Johnathan R Whetstine

Affiliations

Massachusetts General Hospital Cancer Center and Harvard Medical School Department of Medicine, 13th Street Bldg. 149, Charlestown, MA 02129, USA; Institute for Cancer Research, Fox Chase Cancer Center, 333 Cottman Avenue West 260, Philadelphia, PA 19111, USA; Cancer Epigenetics Institute, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.

Publications (13)

Computational workflow for integrative analyses of DNA replication timing, epigenomic, and transcriptomic data.

STAR protocols

Avec: Fei Ji , Capucine Van Rechem , Johnathan R Whetstine , Ruslan I Sadreyev

Histone Lysine Methylation Dynamics Control

Cancer discovery

Avec: Thomas L Clarke , Ran Tang , Damayanti Chakraborty , Capucine Van Rechem , Fei Ji , Sweta Mishra , Anqi Ma , H Ümit Kaniskan , Jian Jin , Michael S Lawrence , Ruslan I Sadreyev , Johnathan R Whetstine

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans.

Scientific reports

Avec: Tao Zhang , Cheng Ni , Cheng Li , Pan Lu , Dan Chen , Yuanlin Dong , Johnathan R Whetstine , Yiying Zhang , Zhongcong Xie

Collective regulation of chromatin modifications predicts replication timing during cell cycle.

Cell reports

Avec: Capucine Van Rechem , Fei Ji , Damayanti Chakraborty , Joshua C Black , Ruslan I Sadreyev , Johnathan R Whetstine

Protocol to isolate cells in four stages of S phase for high-resolution replication-timing sequencing.

STAR protocols

Avec: Johnathan R Whetstine , Capucine Van Rechem

The lysine demethylase KDM4A controls the cell-cycle expression of replicative canonical histone genes.

Biochimica et biophysica acta. Gene regulatory mechanisms

Avec: Capucine Van Rechem , Fei Ji , Sweta Mishra , Damayanti Chakraborty , Sedona E Murphy , Megan E Dillingham , Ruslan I Sadreyev , Johnathan R Whetstine

DNA replication fork speed underlies cell fate changes and promotes reprogramming.

Nature genetics

Avec: Tsunetoshi Nakatani , Jiangwei Lin , Fei Ji , Andreas Ettinger , Julien Pontabry , Mikiko Tokoro , Luis Altamirano-Pacheco , Jonathan Fiorentino , Elmir Mahammadov , Yu Hatano , Capucine Van Rechem , Damayanti Chakraborty , Elias R Ruiz-Morales , Paola Y Arguello Pascualli , Antonio Scialdone , Kazuo Yamagata , Johnathan R Whetstine , Ruslan I Sadreyev , Maria-Elena Torres-Padilla

Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.

Cell

Avec: Zach H Gray , Damayanti Chakraborty , Reuben R Duttweiler , Gulnaz D Alekbaeva , Sedona E Murphy , Kashish Chetal , Fei Ji , Benjamin I Ferman , Madison A Honer , Zhentian Wang , Cynthia Myers , Renhong Sun , H Ümit Kaniskan , Monika Maria Toma , Elena A Bondarenko , John N Santoro , Christopher Miranda , Megan E Dillingham , Ran Tang , Or Gozani , Jian Jin , Tomasz Skorski , Cihangir Duy , Hayan Lee , Ruslan I Sadreyev , Johnathan R Whetstine

The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.

Molecular cell

Avec: Jean-Pierre Etchegaray , Lei Zhong , Catherine Li , Telmo Henriques , Eileen Ablondi , Tomoyoshi Nakadai , Capucine Van Rechem , Christina Ferrer , Kenneth N Ross , Jee-Eun Choi , Ann Samarakkody , Fei Ji , Andrew Chang , Ruslan I Sadreyev , Sridhar Ramaswamy , Sergei Nechaev , Johnathan R Whetstine , Robert G Roeder , Karen Adelman , Alon Goren , Raul Mostoslavsky

PRC2 Plays Red Light, Green Light with MHC-I and CD8

Cancer cell

Avec: Johnathan R Whetstine

A cell-sorting-based protocol for cell cycle small-scale ChIP sequencing.

STAR protocols

Avec: Johnathan R Whetstine , Capucine Van Rechem

TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.

Gastroenterology

Avec: Rossella Tricarico , Jozef Madzo , Gabrielle Scher , Maya Cohen , Jaroslav Jelinek , Shinji Maegawa , Rajeswari Nagarathinam , Carly Scher , Wen-Chi Chang , Emmanuelle Nicolas , Michael Slifker , Yan Zhou , Karthik Devarajan , Kathy Q Cai , Tim Kwok , Pamela Nakajima , Jinfei Xu , Pietro Mancuso , Valentina Doneddu , Luigi Bagella , Riley Williams , Siddharth Balachandran , Nicholas Maskalenko , Kerry Campbell , Xueying Ma , Israel Cañadas , Julen Viana-Errasti , Victor Moreno , Laura Valle , Sergei Grivennikov , Iuliia Peshkova , Natalia Kurilenko , Aleksandra Mazitova , Ekaterina Koltsova , Hayan Lee , Martin Walsh , Reuben Duttweiler , Johnathan R Whetstine , Timothy J Yen , Jean-Pierre Issa , Alfonso Bellacosa

Epigenetic modulators provide a path to understanding disease and therapeutic opportunity.

