Justin Langerman

Affiliations

Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Publications (17)

A Deep Learning Approach for Segmentation, Classification, and Visualization of 3-D High-Frequency Ultrasound Images of Mouse Embryos.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Avec: Ziming Qiu , Tongda Xu , Jack Langerman , William Das , Chuiyu Wang , Nitin Nair , Orlando Aristizabal , Jonathan Mamou , Daniel H Turnbull , Jeffrey A Ketterling , Yao Wang

Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.

Nature medicine

Avec: Gianni Carraro , Justin Langerman , Shan Sabri , Zareeb Lorenzana , Arunima Purkayastha , Guangzhu Zhang , Bindu Konda , Cody J Aros , Ben A Calvert , Aleks Szymaniak , Emily Wilson , Michael Mulligan , Priyanka Bhatt , Junjie Lu , Preethi Vijayaraj , Changfu Yao , David W Shia , Andrew J Lund , Edo Israely , Tammy M Rickabaugh , Jason Ernst , Martin Mense , Scott H Randell , Eszter K Vladar , Amy L Ryan , Kathrin Plath , John E Mahoney , Barry R Stripp , Brigitte N Gomperts

Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis.

Stem cell reports

Avec: Thomas Allison , Justin Langerman , Shan Sabri , Marcos Otero-Garcia , Andrew Lund , John Huang , Xiaofei Wei , Ranmal A Samarasinghe , Damon Polioudakis , Istvan Mody , Inma Cobos , Bennett G Novitch , Daniel H Geschwind , Kathrin Plath , William E Lowry

Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity.

Cell reports

Avec: Prabhat K Purbey , Joowon Seo , Manash K Paul , Keisuke S Iwamoto , Allison E Daly , An-Chieh Feng , Ameya S Champhekar , Justin Langerman , Katie M Campbell , Dörthe Schaue , William H McBride , Steven M Dubinett , Antoni Ribas , Stephen T Smale , Philip O Scumpia

Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells.

Stem cell reports

Avec: Justin Langerman , David Lopez , Matteo Pellegrini , Stephen T Smale

SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.

Nature communications

Avec: Peter J Mullen , Gustavo Garcia , Arunima Purkayastha , Nedas Matulionis , Ernst W Schmid , Milica Momcilovic , Chandani Sen , Justin Langerman , Arunachalam Ramaiah , David B Shackelford , Robert Damoiseaux , Samuel W French , Kathrin Plath , Brigitte N Gomperts , Vaithilingaraja Arumugaswami , Heather R Christofk

Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.

Cell stem cell

Avec: Arunima Purkayastha , Chandani Sen , Gustavo Garcia , Justin Langerman , David W Shia , Luisa K Meneses , Preethi Vijayaraj , Abdo Durra , Caroline R Koloff , Delilah R Freund , Justin Chi , Tammy M Rickabaugh , Apoorva Mulay , Bindu Konda , Myung S Sim , Barry R Stripp , Kathrin Plath , Vaithilingaraja Arumugaswami , Brigitte N Gomperts

Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis.

bioRxiv : the preprint server for biology

Avec: Rachana R Chandran , Preethi Vijayaraj , Rolando Garcia-Milian , Jade King , Kristen Castillo , Liang Chen , Yumi Kwon , Sarai William , Tammy M Rickabaugh , Justin Langerman , Woosuk Choi , Chandani Sen , Jacelyn E P Lever , Qian Li , Nikoleta Pavelkova , Erin J Plosa , Steven M Rowe , Kathrin Plath , Geremy Clair , Brigitte N Gomperts

Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jack Freeland , Maria Muñoz , Edmond O'Donnell , Justin Langerman , Morgan Darrow , Jessica Bergonio , Julissa Suarez-Navarro , Steven Thorpe , Robert Canter , R Lor Randall , Kathrin Plath , Kermit L Carraway , Owen N Witte , Thomas G Graeber , Janai R Carr-Ascher

A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.

Cell stem cell

Avec: Haibin Xi , Justin Langerman , Shan Sabri , Peggie Chien , Courtney S Young , Shahab Younesi , Michael Hicks , Karen Gonzalez , Wakana Fujiwara , Julia Marzi , Simone Liebscher , Melissa Spencer , Ben Van Handel , Denis Evseenko , Katja Schenke-Layland , Kathrin Plath , April D Pyle

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response.

bioRxiv : the preprint server for biology

Avec: Arunima Purkayastha , Chandani Sen , Gustavo Garcia , Justin Langerman , Preethi Vijayaraj , David W Shia , Luisa K Meneses , Tammy M Rickabaugh , A Mulay , B Konda , Myung S Sim , Barry R Stripp , Kathrin Plath , Vaithilingaraja Arumugaswami , Brigitte N Gomperts

DEEP MOUSE: AN END-TO-END AUTO-CONTEXT REFINEMENT FRAMEWORK FOR BRAIN VENTRICLE & BODY SEGMENTATION IN EMBRYONIC MICE ULTRASOUND VOLUMES.

