James R Whittle

Affiliations

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.

Publications (7)

Targeting triple-negative breast cancers with the Smac-mimetic birinapant.

Cell death and differentiation

Avec: Najoua Lalaoui , Delphine Merino , Goknur Giner , François Vaillant , Diep Chau , Lin Liu , Tobias Kratina , Bhupinder Pal , James R Whittle , Nima Etemadi , Jean Berthelet , Julius Gräsel , Cathrine Hall , Matthew E Ritchie , Matthias Ernst , Gordon K Smyth , David L Vaux , Jane E Visvader , Geoffrey J Lindeman , John Silke

In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis.

Molecular oncology

Avec: Luuk Heitink , James R Whittle , François Vaillant , Bianca D Capaldo , Johanna F Dekkers , Caleb A Dawson , Michael J G Milevskiy , Elliot Surgenor , Minhsuang Tsai , Huei-Rong Chen , Michael Christie , Yunshun Chen , Gordon K Smyth , Marco J Herold , Andreas Strasser , Geoffrey J Lindeman , Jane E Visvader

How has the COVID-19 pandemic impacted clinical care and research in Neuro-Oncology?

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Avec: Angus Airth , James R Whittle , James Dimou

BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience.

Frontiers in oncology

Avec: Sarah M Trinder , Campbell McKay , Phoebe Power , Monique Topp , Bosco Chan , Santosh Valvi , Geoffrey McCowage , Dinisha Govender , Maria Kirby , David S Ziegler , Neevika Manoharan , Tim Hassall , Stewart Kellie , John Heath , Frank Alvaro , Paul Wood , Stephen Laughton , Karen Tsui , Andrew Dodgshun , David D Eisenstat , Raelene Endersby , Stephen J Luen , Eng-Siew Koh , Hao-Wen Sim , Benjamin Kong , Nicholas G Gottardo , James R Whittle , Dong-Anh Khuong-Quang , Jordan R Hansford

A risk-reward examination of sample multiplexing reagents for single cell RNA-Seq.

Genomics

Avec: Daniel V Brown , Casey J A Anttila , Ling Ling , Patrick Grave , Tracey M Baldwin , Ryan Munnings , Anthony J Farchione , Vanessa L Bryant , Amelia Dunstone , Christine Biben , Samir Taoudi , Tom S Weber , Shalin H Naik , Anthony Hadla , Holly E Barker , Cassandra J Vandenberg , Genevieve Dall , Clare L Scott , Zachery Moore , James R Whittle , Saskia Freytag , Sarah A Best , Anthony T Papenfuss , Sam W Z Olechnowicz , Sarah E MacRaild , Stephen Wilcox , Peter F Hickey , Daniela Amann-Zalcenstein , Rory Bowden

A brave new framework for glioma drug development.

The Lancet. Oncology

Avec: Kelly M Hotchkiss , Philipp Karschnia , Karisa C Schreck , Marjolein Geurts , Timothy F Cloughesy , Jason Huse , Elizabeth S Duke , Justin Lathia , David M Ashley , Edjah K Nduom , Georgina Long , Kirit Singh , Anthony Chalmers , Manmeet S Ahluwalia , Amy Heimberger , Stephen Bagley , Tomoki Todo , Roel Verhaak , Patrick D Kelly , Shawn Hervey-Jumper , John de Groot , Anoop Patel , Peter Fecci , Ian Parney , Victoria Wykes , Colin Watts , Terry C Burns , Nader Sanai , Matthias Preusser , Joerg Christian Tonn , Katharine J Drummond , Michael Platten , Sunit Das , Kirk Tanner , Michael A Vogelbaum , Michael Weller , James R Whittle , Mitchel S Berger , Mustafa Khasraw

Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: James R Whittle , François Vaillant , Elliot Surgenor , Antonia N Policheni , Göknur Giner , Bianca D Capaldo , Huei-Rong Chen , He K Liu , Johanna F Dekkers , Norman Sachs , Hans Clevers , Andrew Fellowes , Thomas Green , Huiling Xu , Stephen B Fox , Marco J Herold , Gordon K Smyth , Daniel H D Gray , Jane E Visvader , Geoffrey J Lindeman

