Jacques Behmoaras

Affiliations

Centre for Inflammatory Disease, Imperial College London, London W12 0NN, UK. Electronic address: jacques.behmoaras@imperial.ac.uk.

Publications (21)

Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo.

Cell reports

Avec: Marie Pereira , Tai-Di Chen , Norzawani Buang , Antoni Olona , Jeong-Hun Ko , Maria Prendecki , Ana S H Costa , Efterpi Nikitopoulou , Laura Tronci , Charles D Pusey , H Terence Cook , Stephen P McAdoo , Christian Frezza , Jacques Behmoaras

BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages.

Journal of cell science

Avec: Jeong-Hun Ko , Antoni Olona , Adonia E Papathanassiu , Norzawani Buang , Kwon-Sik Park , Ana S H Costa , Claudio Mauro , Christian Frezza , Jacques Behmoaras

Adipoclast: a multinucleated fat-eating macrophage.

BMC biology

Avec: Antoni Olona , Subhankar Mukhopadhyay , Charlotte Hateley , Fernando O Martinez , Siamon Gordon , Jacques Behmoaras

Immunolipidomics Reveals a Globoside Network During the Resolution of Pro-Inflammatory Response in Human Macrophages.

Frontiers in immunology

Avec: Sneha Muralidharan , Federico Torta , Michelle K Lin , Antoni Olona , Marta Bagnati , Aida Moreno-Moral , Jeong-Hun Ko , Shanshan Ji , Bo Burla , Markus R Wenk , Hosana G Rodrigues , Enrico Petretto , Jacques Behmoaras

Cardiac glycosides are broad-spectrum senolytics.

Nature metabolism

Avec: Ana Guerrero , Nicolás Herranz , Bin Sun , Verena Wagner , Suchira Gallage , Romain Guiho , Katharina Wolter , Joaquim Pombo , Elaine E Irvine , Andrew J Innes , Jodie Birch , Justyna Glegola , Saba Manshaei , Danijela Heide , Gopuraja Dharmalingam , Jule Harbig , Antoni Olona , Jacques Behmoaras , Daniel Dauch , Anthony G Uren , Lars Zender , Santiago Vernia , Juan Pedro Martínez-Barbera , Mathias Heikenwalder , Dominic J Withers , Jesús Gil

Sphingolipid metabolism during Toll-like receptor 4 (TLR4)-mediated macrophage activation.

British journal of pharmacology

Avec: Antoni Olona , Charlotte Hateley , Sneha Muralidharan , Markus R Wenk , Federico Torta , Jacques Behmoaras

Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways.

The Journal of pathology

Avec: Maria Prendecki , Stephen P McAdoo , Tabitha Turner-Stokes , Ana Garcia-Diaz , Isabel Orriss , Kevin J Woollard , Jacques Behmoaras , H Terence Cook , Robert Unwin , Charles D Pusey , Timothy J Aitman , Frederick Wk Tam

The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis.

Nature communications

Avec: Huimei Chen , Gabriel Chew , Nithya Devapragash , Jui Zhi Loh , Kevin Y Huang , Jing Guo , Shiyang Liu , Elisabeth Li Sa Tan , Shuang Chen , Nicole Gui Zhen Tee , Masum M Mia , Manvendra K Singh , Aihua Zhang , Jacques Behmoaras , Enrico Petretto

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing.

JCI insight

Avec: Marta Bagnati , Aida Moreno-Moral , Jeong-Hun Ko , Jérôme Nicod , Nathan Harmston , Martha Imprialou , Laurence Game , Jesus Gil , Enrico Petretto , Jacques Behmoaras

Similarities and interplay between senescent cells and macrophages.

The Journal of cell biology

Avec: Jacques Behmoaras , Jesús Gil

Comparative Analysis of Single-Cell RNA Sequencing Methods with and without Sample Multiplexing.

International journal of molecular sciences

Avec: Yi Xie , Huimei Chen , Vasuki Ranjani Chellamuthu , Ahmad Bin Mohamed Lajam , Salvatore Albani , Andrea Hsiu Ling Low , Enrico Petretto , Jacques Behmoaras

Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity.

EBioMedicine

Avec: Charlotte Hateley , Antoni Olona , Laura Halliday , Matthew L Edin , Jeong-Hun Ko , Roberta Forlano , Ximena Terra , Fred B Lih , Raúl Beltrán-Debón , Penelopi Manousou , Sanjay Purkayastha , Krishna Moorthy , Mark R Thursz , Guodong Zhang , Robert D Goldin , Darryl C Zeldin , Enrico Petretto , Jacques Behmoaras

A trans-eQTL network regulates osteoclast multinucleation and bone mass.

eLife

Avec: Marie Pereira , Jeong-Hun Ko , John Logan , Hayley Protheroe , Kee-Beom Kim , Amelia Li Min Tan , Peter I Croucher , Kwon-Sik Park , Maxime Rotival , Enrico Petretto , Jh Duncan Bassett , Graham R Williams , Jacques Behmoaras

Cardiac glycosides cause cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis.

