Heiko Hermeking

Affiliations

Experimental and Molecular Pathology, Institute of Pathology, Ludwig Maximilians University, München, Germany.
German Cancer Consortium (DKTK), Partner Site München, München, Germany.
German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publications (28)

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.

Nature communications

Avec: Amina Iftekhar , Hilmar Berger , Nassim Bouznad , Julian Heuberger , Francesco Boccellato , Ulrich Dobrindt , Heiko Hermeking , Michael Sigal , Thomas F Meyer

Cancers

Avec: Markus Kaller , Ignasi Forné , Axel Imhof , Heiko Hermeking

Analysis of the p53/microRNA Network in Cancer.

Advances in experimental medicine and biology

Avec: Markus Kaller , Sabine Hünten , Helge Siemens , Heiko Hermeking

Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer.

Cellular and molecular gastroenterology and hepatology

Avec: Xiaolong Shi , Markus Kaller , Matjaz Rokavec , Thomas Kirchner , David Horst , Heiko Hermeking

Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis.

Cellular and molecular gastroenterology and hepatology

Avec: Matjaz Rokavec , Nassim Bouznad , Heiko Hermeking

Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.

Cellular and molecular gastroenterology and hepatology

Avec: Sophie L Boos , Leon P Loevenich , Sebastian Vosberg , Thomas Engleitner , Rupert Öllinger , Jörg Kumbrink , Matjaz Rokavec , Marlies Michl , Philipp A Greif , Andreas Jung , Heiko Hermeking , Jens Neumann , Thomas Kirchner , Roland Rad , Peter Jung

Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis.

Atherosclerosis

Avec: Aikaterini Gatsiou , Georgios Georgiopoulos , Nikolaos I Vlachogiannis , Larissa Pfisterer , Ariane Fischer , Marco Sachse , Ageliki Laina , Francesca Bonini , Dimitrios Delialis , Simon Tual-Chalot , Eleftherios Zormpas , Rawlings Achangwa , Longchang Jiang , Christos Kontogiannis , Raphael Patras , Heiko Hermeking , Andreas M Zeiher , Kimon Stamatelopoulos , Stefanie Dimmeler , Konstantinos Stellos

Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with

International journal of biological sciences

Avec: Yuyun Du , Matjaz Rokavec , Heiko Hermeking

Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer.

Cell communication and signaling : CCS

Avec: Vanessa Dietinger , Cira R García de Durango , Svenja Wiechmann , Sophie L Boos , Marlies Michl , Jens Neumann , Heiko Hermeking , Bernhard Kuster , Peter Jung

Transcription Factor AP4 Mediates Cell Fate Decisions: To Divide, Age, or Die.

Cancers

Avec: Matthew Man-Kin Wong , Sancy Mary Joyson , Heiko Hermeking , Sung Kay Chiu

Erratum: Wagner, A.E., et al. SP8 Promotes an Aggressive Phenotype in Hepatoblastoma via FGF8 Activation.

Cancers

Avec: Alexandra Elisabeth Wagner , Thomas Schwarzmayr , Beate Häberle , Christian Vokuhl , Irene Schmid , Markus Kaller , Heiko Hermeking , Dietrich von Schweinitz , Roland Kappler

CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Rebecca Metzger , Lis Winter , Nassim Bouznad , Debora Garzetti , Benedikt von Armansperg , Matjaz Rokavec , Konstantin Lutz , Yvonne Schäfer , Sabrina Krebs , Elena Winheim , Verena Friedrich , Dana Matzek , Rupert Öllinger , Roland Rad , Bärbel Stecher , Heiko Hermeking , Thomas Brocker , Anne B Krug

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis.

Cell death and differentiation

Avec: Chunfeng Liu , Matjaz Rokavec , Zekai Huang , Heiko Hermeking

Myeloid Mir34a suppresses colitis-associated colon cancer: characterization of mediators by single-cell RNA sequencing.

Cell death and differentiation

Avec: Janine König , Matjaz Rokavec , Meryem Gülfem Öner-Ziegler , Ye Fei , Heiko Hermeking

Cancer research

Avec: Markus Winter , Matjaž Rokavec , Heiko Hermeking

Nidogen-1/NID1 Function and Regulation during Progression and Metastasis of Colorectal Cancer.

