Hannah K Shorrock

Affiliations

Edinburgh Medical School, Biomedical Sciences, College of Medicine & Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.

Publications (10)

Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect.

The Journal of clinical investigation

Avec: Haiyan Zhou , Ying Hong , Mariacristina Scoto , Alison Thomson , Emma Pead , Tom MacGillivray , Elena Hernandez-Gerez , Francesco Catapano , Jinhong Meng , Qiang Zhang , Gillian Hunter , Hannah K Shorrock , Thomas K Ng , Abedallah Hamida , Mathilde Sanson , Giovanni Baranello , Kevin Howell , Thomas H Gillingwater , Paul Brogan , Dorothy A Thompson , Simon H Parson , Francesco Muntoni

Lamin A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy.

Human molecular genetics

Avec: Darija Šoltić , Hannah K Shorrock , Hazel Allardyce , Emma L Wilson , Ian Holt , Silvia A Synowsky , Sally L Shirran , Simon H Parson , Thomas H Gillingwater , Heidi R Fuller

Widespread alternative splicing dysregulation occurs presymptomatically in CAG expansion spinocerebellar ataxias.

Brain : a journal of neurology

Avec: Hannah K Shorrock , Claudia D Lennon , Asmer Aliyeva , Emily E Davey , Cristina C DeMeo , Caroline E Pritchard , Lori Planco , Jose M Velez , Alexandra Mascorro-Huamancaja , Damian S Shin , John D Cleary , J Andrew Berglund

CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs.

bioRxiv : the preprint server for biology

Avec: Hannah K Shorrock , Asmer Aliyeva , Jesus A Frias , Victoria A DeMeo , Claudia D Lennon , Cristina C DeMeo , Amy K Mascorro , Sharon Shaughnessy , Hormoz Mazdiyasni , John D Cleary , Kaalak Reddy , Sweta Vangaveti , Damian S Shin , J Andrew Berglund

CCG•CGG interruptions in high-penetrance SCA8 families increase RAN translation and protein toxicity.

EMBO molecular medicine

Avec: Barbara A Perez , Hannah K Shorrock , Monica Banez-Coronel , Tao Zu , Lisa El Romano , Lauren A Laboissonniere , Tammy Reid , Yoshio Ikeda , Kaalak Reddy , Christopher M Gomez , Thomas Bird , Tetsuo Ashizawa , Lawrence J Schut , Alfredo Brusco , J Andrew Berglund , Lis F Hasholt , Jorgen E Nielsen , S H Subramony , Laura Pw Ranum

Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening.

iScience

Avec: Jana R Jenquin , Alana P O'Brien , Kiril Poukalov , Yidan Lu , Jesus A Frias , Hannah K Shorrock , Jared I Richardson , Hormoz Mazdiyasni , Hongfen Yang , Robert W Huigens , David Boykin , Laura P W Ranum , John Douglas Cleary , Eric T Wang , J Andrew Berglund

AAV9-mediated SMN gene therapy rescues cardiac desmin but not lamin A/C and elastin dysregulation in Smn2B/- spinal muscular atrophy mice.

Human molecular genetics

Avec: Sharon J Brown , Darija Šoltić , Silvia A Synowsky , Sally L Shirran , Ellie Chilcott , Hannah K Shorrock , Thomas H Gillingwater , Rafael J Yáñez-Muñoz , Bernard Schneider , Melissa Bowerman , Heidi R Fuller

Molecular Mechanisms Underlying Sensory-Motor Circuit Dysfunction in SMA.

Frontiers in molecular neuroscience

Avec: Hannah K Shorrock , Thomas H Gillingwater , Ewout J N Groen

Disease-associated inosine misincorporation into RNA hinders translation.

Nucleic acids research

Avec: Jacob H Schroader , Lindsey A Jones , Ryan Meng , Hannah K Shorrock , Jared I Richardson , Sharon M Shaughnessy , Qishan Lin , Thomas J Begley , J Andrew Berglund , Gabriele Fuchs , Mark T Handley , Kaalak Reddy

Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1.

