Holly J Garringer

Affiliations

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.

Publications (25)

Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.

Acta neuropathologica

Avec: Yang Shi , Alexey G Murzin , Benjamin Falcon , Alexander Epstein , Jonathan Machin , Paul Tempest , Kathy L Newell , Ruben Vidal , Holly J Garringer , Naruhiko Sahara , Makoto Higuchi , Bernardino Ghetti , Ming-Kuei Jang , Sjors H W Scheres , Michel Goedert

Cryo-EM structures of amyloid-β 42 filaments from human brains.

Science (New York, N.Y.)

Avec: Yang Yang , Diana Arseni , Wenjuan Zhang , Melissa Huang , Sofia Lövestam , Manuel Schweighauser , Abhay Kotecha , Alexey G Murzin , Sew Y Peak-Chew , Jennifer Macdonald , Isabelle Lavenir , Holly J Garringer , Ellen Gelpi , Kathy L Newell , Gabor G Kovacs , Ruben Vidal , Bernardino Ghetti , Benjamin Ryskeldi-Falcon , Sjors H W Scheres , Michel Goedert

Cryo-EM structures of cotton wool plaques' amyloid β and of tau filaments in dominantly inherited Alzheimer disease.

Acta neuropathologica

Avec: Md Rejaul Hoq , Anllely Fernandez , Frank S Vago , Grace I Hallinan , Sakshibeedu R Bharath , Daoyi Li , Kadir A Ozcan , Holly J Garringer , Wen Jiang , Ruben Vidal , Bernardino Ghetti

Structure-based classification of tauopathies.

Nature

Avec: Yang Shi , Wenjuan Zhang , Yang Yang , Alexey G Murzin , Benjamin Falcon , Abhay Kotecha , Mike van Beers , Airi Tarutani , Fuyuki Kametani , Holly J Garringer , Ruben Vidal , Grace I Hallinan , Tammaryn Lashley , Yuko Saito , Shigeo Murayama , Mari Yoshida , Hidetomo Tanaka , Akiyoshi Kakita , Takeshi Ikeuchi , Andrew C Robinson , David M A Mann , Gabor G Kovacs , Tamas Revesz , Bernardino Ghetti , Masato Hasegawa , Michel Goedert , Sjors H W Scheres

Design and baseline characteristics of the Cognitive and Aerobic Resilience for the Brain (CARB) study.

Contemporary clinical trials

Avec: Joyce W Tam , Kiran Khurshid , Briana Sprague , Daniel O Clark , Huiping Xu , Lyndsi R Moser , Douglas K Miller , Robert Considine , Christopher M Callahan , Holly J Garringer , Daniel Rexroth , Frederick W Unverzagt

Detection of TDP-43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Elena Fontana , Matilde Bongianni , Alberto Benussi , Erika Bronzato , Carlo Scialo , Luca Sacchetto , Annachiara Cagnin , Santina Castriciano , Emanuele Buratti , Fabrizio Gardoni , Maria Italia , Alberto Schreiber , Chiara Ferracin , Michele Fiorini , Kathy L Newell , Laura Cracco , Holly J Garringer , Maria Paola Cecchini , Magdalini Polymenidou , Alessandro Padovani , Salvatore Monaco , Giuseppe Legname , Bernardino Ghetti , Barbara Borroni , Gianluigi Zanusso

Cryo-EM structures of amyloid-β and tau filaments in Down syndrome.

Nature structural & molecular biology

Avec: Anllely Fernandez , Md Rejaul Hoq , Grace I Hallinan , Daoyi Li , Sakshibeedu R Bharath , Frank S Vago , Xiaoqi Zhang , Kadir A Ozcan , Kathy L Newell , Holly J Garringer , Wen Jiang , Bernardino Ghetti , Ruben Vidal

TAF15 amyloid filaments in frontotemporal lobar degeneration.

Nature

Avec: Stephan Tetter , Diana Arseni , Alexey G Murzin , Yazead Buhidma , Sew Y Peak-Chew , Holly J Garringer , Kathy L Newell , Ruben Vidal , Liana G Apostolova , Tammaryn Lashley , Bernardino Ghetti , Benjamin Ryskeldi-Falcon

Cryo-EM structures of prion protein filaments from Gerstmann-Sträussler-Scheinker disease.