Cancers

Avec: Matjaz Rokavec , Stephanie Jaeckel , Heiko Hermeking

CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c in HCT116 colorectal cancer cells: comprehensive characterization after exposure to 5-FU reveals EMT and autophagy as key processes regulated by miR-34.

Cell death and differentiation

Avec: Zekai Huang , Markus Kaller , Heiko Hermeking

Salicylate induces AMPK and inhibits c-MYC to activate a NRF2/ARE/miR-34a/b/c cascade resulting in suppression of colorectal cancer metastasis.

Cell death & disease

Avec: Chunfeng Liu , Matjaz Rokavec , Zekai Huang , Heiko Hermeking

c-MYC-Induced AP4 Attenuates DREAM-Mediated Repression by p53.

Cancers

Avec: Markus Kaller , Wenjing Shi , Heiko Hermeking

Meta-analysis of miR-34 target mRNAs using an integrative online application.

Computational and structural biotechnology journal

Avec: Matjaz Rokavec , Zekai Huang , Heiko Hermeking

Mir34a constrains pancreatic carcinogenesis.

Scientific reports

Avec: Ana Hidalgo-Sastre , Clara Lubeseder-Martellato , Thomas Engleitner , Katja Steiger , Suyang Zhong , Judit Desztics , Rupert Öllinger , Roland Rad , Roland M Schmid , Heiko Hermeking , Jens T Siveke , Guido von Figura

Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing.

Methods in molecular biology (Clifton, N.J.)

Avec: Rene Jackstadt , Markus Kaller , Antje Menssen , Heiko Hermeking

AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG/miR-22-3p.

Molecular cancer

Avec: Jinjiang Chou , Markus Kaller , Stephanie Jaeckel , Matjaz Rokavec , Heiko Hermeking

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.

Cancer research

Avec: Leon P Loevenich , Markus Tschurtschenthaler , Matjaz Rokavec , Miguel G Silva , Moritz Jesinghaus , Thomas Kirchner , Frederick Klauschen , Dieter Saur , Jens Neumann , Heiko Hermeking , Peter Jung

In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.

Leukemia

Avec: Anna-Katharina Wirth , Lucas Wange , Sebastian Vosberg , Kai-Oliver Henrich , Christian Rausch , Erbey Özdemir , Christina M Zeller , Daniel Richter , Tobias Feuchtinger , Markus Kaller , Heiko Hermeking , Philipp A Greif , Daniela Senft , Vindi Jurinovic , Ehsan Bahrami , Ashok Kumar Jayavelu , Frank Westermann , Matthias Mann , Wolfgang Enard , Tobias Herold , Irmela Jeremias

International journal of biological sciences

Avec: Fangteng Liu , Nassim Bouznad , Markus Kaller , Xiaolong Shi , Janine König , Stephanie Jaeckel , Heiko Hermeking

miR-34a and IRE1A/XBP-1(S) Form a Double-Negative Feedback Loop to Regulate Hypoxia-Induced EMT, Metastasis, Chemo-Resistance and Autophagy.

Cancers

Avec: Nassim Bouznad , Matjaz Rokavec , Meryem Gülfem Öner , Heiko Hermeking

Development and Validation of a 15-gene Expression Signature with Superior Prognostic Ability in Stage II Colorectal Cancer.

