Inga Nehlmeier

Affiliations

Infection Biology Unit, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany.

Publications (27)

SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination.

Cell reports

Avec: Prerna Arora , Amy Kempf , Inga Nehlmeier , Luise Graichen , Martin S Winkler , Martin Lier , Sebastian Schulz , Hans-Martin Jäck , Anne Cossmann , Metodi V Stankov , Georg M N Behrens , Stefan Pöhlmann , Markus Hoffmann

Native and activated antithrombin inhibits TMPRSS2 activity and SARS-CoV-2 infection.

Journal of medical virology

Avec: Lukas Wettstein , Patrick Immenschuh , Tatjana Weil , Carina Conzelmann , Yasser Almeida-Hernández , Markus Hoffmann , Amy Kempf , Inga Nehlmeier , Rishikesh Lotke , Moritz Petersen , Steffen Stenger , Frank Kirchhoff , Daniel Sauter , Stefan Pöhlmann , Elsa Sanchez-Garcia , Jan Münch

TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection.

Viruses

Avec: Kristin Metzdorf , Henning Jacobsen , Marina C Greweling-Pils , Markus Hoffmann , Tatjana Lüddecke , Felicitas Miller , Lars Melcher , Amy M Kempf , Inga Nehlmeier , Dunja Bruder , Marek Widera , Sandra Ciesek , Stefan Pöhlmann , Luka Čičin-Šain

H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice.

Virology journal

Avec: Ruth Lydia Olga Lambertz , Ingo Gerhauser , Inga Nehlmeier , Sabine Gärtner , Michael Winkler , Sarah Rebecca Leist , Heike Kollmus , Stefan Pöhlmann , Klaus Schughart

No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2.

Cellular & molecular immunology

Avec: Prerna Arora , Amy Kempf , Inga Nehlmeier , Luise Graichen , Martin S Winkler , Martin Lier , Sebastian Schulz , Hans-Martin Jäck , Stefan Pöhlmann , Markus Hoffmann

SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination.

Cell reports

Avec: Markus Hoffmann , Heike Hofmann-Winkler , Nadine Krüger , Amy Kempf , Inga Nehlmeier , Luise Graichen , Prerna Arora , Anzhalika Sidarovich , Anna-Sophie Moldenhauer , Martin S Winkler , Sebastian Schulz , Hans-Martin Jäck , Metodi V Stankov , Georg M N Behrens , Stefan Pöhlmann

Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein.

JACS Au

Avec: Darshita Budhadev , James Hooper , Cheila Rocha , Inga Nehlmeier , Amy Madeleine Kempf , Markus Hoffmann , Nadine Krüger , Dejian Zhou , Stefan Pöhlmann , Yuan Guo

Omicron subvariant BA.5 efficiently infects lung cells.

Nature communications

Avec: Markus Hoffmann , Lok-Yin Roy Wong , Prerna Arora , Lu Zhang , Cheila Rocha , Abby Odle , Inga Nehlmeier , Amy Kempf , Anja Richter , Nico Joel Halwe , Jacob Schön , Lorenz Ulrich , Donata Hoffmann , Martin Beer , Christian Drosten , Stanley Perlman , Stefan Pöhlmann

Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.

PloS one

Avec: Teresa Plegge , Martin Spiegel , Nadine Krüger , Inga Nehlmeier , Michael Winkler , Mariana González Hernández , Stefan Pöhlmann

Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y.

Biochimie

Avec: Bernardo R Oliveira , Inga Nehlmeier , Amy Madeleine Kempf , Vaishnavi Venugopalan , Maren Rehders , Marianne E P Ceniza , Pedro A de T P V Cavalcanti , Markus Hoffmann , Stefan Pöhlmann , Klaudia Brix

The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant.

International journal of molecular sciences

Avec: Prerna Arora , Lu Zhang , Cheila Rocha , Luise Graichen , Inga Nehlmeier , Amy Kempf , Anne Cossmann , Gema Morillas Ramos , Eva Baier , Björn Tampe , Onnen Moerer , Steffen Dickel , Martin S Winkler , Georg M N Behrens , Stefan Pöhlmann , Markus Hoffmann

Probing scaffold size effects on multivalent lectin-glycan binding affinity, thermodynamics and antiviral properties using polyvalent glycan-gold nanoparticles.

