Iris Nederlof

Affiliations

Department of Pathology, Amsterdam University Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Division of Molecular Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

Publications (15)

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer.

Breast cancer research : BCR

Avec: Iris Nederlof , Davide De Bortoli , Yacine Bareche , Bastien Nguyen , Michiel de Maaker , Gerrit K J Hooijer , Laurence Buisseret , Marleen Kok , Marcel Smid , Gert G G M Van den Eynden , Arie B Brinkman , Jan Hudecek , Jan Koster , Christos Sotiriou , Denis Larsimont , John W M Martens , Marc J van de Vijver , Hugo M Horlings , Roberto Salgado , Elia Biganzoli , Christine Desmedt

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Study. A Report on Behalf of the International Immuno-Oncology Biomarker Working Group.

Cancers

Avec: Mieke R Van Bockstal , Maxine Cooks , Iris Nederlof , Mariël Brinkhuis , Annemiek Dutman , Monique Koopmans , Loes Kooreman , Bert van der Vegt , Leon Verhoog , Celine Vreuls , Pieter Westenend , Marleen Kok , Paul J van Diest , Inne Nauwelaers , Nele Laudus , Carsten Denkert , David Rimm , Kalliopi P Siziopikou , Scott Ely , Dimitrios Zardavas , Mustimbo Roberts , Giuseppe Floris , Johan Hartman , Balazs Acs , Dieter Peeters , John M S Bartlett , Els Dequeker , Roberto Salgado , Fabiola Giudici , Stefan Michiels , Hugo Horlings , Carolien H M van Deurzen

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Lennart Kester , Danielle Seinstra , Annelot G J van Rossum , Claire Vennin , Marlous Hoogstraat , Daphne van der Velden , Mark Opdam , Erik van Werkhoven , Kerstin Hahn , Iris Nederlof , Ester H Lips , Ingrid A M Mandjes , A Elise van Leeuwen-Stok , Sander Canisius , Harm van Tinteren , Alex L T Imholz , Johanneke E A Portielje , Monique E M M Bos , Sandra D Bakker , Emiel J Rutgers , Hugo M Horlings , Jelle Wesseling , Emile E Voest , Lodewyk F A Wessels , Marleen Kok , Hendrika M Oosterkamp , Alexander van Oudenaarden , Sabine C Linn , Jacco van Rheenen

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer.

Nature communications

Avec: Dora Hammerl , John W M Martens , Mieke Timmermans , Marcel Smid , Anita M Trapman-Jansen , Renée Foekens , Olga I Isaeva , Leonie Voorwerk , Hayri E Balcioglu , Rebecca Wijers , Iris Nederlof , Roberto Salgado , Hugo Horlings , Marleen Kok , Reno Debets

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Nature medicine

Avec: Leonie Voorwerk , Maarten Slagter , Hugo M Horlings , Karolina Sikorska , Koen K van de Vijver , Michiel de Maaker , Iris Nederlof , Roelof J C Kluin , Sarah Warren , SuFey Ong , Terry G Wiersma , Nicola S Russell , Ferry Lalezari , Philip C Schouten , Noor A M Bakker , Steven L C Ketelaars , Dennis Peters , Charlotte A H Lange , Erik van Werkhoven , Harm van Tinteren , Ingrid A M Mandjes , Inge Kemper , Suzanne Onderwater , Myriam Chalabi , Sofie Wilgenhof , John B A G Haanen , Roberto Salgado , Karin E de Visser , Gabe S Sonke , Lodewyk F A Wessels , Sabine C Linn , Ton N Schumacher , Christian U Blank , Marleen Kok

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

NPJ breast cancer

Avec: Jan Hudeček , Leonie Voorwerk , Maartje van Seijen , Iris Nederlof , Michiel de Maaker , Jose van den Berg , Koen K van de Vijver , Karolina Sikorska , Sylvia Adams , Sandra Demaria , Giuseppe Viale , Torsten O Nielsen , Sunil S Badve , Stefan Michiels , William Fraser Symmans , Christos Sotiriou , David L Rimm , Stephen M Hewitt , Carsten Denkert , Sibylle Loibl , Sherene Loi , John M S Bartlett , Giancarlo Pruneri , Deborah A Dillon , Maggie C U Cheang , Andrew Tutt , Jacqueline A Hall , Zuzana Kos , Roberto Salgado , Marleen Kok , Hugo M Horlings , Auteur inconnu

Increased HLA-G Expression in Term Placenta of Women with a History of Recurrent Miscarriage Despite Their Genetic Predisposition to Decreased HLA-G Levels.