British journal of pharmacology

Avec: Antoni Olona , Charlotte Hateley , Ana Guerrero , Jeong-Hun Ko , Michael R Johnson , Paras K Anand , David Thomas , Jesus Gil , Jacques Behmoaras

Multinucleation resets human macrophages for specialized functions at the expense of their identity.

EMBO reports

Avec: Kourosh Ahmadzadeh , Marie Pereira , Margot Vanoppen , Eline Bernaerts , Jeong-Hun Ko , Tania Mitera , Christy Maksoudian , Bella B Manshian , Stefaan Soenen , Carlos D Rose , Patrick Matthys , Carine Wouters , Jacques Behmoaras

WWP2 Regulates Kidney Fibrosis and the Metabolic Reprogramming of Profibrotic Myofibroblasts.

Journal of the American Society of Nephrology : JASN

Avec: Huimei Chen , Ran You , Jing Guo , Wei Zhou , Gabriel Chew , Nithya Devapragash , Jui Zhi Loh , Loreto Gesualdo , Yanwei Li , Yuteng Jiang , Elisabeth Li Sa Tan , Shuang Chen , Paola Pontrelli , Francesco Pesce , Jacques Behmoaras , Aihua Zhang , Enrico Petretto

The versatile biochemistry of iron in macrophage effector functions.

The FEBS journal

Avec: Jacques Behmoaras

Type I interferons affect the metabolic fitness of CD8

Nature communications

Avec: Norzawani Buang , Lunnathaya Tapeng , Victor Gray , Alessandro Sardini , Chad Whilding , Liz Lightstone , Thomas D Cairns , Matthew C Pickering , Jacques Behmoaras , Guang Sheng Ling , Marina Botto

Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death.

eLife

Avec: Jack Gisby , Candice L Clarke , Nicholas Medjeral-Thomas , Talat H Malik , Artemis Papadaki , Paige M Mortimer , Norzawani B Buang , Shanice Lewis , Marie Pereira , Frederic Toulza , Ester Fagnano , Marie-Anne Mawhin , Emma E Dutton , Lunnathaya Tapeng , Arianne C Richard , Paul Dw Kirk , Jacques Behmoaras , Eleanor Sandhu , Stephen P McAdoo , Maria F Prendecki , Matthew C Pickering , Marina Botto , Michelle Willicombe , David C Thomas , James E Peters

Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis.

eLife

Avec: John F Ouyang , Kunal Mishra , Yi Xie , Harry Park , Kevin Y Huang , Enrico Petretto , Jacques Behmoaras

Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation.

Cell reports

Avec: Stuart Leishman , Najd M Aljadeed , Liyunhe Qian , Shamshad Cockcroft , Jacques Behmoaras , Paras K Anand

