Jakub Orlowski

Publications (9)

Sleep and daytime behavior in individuals with Christianson Syndrome.

Sleep medicine

Avec: Reut Gruber , Samantha Scholes , Armando Bertone , R Anne McKinney , John Orlowski , Merrill S Wise

Roles of Endomembrane Alkali Cation/Proton Exchangers in Synaptic Function and Neurodevelopmental Disorders.

Frontiers in physiology

Avec: Andy Y L Gao , Etienne Lourdin-De Filippis , John Orlowski , R Anne McKinney

Structure and mechanism of the human NHE1-CHP1 complex.

Nature communications

Avec: Yanli Dong , Yiwei Gao , Alina Ilie , DuSik Kim , Annie Boucher , Bin Li , Xuejun C Zhang , John Orlowski , Yan Zhao

Nuclear SMAD5 dances to a different tune in regulating insulin secretion.

Cell metabolism

Avec: John Orlowski

Impaired hippocampal plasticity associated with loss of recycling endosomal SLC9A6/NHE6 is ameliorated by the TrkB agonist 7,8-dihydroxyflavone.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Andy Y L Gao , Yanis Inglebert , Roy Shi , Alina Ilie , Jelena Popic , Jamie Mustian , Nahum Sonenberg , John Orlowski , R Anne McKinney

Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX.

Scientific reports

Avec: Abira Rajah , Colton G Boudreau , Alina Ilie , Tse-Luen Wee , Kaixi Tang , Aleksandar Z Borisov , John Orlowski , Claire M Brown

A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome.

Neurobiology of disease

Avec: Alina Ilie , Andy Y L Gao , Annie Boucher , Jaeok Park , Albert M Berghuis , Mariëtte J V Hoffer , Yvonne Hilhorst-Hofstee , R Anne McKinney , John Orlowski

Loss of SLC9A6/NHE6 impairs nociception in a mouse model of Christianson syndrome.

Pain

Avec: Hugues Petitjean , Tarheen Fatima , Stephanie Mouchbahani-Constance , Albena Davidova , Catherine E Ferland , John Orlowski , Reza Sharif-Naeini

Structural basis of autoinhibition of the human NHE3-CHP1 complex.

Science advances

Avec: Yanli Dong , Hang Li , Alina Ilie , Yiwei Gao , Annie Boucher , Xuejun Cai Zhang , John Orlowski , Yan Zhao

Réseau de co-auteurs

John Orlowski 9 collaborations

Alina Ilie 5 collaborations

R Anne McKinney 4 collaborations

Andy Y L Gao 3 collaborations

Annie Boucher 3 collaborations

Yanli Dong 2 collaborations

Yiwei Gao 2 collaborations

Yan Zhao 2 collaborations

Reut Gruber 1 collaboration

Samantha Scholes 1 collaboration

Armando Bertone 1 collaboration

Merrill S Wise 1 collaboration

Etienne Lourdin-De Filippis 1 collaboration

DuSik Kim 1 collaboration

Bin Li 1 collaboration

Xuejun C Zhang 1 collaboration

Yanis Inglebert 1 collaboration

Roy Shi 1 collaboration

Jelena Popic 1 collaboration

Jamie Mustian 1 collaboration

Nahum Sonenberg 1 collaboration

Abira Rajah 1 collaboration

Colton G Boudreau 1 collaboration

Tse-Luen Wee 1 collaboration

Kaixi Tang 1 collaboration

Aleksandar Z Borisov 1 collaboration

Claire M Brown 1 collaboration

Jaeok Park 1 collaboration

Albert M Berghuis 1 collaboration

Mariëtte J V Hoffer 1 collaboration

Yvonne Hilhorst-Hofstee 1 collaboration

Hugues Petitjean 1 collaboration

Tarheen Fatima 1 collaboration

Stephanie Mouchbahani-Constance 1 collaboration

Albena Davidova 1 collaboration

Catherine E Ferland 1 collaboration

Reza Sharif-Naeini 1 collaboration

Hang Li 1 collaboration

Xuejun Cai Zhang 1 collaboration