Heinner Guio

Affiliations

Laboratorio de Biotecnología y Biología Molecular, Instituto Nacional de Salud, Lima 9, Peru; edutars@gmail.com heinnerguio@gmail.com.
Carrera de Medicina Humana, Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, 150142, Peru.
Facultad de Ciencias de la Salud, Universidad de Huánuco, Huánuco, 10001, Peru.

Publications (21)

The genetic structure and adaptation of Andean highlanders and Amazonians are influenced by the interplay between geography and culture.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Víctor Borda , Isabela Alvim , Marla Mendes , Carolina Silva-Carvalho , Giordano B Soares-Souza , Thiago P Leal , Vinicius Furlan , Marilia O Scliar , Roxana Zamudio , Camila Zolini , Gilderlanio S Araújo , Marcelo R Luizon , Carlos Padilla , Omar Cáceres , Kelly Levano , César Sánchez , Omar Trujillo , Pedro O Flores-Villanueva , Michael Dean , Silvia Fuselli , Moara Machado , Pedro E Romero , Francesca Tassi , Meredith Yeager , Timothy D O'Connor , Robert H Gilman , Eduardo Tarazona-Santos , Heinner Guio

CXCR4 Knockdown Via CRISPR/CAS9 in a Tumor-Associated Macrophage Model Decreases Human Breast Cancer Cell Migration.

Cureus

Avec: Luis Jaramillo-Valverde , Kelly S Levano , Silvia Capristano , David D Tarazona , Alberto Cisneros , Velia M Yufra-Picardo , Julio Valdivia-Silva , Heinner Guio

The need to diversify genomic studies: Insights from Andean highlanders and Amazonians.

Cell

Avec: Isabela Alvim , Carolina Silva-Carvalho , Marla Mendes de Aquino , Victor Borda , Cesar Sanchez , Carlos Padilla , Omar Cáceres , Isabela Rezende-Diniz , Julia Saraiva-Duarte , Lucas Faria-Costa , Meddly L Santolalla , Fernanda Rodrigues-Soares , Camila Zolini , Adrián Llerena , Timothy D O'Connor , Robert H Gilman , Heinner Guio , Eduardo Tarazona-Santos

A positively selected FBN1 missense variant reduces height in Peruvian individuals.

Nature

Avec: Samira Asgari , Yang Luo , Ali Akbari , Gillian M Belbin , Xinyi Li , Daniel N Harris , Martin Selig , Eric Bartell , Roger Calderon , Kamil Slowikowski , Carmen Contreras , Rosa Yataco , Jerome T Galea , Judith Jimenez , Julia M Coit , Chandel Farroñay , Rosalynn M Nazarian , Timothy D O'Connor , Harry C Dietz , Joel N Hirschhorn , Heinner Guio , Leonid Lecca , Eimear E Kenny , Esther E Freeman , Megan B Murray , Soumya Raychaudhuri

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients.

Molecular genetics & genomic medicine

Avec: Kelly S Levano , Luis Jaramillo-Valverde , David D Tarazona , Cesar Sanchez , Silvia Capristano , Tania Vásquez-Loarte , Lely Solari , Alberto Mendoza-Ticona , Alonso Soto , Christian Rojas , Roberto Zegarra-Chapoñan , Heinner Guio

Tracing the Distribution of European Lactase Persistence Genotypes Along the Americas.

Frontiers in genetics

Avec: Ana Cecília Guimarães Alves , Natalie Mary Sukow , Gabriel Adelman Cipolla , Marla Mendes , Thiago P Leal , Maria Luiza Petzl-Erler , Ricardo Lehtonen Rodrigues Souza , Ilíada Rainha de Souza , Cesar Sanchez , Meddly Santolalla , Douglas Loesch , Michael Dean , Moara Machado , Jee-Young Moon , Robert Kaplan , Kari E North , Scott Weiss , Mauricio L Barreto , M Fernanda Lima-Costa , Heinner Guio , Omar Cáceres , Carlos Padilla , Eduardo Tarazona-Santos , Ignacio F Mata , Elena Dieguez , Víctor Raggio , Andres Lescano , Vitor Tumas , Vanderci Borges , Henrique B Ferraz , Carlos R Rieder , Artur Schumacher-Schuh , Bruno L Santos-Lobato , Pedro Chana-Cuevas , William Fernandez , Gonzalo Arboleda , Humberto Arboleda , Carlos E Arboleda-Bustos , Timothy D O'Connor , Marcia Holsbach Beltrame , Victor Borda

Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans.

