Jérôme Basquin

Affiliations

Department of Structural Cell Biology, MPI of Biochemistry, Munich, Germany.

Publications (32)

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

Nucleic acids research

Avec: Virginia Busetto , Isabelle Barbosa , Jérôme Basquin , Émelie Marquenet , Rémi Hocq , Magali Hennion , Janio Antonio Paternina , Abdelkader Namane , Elena Conti , Olivier Bensaude , Hervé Le Hir

To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome.

Cold Spring Harbor symposia on quantitative biology

Avec: Mahesh Lingaraju , Jan M Schuller , Sebastian Falk , Piotr Gerlach , Fabien Bonneau , Jérôme Basquin , Christian Benda , Elena Conti

Targeted In Situ Protein Diversification and Intra-organelle Validation in Mammalian Cells.

Cell chemical biology

Avec: Mutlu Erdogan , Arne Fabritius , Jérome Basquin , Oliver Griesbeck

Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.

eLife

Avec: Sandra K Schuller , Jan M Schuller , J Rajan Prabu , Marc Baumgärtner , Fabien Bonneau , Jérôme Basquin , Elena Conti

CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.

Nature chemical biology

Avec: Sebastian Kostrhon , J Rajan Prabu , Kheewoong Baek , Daniel Horn-Ghetko , Susanne von Gronau , Maren Klügel , Jérôme Basquin , Arno F Alpi , Brenda A Schulman

Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.

Nature structural & molecular biology

Avec: Wataru Kobayashi , Anna H Sappler , Daniel Bollschweiler , Maximilian Kümmecke , Jérôme Basquin , Eda Nur Arslantas , Siwat Ruangroengkulrith , Renate Hornberger , Karl Duderstadt , Kikuë Tachibana

Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions.

Genes & development

Avec: Fabien Bonneau , Jérôme Basquin , Barbara Steigenberger , Tillman Schäfer , Ingmar B Schäfer , Elena Conti

Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function.

Virus research

Avec: Irene Boniardi , Angela Corona , Jerome Basquin , Claire Basquin , Jessica Milia , István Nagy , Enzo Tramontano , Luca Zinzula

Fluorescent sensors for imaging of interstitial calcium.

Nature communications

Avec: Ariel A Valiente-Gabioud , Inés Garteizgogeascoa Suñer , Agata Idziak , Arne Fabritius , Jérome Basquin , Julie Angibaud , U Valentin Nägerl , Sumeet Pal Singh , Oliver Griesbeck

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.

Nature communications

Avec: Mahesh Lingaraju , Dennis Johnsen , Andreas Schlundt , Lukas M Langer , Jérôme Basquin , Michael Sattler , Torben Heick Jensen , Sebastian Falk , Elena Conti

Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.

Nature communications

Avec: Sabine Bachmaier , Yuri Volpato Santos , Susanne Kramer , George Boniface Githure , Thomas Klöckner , Julia Pepperl , Cordula Baums , Robin Schenk , Frank Schwede , Hans-Gottfried Genieser , Jean-William Dupuy , Ignasi Forné , Axel Imhof , Jerôme Basquin , Esben Lorentzen , Michael Boshart

Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly.

The EMBO journal

Avec: Stefanie Wachter , Jamin Jung , Shahaan Shafiq , Jerome Basquin , Cécile Fort , Philippe Bastin , Esben Lorentzen

Long-wavelength native-SAD phasing: opportunities and challenges.

IUCrJ

Avec: Shibom Basu , Vincent Olieric , Filip Leonarski , Naohiro Matsugaki , Yoshiaki Kawano , Tomizaki Takashi , Chia-Ying Huang , Yusuke Yamada , Laura Vera , Natacha Olieric , Jerome Basquin , Justyna A Wojdyla , Oliver Bunk , Kay Diederichs , Masaki Yamamoto , Meitian Wang

Evolution of a histone variant involved in compartmental regulation of NAD metabolism.

Nature structural & molecular biology

Avec: Iva Guberovic , Sarah Hurtado-Bagès , Ciro Rivera-Casas , Gunnar Knobloch , Roberto Malinverni , Vanesa Valero , Michelle M Leger , Jesús García , Jerome Basquin , Marta Gómez de Cedrón , Marta Frigolé-Vivas , Manjinder S Cheema , Ainhoa Pérez , Juan Ausió , Ana Ramírez de Molina , Xavier Salvatella , Iñaki Ruiz-Trillo , Jose M Eirin-Lopez , Andreas G Ladurner , Marcus Buschbeck

Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism.

