Ignacio Rego-Pérez

Affiliations

I. Rego-Pérez, PhD, INIBIC-Hospital Universitario A Coruña (CHUAC), Rheumatology Division.

Publications (23)

Relationship Between the Dynamics of Telomere Loss in Peripheral Blood Leukocytes From Knee Osteoarthritis Patients and Mitochondrial DNA Haplogroups.

The Journal of rheumatology

Avec: Rebeca Guillén Fajardo , Fátima Otero Fariña , Alejandro Mosquera Rey , Ignacio Rego-Pérez , Francisco J Blanco , José Luis Fernández García

Design of a digital-PCR assay to quantify fragmented human mitochondrial DNA.

Environmental and molecular mutagenesis

Avec: Alejandro Mosquera , Rebeca Guillén , Fátima Otero , Ignacio Rego-Pérez , Francisco J Blanco , José Luis Fernández

Mitochondrial Role on Cellular Apoptosis, Autophagy, and Senescence during Osteoarthritis Pathogenesis.

Cells

Avec: Andrea Dalmao-Fernández , Tamara Hermida-Gómez , Uxia Nogueira-Recalde , Ignacio Rego-Pérez , Francisco J Blanco-Garcia , Mercedes Fernández-Moreno

Differential Association of Mitochondrial DNA Haplogroups J and H With the Methylation Status of Articular Cartilage: Potential Role in Apoptosis and Metabolic and Developmental Processes.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Estefanía Cortés-Pereira , Juan Fernández-Tajes , Mercedes Fernández-Moreno , María E Vázquez-Mosquera , Sara Relaño , Paula Ramos-Louro , Alejandro Durán-Sotuela , Andrea Dalmao-Fernández , Natividad Oreiro , Francisco J Blanco , Ignacio Rego-Pérez

Mitochondrial DNA from osteoarthritic patients drives functional impairment of mitochondrial activity: a study on transmitochondrial cybrids.

Cytotherapy

Avec: Andrea Dalmao-Fernández , Tamara Hermida-Gómez , Jenny Lund , Maria E Vazquez-Mosquera , Ignacio Rego-Pérez , Rafael Garesse , Francisco J Blanco , Mercedes Fernández-Moreno

PROCOAC (PROspective COhort of A Coruña) description: Spanish prospective cohort to study osteoarthritis.

Reumatologia clinica

Avec: Natividad Oreiro-Villar , Ana C Raga , Ignacio Rego-Pérez , Sonia Pértega , Maite Silva-Diaz , Mercedes Freire , Carlos Fernández-López , Francisco J Blanco

Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort.

Scientific reports

Avec: Rebeca Guillén , Fátima Otero , Alejandro Mosquera , María Vázquez-Mosquera , Ignacio Rego-Pérez , Francisco J Blanco , José Luis Fernández

PROCOAC (PROspective COhort of A Coruña) description: Spanish prospective cohort to study osteoarthritis.

Reumatologia clinica

Avec: Natividad Oreiro-Villar , Ana C Raga , Ignacio Rego-Pérez , Sonia Pértega , Maite Silva-Diaz , Mercedes Freire , Carlos Fernández-López , Francisco J Blanco

A clinical model including protein biomarkers predicts radiographic knee osteoarthritis: a prospective study using data from the Osteoarthritis Initiative.

Osteoarthritis and cartilage

Avec: L Lourido , V Balboa-Barreiro , C Ruiz-Romero , I Rego-Pérez , M Camacho-Encina , R Paz-González , V Calamia , N Oreiro , P Nilsson , F J Blanco

Impaired Metabolic Flexibility in the Osteoarthritis Process: A Study on Transmitochondrial Cybrids.

Cells

Avec: Andrea Dalmao-Fernández , Jenny Lund , Tamara Hermida-Gómez , María E Vazquez-Mosquera , Ignacio Rego-Pérez , Francisco J Blanco , Mercedes Fernández-Moreno

Oleate Prevents Palmitate-Induced Mitochondrial Dysfunction in Chondrocytes.

Frontiers in physiology

Avec: Maria Eugenia Vázquez-Mosquera , Mercedes Fernández-Moreno , Estefanía Cortés-Pereira , Sara Relaño , Andrea Dalmao-Fernández , Paula Ramos-Louro , Alejandro Durán Sotuela , Ignacio Rego-Pérez , Francisco J Blanco

mtDNA variability determines spontaneous joint aging damage in a conplastic mouse model.