Acta neuropathologica

Avec: Grace I Hallinan , Kadir A Ozcan , Md Rejaul Hoq , Laura Cracco , Frank S Vago , Sakshibeedu R Bharath , Daoyi Li , Max Jacobsen , Emma H Doud , Amber L Mosley , Anllely Fernandez , Holly J Garringer , Wen Jiang , Bernardino Ghetti , Ruben Vidal

Structures of α-synuclein filaments from human brains with Lewy pathology.

Nature

Avec: Yang Yang , Yang Shi , Manuel Schweighauser , Xianjun Zhang , Abhay Kotecha , Alexey G Murzin , Holly J Garringer , Patrick W Cullinane , Yuko Saito , Tatiana Foroud , Thomas T Warner , Kazuko Hasegawa , Ruben Vidal , Shigeo Murayama , Tamas Revesz , Bernardino Ghetti , Masato Hasegawa , Tammaryn Lashley , Sjors H W Scheres , Michel Goedert

Mutation ∆K281 in MAPT causes Pick's disease.

Acta neuropathologica

Avec: Manuel Schweighauser , Holly J Garringer , Therése Klingstedt , K Peter R Nilsson , Masami Masuda-Suzukake , Jill R Murrell , Shannon L Risacher , Ruben Vidal , Sjors H W Scheres , Michel Goedert , Bernardino Ghetti , Kathy L Newell

TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.

Nature

Avec: Diana Arseni , Renren Chen , Alexey G Murzin , Sew Y Peak-Chew , Holly J Garringer , Kathy L Newell , Fuyuki Kametani , Andrew C Robinson , Ruben Vidal , Bernardino Ghetti , Masato Hasegawa , Benjamin Ryskeldi-Falcon

Novel tau filament folds in individuals with

bioRxiv : the preprint server for biology

Avec: Manuel Schweighauser , Yang Shi , Alexey G Murzin , Holly J Garringer , Ruben Vidal , Jill R Murrell , M Elena Erro , Harro Seelaar , Isidro Ferrer , John C van Swieten , Bernardino Ghetti , Sjors H W Scheres , Michel Goedert

Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C.

Nature

Avec: Diana Arseni , Takashi Nonaka , Max H Jacobsen , Alexey G Murzin , Laura Cracco , Sew Y Peak-Chew , Holly J Garringer , Ito Kawakami , Hisaomi Suzuki , Misumoto Onaya , Yuko Saito , Shigeo Murayama , Changiz Geula , Ruben Vidal , Kathy L Newell , Marsel Mesulam , Bernardino Ghetti , Masato Hasegawa , Benjamin Ryskeldi-Falcon

Cryo-EM structures and functional characterization of homo- and heteropolymers of human ferritin variants.

Scientific reports

Avec: Jose Irimia-Dominguez , Chen Sun , Kunpeng Li , Barry B Muhoberac , Grace I Hallinan , Holly J Garringer , Bernardino Ghetti , Wen Jiang , Ruben Vidal

Age-dependent formation of TMEM106B amyloid filaments in human brains.

Nature

Avec: Manuel Schweighauser , Diana Arseni , Mehtap Bacioglu , Melissa Huang , Sofia Lövestam , Yang Shi , Yang Yang , Wenjuan Zhang , Abhay Kotecha , Holly J Garringer , Ruben Vidal , Grace I Hallinan , Kathy L Newell , Airi Tarutani , Shigeo Murayama , Masayuki Miyazaki , Yuko Saito , Mari Yoshida , Kazuko Hasegawa , Tammaryn Lashley , Tamas Revesz , Gabor G Kovacs , John van Swieten , Masaki Takao , Masato Hasegawa , Bernardino Ghetti , Maria Grazia Spillantini , Benjamin Ryskeldi-Falcon , Alexey G Murzin , Michel Goedert , Sjors H W Scheres

Structure of Tau filaments in Prion protein amyloidoses.

Acta neuropathologica

Avec: Grace I Hallinan , Md Rejaul Hoq , Manali Ghosh , Frank S Vago , Anllely Fernandez , Holly J Garringer , Ruben Vidal , Wen Jiang , Bernardino Ghetti

Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.