Pharmaceuticals (Basel, Switzerland)

Avec: Dorota Kubacka , Mateusz Kozarski , Marek R Baranowski , Radoslaw Wojcik , Joanna Panecka-Hofman , Dominika Strzelecka , Jerome Basquin , Jacek Jemielity , Joanna Kowalska

High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.

Biochemical and biophysical research communications

Avec: Luca Zinzula , Jerome Basquin , Stefan Bohn , Florian Beck , Sven Klumpe , Günter Pfeifer , István Nagy , Andreas Bracher , F Ulrich Hartl , Wolfgang Baumeister

Self-organization of

Science (New York, N.Y.)

Avec: Young-Min Soh , Iain Finley Davidson , Stefano Zamuner , Jérôme Basquin , Florian Patrick Bock , Michael Taschner , Jan-Willem Veening , Paolo De Los Rios , Jan-Michael Peters , Stephan Gruber

Structural basis of PETISCO complex assembly during piRNA biogenesis in

Genes & development

Avec: Cecilia Perez-Borrajero , Nadezda Podvalnaya , Kay Holleis , Raffael Lichtenberger , Emil Karaulanov , Bernd Simon , Jérôme Basquin , Janosch Hennig , René F Ketting , Sebastian Falk

UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.

Nucleic acids research

Avec: Lukas M Langer , Katharina Kurscheidt , Jérôme Basquin , Fabien Bonneau , Iuliia Iermak , Claire Basquin , Elena Conti

Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism.

Angewandte Chemie (International ed. in English)

Avec: Chloe Langley , Evangelos Tatsis , Benke Hong , Yoko Nakamura , Christian Paetz , Clare E M Stevenson , Jerome Basquin , David M Lawson , Lorenzo Caputi , Sarah E O'Connor

Directed Evolution of Piperazic Acid Incorporation by a Nonribosomal Peptide Synthetase.

Angewandte Chemie (International ed. in English)

Avec: Philipp Stephan , Chloe Langley , Daniela Winkler , Jérôme Basquin , Lorenzo Caputi , Sarah E O'Connor , Hajo Kries

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens.

eLife

Avec: Veronica Teresa Ober , George Boniface Githure , Yuri Volpato Santos , Sidney Becker , Gabriel Moya Munoz , Jérôme Basquin , Frank Schwede , Esben Lorentzen , Michael Boshart

Purification and crystal structure of human ODA16: Implications for ciliary import of outer dynein arms by the intraflagellar transport machinery.

Protein science : a publication of the Protein Society

Avec: Jiaolong Wang , Michael Taschner , Narcis A Petriman , Marie B Andersen , Jerome Basquin , Sagar Bhogaraju , Melanie Vetter , Stefanie Wachter , Anna Lorentzen , Esben Lorentzen

A rod conformation of the Pyrococcus furiosus Rad50 coiled coil.

Proteins

Avec: Young-Min Soh , Jerome Basquin , Stephan Gruber

Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.

Journal of molecular biology

Avec: Jakub Chrustowicz , Dawafuti Sherpa , Joan Teyra , Mun Siong Loke , Grzegorz M Popowicz , Jerome Basquin , Michael Sattler , J Rajan Prabu , Sachdev S Sidhu , Brenda A Schulman

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.

The EMBO journal

Avec: Michael Taschner , Jérôme Basquin , Barbara Steigenberger , Ingmar B Schäfer , Young-Min Soh , Claire Basquin , Esben Lorentzen , Markus Räschle , Richard A Scheltema , Stephan Gruber

A structural biology community assessment of AlphaFold2 applications.

Nature structural & molecular biology

Avec: Mehmet Akdel , Douglas E V Pires , Eduard Porta Pardo , Jürgen Jänes , Arthur O Zalevsky , Bálint Mészáros , Patrick Bryant , Lydia L Good , Roman A Laskowski , Gabriele Pozzati , Aditi Shenoy , Wensi Zhu , Petras Kundrotas , Victoria Ruiz Serra , Carlos H M Rodrigues , Alistair S Dunham , David Burke , Neera Borkakoti , Sameer Velankar , Adam Frost , Jérôme Basquin , Kresten Lindorff-Larsen , Alex Bateman , Andrey V Kajava , Alfonso Valencia , Sergey Ovchinnikov , Janani Durairaj , David B Ascher , Janet M Thornton , Norman E Davey , Amelie Stein , Arne Elofsson , Tristan I Croll , Pedro Beltrao

Biocatalytic routes to stereo-divergent iridoids.