Genetics and molecular biology

Avec: Fernanda S G Kehdy , Murilo Pita-Oliveira , Mariana M Scudeler , Sabrina Torres-Loureiro , Camila Zolini , Rennan Moreira , Lucas A Michelin , Isabela Alvim , Carolina Silva-Carvalho , Vinicius C Furlan , Marla M Aquino , Meddly L Santolalla , Victor Borda , Giordano B Soares-Souza , Luis Jaramillo-Valverde , Andres Vasquez-Dominguez , Cesar Sanchez Neira , Renato S Aguiar , Ricardo A Verdugo , Timothy D O Connor , Heinner Guio , Eduardo Tarazona-Santos , Thiago P Leal , Fernanda Rodrigues-Soares

NAT2 and CYP2E1 polymorphisms and antituberculosis drug-induced hepatotoxicity in Peruvian patients.

Molecular genetics & genomic medicine

Avec: Luis Jaramillo-Valverde , Kelly S Levano , David D Tarazona , Silvia Capristano , Roberto Zegarra-Chapoñan , Cesar Sanchez , Velia M Yufra-Picardo , Eduardo Tarazona-Santos , Cesar Ugarte-Gil , Heinner Guio

Comparative Profiling of Circulating Exosomal Small RNAs Derived From Peruvian Patients With Tuberculosis and Pulmonary Adenocarcinoma.

Frontiers in cellular and infection microbiology

Avec: Heinner Guio , Victor Aliaga-Tobar , Marco Galarza , Oscar Pellon-Cardenas , Silvia Capristano , Henry L Gomez , Mivael Olivera , Cesar Sanchez , Vinicius Maracaja-Coutinho

Population genetics of PDE4B (phosphodiesterase-4B) in neglected Native Americans: Implications for cancer pharmacogenetics.

Clinical and translational science

Avec: Rennan Garcias Moreira , Julia Maria Saraiva-Duarte , Alexandre Costa Pereira , Martha Sosa-Macias , Carlos Galaviz-Hernandez , Meddly Lesley Santolalla , Wagner C S Magalhães , Camila Zolini , Thiago Peixoto Leal , Zsolt Balázs , Adrián Llerena , Robert H Gilman , José Geraldo Mill , Victor Borda , Heinner Guio , Timothy D O'Connor , Eduardo Tarazona-Santos , Fernanda Rodrigues-Soares

Pharmacogenetic variability of tuberculosis biomarkers in native and mestizo Peruvian populations.

Pharmacology research & perspectives

Avec: Luis Jaramillo-Valverde , Kelly S Levano , David D Tarazona , Silvia Capristano , Cesar Sanchez , Julio A Poterico , Eduardo Tarazona-Santos , Heinner Guio

A mobile lab for ancient DNA extraction in Perug.

Bioinformation

Avec: Luis Jaramillo-Valverde , Andrés Vásquez-Domínguez , Kelly S Levano , Rony Castrejon-Cabanillas , Pedro Novoa-Bellota , Marco Machacuay-Romero , Ruth Garcia-de-la-Guarda , Raul J Cano , Ruth Shady Solis , Heinner Guio

Differential expression of circulating micro-RNAs in patients with active and latent tuberculosis.

Revista peruana de medicina experimental y salud publica

Avec: José Yareta , Marco Galarza , Silvia Capristano , Oscar Pellón , César Sánchez , Jorge Ballon , Heinner Guio

Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.

