John Platig

Affiliations

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Harvard Medical School, Harvard University, Boston, MA, United States.

Publications (16)

Gene Targeting in Disease Networks.

Frontiers in genetics

Avec: Deborah Weighill , Marouen Ben Guebila , Kimberly Glass , John Platig , Jen Jen Yeh , John Quackenbush

Complex Traits Heritability is Highly Clustered in the eQTL Bipartite Network.

bioRxiv : the preprint server for biology

Avec: Katherine Stone , John Platig , John Quackenbush , Maud Fagny

Identification of an emphysema-associated genetic variant near

eLife

Avec: Margaret M Parker , Yuan Hao , Feng Guo , Betty Pham , Robert Chase , John Platig , Michael H Cho , Craig P Hersh , Victor J Thannickal , James Crapo , George Washko , Scott H Randell , Edwin K Silverman , Raúl San José Estépar , Xiaobo Zhou , Peter J Castaldi

Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis.

NPJ systems biology and applications

Avec: Albert T Young , Xavier Carette , Michaela Helmel , Hanno Steen , Robert N Husson , John Quackenbush , John Platig

GRAND: a database of gene regulatory network models across human conditions.

Nucleic acids research

Avec: Marouen Ben Guebila , Camila M Lopes-Ramos , Deborah Weighill , Abhijeet Rajendra Sonawane , Rebekka Burkholz , Behrouz Shamsaei , John Platig , Kimberly Glass , Marieke L Kuijjer , John Quackenbush

Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function.

British journal of cancer

Avec: Maud Fagny , John Platig , Marieke Lydia Kuijjer , Xihong Lin , John Quackenbush

Gene regulatory network inference as relaxed graph matching.

Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence

Avec: Deborah Weighill , Marouen Ben Guebila , Camila Lopes-Ramos , Kimberly Glass , John Quackenbush , John Platig , Rebekka Burkholz

Predicting genotype-specific gene regulatory networks.

Genome research

Avec: Deborah Weighill , Marouen Ben Guebila , Kimberly Glass , John Quackenbush , John Platig

Partial correlation network analysis identifies coordinated gene expression within a regional cluster of COPD genome-wide association signals.

PLoS computational biology

Avec: Michele Gentili , Kimberly Glass , Enrico Maiorino , Brian D Hobbs , Zhonghui Xu , Peter J Castaldi , Michael H Cho , Craig P Hersh , Dandi Qiao , Jarrett D Morrow , Vincent J Carey , John Platig , Edwin K Silverman

Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility.

PLoS pathogens

Avec: Jumei Zeng , John Platig , Tan-Yun Cheng , Saima Ahmed , Yara Skaf , Lakshmi-Prasad Potluri , Daniel Schwartz , Hanno Steen , D Branch Moody , Robert N Husson

Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues.

Cell reports

Avec: Camila M Lopes-Ramos , Cho-Yi Chen , Marieke L Kuijjer , Joseph N Paulson , Abhijeet R Sonawane , Maud Fagny , John Platig , Kimberly Glass , John Quackenbush , Dawn L DeMeo

Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease.

PLoS genetics

Avec: Lela Lackey , Aaztli Coria , Auyon J Ghosh , Phil Grayeski , Abigail Hatfield , Vijay Shankar , John Platig , Zhonghui Xu , Silvia B V Ramos , Edwin K Silverman , Victor E Ortega , Michael H Cho , Craig P Hersh , Brian D Hobbs , Peter Castaldi , Alain Laederach

Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation.

Genomics

Avec: Zhonghui Xu , John Platig , Sool Lee , Adel Boueiz , Rob Chase , Dhawal Jain , Andrew Gregory , Rahul Suryadevara , Seth Berman , Russell Bowler , Craig P Hersh , Alain Laederach , Peter J Castaldi , Auteur inconnu

Connectivity in eQTL networks dictates reproducibility and genomic properties.

Cell reports methods

Avec: Sheila M Gaynor , Maud Fagny , Xihong Lin , John Platig , John Quackenbush

Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes.

medRxiv : the preprint server for health sciences

Avec: Matthew Moll , Julian Hecker , John Platig , Jingzhou Zhang , Auyon J Ghosh , Katherine A Pratte , Rui-Sheng Wang , Davin Hill , Iain R Konigsberg , Joe W Chiles , Craig P Hersh , Peter J Castaldi , Kimberly Glass , Jennifer G Dy , Don D Sin , Ruth Tal-Singer , Majd Mouded , Stephen I Rennard , Gary P Anderson , Gregory L Kinney , Russell P Bowler , Jeffrey L Curtis , Merry-Lynn McDonald , Edwin K Silverman , Brian D Hobbs , Michael H Cho

The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks.