Cancer research communications

Avec: Matjaz Rokavec , Elif Özcan , Jens Neumann , Heiko Hermeking

Réseau de co-auteurs

Matjaz Rokavec 14 collaborations

Markus Kaller 10 collaborations

Nassim Bouznad 5 collaborations

Jens Neumann 4 collaborations

Zekai Huang 4 collaborations

Thomas Kirchner 3 collaborations

Rupert Öllinger 3 collaborations

Roland Rad 3 collaborations

Peter Jung 3 collaborations

Stephanie Jaeckel 3 collaborations

Xiaolong Shi 2 collaborations

Sophie L Boos 2 collaborations

Leon P Loevenich 2 collaborations

Sebastian Vosberg 2 collaborations

Thomas Engleitner 2 collaborations

Marlies Michl 2 collaborations

Philipp A Greif 2 collaborations

Chunfeng Liu 2 collaborations

Janine König 2 collaborations

Amina Iftekhar 1 collaboration

Hilmar Berger 1 collaboration

Julian Heuberger 1 collaboration

Francesco Boccellato 1 collaboration

Ulrich Dobrindt 1 collaboration

Michael Sigal 1 collaboration

Thomas F Meyer 1 collaboration

Ignasi Forné 1 collaboration

Axel Imhof 1 collaboration

Sabine Hünten 1 collaboration

Helge Siemens 1 collaboration

David Horst 1 collaboration

Jörg Kumbrink 1 collaboration

Andreas Jung 1 collaboration

Aikaterini Gatsiou 1 collaboration

Georgios Georgiopoulos 1 collaboration

Nikolaos I Vlachogiannis 1 collaboration

Larissa Pfisterer 1 collaboration

Ariane Fischer 1 collaboration

Marco Sachse 1 collaboration

Ageliki Laina 1 collaboration

Francesca Bonini 1 collaboration

Dimitrios Delialis 1 collaboration

Simon Tual-Chalot 1 collaboration

Eleftherios Zormpas 1 collaboration

Rawlings Achangwa 1 collaboration

Longchang Jiang 1 collaboration

Christos Kontogiannis 1 collaboration

Raphael Patras 1 collaboration

Andreas M Zeiher 1 collaboration

Kimon Stamatelopoulos 1 collaboration

Stefanie Dimmeler 1 collaboration

Konstantinos Stellos 1 collaboration

Yuyun Du 1 collaboration

Vanessa Dietinger 1 collaboration

Cira R García de Durango 1 collaboration

Svenja Wiechmann 1 collaboration

Bernhard Kuster 1 collaboration

Matthew Man-Kin Wong 1 collaboration

Sancy Mary Joyson 1 collaboration

Sung Kay Chiu 1 collaboration

Alexandra Elisabeth Wagner 1 collaboration

Thomas Schwarzmayr 1 collaboration

Beate Häberle 1 collaboration

Christian Vokuhl 1 collaboration

Irene Schmid 1 collaboration

Dietrich von Schweinitz 1 collaboration

Roland Kappler 1 collaboration

Rebecca Metzger 1 collaboration

Lis Winter 1 collaboration

Debora Garzetti 1 collaboration

Benedikt von Armansperg 1 collaboration

Konstantin Lutz 1 collaboration

Yvonne Schäfer 1 collaboration

Sabrina Krebs 1 collaboration

Elena Winheim 1 collaboration

Verena Friedrich 1 collaboration

Dana Matzek 1 collaboration

Bärbel Stecher 1 collaboration

Thomas Brocker 1 collaboration

Anne B Krug 1 collaboration

Meryem Gülfem Öner-Ziegler 1 collaboration

Ye Fei 1 collaboration

Markus Winter 1 collaboration

Matjaž Rokavec 1 collaboration

Wenjing Shi 1 collaboration

Ana Hidalgo-Sastre 1 collaboration

Clara Lubeseder-Martellato 1 collaboration

Katja Steiger 1 collaboration

Suyang Zhong 1 collaboration

Judit Desztics 1 collaboration

Roland M Schmid 1 collaboration

Jens T Siveke 1 collaboration

Guido von Figura 1 collaboration

Rene Jackstadt 1 collaboration

Antje Menssen 1 collaboration

Jinjiang Chou 1 collaboration

Markus Tschurtschenthaler 1 collaboration

Miguel G Silva 1 collaboration

Moritz Jesinghaus 1 collaboration

Frederick Klauschen 1 collaboration

Dieter Saur 1 collaboration

Anna-Katharina Wirth 1 collaboration

Lucas Wange 1 collaboration

Kai-Oliver Henrich 1 collaboration

Christian Rausch 1 collaboration

Erbey Özdemir 1 collaboration

Christina M Zeller 1 collaboration

Daniel Richter 1 collaboration

Tobias Feuchtinger 1 collaboration

Daniela Senft 1 collaboration

Vindi Jurinovic 1 collaboration

Ehsan Bahrami 1 collaboration

Ashok Kumar Jayavelu 1 collaboration

Frank Westermann 1 collaboration

Matthias Mann 1 collaboration

Wolfgang Enard 1 collaboration

Tobias Herold 1 collaboration

Irmela Jeremias 1 collaboration

Fangteng Liu 1 collaboration

Meryem Gülfem Öner 1 collaboration

Elif Özcan 1 collaboration