Acta neuropathologica communications

Avec: Yang Yang , Alexey G Murzin , Sew Peak-Chew , Catarina Franco , Holly J Garringer , Kathy L Newell , Bernardino Ghetti , Michel Goedert , Sjors H W Scheres

Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia.

bioRxiv : the preprint server for biology

Avec: Md Rejaul Hoq , Sakshibeedu R Bharath , Grace I Hallinan , Anllely Fernandez , Frank S Vago , Kadir A Ozcan , Daoyi Li , Holly J Garringer , Ruben Vidal , Bernardino Ghetti , Wen Jiang

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.

Nature

Avec: Benjamin Falcon , Jasenko Zivanov , Wenjuan Zhang , Alexey G Murzin , Holly J Garringer , Ruben Vidal , R Anthony Crowther , Kathy L Newell , Bernardino Ghetti , Michel Goedert , Sjors H W Scheres

Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy.

Acta neuropathologica communications

Avec: Yingjian You , Abigail Perkins , Pablo Cisternas , Braulio Muñoz , Xavier Taylor , Yanwen You , Holly J Garringer , Adrian L Oblak , Brady K Atwood , Ruben Vidal , Cristian A Lasagna-Reeves

Novel tau filament fold in corticobasal degeneration.

Nature

Avec: Wenjuan Zhang , Airi Tarutani , Kathy L Newell , Alexey G Murzin , Tomoyasu Matsubara , Benjamin Falcon , Ruben Vidal , Holly J Garringer , Yang Shi , Takeshi Ikeuchi , Shigeo Murayama , Bernardino Ghetti , Masato Hasegawa , Michel Goedert , Sjors H W Scheres

Distinguishing post-translational modifications in dominantly inherited frontotemporal dementias: FTLD-TDP Type A (GRN) vs Type B (C9orf72).

Neuropathology and applied neurobiology

Avec: Laura Cracco , Emma H Doud , Grace I Hallinan , Holly J Garringer , Max H Jacobsen , Rose M Richardson , Emanuele Buratti , Ruben Vidal , Bernardino Ghetti , Kathy L Newell

New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy.

Acta neuropathologica

Avec: Yang Yang , Holly J Garringer , Yang Shi , Sofia Lövestam , Sew Peak-Chew , Xianjun Zhang , Abhay Kotecha , Mehtap Bacioglu , Atsuo Koto , Masaki Takao , Maria Grazia Spillantini , Bernardino Ghetti , Ruben Vidal , Alexey G Murzin , Sjors H W Scheres , Michel Goedert

Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C.