Nanoscale

Avec: Rahman Basaran , Darshita Budhadev , Amy Kempf , Inga Nehlmeier , Nicole Hondow , Stefan Pöhlmann , Yuan Guo , Dejian Zhou

Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells.

Journal of virology

Avec: Markus Hoffmann , Hannah Kleine-Weber , Luise Graichen , Inga Nehlmeier , Amy Kempf , Anna-Sophie Moldenhauer , Elisabeth Braun , Abdullah M Assiri , Frank Kirchhoff , Daniel Sauter , Khaled R Alkharsah , Stefan Pöhlmann

Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques.

PloS one

Avec: Michael Winkler , Sabine Gärtner , Lara Markus , Markus Hoffmann , Inga Nehlmeier , Michael Krawczak , Ulrike Sauermann , Stefan Pöhlmann

Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.

Journal of virology

Avec: Markus Hoffmann , Inga Nehlmeier , Constantin Brinkmann , Verena Krähling , Laura Behner , Anna-Sophie Moldenhauer , Nadine Krüger , Julia Nehls , Michael Schindler , Thomas Hoenen , Andrea Maisner , Stephan Becker , Stefan Pöhlmann

B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination.

Cell reports

Avec: Prerna Arora , Anzhalika Sidarovich , Nadine Krüger , Amy Kempf , Inga Nehlmeier , Luise Graichen , Anna-Sophie Moldenhauer , Martin S Winkler , Sebastian Schulz , Hans-Martin Jäck , Metodi V Stankov , Georg M N Behrens , Stefan Pöhlmann , Markus Hoffmann

Humoral and Cellular Immune Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Human Coronaviruses After Single BNT162b2 Vaccination.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Metodi V Stankov , Anne Cossmann , Agnes Bonifacius , Alexandra Dopfer-Jablonka , Gema Morillas Ramos , Nina Gödecke , Anna Zychlinsky Scharff , Christine Happle , Anna-Lena Boeck , Anh Thu Tran , Isabell Pink , Marius M Hoeper , Rainer Blasczyk , Martin S Winkler , Inga Nehlmeier , Amy Kempf , Heike Hofmann-Winkler , Markus Hoffmann , Britta Eiz-Vesper , Stefan Pöhlmann , Georg M N Behrens

Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy.

mBio

Avec: Markus Hoffmann , Anzhalika Sidarovich , Prerna Arora , Nadine Krüger , Inga Nehlmeier , Amy Kempf , Luise Graichen , Martin S Winkler , Daniela Niemeyer , Christine Goffinet , Christian Drosten , Sebastian Schulz , Hans-Martin Jäck , Stefan Pöhlmann

Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity.

PLoS pathogens

Avec: Christina B Karsten , Falk F R Buettner , Samanta Cajic , Inga Nehlmeier , Berit Roshani , Antonina Klippert , Ulrike Sauermann , Nicole Stolte-Leeb , Udo Reichl , Rita Gerardy-Schahn , Erdmann Rapp , Christiane Stahl-Hennig , Stefan Pöhlmann

Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways.

Journal of virology

Avec: Manon Laporte , Annelies Stevaert , Valerie Raeymaekers , Talitha Boogaerts , Inga Nehlmeier , Winston Chiu , Mohammed Benkheil , Bart Vanaudenaerde , Stefan Pöhlmann , Lieve Naesens

Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis.

The Journal of general virology

Avec: Ruth L O Lambertz , Ingo Gerhauser , Inga Nehlmeier , Sarah R Leist , Heike Kollmus , Stefan Pöhlmann , Klaus Schughart

Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin-Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly.

Journal of the American Chemical Society

Avec: Darshita Budhadev , Emma Poole , Inga Nehlmeier , Yuanyuan Liu , James Hooper , Elizabeth Kalverda , Uchangi Satyaprasad Akshath , Nicole Hondow , W Bruce Turnbull , Stefan Pöhlmann , Yuan Guo , Dejian Zhou

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic.