Proceedings. IEEE International Symposium on Biomedical Imaging

Avec: Tongda Xu , Ziming Qiu , William Das , Chuiyu Wang , Jack Langerman , Nitin Nair , Orlando Aristizábal , Jonathan Mamou , Daniel H Turnbull , Jeffrey A Ketterling , Yao Wang

Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells.

Genes & development

Avec: Jerry Hung-Hao Lo , Miguel Edwards , Justin Langerman , Rupa Sridharan , Kathrin Plath , Stephen T Smale

A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation.

Neuron

Avec: Damon Polioudakis , Luis de la Torre-Ubieta , Justin Langerman , Andrew G Elkins , Xu Shi , Jason L Stein , Celine K Vuong , Susanne Nichterwitz , Melinda Gevorgian , Carli K Opland , Daning Lu , William Connell , Elizabeth K Ruzzo , Jennifer K Lowe , Tarik Hadzic , Flora I Hinz , Shan Sabri , William E Lowry , Mark B Gerstein , Kathrin Plath , Daniel H Geschwind

Associating growth factor secretions and transcriptomes of single cells in nanovials using SEC-seq.

Nature nanotechnology

Avec: Shreya Udani , Justin Langerman , Doyeon Koo , Sevana Baghdasarian , Brian Cheng , Simran Kang , Citradewi Soemardy , Joseph de Rutte , Kathrin Plath , Dino Di Carlo

Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells.

bioRxiv : the preprint server for biology

Avec: Shreya Udani , Justin Langerman , Doyeon Koo , Sevana Baghdasarian , Brian Cheng , Simran Kang , Citradewi Soemardy , Joseph de Rutte , Kathrin Plath , Dino Di Carlo

H3K36 methylation maintains cell identity by regulating opposing lineage programmes.

Nature cell biology

Avec: Michael S Hoetker , Masaki Yagi , Bruno Di Stefano , Justin Langerman , Simona Cristea , Lai Ping Wong , Aaron J Huebner , Jocelyn Charlton , Weixian Deng , Chuck Haggerty , Ruslan I Sadreyev , Alexander Meissner , Franziska Michor , Kathrin Plath , Konrad Hochedlinger