Nature communications

Avec: Néstor J Hernández Lozada , Benke Hong , Joshua C Wood , Lorenzo Caputi , Jérôme Basquin , Ling Chuang , Maritta Kunert , Carlos E Rodríguez López , Chloe Langley , Dongyan Zhao , C Robin Buell , Benjamin R Lichman , Sarah E O'Connor

The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.

Cell reports

Avec: Fabienne Mauxion , Jérôme Basquin , Sevim Ozgur , Marion Rame , Jana Albrecht , Ingmar Schäfer , Bertrand Séraphin , Elena Conti

Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.

Molecular cell

Avec: Piotr Gerlach , William Garland , Mahesh Lingaraju , Anna Salerno-Kochan , Fabien Bonneau , Jérôme Basquin , Torben Heick Jensen , Elena Conti

A SAM-key domain required for enzymatic activity of the Fun30 nucleosome remodeler.

Life science alliance

Avec: Leonhard A Karl , Lorenzo Galanti , Susanne Cs Bantele , Felix Metzner , Barbara Šafarić , Lional Rajappa , Benjamin Foster , Vanessa Borges Pires , Priyanka Bansal , Erika Chacin , Jerôme Basquin , Karl E Duderstadt , Christoph F Kurat , Till Bartke , Karl-Peter Hopfner , Boris Pfander

Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells.

Science signaling

Avec: Lukas Spiller , Ramu Manjula , Franz Leissing , Jerome Basquin , Priscila Bourilhon , Dzmitry Sinitski , Markus Brandhofer , Sophie Levecque , Simona Gerra , Björn Sabelleck , Lin Zhang , Regina Feederle , Andrew Flatley , Adrian Hoffmann , Ralph Panstruga , Jürgen Bernhagen , Elias Lolis

