Céline Keime 1 collaboration

Gérard Gradwohl 1 collaboration

Stefan Offermanns 1 collaboration

Samuel A J Trammell 1 collaboration

Cecilie Bæch-Laursen 1 collaboration

Stella F S Xu 1 collaboration

Helle Andersen 1 collaboration

Matthew P Gillum 1 collaboration

Seyed M Ghiasi 1 collaboration

Ivana Novak 1 collaboration

Björn Tyrberg 1 collaboration

Chien Li 1 collaboration

Ariane R Pessentheiner 1 collaboration

Nathanael J Spann 1 collaboration

Chloe A Autran 1 collaboration

Tae Gyu Oh 1 collaboration

Joanna Kc Coker 1 collaboration

Chelsea D Painter 1 collaboration

Bastian Ramms 1 collaboration

Austin Wt Chiang 1 collaboration

Chen-Yi Wang 1 collaboration

Yiwen Wang 1 collaboration

Anthony Quach 1 collaboration

Laela M Booshehri 1 collaboration

Alexandra Hammond 1 collaboration

Chiara Tognaccini 1 collaboration

Joanna Latasiewicz 1 collaboration

Lisa Willemsen 1 collaboration

Menno Pj de Winther 1 collaboration

Hal M Hoffman 1 collaboration

Nathan E Lewis 1 collaboration

Joseph L Witztum 1 collaboration

Ruth Yu 1 collaboration

Annette R Atkins 1 collaboration

Christopher K Glass 1 collaboration

Lars Bode 1 collaboration

Philip Lsm Gordts 1 collaboration