Réseau de co-auteurs

Antoni Olona 8 collaborations

Jeong-Hun Ko 8 collaborations

Enrico Petretto 8 collaborations

Marie Pereira 4 collaborations

Charlotte Hateley 4 collaborations

Norzawani Buang 3 collaborations

Stephen P McAdoo 3 collaborations

Huimei Chen 3 collaborations

Maria Prendecki 2 collaborations

Ana S H Costa 2 collaborations

Charles D Pusey 2 collaborations

H Terence Cook 2 collaborations

Christian Frezza 2 collaborations

Kwon-Sik Park 2 collaborations

Sneha Muralidharan 2 collaborations

Federico Torta 2 collaborations

Marta Bagnati 2 collaborations

Aida Moreno-Moral 2 collaborations

Markus R Wenk 2 collaborations

Ana Guerrero 2 collaborations

Jesús Gil 2 collaborations

Gabriel Chew 2 collaborations

Nithya Devapragash 2 collaborations

Jui Zhi Loh 2 collaborations

Kevin Y Huang 2 collaborations

Jing Guo 2 collaborations

Elisabeth Li Sa Tan 2 collaborations

Shuang Chen 2 collaborations

Aihua Zhang 2 collaborations

Jesus Gil 2 collaborations

Yi Xie 2 collaborations

Paras K Anand 2 collaborations

Lunnathaya Tapeng 2 collaborations

Matthew C Pickering 2 collaborations

Marina Botto 2 collaborations

Tai-Di Chen 1 collaboration

Efterpi Nikitopoulou 1 collaboration

Laura Tronci 1 collaboration

Adonia E Papathanassiu 1 collaboration

Claudio Mauro 1 collaboration

Subhankar Mukhopadhyay 1 collaboration

Fernando O Martinez 1 collaboration

Siamon Gordon 1 collaboration

Michelle K Lin 1 collaboration

Shanshan Ji 1 collaboration

Bo Burla 1 collaboration

Hosana G Rodrigues 1 collaboration

Nicolás Herranz 1 collaboration

Bin Sun 1 collaboration

Verena Wagner 1 collaboration

Suchira Gallage 1 collaboration

Romain Guiho 1 collaboration

Katharina Wolter 1 collaboration

Joaquim Pombo 1 collaboration

Elaine E Irvine 1 collaboration

Andrew J Innes 1 collaboration

Jodie Birch 1 collaboration

Justyna Glegola 1 collaboration

Saba Manshaei 1 collaboration

Danijela Heide 1 collaboration

Gopuraja Dharmalingam 1 collaboration

Jule Harbig 1 collaboration

Daniel Dauch 1 collaboration

Anthony G Uren 1 collaboration

Lars Zender 1 collaboration

Santiago Vernia 1 collaboration

Juan Pedro Martínez-Barbera 1 collaboration

Mathias Heikenwalder 1 collaboration

Dominic J Withers 1 collaboration

Tabitha Turner-Stokes 1 collaboration

Ana Garcia-Diaz 1 collaboration

Isabel Orriss 1 collaboration

Kevin J Woollard 1 collaboration

Robert Unwin 1 collaboration

Timothy J Aitman 1 collaboration

Frederick Wk Tam 1 collaboration

Shiyang Liu 1 collaboration

Nicole Gui Zhen Tee 1 collaboration

Masum M Mia 1 collaboration

Manvendra K Singh 1 collaboration

Jérôme Nicod 1 collaboration

Nathan Harmston 1 collaboration

Martha Imprialou 1 collaboration

Laurence Game 1 collaboration

Vasuki Ranjani Chellamuthu 1 collaboration

Ahmad Bin Mohamed Lajam 1 collaboration

Salvatore Albani 1 collaboration

Andrea Hsiu Ling Low 1 collaboration

Laura Halliday 1 collaboration

Matthew L Edin 1 collaboration

Roberta Forlano 1 collaboration

Ximena Terra 1 collaboration

Fred B Lih 1 collaboration

Raúl Beltrán-Debón 1 collaboration

Penelopi Manousou 1 collaboration

Sanjay Purkayastha 1 collaboration

Krishna Moorthy 1 collaboration

Mark R Thursz 1 collaboration

Guodong Zhang 1 collaboration

Robert D Goldin 1 collaboration

Darryl C Zeldin 1 collaboration

John Logan 1 collaboration

Hayley Protheroe 1 collaboration

Kee-Beom Kim 1 collaboration

Amelia Li Min Tan 1 collaboration

Peter I Croucher 1 collaboration

Maxime Rotival 1 collaboration

Jh Duncan Bassett 1 collaboration

Graham R Williams 1 collaboration

Michael R Johnson 1 collaboration

David Thomas 1 collaboration

Kourosh Ahmadzadeh 1 collaboration

Margot Vanoppen 1 collaboration

Eline Bernaerts 1 collaboration

Tania Mitera 1 collaboration

Christy Maksoudian 1 collaboration

Bella B Manshian 1 collaboration

Stefaan Soenen 1 collaboration

Carlos D Rose 1 collaboration

Patrick Matthys 1 collaboration

Carine Wouters 1 collaboration

Ran You 1 collaboration

Wei Zhou 1 collaboration

Loreto Gesualdo 1 collaboration

Yanwei Li 1 collaboration

Yuteng Jiang 1 collaboration

Paola Pontrelli 1 collaboration

Francesco Pesce 1 collaboration

Victor Gray 1 collaboration

Alessandro Sardini 1 collaboration

Chad Whilding 1 collaboration

Liz Lightstone 1 collaboration

Thomas D Cairns 1 collaboration

Guang Sheng Ling 1 collaboration

Jack Gisby 1 collaboration

Candice L Clarke 1 collaboration

Nicholas Medjeral-Thomas 1 collaboration

Talat H Malik 1 collaboration

Artemis Papadaki 1 collaboration

Paige M Mortimer 1 collaboration

Norzawani B Buang 1 collaboration

Shanice Lewis 1 collaboration

Frederic Toulza 1 collaboration

Ester Fagnano 1 collaboration

Marie-Anne Mawhin 1 collaboration

Emma E Dutton 1 collaboration

Arianne C Richard 1 collaboration

Paul Dw Kirk 1 collaboration

Eleanor Sandhu 1 collaboration

Maria F Prendecki 1 collaboration

Michelle Willicombe 1 collaboration

David C Thomas 1 collaboration

James E Peters 1 collaboration

John F Ouyang 1 collaboration

Kunal Mishra 1 collaboration

Harry Park 1 collaboration

Stuart Leishman 1 collaboration

Najd M Aljadeed 1 collaboration

Liyunhe Qian 1 collaboration

Shamshad Cockcroft 1 collaboration