International journal of obesity (2005)

Avec: Marilia O Scliar , Hanaisa P Sant'Anna , Meddly L Santolalla , Thiago P Leal , Nathalia M Araújo , Isabela Alvim , Victor Borda , Wagner C S Magalhães , Mateus H Gouveia , Ricardo Lyra , Moara Machado , Lucas Michelin , Maíra R Rodrigues , Gilderlanio S Araújo , Fernanda S G Kehdy , Camila Zolini , Sérgio V Peixoto , Marcelo R Luizon , Francisco Lobo , Michel S Naslavsky , Guilherme L Yamamoto , Yeda A O Duarte , Matthew E B Hansen , Shane A Norris , Robert H Gilman , Heinner Guio , Ann W Hsing , Sam M Mbulaiteye , James Mensah , Julie Dutil , Meredith Yeager , Edward Yeboah , Sarah A Tishkoff , Ananyo Choudhury , Michele Ramsay , Maria Rita Passos-Bueno , Mayana Zatz , Timothy D O Connor , Alexandre C Pereira , Mauricio L Barreto , Maria Fernanda Lima-Costa , Bernardo L Horta , Eduardo Tarazona-Santos

Biased pathogenic assertions of loss of function variants challenge molecular diagnosis of admixed individuals.

American journal of medical genetics. Part C, Seminars in medical genetics

Avec: Michel S Naslavsky , Marília O Scliar , Kelly Nunes , Jaqueline Y T Wang , Guilherme L Yamamoto , Heinner Guio , Eduardo Tarazona-Santos , Yeda A O Duarte , Maria Rita Passos-Bueno , Diogo Meyer , Mayana Zatz

Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Brazil.

Nature communications

Avec: Michel S Naslavsky , Marilia O Scliar , Guilherme L Yamamoto , Jaqueline Yu Ting Wang , Stepanka Zverinova , Tatiana Karp , Kelly Nunes , José Ricardo Magliocco Ceroni , Diego Lima de Carvalho , Carlos Eduardo da Silva Simões , Daniel Bozoklian , Ricardo Nonaka , Nayane Dos Santos Brito Silva , Andreia da Silva Souza , Heloísa de Souza Andrade , Marília Rodrigues Silva Passos , Camila Ferreira Bannwart Castro , Celso T Mendes-Junior , Rafael L V Mercuri , Thiago L A Miller , Jose Leonel Buzzo , Fernanda O Rego , Nathalia M Araújo , Wagner C S Magalhães , Regina Célia Mingroni-Netto , Victor Borda , Heinner Guio , Carlos P Rojas , Cesar Sanchez , Omar Caceres , Michael Dean , Mauricio L Barreto , Maria Fernanda Lima-Costa , Bernardo L Horta , Eduardo Tarazona-Santos , Diogo Meyer , Pedro A F Galante , Victor Guryev , Erick C Castelli , Yeda A O Duarte , Maria Rita Passos-Bueno , Mayana Zatz

Antigen-Induced IL-1RA Production Discriminates Active and Latent Tuberculosis Infection.

Microorganisms

Avec: Cesar Sanchez , Luis Jaramillo-Valverde , Silvia Capristano , Gilmer Solis , Alonso Soto , Julio Valdivia-Silva , Julio A Poterico , Heinner Guio

Origins, Admixture Dynamics, and Homogenization of the African Gene Pool in the Americas.