Cell

Avec: Markus Hoffmann , Nadine Krüger , Sebastian Schulz , Anne Cossmann , Cheila Rocha , Amy Kempf , Inga Nehlmeier , Luise Graichen , Anna-Sophie Moldenhauer , Martin S Winkler , Martin Lier , Alexandra Dopfer-Jablonka , Hans-Martin Jäck , Georg M N Behrens , Stefan Pöhlmann

Polyvalent Glycomimetic-Gold Nanoparticles Revealing Critical Roles of Glycan Display on Multivalent Lectin-Glycan Interaction Biophysics and Antiviral Properties.

JACS Au

Avec: Xinyu Ning , Darshita Budhadev , Sara Pollastri , Inga Nehlmeier , Amy Kempf , Iain Manfield , W Bruce Turnbull , Stefan Pöhlmann , Anna Bernardi , Xin Li , Yuan Guo , Dejian Zhou

Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage.

Vaccines

Avec: Lu Zhang , Alexandra Dopfer-Jablonka , Inga Nehlmeier , Amy Kempf , Luise Graichen , Noemí Calderón Hampel , Anne Cossmann , Metodi V Stankov , Gema Morillas Ramos , Sebastian R Schulz , Hans-Martin Jäck , Georg M N Behrens , Stefan Pöhlmann , Markus Hoffmann

Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1.

Viruses

Avec: Anzhalika Sidarovich , Nadine Krüger , Cheila Rocha , Luise Graichen , Amy Kempf , Inga Nehlmeier , Martin Lier , Anne Cossmann , Metodi V Stankov , Sebastian R Schulz , Georg M N Behrens , Hans-Martin Jäck , Stefan Pöhlmann , Markus Hoffmann

SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.

Cell

Avec: Lu Zhang , Amy Kempf , Inga Nehlmeier , Anne Cossmann , Anja Richter , Najat Bdeir , Luise Graichen , Anna-Sophie Moldenhauer , Alexandra Dopfer-Jablonka , Metodi V Stankov , Etienne Simon-Loriere , Sebastian R Schulz , Hans-Martin Jäck , Luka Čičin-Šain , Georg M N Behrens , Christian Drosten , Markus Hoffmann , Stefan Pöhlmann

