Hideki Suganami

Affiliations

Clinical Data Science Department, Pharmaceutical Division Kowa Company, Ltd., Tokyo, Japan.

Publications (30)

Evaluation of Data Errors and Monitoring Activities in a Trial in Japan Using a Risk-Based Approach Including Central Monitoring and Site Risk Assessment.

Therapeutic innovation & regulatory science

Avec: Hidenobu Kondo , Tomoaki Kamiyoshihara , Kenji Fujisawa , Toshiaki Nojima , Ryohei Tanigawa , Hisataka Fujiwara , Hideki Suganami , Yukikazu Hayashi , Takuhiro Yamaguchi

Dipeptidyl peptidase-4 inhibitor, anagliptin, alters hepatic insulin clearance in relation to the glycemic status in Japanese individuals with type 2 diabetes.

Journal of diabetes investigation

Avec: Takahiro Abe , Yasuhiro Matsubayashi , Sayaka Muragishi , Akihiro Yoshida , Hideki Suganami , Kenichi Furusawa , Kazuya Fujihara , Shiro Tanaka , Kohei Kaku , Hirohito Sone

Efficacy and Safety of K-877 (Pemafibrate), a Selective PPARα Modulator, in European Patients on Statin Therapy.

Diabetes care

Avec: Henry N Ginsberg , Neil J Hounslow , Yusuke Senko , Hideki Suganami , Pawel Bogdanski , Richard Ceska , Akos Kalina , Roman A Libis , Tatiana V Supryadkina , G Kees Hovingh

Renal effects of a sodium-glucose cotransporter 2 inhibitor, tofogliflozin, in relation to sodium intake and glycaemic status.

Diabetes, obesity & metabolism

Avec: Kiyohide Nunoi , Yuichi Sato , Kohei Kaku , Akihiro Yoshida , Hideki Suganami

Randomised clinical trial: Pemafibrate, a novel selective peroxisome proliferator-activated receptor α modulator (SPPARMα), versus placebo in patients with non-alcoholic fatty liver disease.

Alimentary pharmacology & therapeutics

Avec: Atsushi Nakajima , Yuichiro Eguchi , Masato Yoneda , Kento Imajo , Nobuharu Tamaki , Hideki Suganami , Toshiaki Nojima , Ryohei Tanigawa , Masakazu Iizuka , Yuki Iida , Rohit Loomba

Long-term Efficacy and Safety of K-924 Pitavastatin/Ezetimibe Fixed-dose Combination in Patients with Hypercholesterolemia: A Phase III, Multi-center, Open-label Trial.

Journal of atherosclerosis and thrombosis

Avec: Junya Ako , Koutaro Yokote , Kenichi Tsujita , Ryohei Tanigawa , Ryo Kamei , Hideki Suganami , Auteur inconnu

Reductions in liver enzymes are associated with anti-hyperglycaemic and anti-obesity effects of tofogliflozin in people with type 2 diabetes: Post-hoc analyses.

Endocrinology, diabetes & metabolism

Avec: Toshinari Takamura , Kohei Kaku , Akihiro Yoshida , Hiromi Kusakabe , Hiroyuki Nakamura , Hideki Suganami

Crossover Randomized Study of Pharmacologic Effects of Ripasudil-Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine.

Advances in therapy

Avec: Hidenobu Tanihara , Tetsuya Yamamoto , Makoto Aihara , Noriko Koizumi , Hiroomi Minami , Satoshi Kojima , Tomoyuki Isobe , Mizuho Kanazawa , Hideki Suganami , Auteur inconnu

Drug-drug interactions between pemafibrate and statins on pharmacokinetics in healthy male volunteers: Open-label, randomized, 6-sequence, 3-period crossover studies.

Clinical and translational science

Avec: Tomohiro Kamimura , Neil Hounslow , Hideki Suganami , Ryohei Tanigawa

Clinical Pharmacology of Pemafibrate Extended-release Formulation in Patients with Hypertriglyceridemia-A Phase 2, Multicenter, Active-controlled, Randomized, Single-blind, Crossover study.

Journal of atherosclerosis and thrombosis

Avec: Shizuya Yamashita , Eiichi Araki , Hidenori Arai , Koutaro Yokote , Ryohei Tanigawa , Ayumi Saito , Hideki Suganami , Sara Minamikawa , Shun Ishibashi

Association of estimated plasma volume and weight loss after long-term administration and subsequent discontinuation of the sodium-glucose cotransporter-2 inhibitor tofogliflozin.