Aging

Avec: Morena Scotece , Carlos Vaamonde-García , Ana Victoria Lechuga-Vieco , Alberto Centeno Cortés , María Concepción Jiménez Gómez , Purificación Filgueira-Fernández , Ignacio Rego-Pérez , José Antonio Enríquez , Francisco J Blanco

Mitonuclear epistasis involving TP63 and haplogroup Uk: Risk of rapid progression of knee OA in patients from the OAI.

Osteoarthritis and cartilage

Avec: Alejandro Durán-Sotuela , Natividad Oreiro , Mercedes Fernández-Moreno , Jorge Vázquez-García , Sara Relaño-Fernández , Vanesa Balboa-Barreiro , Francisco J Blanco , Ignacio Rego-Pérez

Metabolic syndrome is not associated with erosive hand osteoarthritis: a cross-sectional study using data from the PROCOAC cohort.

Scientific reports

Avec: Maite Silva-Díaz , Sonia Pértega-Díaz , Vanesa Balboa-Barreiro , Carlos M Tilve-Álvarez , Ana Raga-Sivira , Ignacio Rego-Pérez , Francisco J Blanco , Natividad Oreiro

An exploratory analysis of associations of genetic variation with the efficacy of tocilizumab in severe COVID-19 patients. A pharmacogenetic study based on next-generation sequencing.

Frontiers in pharmacology

Avec: Alejandro Durán-Sotuela , Jorge Vázquez-García , Sara Relaño-Fernández , Vanesa Balboa-Barreiro , Juan Fernández-Tajes , Francisco J Blanco , Ignacio Rego-Pérez

Mitochondrial Genetics and Epigenetics in Osteoarthritis.

Frontiers in genetics

Avec: Ignacio Rego-Pérez , Alejandro Durán-Sotuela , Paula Ramos-Louro , Francisco J Blanco

Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis.

Therapeutic advances in chronic disease

Avec: Francisco J Blanco , María Camacho-Encina , Lucía González-Rodríguez , Ignacio Rego-Pérez , Jesús Mateos , Patricia Fernández-Puente , Lucía Lourido , Beatriz Rocha , Florencia Picchi , María T Silva-Díaz , Marta Herrero , Helena Martínez , Josep Verges , Cristina Ruiz-Romero , Valentina Calamia

Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis.

Environmental and molecular mutagenesis

Avec: Alejandro Mosquera , Ignacio Rego-Pérez , Francisco J Blanco , José Luis Fernández

Genetic biomarkers in osteoarthritis: a quick overview.

Faculty reviews

Avec: Ignacio Rego-Pérez , Alejandro Durán-Sotuela , Paula Ramos-Louro , Francisco J Blanco

Is osteoarthritis a mitochondrial disease? What is the evidence.

Current opinion in rheumatology

Avec: Mercedes Fernández-Moreno , Ignacio Rego-Pérez , Francisco J Blanco

Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis.

Scientific reports

Avec: Morena Scotece , Ignacio Rego-Pérez , Ana Victoria Lechuga-Vieco , Alberto Centeno Cortés , María Concepción Jiménez-Gómez , Purificación Filgueira-Fernández , Carlos Vaamonde-García , José Antonio Enríquez , Francisco J Blanco

mtDNA haplogroup A enhances the effect of obesity on the risk of knee OA in a Mexican population.

Scientific reports

Avec: Paula Ramos-Louro , Rubén Daniel Arellano Pérez Vertti , Alberto López Reyes , Gabriela Angélica Martínez-Nava , Rolando Espinosa , Carlos Pineda , Faviel Francisco González Galarza , Rafael Argüello Astorga , Lizette Sarai Aguilar Muñiz , Fernando Hernández Terán , Nancy Marbella Parra Torres , Alejandro Durán Sotuela , Mercedes Fernández-Moreno , Vanesa Balboa Barreiro , Francisco J Blanco , Ignacio Rego-Pérez

Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers.