Réseau de co-auteurs

Jerome Basquin 11 collaborations

Elena Conti 8 collaborations

Fabien Bonneau 5 collaborations

Esben Lorentzen 5 collaborations

Mahesh Lingaraju 3 collaborations

Sebastian Falk 3 collaborations

J Rajan Prabu 3 collaborations

Claire Basquin 3 collaborations

Young-Min Soh 3 collaborations

Michael Taschner 3 collaborations

Stephan Gruber 3 collaborations

Chloe Langley 3 collaborations

Lorenzo Caputi 3 collaborations

Sarah E O'Connor 3 collaborations

Jan M Schuller 2 collaborations

Piotr Gerlach 2 collaborations

Arne Fabritius 2 collaborations

Jérome Basquin 2 collaborations

Oliver Griesbeck 2 collaborations

Brenda A Schulman 2 collaborations

Barbara Steigenberger 2 collaborations

Ingmar B Schäfer 2 collaborations

István Nagy 2 collaborations

Luca Zinzula 2 collaborations

Lukas M Langer 2 collaborations

Michael Sattler 2 collaborations

Torben Heick Jensen 2 collaborations

Yuri Volpato Santos 2 collaborations

George Boniface Githure 2 collaborations

Frank Schwede 2 collaborations

Jerôme Basquin 2 collaborations

Michael Boshart 2 collaborations

Stefanie Wachter 2 collaborations

Benke Hong 2 collaborations

Virginia Busetto 1 collaboration

Isabelle Barbosa 1 collaboration

Émelie Marquenet 1 collaboration

Rémi Hocq 1 collaboration

Magali Hennion 1 collaboration

Janio Antonio Paternina 1 collaboration

Abdelkader Namane 1 collaboration

Olivier Bensaude 1 collaboration

Hervé Le Hir 1 collaboration

Christian Benda 1 collaboration

Mutlu Erdogan 1 collaboration

Sandra K Schuller 1 collaboration

Marc Baumgärtner 1 collaboration

Sebastian Kostrhon 1 collaboration

Kheewoong Baek 1 collaboration

Daniel Horn-Ghetko 1 collaboration

Susanne von Gronau 1 collaboration

Maren Klügel 1 collaboration

Arno F Alpi 1 collaboration

Wataru Kobayashi 1 collaboration

Anna H Sappler 1 collaboration

Daniel Bollschweiler 1 collaboration

Maximilian Kümmecke 1 collaboration

Eda Nur Arslantas 1 collaboration

Siwat Ruangroengkulrith 1 collaboration

Renate Hornberger 1 collaboration

Karl Duderstadt 1 collaboration

Kikuë Tachibana 1 collaboration

Tillman Schäfer 1 collaboration

Irene Boniardi 1 collaboration

Angela Corona 1 collaboration

Jessica Milia 1 collaboration

Enzo Tramontano 1 collaboration

Ariel A Valiente-Gabioud 1 collaboration

Inés Garteizgogeascoa Suñer 1 collaboration

Agata Idziak 1 collaboration

Julie Angibaud 1 collaboration

U Valentin Nägerl 1 collaboration

Sumeet Pal Singh 1 collaboration

Dennis Johnsen 1 collaboration

Andreas Schlundt 1 collaboration

Sabine Bachmaier 1 collaboration

Susanne Kramer 1 collaboration

Thomas Klöckner 1 collaboration

Julia Pepperl 1 collaboration

Cordula Baums 1 collaboration

Robin Schenk 1 collaboration

Hans-Gottfried Genieser 1 collaboration

Jean-William Dupuy 1 collaboration

Ignasi Forné 1 collaboration

Axel Imhof 1 collaboration

Jamin Jung 1 collaboration

Shahaan Shafiq 1 collaboration

Cécile Fort 1 collaboration

Philippe Bastin 1 collaboration

Shibom Basu 1 collaboration

Vincent Olieric 1 collaboration

Filip Leonarski 1 collaboration

Naohiro Matsugaki 1 collaboration

Yoshiaki Kawano 1 collaboration

Tomizaki Takashi 1 collaboration

Chia-Ying Huang 1 collaboration

Yusuke Yamada 1 collaboration

Laura Vera 1 collaboration

Natacha Olieric 1 collaboration

Justyna A Wojdyla 1 collaboration

Oliver Bunk 1 collaboration

Kay Diederichs 1 collaboration

Masaki Yamamoto 1 collaboration

Meitian Wang 1 collaboration

Iva Guberovic 1 collaboration

Sarah Hurtado-Bagès 1 collaboration

Ciro Rivera-Casas 1 collaboration

Gunnar Knobloch 1 collaboration

Roberto Malinverni 1 collaboration

Vanesa Valero 1 collaboration

Michelle M Leger 1 collaboration

Jesús García 1 collaboration

Marta Gómez de Cedrón 1 collaboration

Marta Frigolé-Vivas 1 collaboration

Manjinder S Cheema 1 collaboration

Ainhoa Pérez 1 collaboration

Juan Ausió 1 collaboration

Ana Ramírez de Molina 1 collaboration

Xavier Salvatella 1 collaboration

Iñaki Ruiz-Trillo 1 collaboration

Jose M Eirin-Lopez 1 collaboration

Andreas G Ladurner 1 collaboration

Marcus Buschbeck 1 collaboration

Dorota Kubacka 1 collaboration

Mateusz Kozarski 1 collaboration

Marek R Baranowski 1 collaboration

Radoslaw Wojcik 1 collaboration

Joanna Panecka-Hofman 1 collaboration