Diabetes, obesity & metabolism

Avec: Yasuhiro Matsubayashi , Akihiro Yoshida , Hideki Suganami , Momoko Oe , Takaaki Sato , Yuta Yaguchi , Kazuya Fujihara , Takaho Yamada , Shiro Tanaka , Kohei Kaku , Hirohito Sone

Basal insulin secretion capacity predicts the initial response and maximum levels of beta-hydroxybutyrate during therapy with the sodium-glucose co-transporter-2 inhibitor tofogliflozin, in relation to weight loss.

Diabetes, obesity & metabolism

Avec: Yuichi Sato , Kiyohide Nunoi , Kohei Kaku , Akihiro Yoshida , Hideki Suganami

Long-term safety and efficacy of the sodium-glucose cotransporter 2 inhibitor, tofogliflozin, added on glucagon-like peptide-1 receptor agonist in Japanese patients with type 2 diabetes mellitus: A 52-week open-label, multicenter, post-marketing clinical study.

Journal of diabetes investigation

Avec: Yasuo Terauchi , Hisataka Fujiwara , Yuji Kurihara , Hideki Suganami , Masahiro Tamura , Masayuki Senda , Ryoji Gunji , Kohei Kaku

Association of increased hepatic insulin clearance and change in serum triglycerides or β-hydroxybutyrate concentration via the sodium/glucose-cotransporter 2 inhibitor tofogliflozin.

Diabetes, obesity & metabolism

Avec: Yasuhiro Matsubayashi , Akihiro Yoshida , Hideki Suganami , Taeko Osawa , Kazuo Furukawa , Hiroshi Suzuki , Kazuya Fujihara , Shiro Tanaka , Kohei Kaku , Hirohito Sone

Influence of an SGLT2 inhibitor, tofogliflozin, on the resting heart rate in relation to adipose tissue insulin resistance.

Diabetic medicine : a journal of the British Diabetic Association

Avec: T Nojima , Y Matsubayashi , A Yoshida , H Suganami , T Abe , M Ishizawa , K Fujihara , S Tanaka , K Kaku , H Sone

Multiplicity Adjustment and Sample Size Calculation in Clinical Trials with Multiple Endpoints: An Industry Survey of Current Practices in Japan.

Therapeutic innovation & regulatory science

Avec: Kentaro Sakamaki , Yusuke Morita , Katsuhiro Iba , Toshifumi Kamiura , Seitaro Yoshida , Naoyuki Ogawa , Hideki Suganami , Satoru Tsuchiya , Satoru Fukimbara

Efficacy and Safety of Pitavastatin/Ezetimibe Fixed-Dose Combination vs. Pitavastatin: Phase III, Double-Blind, Randomized Controlled Trial.

Journal of atherosclerosis and thrombosis

Avec: Kenichi Tsujita , Koutaro Yokote , Junya Ako , Ryohei Tanigawa , Sachiko Tajima , Hideki Suganami

Efficacy and safety of ivermectin in patients with mild COVID-19 in Japan and Thailand.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Avec: Hiroshige Mikamo , Satoshi Takahashi , Yuka Yamagishi , Akihiro Hirakawa , Toshiyuki Harada , Hirotaka Nagashima , Chiaki Noguchi , Kentaro Masuko , Hiromitsu Maekawa , Tatsuhiko Kashii , Hiroyuki Ohbayashi , Shinichiro Hosokawa , Katsuyuki Maejima , Masaya Yamato , Weerawat Manosuthi , Supachai Paiboonpol , Hideki Suganami , Ryohei Tanigawa , Hitoshi Kawamura , Auteur inconnu

Challenges on Multiple Endpoints in Clinical Trials: An Industry Survey in Japan.

Therapeutic innovation & regulatory science

Avec: Kentaro Sakamaki , Seitaro Yoshida , Yusuke Morita , Toshifumi Kamiura , Katsuhiro Iba , Naoyuki Ogawa , Hideki Suganami , Satoru Tsuchiya , Satoru Fukimbara

Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment.

International journal of molecular sciences

Avec: Koutaro Yokote , Shizuya Yamashita , Hidenori Arai , Eiichi Araki , Hideki Suganami , Shun Ishibashi , On Behalf Of The K-Study Group

Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52-week data from the PROVIDE study.

Diabetes, obesity & metabolism

Avec: Eiichi Araki , Shizuya Yamashita , Hidenori Arai , Koutaro Yokote , Jo Satoh , Toyoshi Inoguchi , Jiro Nakamura , Hiroshi Maegawa , Narihito Yoshioka , Yukio Tanizawa , Hirotaka Watada , Hideki Suganami , Shun Ishibashi

Attenuation of Weight Loss Through Improved Antilipolytic Effect in Adipose Tissue Via the SGLT2 Inhibitor Tofogliflozin.