Molecular biology and evolution

Avec: Mateus H Gouveia , Victor Borda , Thiago P Leal , Rennan G Moreira , Andrew W Bergen , Fernanda S G Kehdy , Isabela Alvim , Marla M Aquino , Gilderlanio S Araujo , Nathalia M Araujo , Vinicius Furlan , Raquel Liboredo , Moara Machado , Wagner C S Magalhaes , Lucas A Michelin , Maíra R Rodrigues , Fernanda Rodrigues-Soares , Hanaisa P Sant Anna , Meddly L Santolalla , Marília O Scliar , Giordano Soares-Souza , Roxana Zamudio , Camila Zolini , Maria Catira Bortolini , Michael Dean , Robert H Gilman , Heinner Guio , Jorge Rocha , Alexandre C Pereira , Mauricio L Barreto , Bernardo L Horta , Maria F Lima-Costa , Sam M Mbulaiteye , Stephen J Chanock , Sarah A Tishkoff , Meredith Yeager , Eduardo Tarazona-Santos

Guillain-Barre syndrome outbreak in Peru: Association with polymorphisms in IL-17, ICAM1, and CD1.

Molecular genetics & genomic medicine

Avec: Luis Jaramillo-Valverde , Kelly S Levano , Isolina Villanueva , Meylin Hidalgo , Marco Cornejo , Pilar Mazzetti , Mario Cornejo-Olivas , Cesar Sanchez , Julio A Poterico , Julio Valdivia-Silva , Heinner Guio

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World.

Genome biology and evolution

Avec: Daniel N Harris , Ingo Ruczinski , Lisa R Yanek , Lewis C Becker , Diane M Becker , Heinner Guio , Tao Cui , Floyd H Chilton , Rasika A Mathias , Timothy D O'Connor

International journal of molecular sciences

Avec: Luis Jaramillo-Valverde , Kelly S Levano , David D Tarazona , Andres Vasquez-Dominguez , Anel Toledo-Nauto , Silvia Capristano , Cesar Sanchez , Eduardo Tarazona-Santos , Cesar Ugarte-Gil , Heinner Guio