Réseau de co-auteurs

Kathrin Plath 13 collaborations

Brigitte N Gomperts 5 collaborations

Shan Sabri 4 collaborations

Arunima Purkayastha 4 collaborations

Preethi Vijayaraj 4 collaborations

Tammy M Rickabaugh 4 collaborations

Chandani Sen 4 collaborations

David W Shia 3 collaborations

Barry R Stripp 3 collaborations

Stephen T Smale 3 collaborations

Gustavo Garcia 3 collaborations

Vaithilingaraja Arumugaswami 3 collaborations

Ziming Qiu 2 collaborations

Tongda Xu 2 collaborations

Jack Langerman 2 collaborations

William Das 2 collaborations

Chuiyu Wang 2 collaborations

Nitin Nair 2 collaborations

Jonathan Mamou 2 collaborations

Daniel H Turnbull 2 collaborations

Jeffrey A Ketterling 2 collaborations

Yao Wang 2 collaborations

Bindu Konda 2 collaborations

Damon Polioudakis 2 collaborations

Daniel H Geschwind 2 collaborations

William E Lowry 2 collaborations

Luisa K Meneses 2 collaborations

Myung S Sim 2 collaborations

Shreya Udani 2 collaborations

Doyeon Koo 2 collaborations

Sevana Baghdasarian 2 collaborations

Brian Cheng 2 collaborations

Simran Kang 2 collaborations

Citradewi Soemardy 2 collaborations

Joseph de Rutte 2 collaborations

Dino Di Carlo 2 collaborations

Orlando Aristizabal 1 collaboration

Gianni Carraro 1 collaboration

Zareeb Lorenzana 1 collaboration

Guangzhu Zhang 1 collaboration

Cody J Aros 1 collaboration

Ben A Calvert 1 collaboration

Aleks Szymaniak 1 collaboration

Emily Wilson 1 collaboration

Michael Mulligan 1 collaboration

Priyanka Bhatt 1 collaboration

Junjie Lu 1 collaboration

Changfu Yao 1 collaboration

Andrew J Lund 1 collaboration

Edo Israely 1 collaboration

Jason Ernst 1 collaboration

Martin Mense 1 collaboration

Scott H Randell 1 collaboration

Eszter K Vladar 1 collaboration

Amy L Ryan 1 collaboration

John E Mahoney 1 collaboration

Thomas Allison 1 collaboration

Marcos Otero-Garcia 1 collaboration

Andrew Lund 1 collaboration

John Huang 1 collaboration

Xiaofei Wei 1 collaboration

Ranmal A Samarasinghe 1 collaboration

Istvan Mody 1 collaboration

Inma Cobos 1 collaboration

Bennett G Novitch 1 collaboration

Prabhat K Purbey 1 collaboration

Joowon Seo 1 collaboration

Manash K Paul 1 collaboration

Keisuke S Iwamoto 1 collaboration

Allison E Daly 1 collaboration

An-Chieh Feng 1 collaboration

Ameya S Champhekar 1 collaboration

Katie M Campbell 1 collaboration

Dörthe Schaue 1 collaboration

William H McBride 1 collaboration

Steven M Dubinett 1 collaboration

Antoni Ribas 1 collaboration

Philip O Scumpia 1 collaboration

David Lopez 1 collaboration

Matteo Pellegrini 1 collaboration

Peter J Mullen 1 collaboration

Nedas Matulionis 1 collaboration

Ernst W Schmid 1 collaboration

Milica Momcilovic 1 collaboration

Arunachalam Ramaiah 1 collaboration

David B Shackelford 1 collaboration

Robert Damoiseaux 1 collaboration

Samuel W French 1 collaboration

Heather R Christofk 1 collaboration

Abdo Durra 1 collaboration

Caroline R Koloff 1 collaboration

Delilah R Freund 1 collaboration

Justin Chi 1 collaboration

Apoorva Mulay 1 collaboration

Rachana R Chandran 1 collaboration

Rolando Garcia-Milian 1 collaboration

Jade King 1 collaboration

Kristen Castillo 1 collaboration

Liang Chen 1 collaboration

Yumi Kwon 1 collaboration

Sarai William 1 collaboration

Woosuk Choi 1 collaboration

Jacelyn E P Lever 1 collaboration

Qian Li 1 collaboration

Nikoleta Pavelkova 1 collaboration

Erin J Plosa 1 collaboration

Steven M Rowe 1 collaboration

Geremy Clair 1 collaboration

Jack Freeland 1 collaboration

Maria Muñoz 1 collaboration

Edmond O'Donnell 1 collaboration

Morgan Darrow 1 collaboration

Jessica Bergonio 1 collaboration

Julissa Suarez-Navarro 1 collaboration

Steven Thorpe 1 collaboration

Robert Canter 1 collaboration

R Lor Randall 1 collaboration

Kermit L Carraway 1 collaboration

Owen N Witte 1 collaboration

Thomas G Graeber 1 collaboration

Janai R Carr-Ascher 1 collaboration

Haibin Xi 1 collaboration

Peggie Chien 1 collaboration

Courtney S Young 1 collaboration

Shahab Younesi 1 collaboration

Michael Hicks 1 collaboration

Karen Gonzalez 1 collaboration

Wakana Fujiwara 1 collaboration

Julia Marzi 1 collaboration

Simone Liebscher 1 collaboration

Melissa Spencer 1 collaboration

Ben Van Handel 1 collaboration

Denis Evseenko 1 collaboration

Katja Schenke-Layland 1 collaboration

April D Pyle 1 collaboration

A Mulay 1 collaboration

B Konda 1 collaboration

Orlando Aristizábal 1 collaboration

Jerry Hung-Hao Lo 1 collaboration

Miguel Edwards 1 collaboration

Rupa Sridharan 1 collaboration

Luis de la Torre-Ubieta 1 collaboration

Andrew G Elkins 1 collaboration

Xu Shi 1 collaboration

Jason L Stein 1 collaboration

Celine K Vuong 1 collaboration

Susanne Nichterwitz 1 collaboration

Melinda Gevorgian 1 collaboration

Carli K Opland 1 collaboration

Daning Lu 1 collaboration

William Connell 1 collaboration

Elizabeth K Ruzzo 1 collaboration

Jennifer K Lowe 1 collaboration

Tarik Hadzic 1 collaboration

Flora I Hinz 1 collaboration

Mark B Gerstein 1 collaboration

Michael S Hoetker 1 collaboration

Masaki Yagi 1 collaboration

Bruno Di Stefano 1 collaboration

Simona Cristea 1 collaboration

Lai Ping Wong 1 collaboration

Aaron J Huebner 1 collaboration

Jocelyn Charlton 1 collaboration

Weixian Deng 1 collaboration

Chuck Haggerty 1 collaboration

Ruslan I Sadreyev 1 collaboration

Alexander Meissner 1 collaboration

Franziska Michor 1 collaboration

Konrad Hochedlinger 1 collaboration