The Journal of clinical endocrinology and metabolism

Avec: Akihiro Yoshida , Yasuhiro Matsubayashi , Toshiaki Nojima , Hideki Suganami , Takahiro Abe , Masahiro Ishizawa , Kazuya Fujihara , Shiro Tanaka , Kohei Kaku , Hirohito Sone

Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα): Pooled Analysis of Phase 2 and 3 Studies in Dyslipidemic Patients with or without Statin Combination.

International journal of molecular sciences

Avec: Shizuya Yamashita , Hidenori Arai , Koutaro Yokote , Eiichi Araki , Mitsunori Matsushita , Toshiaki Nojima , Hideki Suganami , Shun Ishibashi

Long-term intraocular pressure-lowering efficacy and safety of ripasudil-brimonidine fixed-dose combination for glaucoma and ocular hypertension: a multicentre, open-label, phase 3 study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Avec: Hidenobu Tanihara , Tetsuya Yamamoto , Makoto Aihara , Noriko Koizumi , Atsuki Fukushima , Koji Kawakita , Satoshi Kojima , Toka Nakamura , Hideki Suganami , Auteur inconnu

Efficacy and Safety of Pemafibrate Extended-Release Tablet: a Phase 3, Multicenter, Randomized, Double-Blind, Active-Controlled, Parallel-Group Comparison Trial.

Journal of atherosclerosis and thrombosis

Avec: Hidenori Arai , Shizuya Yamashita , Eiichi Araki , Koutaro Yokote , Ryohei Tanigawa , Ayumi Saito , Sayumi Yamasaki , Hideki Suganami , Shun Ishibashi

Pharmacokinetics and Safety of Pemafibrate in Patients with both Dyslipidemia and Severe Renal Impairment: A Phase 4 Study.

Journal of atherosclerosis and thrombosis

Avec: Shun Ishibashi , Hidenori Arai , Koutaro Yokote , Eiichi Araki , Mao Watanabe , Michiko Nakanishi , Yuichi Makinose , Hideki Suganami , Yuji Kurihara , Shizuya Yamashita

Restricted mean survival time as a summary measure of time-to-event outcome.

Pharmaceutical statistics

Avec: Takahiro Hasegawa , Saori Misawa , Shintaro Nakagawa , Shinichi Tanaka , Takanori Tanase , Hiroyuki Ugai , Akira Wakana , Yasuhide Yodo , Satoru Tsuchiya , Hideki Suganami , Auteur inconnu

Challenges on Multiple Endpoints in Clinical Trials: An Industry Survey in Japan.

Therapeutic innovation & regulatory science

Avec: Kentaro Sakamaki , Seitaro Yoshida , Yusuke Morita , Toshifumi Kamiura , Katsuhiro Iba , Naoyuki Ogawa , Hideki Suganami , Satoru Tsuchiya , Satoru Fukimbara

Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double-blind placebo-controlled clinical trials.

Cardiovascular diabetology

Avec: Koutaro Yokote , Shizuya Yamashita , Hidenori Arai , Eiichi Araki , Mitsunori Matsushita , Toshiaki Nojima , Hideki Suganami , Shun Ishibashi

Ripasudil-Brimonidine Fixed-Dose Combination vs Ripasudil or Brimonidine: Two Phase 3 Randomized Clinical Trials.

American journal of ophthalmology

Avec: Hidenobu Tanihara , Tetsuya Yamamoto , Makoto Aihara , Koji Kawakita , Satoshi Kojima , Mizuho Kanazawa , Toshiaki Nojima , Hideki Suganami , Auteur inconnu