Genes & development

Avec: Madison A Honer , Benjamin I Ferman , Zach H Gray , Elena A Bondarenko , Johnathan R Whetstine

Réseau de co-auteurs

Capucine Van Rechem 8 collaborations

Fei Ji 7 collaborations

Ruslan I Sadreyev 7 collaborations

Damayanti Chakraborty 5 collaborations

Ran Tang 2 collaborations

Sweta Mishra 2 collaborations

H Ümit Kaniskan 2 collaborations

Jian Jin 2 collaborations

Sedona E Murphy 2 collaborations

Megan E Dillingham 2 collaborations

Zach H Gray 2 collaborations

Benjamin I Ferman 2 collaborations

Madison A Honer 2 collaborations

Elena A Bondarenko 2 collaborations

Hayan Lee 2 collaborations

Thomas L Clarke 1 collaboration

Anqi Ma 1 collaboration

Michael S Lawrence 1 collaboration

Tao Zhang 1 collaboration

Cheng Ni 1 collaboration

Cheng Li 1 collaboration

Pan Lu 1 collaboration

Dan Chen 1 collaboration

Yuanlin Dong 1 collaboration

Yiying Zhang 1 collaboration

Zhongcong Xie 1 collaboration

Joshua C Black 1 collaboration

Tsunetoshi Nakatani 1 collaboration

Jiangwei Lin 1 collaboration

Andreas Ettinger 1 collaboration

Julien Pontabry 1 collaboration

Mikiko Tokoro 1 collaboration

Luis Altamirano-Pacheco 1 collaboration

Jonathan Fiorentino 1 collaboration

Elmir Mahammadov 1 collaboration

Yu Hatano 1 collaboration

Elias R Ruiz-Morales 1 collaboration

Paola Y Arguello Pascualli 1 collaboration

Antonio Scialdone 1 collaboration

Kazuo Yamagata 1 collaboration

Maria-Elena Torres-Padilla 1 collaboration

Reuben R Duttweiler 1 collaboration

Gulnaz D Alekbaeva 1 collaboration

Kashish Chetal 1 collaboration

Zhentian Wang 1 collaboration

Cynthia Myers 1 collaboration

Renhong Sun 1 collaboration

Monika Maria Toma 1 collaboration

John N Santoro 1 collaboration

Christopher Miranda 1 collaboration

Or Gozani 1 collaboration

Tomasz Skorski 1 collaboration

Cihangir Duy 1 collaboration

Jean-Pierre Etchegaray 1 collaboration

Lei Zhong 1 collaboration

Catherine Li 1 collaboration

Telmo Henriques 1 collaboration

Eileen Ablondi 1 collaboration

Tomoyoshi Nakadai 1 collaboration

Christina Ferrer 1 collaboration

Kenneth N Ross 1 collaboration

Jee-Eun Choi 1 collaboration

Ann Samarakkody 1 collaboration

Andrew Chang 1 collaboration

Sridhar Ramaswamy 1 collaboration

Sergei Nechaev 1 collaboration

Robert G Roeder 1 collaboration

Karen Adelman 1 collaboration

Alon Goren 1 collaboration

Raul Mostoslavsky 1 collaboration

Rossella Tricarico 1 collaboration

Jozef Madzo 1 collaboration

Gabrielle Scher 1 collaboration

Maya Cohen 1 collaboration

Jaroslav Jelinek 1 collaboration

Shinji Maegawa 1 collaboration

Rajeswari Nagarathinam 1 collaboration

Carly Scher 1 collaboration

Wen-Chi Chang 1 collaboration

Emmanuelle Nicolas 1 collaboration

Michael Slifker 1 collaboration

Yan Zhou 1 collaboration

Karthik Devarajan 1 collaboration

Kathy Q Cai 1 collaboration

Tim Kwok 1 collaboration

Pamela Nakajima 1 collaboration

Jinfei Xu 1 collaboration

Pietro Mancuso 1 collaboration

Valentina Doneddu 1 collaboration

Luigi Bagella 1 collaboration

Riley Williams 1 collaboration

Siddharth Balachandran 1 collaboration

Nicholas Maskalenko 1 collaboration

Kerry Campbell 1 collaboration

Xueying Ma 1 collaboration

Israel Cañadas 1 collaboration

Julen Viana-Errasti 1 collaboration

Victor Moreno 1 collaboration

Laura Valle 1 collaboration

Sergei Grivennikov 1 collaboration

Iuliia Peshkova 1 collaboration

Natalia Kurilenko 1 collaboration

Aleksandra Mazitova 1 collaboration

Ekaterina Koltsova 1 collaboration

Martin Walsh 1 collaboration

Reuben Duttweiler 1 collaboration

Timothy J Yen 1 collaboration

Jean-Pierre Issa 1 collaboration

Alfonso Bellacosa 1 collaboration