bioRxiv : the preprint server for biology

Réseau de co-auteurs

Bernardino Ghetti 23 collaborations

Ruben Vidal 22 collaborations

Alexey G Murzin 14 collaborations

Kathy L Newell 14 collaborations

Sjors H W Scheres 11 collaborations

Michel Goedert 11 collaborations

Grace I Hallinan 9 collaborations

Yang Shi 7 collaborations

Masato Hasegawa 7 collaborations

Yang Yang 6 collaborations

Diana Arseni 6 collaborations

Benjamin Ryskeldi-Falcon 6 collaborations

Wen Jiang 6 collaborations

Shigeo Murayama 6 collaborations

Wenjuan Zhang 5 collaborations

Manuel Schweighauser 5 collaborations

Abhay Kotecha 5 collaborations

Sew Y Peak-Chew 5 collaborations

Md Rejaul Hoq 5 collaborations

Anllely Fernandez 5 collaborations

Frank S Vago 5 collaborations

Yuko Saito 5 collaborations

Laura Cracco 5 collaborations

Benjamin Falcon 4 collaborations

Sakshibeedu R Bharath 4 collaborations

Daoyi Li 4 collaborations

Kadir A Ozcan 4 collaborations

Tammaryn Lashley 4 collaborations

Sofia Lövestam 3 collaborations

Gabor G Kovacs 3 collaborations

Airi Tarutani 3 collaborations

Tamas Revesz 3 collaborations

Max H Jacobsen 3 collaborations

Melissa Huang 2 collaborations

Fuyuki Kametani 2 collaborations

Mari Yoshida 2 collaborations

Takeshi Ikeuchi 2 collaborations

Andrew C Robinson 2 collaborations

Emanuele Buratti 2 collaborations

Emma H Doud 2 collaborations

Xianjun Zhang 2 collaborations

Kazuko Hasegawa 2 collaborations

Jill R Murrell 2 collaborations

Takashi Nonaka 2 collaborations

Ito Kawakami 2 collaborations

Hisaomi Suzuki 2 collaborations

Misumoto Onaya 2 collaborations

Changiz Geula 2 collaborations

Marsel Mesulam 2 collaborations

Mehtap Bacioglu 2 collaborations

Masaki Takao 2 collaborations

Maria Grazia Spillantini 2 collaborations

Sew Peak-Chew 2 collaborations

Alexander Epstein 1 collaboration

Jonathan Machin 1 collaboration

Paul Tempest 1 collaboration

Naruhiko Sahara 1 collaboration

Makoto Higuchi 1 collaboration

Ming-Kuei Jang 1 collaboration

Jennifer Macdonald 1 collaboration

Isabelle Lavenir 1 collaboration

Ellen Gelpi 1 collaboration

Mike van Beers 1 collaboration

Hidetomo Tanaka 1 collaboration

Akiyoshi Kakita 1 collaboration

David M A Mann 1 collaboration

Joyce W Tam 1 collaboration

Kiran Khurshid 1 collaboration

Briana Sprague 1 collaboration

Daniel O Clark 1 collaboration

Huiping Xu 1 collaboration

Lyndsi R Moser 1 collaboration

Douglas K Miller 1 collaboration

Robert Considine 1 collaboration

Christopher M Callahan 1 collaboration

Daniel Rexroth 1 collaboration

Frederick W Unverzagt 1 collaboration

Elena Fontana 1 collaboration

Matilde Bongianni 1 collaboration

Alberto Benussi 1 collaboration

Erika Bronzato 1 collaboration

Carlo Scialo 1 collaboration

Luca Sacchetto 1 collaboration

Annachiara Cagnin 1 collaboration

Santina Castriciano 1 collaboration

Fabrizio Gardoni 1 collaboration

Maria Italia 1 collaboration

Alberto Schreiber 1 collaboration

Chiara Ferracin 1 collaboration

Michele Fiorini 1 collaboration

Maria Paola Cecchini 1 collaboration

Magdalini Polymenidou 1 collaboration

Alessandro Padovani 1 collaboration

Salvatore Monaco 1 collaboration

Giuseppe Legname 1 collaboration

Barbara Borroni 1 collaboration

Gianluigi Zanusso 1 collaboration

Xiaoqi Zhang 1 collaboration

Stephan Tetter 1 collaboration

Yazead Buhidma 1 collaboration

Liana G Apostolova 1 collaboration

Max Jacobsen 1 collaboration

Amber L Mosley 1 collaboration

Patrick W Cullinane 1 collaboration

Tatiana Foroud 1 collaboration

Thomas T Warner 1 collaboration

Therése Klingstedt 1 collaboration

K Peter R Nilsson 1 collaboration

Masami Masuda-Suzukake 1 collaboration

Shannon L Risacher 1 collaboration

Renren Chen 1 collaboration

M Elena Erro 1 collaboration

Harro Seelaar 1 collaboration

Isidro Ferrer 1 collaboration

John C van Swieten 1 collaboration

Jose Irimia-Dominguez 1 collaboration

Chen Sun 1 collaboration

Kunpeng Li 1 collaboration

Barry B Muhoberac 1 collaboration

Masayuki Miyazaki 1 collaboration

John van Swieten 1 collaboration

Manali Ghosh 1 collaboration

Catarina Franco 1 collaboration

Jasenko Zivanov 1 collaboration

R Anthony Crowther 1 collaboration

Yingjian You 1 collaboration

Abigail Perkins 1 collaboration

Pablo Cisternas 1 collaboration

Braulio Muñoz 1 collaboration

Xavier Taylor 1 collaboration

Yanwen You 1 collaboration

Adrian L Oblak 1 collaboration

Brady K Atwood 1 collaboration

Cristian A Lasagna-Reeves 1 collaboration

Tomoyasu Matsubara 1 collaboration

Rose M Richardson 1 collaboration

Atsuo Koto 1 collaboration