Réseau de co-auteurs

Koutaro Yokote 9 collaborations

Ryohei Tanigawa 8 collaborations

Kohei Kaku 8 collaborations

Akihiro Yoshida 7 collaborations

Shizuya Yamashita 7 collaborations

Eiichi Araki 7 collaborations

Hidenori Arai 7 collaborations

Shun Ishibashi 7 collaborations

Toshiaki Nojima 6 collaborations

None None 6 collaborations

Yasuhiro Matsubayashi 4 collaborations

Kazuya Fujihara 4 collaborations

Shiro Tanaka 4 collaborations

Hirohito Sone 4 collaborations

Satoru Tsuchiya 4 collaborations

Hidenobu Tanihara 3 collaborations

Tetsuya Yamamoto 3 collaborations

Makoto Aihara 3 collaborations

Satoshi Kojima 3 collaborations

Kentaro Sakamaki 3 collaborations

Yusuke Morita 3 collaborations

Katsuhiro Iba 3 collaborations

Toshifumi Kamiura 3 collaborations

Seitaro Yoshida 3 collaborations

Naoyuki Ogawa 3 collaborations

Satoru Fukimbara 3 collaborations

Hisataka Fujiwara 2 collaborations

Takahiro Abe 2 collaborations

Kiyohide Nunoi 2 collaborations

Yuichi Sato 2 collaborations

Junya Ako 2 collaborations

Kenichi Tsujita 2 collaborations

Noriko Koizumi 2 collaborations

Mizuho Kanazawa 2 collaborations

Ayumi Saito 2 collaborations

Yuji Kurihara 2 collaborations

Mitsunori Matsushita 2 collaborations

Koji Kawakita 2 collaborations

Hidenobu Kondo 1 collaboration

Tomoaki Kamiyoshihara 1 collaboration

Kenji Fujisawa 1 collaboration

Yukikazu Hayashi 1 collaboration

Takuhiro Yamaguchi 1 collaboration

Sayaka Muragishi 1 collaboration

Kenichi Furusawa 1 collaboration

Henry N Ginsberg 1 collaboration

Neil J Hounslow 1 collaboration

Yusuke Senko 1 collaboration

Pawel Bogdanski 1 collaboration

Richard Ceska 1 collaboration

Akos Kalina 1 collaboration

Roman A Libis 1 collaboration

Tatiana V Supryadkina 1 collaboration

G Kees Hovingh 1 collaboration

Atsushi Nakajima 1 collaboration

Yuichiro Eguchi 1 collaboration

Masato Yoneda 1 collaboration

Kento Imajo 1 collaboration

Nobuharu Tamaki 1 collaboration

Masakazu Iizuka 1 collaboration

Yuki Iida 1 collaboration

Rohit Loomba 1 collaboration

Ryo Kamei 1 collaboration

Toshinari Takamura 1 collaboration

Hiromi Kusakabe 1 collaboration

Hiroyuki Nakamura 1 collaboration

Hiroomi Minami 1 collaboration

Tomoyuki Isobe 1 collaboration

Tomohiro Kamimura 1 collaboration

Neil Hounslow 1 collaboration

Sara Minamikawa 1 collaboration

Momoko Oe 1 collaboration

Takaaki Sato 1 collaboration

Yuta Yaguchi 1 collaboration

Takaho Yamada 1 collaboration

Yasuo Terauchi 1 collaboration

Masahiro Tamura 1 collaboration

Masayuki Senda 1 collaboration

Ryoji Gunji 1 collaboration

Taeko Osawa 1 collaboration

Kazuo Furukawa 1 collaboration

Hiroshi Suzuki 1 collaboration

T Nojima 1 collaboration

Y Matsubayashi 1 collaboration

A Yoshida 1 collaboration

H Suganami 1 collaboration

T Abe 1 collaboration

M Ishizawa 1 collaboration

K Fujihara 1 collaboration

S Tanaka 1 collaboration

K Kaku 1 collaboration

H Sone 1 collaboration

Sachiko Tajima 1 collaboration

Hiroshige Mikamo 1 collaboration

Satoshi Takahashi 1 collaboration

Yuka Yamagishi 1 collaboration

Akihiro Hirakawa 1 collaboration

Toshiyuki Harada 1 collaboration

Hirotaka Nagashima 1 collaboration

Chiaki Noguchi 1 collaboration

Kentaro Masuko 1 collaboration

Hiromitsu Maekawa 1 collaboration

Tatsuhiko Kashii 1 collaboration

Hiroyuki Ohbayashi 1 collaboration

Shinichiro Hosokawa 1 collaboration

Katsuyuki Maejima 1 collaboration

Masaya Yamato 1 collaboration

Weerawat Manosuthi 1 collaboration

Supachai Paiboonpol 1 collaboration

Hitoshi Kawamura 1 collaboration

On Behalf Of The K-Study Group 1 collaboration

Jo Satoh 1 collaboration

Toyoshi Inoguchi 1 collaboration

Jiro Nakamura 1 collaboration

Hiroshi Maegawa 1 collaboration

Narihito Yoshioka 1 collaboration

Yukio Tanizawa 1 collaboration

Hirotaka Watada 1 collaboration

Masahiro Ishizawa 1 collaboration

Atsuki Fukushima 1 collaboration

Toka Nakamura 1 collaboration

Sayumi Yamasaki 1 collaboration

Mao Watanabe 1 collaboration

Michiko Nakanishi 1 collaboration

Yuichi Makinose 1 collaboration

Takahiro Hasegawa 1 collaboration

Saori Misawa 1 collaboration

Shintaro Nakagawa 1 collaboration

Shinichi Tanaka 1 collaboration

Takanori Tanase 1 collaboration

Hiroyuki Ugai 1 collaboration

Akira Wakana 1 collaboration

Yasuhide Yodo 1 collaboration