Réseau de co-auteurs

François Vaillant 3 collaborations

Gordon K Smyth 3 collaborations

Jane E Visvader 3 collaborations

Geoffrey J Lindeman 3 collaborations

Bianca D Capaldo 2 collaborations

Johanna F Dekkers 2 collaborations

Elliot Surgenor 2 collaborations

Huei-Rong Chen 2 collaborations

Marco J Herold 2 collaborations

Najoua Lalaoui 1 collaboration

Delphine Merino 1 collaboration

Goknur Giner 1 collaboration

Diep Chau 1 collaboration

Lin Liu 1 collaboration

Tobias Kratina 1 collaboration

Bhupinder Pal 1 collaboration

Nima Etemadi 1 collaboration

Jean Berthelet 1 collaboration

Julius Gräsel 1 collaboration

Cathrine Hall 1 collaboration

Matthew E Ritchie 1 collaboration

Matthias Ernst 1 collaboration

David L Vaux 1 collaboration

John Silke 1 collaboration

Luuk Heitink 1 collaboration

Caleb A Dawson 1 collaboration

Michael J G Milevskiy 1 collaboration

Minhsuang Tsai 1 collaboration

Michael Christie 1 collaboration

Yunshun Chen 1 collaboration

Andreas Strasser 1 collaboration

Angus Airth 1 collaboration

James Dimou 1 collaboration

Sarah M Trinder 1 collaboration

Campbell McKay 1 collaboration

Phoebe Power 1 collaboration

Monique Topp 1 collaboration

Bosco Chan 1 collaboration

Santosh Valvi 1 collaboration

Geoffrey McCowage 1 collaboration

Dinisha Govender 1 collaboration

Maria Kirby 1 collaboration

David S Ziegler 1 collaboration

Neevika Manoharan 1 collaboration

Tim Hassall 1 collaboration

Stewart Kellie 1 collaboration

John Heath 1 collaboration

Frank Alvaro 1 collaboration

Paul Wood 1 collaboration

Stephen Laughton 1 collaboration

Karen Tsui 1 collaboration

Andrew Dodgshun 1 collaboration

David D Eisenstat 1 collaboration

Raelene Endersby 1 collaboration

Stephen J Luen 1 collaboration

Eng-Siew Koh 1 collaboration

Hao-Wen Sim 1 collaboration

Benjamin Kong 1 collaboration

Nicholas G Gottardo 1 collaboration

Dong-Anh Khuong-Quang 1 collaboration

Jordan R Hansford 1 collaboration

Daniel V Brown 1 collaboration

Casey J A Anttila 1 collaboration

Ling Ling 1 collaboration

Patrick Grave 1 collaboration

Tracey M Baldwin 1 collaboration

Ryan Munnings 1 collaboration

Anthony J Farchione 1 collaboration

Vanessa L Bryant 1 collaboration

Amelia Dunstone 1 collaboration

Christine Biben 1 collaboration

Samir Taoudi 1 collaboration

Tom S Weber 1 collaboration

Shalin H Naik 1 collaboration

Anthony Hadla 1 collaboration

Holly E Barker 1 collaboration

Cassandra J Vandenberg 1 collaboration

Genevieve Dall 1 collaboration

Clare L Scott 1 collaboration

Zachery Moore 1 collaboration

Saskia Freytag 1 collaboration

Sarah A Best 1 collaboration

Anthony T Papenfuss 1 collaboration

Sam W Z Olechnowicz 1 collaboration

Sarah E MacRaild 1 collaboration

Stephen Wilcox 1 collaboration

Peter F Hickey 1 collaboration

Daniela Amann-Zalcenstein 1 collaboration

Rory Bowden 1 collaboration

Kelly M Hotchkiss 1 collaboration

Philipp Karschnia 1 collaboration

Karisa C Schreck 1 collaboration

Marjolein Geurts 1 collaboration

Timothy F Cloughesy 1 collaboration

Jason Huse 1 collaboration

Elizabeth S Duke 1 collaboration

Justin Lathia 1 collaboration

David M Ashley 1 collaboration

Edjah K Nduom 1 collaboration

Georgina Long 1 collaboration

Kirit Singh 1 collaboration

Anthony Chalmers 1 collaboration

Manmeet S Ahluwalia 1 collaboration

Amy Heimberger 1 collaboration

Stephen Bagley 1 collaboration

Tomoki Todo 1 collaboration

Roel Verhaak 1 collaboration

Patrick D Kelly 1 collaboration

Shawn Hervey-Jumper 1 collaboration

John de Groot 1 collaboration

Anoop Patel 1 collaboration

Peter Fecci 1 collaboration

Ian Parney 1 collaboration

Victoria Wykes 1 collaboration

Colin Watts 1 collaboration

Terry C Burns 1 collaboration

Nader Sanai 1 collaboration

Matthias Preusser 1 collaboration

Joerg Christian Tonn 1 collaboration

Katharine J Drummond 1 collaboration

Michael Platten 1 collaboration

Sunit Das 1 collaboration

Kirk Tanner 1 collaboration

Michael A Vogelbaum 1 collaboration

Michael Weller 1 collaboration

Mitchel S Berger 1 collaboration

Mustafa Khasraw 1 collaboration

Antonia N Policheni 1 collaboration

Göknur Giner 1 collaboration

He K Liu 1 collaboration

Norman Sachs 1 collaboration

Hans Clevers 1 collaboration

Andrew Fellowes 1 collaboration

Thomas Green 1 collaboration

Huiling Xu 1 collaboration

Stephen B Fox 1 collaboration

Daniel H D Gray 1 collaboration