International journal of molecular sciences

Avec: Moniek H C Craenmehr , Iris Nederlof , Milo Cao , Jos J M Drabbels , Marijke J Spruyt-Gerritse , Jacqueline D H Anholts , Hanneke M Kapsenberg , Janine A Stegehuis , Carin van der Keur , Esther Fasse , Geert W Haasnoot , Marie-Louise P van der Hoorn , Frans H J Claas , Sebastiaan Heidt , Michael Eikmans

Tipping the balance: inhibitory checkpoints in intestinal homeostasis.

Mucosal immunology

Avec: Maria E Joosse , Iris Nederlof , Lucy S K Walker , Janneke N Samsom

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.

Cancers

Avec: Iris Nederlof , Hugo M Horlings , Christina Curtis , Marleen Kok

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer.

NPJ breast cancer

Avec: I Nederlof , S Hajizadeh , F Sobhani , S E A Raza , K AbdulJabbar , R Harkes , M J van de Vijver , R Salgado , C Desmedt , M Kok , Y Yuan , H M Horlings

DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer.

Medical image analysis

Avec: Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Facts and Hopes in Immunotherapy for Early-Stage Triple-Negative Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Iris Nederlof , Leonie Voorwerk , Marleen Kok

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

bioRxiv : the preprint server for biology

Avec: J Lorenz Rumberger , Noah F Greenwald , Jolene S Ranek , Potchara Boonrat , Cameron Walker , Jannik Franzen , Sricharan Reddy Varra , Alex Kong , Cameron Sowers , Candace C Liu , Inna Averbukh , Hadeesha Piyadasa , Rami Vanguri , Iris Nederlof , Xuefei Julie Wang , David Van Valen , Marleen Kok , Travis J Hollmann , Dagmar Kainmueller , Michael Angelo

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

Nature medicine

Avec: Iris Nederlof , Olga I Isaeva , Manon de Graaf , Robbert C A M Gielen , Noor A M Bakker , Adrianne L Rolfes , Hannah Garner , Bram Boeckx , Joleen J H Traets , Ingrid A M Mandjes , Michiel de Maaker , Thomas van Brussel , Maksim Chelushkin , Elisa Champanhet , Marta Lopez-Yurda , Koen van de Vijver , José G van den Berg , Ingrid Hofland , Natasja Klioueva , Ritse M Mann , Claudette E Loo , Frederieke H van Duijnhoven , Victoria Skinner , Sylvia Luykx , Emile Kerver , Ekaterina Kalashnikova , Marloes G J van Dongen , Gabe S Sonke , Sabine C Linn , Christian U Blank , Karin E de Visser , Roberto Salgado , Lodewyk F A Wessels , Caroline A Drukker , Ton N Schumacher , Hugo M Horlings , Diether Lambrechts , Marleen Kok