BMC medicine

Avec: Hossein Bonakdari , Jean-Pierre Pelletier , Francisco J Blanco , Ignacio Rego-Pérez , Alejandro Durán-Sotuela , Dawn Aitken , Graeme Jones , Flavia Cicuttini , Afshin Jamshidi , François Abram , Johanne Martel-Pelletier

Réseau de co-auteurs

Francisco J Blanco 21 collaborations

Mercedes Fernández-Moreno 8 collaborations

Alejandro Durán-Sotuela 6 collaborations

Andrea Dalmao-Fernández 5 collaborations

Paula Ramos-Louro 5 collaborations

Alejandro Mosquera 3 collaborations

José Luis Fernández 3 collaborations

Tamara Hermida-Gómez 3 collaborations

Natividad Oreiro 3 collaborations

Vanesa Balboa-Barreiro 3 collaborations

Rebeca Guillén 2 collaborations

Fátima Otero 2 collaborations

Estefanía Cortés-Pereira 2 collaborations

Juan Fernández-Tajes 2 collaborations

Sara Relaño 2 collaborations

Jenny Lund 2 collaborations

Natividad Oreiro-Villar 2 collaborations

Ana C Raga 2 collaborations

Sonia Pértega 2 collaborations

Maite Silva-Diaz 2 collaborations

Mercedes Freire 2 collaborations

Carlos Fernández-López 2 collaborations

Alejandro Durán Sotuela 2 collaborations

Morena Scotece 2 collaborations

Carlos Vaamonde-García 2 collaborations

Ana Victoria Lechuga-Vieco 2 collaborations

Alberto Centeno Cortés 2 collaborations

Purificación Filgueira-Fernández 2 collaborations

José Antonio Enríquez 2 collaborations

Jorge Vázquez-García 2 collaborations

Sara Relaño-Fernández 2 collaborations

Rebeca Guillén Fajardo 1 collaboration

Fátima Otero Fariña 1 collaboration

Alejandro Mosquera Rey 1 collaboration

José Luis Fernández García 1 collaboration

Uxia Nogueira-Recalde 1 collaboration

Francisco J Blanco-Garcia 1 collaboration

María E Vázquez-Mosquera 1 collaboration

Maria E Vazquez-Mosquera 1 collaboration

Rafael Garesse 1 collaboration

María Vázquez-Mosquera 1 collaboration

L Lourido 1 collaboration

V Balboa-Barreiro 1 collaboration

C Ruiz-Romero 1 collaboration

I Rego-Pérez 1 collaboration

M Camacho-Encina 1 collaboration

R Paz-González 1 collaboration

V Calamia 1 collaboration

N Oreiro 1 collaboration

P Nilsson 1 collaboration

F J Blanco 1 collaboration

María E Vazquez-Mosquera 1 collaboration

Maria Eugenia Vázquez-Mosquera 1 collaboration

María Concepción Jiménez Gómez 1 collaboration

Maite Silva-Díaz 1 collaboration

Sonia Pértega-Díaz 1 collaboration

Carlos M Tilve-Álvarez 1 collaboration

Ana Raga-Sivira 1 collaboration

María Camacho-Encina 1 collaboration

Lucía González-Rodríguez 1 collaboration

Jesús Mateos 1 collaboration

Patricia Fernández-Puente 1 collaboration

Lucía Lourido 1 collaboration

Beatriz Rocha 1 collaboration

Florencia Picchi 1 collaboration

María T Silva-Díaz 1 collaboration

Marta Herrero 1 collaboration

Helena Martínez 1 collaboration

Josep Verges 1 collaboration

Cristina Ruiz-Romero 1 collaboration

Valentina Calamia 1 collaboration

María Concepción Jiménez-Gómez 1 collaboration

Rubén Daniel Arellano Pérez Vertti 1 collaboration

Alberto López Reyes 1 collaboration

Gabriela Angélica Martínez-Nava 1 collaboration

Rolando Espinosa 1 collaboration

Carlos Pineda 1 collaboration

Faviel Francisco González Galarza 1 collaboration

Rafael Argüello Astorga 1 collaboration

Lizette Sarai Aguilar Muñiz 1 collaboration

Fernando Hernández Terán 1 collaboration

Nancy Marbella Parra Torres 1 collaboration

Vanesa Balboa Barreiro 1 collaboration

Hossein Bonakdari 1 collaboration

Jean-Pierre Pelletier 1 collaboration

Dawn Aitken 1 collaboration

Graeme Jones 1 collaboration

Flavia Cicuttini 1 collaboration

Afshin Jamshidi 1 collaboration

François Abram 1 collaboration

Johanne Martel-Pelletier 1 collaboration