Dominika Strzelecka 1 collaboration

Jacek Jemielity 1 collaboration

Joanna Kowalska 1 collaboration

Stefan Bohn 1 collaboration

Florian Beck 1 collaboration

Sven Klumpe 1 collaboration

Günter Pfeifer 1 collaboration

Andreas Bracher 1 collaboration

F Ulrich Hartl 1 collaboration

Wolfgang Baumeister 1 collaboration

Iain Finley Davidson 1 collaboration

Stefano Zamuner 1 collaboration

Florian Patrick Bock 1 collaboration

Jan-Willem Veening 1 collaboration

Paolo De Los Rios 1 collaboration

Jan-Michael Peters 1 collaboration

Cecilia Perez-Borrajero 1 collaboration

Nadezda Podvalnaya 1 collaboration

Kay Holleis 1 collaboration

Raffael Lichtenberger 1 collaboration

Emil Karaulanov 1 collaboration

Bernd Simon 1 collaboration

Janosch Hennig 1 collaboration

René F Ketting 1 collaboration

Katharina Kurscheidt 1 collaboration

Iuliia Iermak 1 collaboration

Evangelos Tatsis 1 collaboration

Yoko Nakamura 1 collaboration

Christian Paetz 1 collaboration

Clare E M Stevenson 1 collaboration

David M Lawson 1 collaboration

Philipp Stephan 1 collaboration

Daniela Winkler 1 collaboration

Hajo Kries 1 collaboration

Veronica Teresa Ober 1 collaboration

Sidney Becker 1 collaboration

Gabriel Moya Munoz 1 collaboration

Jiaolong Wang 1 collaboration

Narcis A Petriman 1 collaboration

Marie B Andersen 1 collaboration

Sagar Bhogaraju 1 collaboration

Melanie Vetter 1 collaboration

Anna Lorentzen 1 collaboration

Jakub Chrustowicz 1 collaboration

Dawafuti Sherpa 1 collaboration

Joan Teyra 1 collaboration

Mun Siong Loke 1 collaboration

Grzegorz M Popowicz 1 collaboration

Sachdev S Sidhu 1 collaboration

Markus Räschle 1 collaboration

Richard A Scheltema 1 collaboration

Mehmet Akdel 1 collaboration

Douglas E V Pires 1 collaboration

Eduard Porta Pardo 1 collaboration

Jürgen Jänes 1 collaboration

Arthur O Zalevsky 1 collaboration

Bálint Mészáros 1 collaboration

Patrick Bryant 1 collaboration

Lydia L Good 1 collaboration

Roman A Laskowski 1 collaboration

Gabriele Pozzati 1 collaboration

Aditi Shenoy 1 collaboration

Wensi Zhu 1 collaboration

Petras Kundrotas 1 collaboration

Victoria Ruiz Serra 1 collaboration

Carlos H M Rodrigues 1 collaboration

Alistair S Dunham 1 collaboration

David Burke 1 collaboration

Neera Borkakoti 1 collaboration

Sameer Velankar 1 collaboration

Adam Frost 1 collaboration

Kresten Lindorff-Larsen 1 collaboration

Alex Bateman 1 collaboration

Andrey V Kajava 1 collaboration

Alfonso Valencia 1 collaboration

Sergey Ovchinnikov 1 collaboration

Janani Durairaj 1 collaboration

David B Ascher 1 collaboration

Janet M Thornton 1 collaboration

Norman E Davey 1 collaboration

Amelie Stein 1 collaboration

Arne Elofsson 1 collaboration

Tristan I Croll 1 collaboration

Pedro Beltrao 1 collaboration

Néstor J Hernández Lozada 1 collaboration

Joshua C Wood 1 collaboration

Ling Chuang 1 collaboration

Maritta Kunert 1 collaboration

Carlos E Rodríguez López 1 collaboration

Dongyan Zhao 1 collaboration

C Robin Buell 1 collaboration

Benjamin R Lichman 1 collaboration

Fabienne Mauxion 1 collaboration

Sevim Ozgur 1 collaboration

Marion Rame 1 collaboration

Jana Albrecht 1 collaboration

Ingmar Schäfer 1 collaboration

Bertrand Séraphin 1 collaboration

William Garland 1 collaboration

Anna Salerno-Kochan 1 collaboration

Leonhard A Karl 1 collaboration

Lorenzo Galanti 1 collaboration

Susanne Cs Bantele 1 collaboration

Felix Metzner 1 collaboration

Barbara Šafarić 1 collaboration

Lional Rajappa 1 collaboration

Benjamin Foster 1 collaboration

Vanessa Borges Pires 1 collaboration

Priyanka Bansal 1 collaboration

Erika Chacin 1 collaboration

Karl E Duderstadt 1 collaboration

Christoph F Kurat 1 collaboration

Till Bartke 1 collaboration

Karl-Peter Hopfner 1 collaboration

Boris Pfander 1 collaboration

Lukas Spiller 1 collaboration

Ramu Manjula 1 collaboration

Franz Leissing 1 collaboration

Priscila Bourilhon 1 collaboration

Dzmitry Sinitski 1 collaboration

Markus Brandhofer 1 collaboration

Sophie Levecque 1 collaboration

Simona Gerra 1 collaboration

Björn Sabelleck 1 collaboration

Lin Zhang 1 collaboration

Regina Feederle 1 collaboration

Andrew Flatley 1 collaboration

Adrian Hoffmann 1 collaboration

Ralph Panstruga 1 collaboration

Jürgen Bernhagen 1 collaboration

Elias Lolis 1 collaboration