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Nature medicine

Réseau de co-auteurs

Marleen Kok 11 collaborations

Hugo M Horlings 7 collaborations

Roberto Salgado 7 collaborations

Michiel de Maaker 5 collaborations

Leonie Voorwerk 5 collaborations

Ingrid A M Mandjes 4 collaborations

Lodewyk F A Wessels 4 collaborations

Sabine C Linn 4 collaborations

Erik van Werkhoven 3 collaborations

Harm van Tinteren 3 collaborations

Karolina Sikorska 3 collaborations

Koen K van de Vijver 3 collaborations

Noor A M Bakker 3 collaborations

Karin E de Visser 3 collaborations

Gabe S Sonke 3 collaborations

Ton N Schumacher 3 collaborations

Christian U Blank 3 collaborations

Marcel Smid 2 collaborations

Christos Sotiriou 2 collaborations

John W M Martens 2 collaborations

Carsten Denkert 2 collaborations

John M S Bartlett 2 collaborations

Stefan Michiels 2 collaborations

Hugo Horlings 2 collaborations

Olga I Isaeva 2 collaborations

Maarten Slagter 2 collaborations

Roelof J C Kluin 2 collaborations

Sarah Warren 2 collaborations

SuFey Ong 2 collaborations

Terry G Wiersma 2 collaborations

Nicola S Russell 2 collaborations

Ferry Lalezari 2 collaborations

Philip C Schouten 2 collaborations

Steven L C Ketelaars 2 collaborations

Dennis Peters 2 collaborations

Charlotte A H Lange 2 collaborations

Inge Kemper 2 collaborations

Suzanne Onderwater 2 collaborations

Myriam Chalabi 2 collaborations

Sofie Wilgenhof 2 collaborations

John B A G Haanen 2 collaborations

Davide De Bortoli 1 collaboration

Yacine Bareche 1 collaboration

Bastien Nguyen 1 collaboration

Gerrit K J Hooijer 1 collaboration

Laurence Buisseret 1 collaboration

Gert G G M Van den Eynden 1 collaboration

Arie B Brinkman 1 collaboration

Jan Hudecek 1 collaboration

Jan Koster 1 collaboration

Denis Larsimont 1 collaboration

Marc J van de Vijver 1 collaboration

Elia Biganzoli 1 collaboration

Christine Desmedt 1 collaboration

Mieke R Van Bockstal 1 collaboration

Maxine Cooks 1 collaboration

Mariël Brinkhuis 1 collaboration

Annemiek Dutman 1 collaboration

Monique Koopmans 1 collaboration

Loes Kooreman 1 collaboration

Bert van der Vegt 1 collaboration

Leon Verhoog 1 collaboration

Celine Vreuls 1 collaboration

Pieter Westenend 1 collaboration

Paul J van Diest 1 collaboration

Inne Nauwelaers 1 collaboration

Nele Laudus 1 collaboration

David Rimm 1 collaboration

Kalliopi P Siziopikou 1 collaboration

Scott Ely 1 collaboration

Dimitrios Zardavas 1 collaboration

Mustimbo Roberts 1 collaboration

Giuseppe Floris 1 collaboration

Johan Hartman 1 collaboration

Balazs Acs 1 collaboration

Dieter Peeters 1 collaboration

Els Dequeker 1 collaboration

Fabiola Giudici 1 collaboration

Carolien H M van Deurzen 1 collaboration

Lennart Kester 1 collaboration

Danielle Seinstra 1 collaboration

Annelot G J van Rossum 1 collaboration

Claire Vennin 1 collaboration

Marlous Hoogstraat 1 collaboration

Daphne van der Velden 1 collaboration

Mark Opdam 1 collaboration

Kerstin Hahn 1 collaboration

Ester H Lips 1 collaboration

A Elise van Leeuwen-Stok 1 collaboration

Sander Canisius 1 collaboration

Alex L T Imholz 1 collaboration

Johanneke E A Portielje 1 collaboration

Monique E M M Bos 1 collaboration

Sandra D Bakker 1 collaboration

Emiel J Rutgers 1 collaboration

Jelle Wesseling 1 collaboration

Emile E Voest 1 collaboration

Hendrika M Oosterkamp 1 collaboration

Alexander van Oudenaarden 1 collaboration