Genome biology

Avec: Marouen Ben Guebila , Tian Wang , Camila M Lopes-Ramos , Viola Fanfani , Des Weighill , Rebekka Burkholz , Daniel Schlauch , Joseph N Paulson , Michael Altenbuchinger , Katherine H Shutta , Abhijeet R Sonawane , James Lim , Genis Calderer , David G P van IJzendoorn , Daniel Morgan , Alessandro Marin , Cho-Yi Chen , Qi Song , Enakshi Saha , Dawn L DeMeo , Megha Padi , John Platig , Marieke L Kuijjer , Kimberly Glass , John Quackenbush

Réseau de co-auteurs

John Quackenbush 10 collaborations

Kimberly Glass 8 collaborations

Marouen Ben Guebila 5 collaborations

Craig P Hersh 5 collaborations

Deborah Weighill 4 collaborations

Maud Fagny 4 collaborations

Michael H Cho 4 collaborations

Edwin K Silverman 4 collaborations

Peter J Castaldi 4 collaborations

Camila M Lopes-Ramos 3 collaborations

Rebekka Burkholz 3 collaborations

Marieke L Kuijjer 3 collaborations

Brian D Hobbs 3 collaborations

Zhonghui Xu 3 collaborations

Hanno Steen 2 collaborations

Robert N Husson 2 collaborations

Xihong Lin 2 collaborations

Cho-Yi Chen 2 collaborations

Joseph N Paulson 2 collaborations

Abhijeet R Sonawane 2 collaborations

Dawn L DeMeo 2 collaborations

Auyon J Ghosh 2 collaborations

Alain Laederach 2 collaborations

Jen Jen Yeh 1 collaboration

Katherine Stone 1 collaboration

Margaret M Parker 1 collaboration

Yuan Hao 1 collaboration

Feng Guo 1 collaboration

Betty Pham 1 collaboration

Robert Chase 1 collaboration

Victor J Thannickal 1 collaboration

James Crapo 1 collaboration

George Washko 1 collaboration

Scott H Randell 1 collaboration

Raúl San José Estépar 1 collaboration

Xiaobo Zhou 1 collaboration

Albert T Young 1 collaboration

Xavier Carette 1 collaboration

Michaela Helmel 1 collaboration

Abhijeet Rajendra Sonawane 1 collaboration

Behrouz Shamsaei 1 collaboration

Marieke Lydia Kuijjer 1 collaboration

Camila Lopes-Ramos 1 collaboration

Michele Gentili 1 collaboration

Enrico Maiorino 1 collaboration

Dandi Qiao 1 collaboration

Jarrett D Morrow 1 collaboration

Vincent J Carey 1 collaboration

Jumei Zeng 1 collaboration

Tan-Yun Cheng 1 collaboration

Saima Ahmed 1 collaboration

Yara Skaf 1 collaboration

Lakshmi-Prasad Potluri 1 collaboration

Daniel Schwartz 1 collaboration

D Branch Moody 1 collaboration

Lela Lackey 1 collaboration

Aaztli Coria 1 collaboration

Phil Grayeski 1 collaboration

Abigail Hatfield 1 collaboration

Vijay Shankar 1 collaboration

Silvia B V Ramos 1 collaboration

Victor E Ortega 1 collaboration

Peter Castaldi 1 collaboration

Sool Lee 1 collaboration

Adel Boueiz 1 collaboration

Rob Chase 1 collaboration

Dhawal Jain 1 collaboration

Andrew Gregory 1 collaboration

Rahul Suryadevara 1 collaboration

Seth Berman 1 collaboration

Russell Bowler 1 collaboration

None None 1 collaboration

Sheila M Gaynor 1 collaboration

Matthew Moll 1 collaboration

Julian Hecker 1 collaboration

Jingzhou Zhang 1 collaboration

Katherine A Pratte 1 collaboration

Rui-Sheng Wang 1 collaboration

Davin Hill 1 collaboration

Iain R Konigsberg 1 collaboration

Joe W Chiles 1 collaboration

Jennifer G Dy 1 collaboration

Don D Sin 1 collaboration

Ruth Tal-Singer 1 collaboration

Majd Mouded 1 collaboration

Stephen I Rennard 1 collaboration

Gary P Anderson 1 collaboration

Gregory L Kinney 1 collaboration

Russell P Bowler 1 collaboration

Jeffrey L Curtis 1 collaboration

Merry-Lynn McDonald 1 collaboration

Tian Wang 1 collaboration

Viola Fanfani 1 collaboration

Des Weighill 1 collaboration

Daniel Schlauch 1 collaboration

Michael Altenbuchinger 1 collaboration

Katherine H Shutta 1 collaboration

James Lim 1 collaboration

Genis Calderer 1 collaboration

David G P van IJzendoorn 1 collaboration

Daniel Morgan 1 collaboration

Alessandro Marin 1 collaboration

Qi Song 1 collaboration

Enakshi Saha 1 collaboration

Megha Padi 1 collaboration