Réseau de co-auteurs

Eduardo Tarazona-Santos 12 collaborations

Cesar Sanchez 10 collaborations

Luis Jaramillo-Valverde 9 collaborations

Silvia Capristano 8 collaborations

Kelly S Levano 7 collaborations

Victor Borda 7 collaborations

Camila Zolini 6 collaborations

Timothy D O'Connor 6 collaborations

Isabela Alvim 5 collaborations

Thiago P Leal 5 collaborations

Robert H Gilman 5 collaborations

David D Tarazona 5 collaborations

Michael Dean 4 collaborations

Moara Machado 4 collaborations

Meddly L Santolalla 4 collaborations

Fernanda Rodrigues-Soares 4 collaborations

Mauricio L Barreto 4 collaborations

Carolina Silva-Carvalho 3 collaborations

Marilia O Scliar 3 collaborations

Carlos Padilla 3 collaborations

Omar Cáceres 3 collaborations

Meredith Yeager 3 collaborations

Julio Valdivia-Silva 3 collaborations

Fernanda S G Kehdy 3 collaborations

Wagner C S Magalhães 3 collaborations

Julio A Poterico 3 collaborations

Michel S Naslavsky 3 collaborations

Guilherme L Yamamoto 3 collaborations

Yeda A O Duarte 3 collaborations

Maria Rita Passos-Bueno 3 collaborations

Mayana Zatz 3 collaborations

Bernardo L Horta 3 collaborations

Marla Mendes 2 collaborations

Giordano B Soares-Souza 2 collaborations

Vinicius Furlan 2 collaborations

Roxana Zamudio 2 collaborations

Gilderlanio S Araújo 2 collaborations

Marcelo R Luizon 2 collaborations

César Sánchez 2 collaborations

Velia M Yufra-Picardo 2 collaborations

Adrián Llerena 2 collaborations

Daniel N Harris 2 collaborations

Alonso Soto 2 collaborations

Roberto Zegarra-Chapoñan 2 collaborations

Lucas A Michelin 2 collaborations

Marla M Aquino 2 collaborations

Andres Vasquez-Dominguez 2 collaborations

Timothy D O Connor 2 collaborations

Cesar Ugarte-Gil 2 collaborations

Marco Galarza 2 collaborations

Nathalia M Araújo 2 collaborations

Mateus H Gouveia 2 collaborations

Maíra R Rodrigues 2 collaborations

Sam M Mbulaiteye 2 collaborations

Sarah A Tishkoff 2 collaborations

Alexandre C Pereira 2 collaborations

Maria Fernanda Lima-Costa 2 collaborations

Marília O Scliar 2 collaborations

Kelly Nunes 2 collaborations

Diogo Meyer 2 collaborations

Víctor Borda 1 collaboration

Kelly Levano 1 collaboration

Omar Trujillo 1 collaboration

Pedro O Flores-Villanueva 1 collaboration

Silvia Fuselli 1 collaboration

Pedro E Romero 1 collaboration

Francesca Tassi 1 collaboration

Alberto Cisneros 1 collaboration

Marla Mendes de Aquino 1 collaboration

Isabela Rezende-Diniz 1 collaboration

Julia Saraiva-Duarte 1 collaboration

Lucas Faria-Costa 1 collaboration

Samira Asgari 1 collaboration

Yang Luo 1 collaboration

Ali Akbari 1 collaboration

Gillian M Belbin 1 collaboration

Xinyi Li 1 collaboration

Martin Selig 1 collaboration

Eric Bartell 1 collaboration

Roger Calderon 1 collaboration

Kamil Slowikowski 1 collaboration

Carmen Contreras 1 collaboration

Rosa Yataco 1 collaboration

Jerome T Galea 1 collaboration

Judith Jimenez 1 collaboration

Julia M Coit 1 collaboration

Chandel Farroñay 1 collaboration

Rosalynn M Nazarian 1 collaboration

Harry C Dietz 1 collaboration

Joel N Hirschhorn 1 collaboration

Leonid Lecca 1 collaboration

Eimear E Kenny 1 collaboration

Esther E Freeman 1 collaboration

Megan B Murray 1 collaboration

Soumya Raychaudhuri 1 collaboration

Tania Vásquez-Loarte 1 collaboration

Lely Solari 1 collaboration

Alberto Mendoza-Ticona 1 collaboration

Christian Rojas 1 collaboration

Ana Cecília Guimarães Alves 1 collaboration

Natalie Mary Sukow 1 collaboration

Gabriel Adelman Cipolla 1 collaboration

Maria Luiza Petzl-Erler 1 collaboration

Ricardo Lehtonen Rodrigues Souza 1 collaboration

Ilíada Rainha de Souza 1 collaboration

Meddly Santolalla 1 collaboration

Douglas Loesch 1 collaboration

Jee-Young Moon 1 collaboration

Robert Kaplan 1 collaboration

Kari E North 1 collaboration

Scott Weiss 1 collaboration

M Fernanda Lima-Costa 1 collaboration

Ignacio F Mata 1 collaboration