Réseau de co-auteurs

Stefan Pöhlmann 27 collaborations

Markus Hoffmann 19 collaborations

Amy Kempf 16 collaborations

Luise Graichen 11 collaborations

Hans-Martin Jäck 9 collaborations

Georg M N Behrens 9 collaborations

Martin S Winkler 8 collaborations

Nadine Krüger 8 collaborations

Prerna Arora 7 collaborations

Anne Cossmann 7 collaborations

Metodi V Stankov 7 collaborations

Sebastian Schulz 6 collaborations

Anna-Sophie Moldenhauer 6 collaborations

Cheila Rocha 5 collaborations

Martin Lier 4 collaborations

Anzhalika Sidarovich 4 collaborations

Darshita Budhadev 4 collaborations

Dejian Zhou 4 collaborations

Yuan Guo 4 collaborations

Lu Zhang 4 collaborations

Alexandra Dopfer-Jablonka 4 collaborations

Michael Winkler 3 collaborations

Christian Drosten 3 collaborations

Gema Morillas Ramos 3 collaborations

Sebastian R Schulz 3 collaborations

Frank Kirchhoff 2 collaborations

Daniel Sauter 2 collaborations

Luka Čičin-Šain 2 collaborations

Ingo Gerhauser 2 collaborations

Sabine Gärtner 2 collaborations

Heike Kollmus 2 collaborations

Klaus Schughart 2 collaborations

Heike Hofmann-Winkler 2 collaborations

James Hooper 2 collaborations

Amy Madeleine Kempf 2 collaborations

Anja Richter 2 collaborations

Nicole Hondow 2 collaborations

Ulrike Sauermann 2 collaborations

W Bruce Turnbull 2 collaborations

Lukas Wettstein 1 collaboration

Patrick Immenschuh 1 collaboration

Tatjana Weil 1 collaboration

Carina Conzelmann 1 collaboration

Yasser Almeida-Hernández 1 collaboration

Rishikesh Lotke 1 collaboration

Moritz Petersen 1 collaboration

Steffen Stenger 1 collaboration

Elsa Sanchez-Garcia 1 collaboration

Jan Münch 1 collaboration

Kristin Metzdorf 1 collaboration

Henning Jacobsen 1 collaboration

Marina C Greweling-Pils 1 collaboration

Tatjana Lüddecke 1 collaboration

Felicitas Miller 1 collaboration

Lars Melcher 1 collaboration

Amy M Kempf 1 collaboration

Dunja Bruder 1 collaboration

Marek Widera 1 collaboration

Sandra Ciesek 1 collaboration

Ruth Lydia Olga Lambertz 1 collaboration

Sarah Rebecca Leist 1 collaboration

Lok-Yin Roy Wong 1 collaboration

Abby Odle 1 collaboration

Nico Joel Halwe 1 collaboration

Jacob Schön 1 collaboration

Lorenz Ulrich 1 collaboration

Donata Hoffmann 1 collaboration

Martin Beer 1 collaboration

Stanley Perlman 1 collaboration

Teresa Plegge 1 collaboration

Martin Spiegel 1 collaboration

Mariana González Hernández 1 collaboration

Bernardo R Oliveira 1 collaboration

Vaishnavi Venugopalan 1 collaboration

Maren Rehders 1 collaboration

Marianne E P Ceniza 1 collaboration

Pedro A de T P V Cavalcanti 1 collaboration

Klaudia Brix 1 collaboration

Eva Baier 1 collaboration

Björn Tampe 1 collaboration

Onnen Moerer 1 collaboration

Steffen Dickel 1 collaboration

Rahman Basaran 1 collaboration

Hannah Kleine-Weber 1 collaboration

Elisabeth Braun 1 collaboration

Abdullah M Assiri 1 collaboration

Khaled R Alkharsah 1 collaboration

Lara Markus 1 collaboration

Michael Krawczak 1 collaboration

Constantin Brinkmann 1 collaboration

Verena Krähling 1 collaboration

Laura Behner 1 collaboration

Julia Nehls 1 collaboration

Michael Schindler 1 collaboration

Thomas Hoenen 1 collaboration

Andrea Maisner 1 collaboration

Stephan Becker 1 collaboration

Agnes Bonifacius 1 collaboration

Nina Gödecke 1 collaboration

Anna Zychlinsky Scharff 1 collaboration

Christine Happle 1 collaboration

Anna-Lena Boeck 1 collaboration

Anh Thu Tran 1 collaboration

Isabell Pink 1 collaboration

Marius M Hoeper 1 collaboration

Rainer Blasczyk 1 collaboration

Britta Eiz-Vesper 1 collaboration

Daniela Niemeyer 1 collaboration

Christine Goffinet 1 collaboration

Christina B Karsten 1 collaboration

Falk F R Buettner 1 collaboration

Samanta Cajic 1 collaboration

Berit Roshani 1 collaboration

Antonina Klippert 1 collaboration

Nicole Stolte-Leeb 1 collaboration

Udo Reichl 1 collaboration

Rita Gerardy-Schahn 1 collaboration

Erdmann Rapp 1 collaboration

Christiane Stahl-Hennig 1 collaboration

Manon Laporte 1 collaboration

Annelies Stevaert 1 collaboration

Valerie Raeymaekers 1 collaboration

Talitha Boogaerts 1 collaboration

Winston Chiu 1 collaboration

Mohammed Benkheil 1 collaboration

Bart Vanaudenaerde 1 collaboration

Lieve Naesens 1 collaboration

Ruth L O Lambertz 1 collaboration

Sarah R Leist 1 collaboration

Emma Poole 1 collaboration

Yuanyuan Liu 1 collaboration

Elizabeth Kalverda 1 collaboration

Uchangi Satyaprasad Akshath 1 collaboration

Xinyu Ning 1 collaboration

Sara Pollastri 1 collaboration

Iain Manfield 1 collaboration

Anna Bernardi 1 collaboration

Xin Li 1 collaboration

Noemí Calderón Hampel 1 collaboration

Najat Bdeir 1 collaboration

Etienne Simon-Loriere 1 collaboration