Jacco van Rheenen 1 collaboration

Dora Hammerl 1 collaboration

Mieke Timmermans 1 collaboration

Anita M Trapman-Jansen 1 collaboration

Renée Foekens 1 collaboration

Hayri E Balcioglu 1 collaboration

Rebecca Wijers 1 collaboration

Reno Debets 1 collaboration

Jan Hudeček 1 collaboration

Maartje van Seijen 1 collaboration

Jose van den Berg 1 collaboration

Sylvia Adams 1 collaboration

Sandra Demaria 1 collaboration

Giuseppe Viale 1 collaboration

Torsten O Nielsen 1 collaboration

Sunil S Badve 1 collaboration

William Fraser Symmans 1 collaboration

David L Rimm 1 collaboration

Stephen M Hewitt 1 collaboration

Sibylle Loibl 1 collaboration

Sherene Loi 1 collaboration

Giancarlo Pruneri 1 collaboration

Deborah A Dillon 1 collaboration

Maggie C U Cheang 1 collaboration

Andrew Tutt 1 collaboration

Jacqueline A Hall 1 collaboration

Zuzana Kos 1 collaboration

None None 1 collaboration

Moniek H C Craenmehr 1 collaboration

Milo Cao 1 collaboration

Jos J M Drabbels 1 collaboration

Marijke J Spruyt-Gerritse 1 collaboration

Jacqueline D H Anholts 1 collaboration

Hanneke M Kapsenberg 1 collaboration

Janine A Stegehuis 1 collaboration

Carin van der Keur 1 collaboration

Esther Fasse 1 collaboration

Geert W Haasnoot 1 collaboration

Marie-Louise P van der Hoorn 1 collaboration

Frans H J Claas 1 collaboration

Sebastiaan Heidt 1 collaboration

Michael Eikmans 1 collaboration

Maria E Joosse 1 collaboration

Lucy S K Walker 1 collaboration

Janneke N Samsom 1 collaboration

Christina Curtis 1 collaboration

I Nederlof 1 collaboration

S Hajizadeh 1 collaboration

F Sobhani 1 collaboration

S E A Raza 1 collaboration

K AbdulJabbar 1 collaboration

R Harkes 1 collaboration

M J van de Vijver 1 collaboration

R Salgado 1 collaboration

C Desmedt 1 collaboration

M Kok 1 collaboration

Y Yuan 1 collaboration

H M Horlings 1 collaboration

Yoni Schirris 1 collaboration

Efstratios Gavves 1 collaboration

Hugo Mark Horlings 1 collaboration

Jonas Teuwen 1 collaboration

J Lorenz Rumberger 1 collaboration

Noah F Greenwald 1 collaboration

Jolene S Ranek 1 collaboration

Potchara Boonrat 1 collaboration

Cameron Walker 1 collaboration

Jannik Franzen 1 collaboration

Sricharan Reddy Varra 1 collaboration

Alex Kong 1 collaboration

Cameron Sowers 1 collaboration

Candace C Liu 1 collaboration

Inna Averbukh 1 collaboration

Hadeesha Piyadasa 1 collaboration

Rami Vanguri 1 collaboration

Xuefei Julie Wang 1 collaboration

David Van Valen 1 collaboration

Travis J Hollmann 1 collaboration

Dagmar Kainmueller 1 collaboration

Michael Angelo 1 collaboration

Manon de Graaf 1 collaboration

Robbert C A M Gielen 1 collaboration

Adrianne L Rolfes 1 collaboration

Hannah Garner 1 collaboration

Bram Boeckx 1 collaboration

Joleen J H Traets 1 collaboration

Thomas van Brussel 1 collaboration

Maksim Chelushkin 1 collaboration

Elisa Champanhet 1 collaboration

Marta Lopez-Yurda 1 collaboration

Koen van de Vijver 1 collaboration

José G van den Berg 1 collaboration

Ingrid Hofland 1 collaboration

Natasja Klioueva 1 collaboration

Ritse M Mann 1 collaboration

Claudette E Loo 1 collaboration

Frederieke H van Duijnhoven 1 collaboration

Victoria Skinner 1 collaboration

Sylvia Luykx 1 collaboration

Emile Kerver 1 collaboration

Ekaterina Kalashnikova 1 collaboration

Marloes G J van Dongen 1 collaboration

Caroline A Drukker 1 collaboration

Diether Lambrechts 1 collaboration