Elena Dieguez 1 collaboration

Víctor Raggio 1 collaboration

Andres Lescano 1 collaboration

Vitor Tumas 1 collaboration

Vanderci Borges 1 collaboration

Henrique B Ferraz 1 collaboration

Carlos R Rieder 1 collaboration

Artur Schumacher-Schuh 1 collaboration

Bruno L Santos-Lobato 1 collaboration

Pedro Chana-Cuevas 1 collaboration

William Fernandez 1 collaboration

Gonzalo Arboleda 1 collaboration

Humberto Arboleda 1 collaboration

Carlos E Arboleda-Bustos 1 collaboration

Marcia Holsbach Beltrame 1 collaboration

Murilo Pita-Oliveira 1 collaboration

Mariana M Scudeler 1 collaboration

Sabrina Torres-Loureiro 1 collaboration

Rennan Moreira 1 collaboration

Vinicius C Furlan 1 collaboration

Cesar Sanchez Neira 1 collaboration

Renato S Aguiar 1 collaboration

Ricardo A Verdugo 1 collaboration

Victor Aliaga-Tobar 1 collaboration

Oscar Pellon-Cardenas 1 collaboration

Henry L Gomez 1 collaboration

Mivael Olivera 1 collaboration

Vinicius Maracaja-Coutinho 1 collaboration

Rennan Garcias Moreira 1 collaboration

Julia Maria Saraiva-Duarte 1 collaboration

Alexandre Costa Pereira 1 collaboration

Martha Sosa-Macias 1 collaboration

Carlos Galaviz-Hernandez 1 collaboration

Meddly Lesley Santolalla 1 collaboration

Thiago Peixoto Leal 1 collaboration

Zsolt Balázs 1 collaboration

José Geraldo Mill 1 collaboration

Andrés Vásquez-Domínguez 1 collaboration

Rony Castrejon-Cabanillas 1 collaboration

Pedro Novoa-Bellota 1 collaboration

Marco Machacuay-Romero 1 collaboration

Ruth Garcia-de-la-Guarda 1 collaboration

Raul J Cano 1 collaboration

Ruth Shady Solis 1 collaboration

José Yareta 1 collaboration

Oscar Pellón 1 collaboration

Jorge Ballon 1 collaboration

Hanaisa P Sant'Anna 1 collaboration

Ricardo Lyra 1 collaboration

Lucas Michelin 1 collaboration

Sérgio V Peixoto 1 collaboration

Francisco Lobo 1 collaboration

Matthew E B Hansen 1 collaboration

Shane A Norris 1 collaboration

Ann W Hsing 1 collaboration

James Mensah 1 collaboration

Julie Dutil 1 collaboration

Edward Yeboah 1 collaboration

Ananyo Choudhury 1 collaboration

Michele Ramsay 1 collaboration

Jaqueline Y T Wang 1 collaboration

Jaqueline Yu Ting Wang 1 collaboration

Stepanka Zverinova 1 collaboration

Tatiana Karp 1 collaboration

José Ricardo Magliocco Ceroni 1 collaboration

Diego Lima de Carvalho 1 collaboration

Carlos Eduardo da Silva Simões 1 collaboration

Daniel Bozoklian 1 collaboration

Ricardo Nonaka 1 collaboration

Nayane Dos Santos Brito Silva 1 collaboration

Andreia da Silva Souza 1 collaboration

Heloísa de Souza Andrade 1 collaboration

Marília Rodrigues Silva Passos 1 collaboration

Camila Ferreira Bannwart Castro 1 collaboration

Celso T Mendes-Junior 1 collaboration

Rafael L V Mercuri 1 collaboration

Thiago L A Miller 1 collaboration

Jose Leonel Buzzo 1 collaboration

Fernanda O Rego 1 collaboration

Regina Célia Mingroni-Netto 1 collaboration

Carlos P Rojas 1 collaboration

Omar Caceres 1 collaboration

Pedro A F Galante 1 collaboration

Victor Guryev 1 collaboration

Erick C Castelli 1 collaboration

Gilmer Solis 1 collaboration

Rennan G Moreira 1 collaboration

Andrew W Bergen 1 collaboration

Gilderlanio S Araujo 1 collaboration

Nathalia M Araujo 1 collaboration

Raquel Liboredo 1 collaboration

Wagner C S Magalhaes 1 collaboration

Hanaisa P Sant Anna 1 collaboration

Giordano Soares-Souza 1 collaboration

Maria Catira Bortolini 1 collaboration

Jorge Rocha 1 collaboration

Maria F Lima-Costa 1 collaboration

Stephen J Chanock 1 collaboration

Isolina Villanueva 1 collaboration

Meylin Hidalgo 1 collaboration

Marco Cornejo 1 collaboration

Pilar Mazzetti 1 collaboration

Mario Cornejo-Olivas 1 collaboration

Ingo Ruczinski 1 collaboration

Lisa R Yanek 1 collaboration

Lewis C Becker 1 collaboration

Diane M Becker 1 collaboration

Tao Cui 1 collaboration

Floyd H Chilton 1 collaboration

Rasika A Mathias 1 collaboration

Anel Toledo-Nauto 1 collaboration