Jennifer M Luppino

Affiliations

Department of Genetics, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

ORCID: http://orcid.org/0000-0002-2078-7619

Publications (9)

Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes.

Nature genetics

Avec: Jennifer M Luppino , Daniel S Park , Son C Nguyen , Yemin Lan , Zhuxuan Xu , Rebecca Yunker , Eric F Joyce

Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome.

Cell

Avec: Thomas Malachowski , Keerthivasan Raanin Chandradoss , Ravi Boya , Linda Zhou , Ashley L Cook , Chuanbin Su , Kenneth Pham , Spencer A Haws , Ji Hun Kim , Han-Seul Ryu , Chunmin Ge , Jennifer M Luppino , Son C Nguyen , Katelyn R Titus , Wanfeng Gong , Owen Wallace , Eric F Joyce , Hao Wu , Luis Alejandro Rojas , Jennifer E Phillips-Cremins

High-throughput Oligopaint screen identifies druggable 3D genome regulators.

Nature

Avec: Daniel S Park , Son C Nguyen , Randi Isenhart , Parisha P Shah , Wonho Kim , R Jordan Barnett , Aditi Chandra , Jennifer M Luppino , Jailynn Harke , May Wai , Patrick J Walsh , Richard J Abdill , Rachel Yang , Yemin Lan , Sora Yoon , Rebecca Yunker , Masato T Kanemaki , Golnaz Vahedi , Jennifer E Phillips-Cremins , Rajan Jain , Eric F Joyce

Multi-feature clustering of CTCF binding creates robustness for loop extrusion blocking and Topologically Associating Domain boundaries.

Nature communications

Avec: Li-Hsin Chang , Sourav Ghosh , Andrea Papale , Jennifer M Luppino , Mélanie Miranda , Vincent Piras , Jéril Degrouard , Joanne Edouard , Mallory Poncelet , Nathan Lecouvreur , Sébastien Bloyer , Amélie Leforestier , Eric F Joyce , David Holcman , Daan Noordermeer

Single cell analysis pushes the boundaries of TAD formation and function.

Current opinion in genetics & development

Avec: Jennifer M Luppino , Eric F Joyce

BRD4 orchestrates genome folding to promote neural crest differentiation.

Nature genetics

Avec: Ricardo Linares-Saldana , Wonho Kim , Nikhita A Bolar , Haoyue Zhang , Bailey A Koch-Bojalad , Sora Yoon , Parisha P Shah , Ashley Karnay , Daniel S Park , Jennifer M Luppino , Son C Nguyen , Arun Padmanabhan , Cheryl L Smith , Andrey Poleshko , Qiaohong Wang , Li Li , Deepak Srivastava , Golnaz Vahedi , Gwang Hyeon Eom , Gerd A Blobel , Eric F Joyce , Rajan Jain

ARID1A spatially partitions interphase chromosomes.

Science advances

Avec: Shuai Wu , Nail Fatkhutdinov , Leah Rosin , Jennifer M Luppino , Osamu Iwasaki , Hideki Tanizawa , Hsin-Yao Tang , Andrew V Kossenkov , Alessandro Gardini , Ken-Ichi Noma , David W Speicher , Eric F Joyce , Rugang Zhang

CTCF blocks antisense transcription initiation at divergent promoters.

Nature structural & molecular biology

Avec: Jing Luan , Marit W Vermunt , Camille M Syrett , Allison Coté , Jacob M Tome , Haoyue Zhang , Anran Huang , Jennifer M Luppino , Cheryl A Keller , Belinda M Giardine , Shiping Zhang , Margaret C Dunagin , Zhe Zhang , Eric F Joyce , John T Lis , Arjun Raj , Ross C Hardison , Gerd A Blobel

Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression.

PLoS genetics

Avec: Jennifer M Luppino , Andrew Field , Son C Nguyen , Daniel S Park , Parisha P Shah , Richard J Abdill , Yemin Lan , Rebecca Yunker , Rajan Jain , Karen Adelman , Eric F Joyce

Réseau de co-auteurs

Eric F Joyce 9 collaborations

Son C Nguyen 5 collaborations

Daniel S Park 4 collaborations

Yemin Lan 3 collaborations

Rebecca Yunker 3 collaborations

Parisha P Shah 3 collaborations

Rajan Jain 3 collaborations

Jennifer E Phillips-Cremins 2 collaborations

Wonho Kim 2 collaborations

Richard J Abdill 2 collaborations

Sora Yoon 2 collaborations

Golnaz Vahedi 2 collaborations

Haoyue Zhang 2 collaborations

Gerd A Blobel 2 collaborations

Zhuxuan Xu 1 collaboration

Thomas Malachowski 1 collaboration

Keerthivasan Raanin Chandradoss 1 collaboration

Ravi Boya 1 collaboration

Linda Zhou 1 collaboration

Ashley L Cook 1 collaboration

Chuanbin Su 1 collaboration

Kenneth Pham 1 collaboration

Spencer A Haws 1 collaboration

Ji Hun Kim 1 collaboration

Han-Seul Ryu 1 collaboration

Chunmin Ge 1 collaboration

Katelyn R Titus 1 collaboration

Wanfeng Gong 1 collaboration

Owen Wallace 1 collaboration

Hao Wu 1 collaboration

Luis Alejandro Rojas 1 collaboration

Randi Isenhart 1 collaboration

R Jordan Barnett 1 collaboration

Aditi Chandra 1 collaboration

Jailynn Harke 1 collaboration

May Wai 1 collaboration

Patrick J Walsh 1 collaboration

Rachel Yang 1 collaboration

Masato T Kanemaki 1 collaboration

Li-Hsin Chang 1 collaboration

Sourav Ghosh 1 collaboration

Andrea Papale 1 collaboration

Mélanie Miranda 1 collaboration

Vincent Piras 1 collaboration

Jéril Degrouard 1 collaboration

Joanne Edouard 1 collaboration

Mallory Poncelet 1 collaboration

Nathan Lecouvreur 1 collaboration

Sébastien Bloyer 1 collaboration

Amélie Leforestier 1 collaboration

David Holcman 1 collaboration

Daan Noordermeer 1 collaboration

Ricardo Linares-Saldana 1 collaboration

Nikhita A Bolar 1 collaboration

Bailey A Koch-Bojalad 1 collaboration

Ashley Karnay 1 collaboration

Arun Padmanabhan 1 collaboration

Cheryl L Smith 1 collaboration

Andrey Poleshko 1 collaboration

Qiaohong Wang 1 collaboration

Li Li 1 collaboration

Deepak Srivastava 1 collaboration

Gwang Hyeon Eom 1 collaboration

Shuai Wu 1 collaboration

Nail Fatkhutdinov 1 collaboration

Leah Rosin 1 collaboration

Osamu Iwasaki 1 collaboration

Hideki Tanizawa 1 collaboration

Hsin-Yao Tang 1 collaboration

Andrew V Kossenkov 1 collaboration

Alessandro Gardini 1 collaboration

Ken-Ichi Noma 1 collaboration

David W Speicher 1 collaboration

Rugang Zhang 1 collaboration

Jing Luan 1 collaboration

Marit W Vermunt 1 collaboration

Camille M Syrett 1 collaboration

Allison Coté 1 collaboration

Jacob M Tome 1 collaboration

Anran Huang 1 collaboration

Cheryl A Keller 1 collaboration

Belinda M Giardine 1 collaboration

Shiping Zhang 1 collaboration

Margaret C Dunagin 1 collaboration

Zhe Zhang 1 collaboration

John T Lis 1 collaboration

Arjun Raj 1 collaboration

Ross C Hardison 1 collaboration

Andrew Field 1 collaboration

Karen Adelman 1 collaboration