JCI insight

Avec: Emily E Davey , Cécilia Légaré , Lori Planco , Sharon Shaughnessy , Claudia D Lennon , Marie-Pier Roussel , Hannah K Shorrock , Man Hung , John Douglas Cleary , Elise Duchesne , J Andrew Berglund

Réseau de co-auteurs

J Andrew Berglund 6 collaborations

Thomas H Gillingwater 4 collaborations

Claudia D Lennon 3 collaborations

Kaalak Reddy 3 collaborations

Simon H Parson 2 collaborations

Darija Šoltić 2 collaborations

Silvia A Synowsky 2 collaborations

Sally L Shirran 2 collaborations

Heidi R Fuller 2 collaborations

Asmer Aliyeva 2 collaborations

Emily E Davey 2 collaborations

Cristina C DeMeo 2 collaborations

Lori Planco 2 collaborations

Damian S Shin 2 collaborations

John D Cleary 2 collaborations

Jesus A Frias 2 collaborations

Sharon Shaughnessy 2 collaborations

Hormoz Mazdiyasni 2 collaborations

Jared I Richardson 2 collaborations

John Douglas Cleary 2 collaborations

Haiyan Zhou 1 collaboration

Ying Hong 1 collaboration

Mariacristina Scoto 1 collaboration

Alison Thomson 1 collaboration

Emma Pead 1 collaboration

Tom MacGillivray 1 collaboration

Elena Hernandez-Gerez 1 collaboration

Francesco Catapano 1 collaboration

Jinhong Meng 1 collaboration

Qiang Zhang 1 collaboration

Gillian Hunter 1 collaboration

Thomas K Ng 1 collaboration

Abedallah Hamida 1 collaboration

Mathilde Sanson 1 collaboration

Giovanni Baranello 1 collaboration

Kevin Howell 1 collaboration

Paul Brogan 1 collaboration

Dorothy A Thompson 1 collaboration

Francesco Muntoni 1 collaboration

Hazel Allardyce 1 collaboration

Emma L Wilson 1 collaboration

Ian Holt 1 collaboration

Caroline E Pritchard 1 collaboration

Jose M Velez 1 collaboration

Alexandra Mascorro-Huamancaja 1 collaboration

Victoria A DeMeo 1 collaboration

Amy K Mascorro 1 collaboration

Sweta Vangaveti 1 collaboration

Barbara A Perez 1 collaboration

Monica Banez-Coronel 1 collaboration

Tao Zu 1 collaboration

Lisa El Romano 1 collaboration

Lauren A Laboissonniere 1 collaboration

Tammy Reid 1 collaboration

Yoshio Ikeda 1 collaboration

Christopher M Gomez 1 collaboration

Thomas Bird 1 collaboration

Tetsuo Ashizawa 1 collaboration

Lawrence J Schut 1 collaboration

Alfredo Brusco 1 collaboration

Lis F Hasholt 1 collaboration

Jorgen E Nielsen 1 collaboration

S H Subramony 1 collaboration

Laura Pw Ranum 1 collaboration

Jana R Jenquin 1 collaboration

Alana P O'Brien 1 collaboration

Kiril Poukalov 1 collaboration

Yidan Lu 1 collaboration

Hongfen Yang 1 collaboration

Robert W Huigens 1 collaboration

David Boykin 1 collaboration

Laura P W Ranum 1 collaboration

Eric T Wang 1 collaboration

Sharon J Brown 1 collaboration

Ellie Chilcott 1 collaboration

Rafael J Yáñez-Muñoz 1 collaboration

Bernard Schneider 1 collaboration

Melissa Bowerman 1 collaboration

Ewout J N Groen 1 collaboration

Jacob H Schroader 1 collaboration

Lindsey A Jones 1 collaboration

Ryan Meng 1 collaboration

Sharon M Shaughnessy 1 collaboration

Qishan Lin 1 collaboration

Thomas J Begley 1 collaboration

Gabriele Fuchs 1 collaboration

Mark T Handley 1 collaboration

Cécilia Légaré 1 collaboration

Marie-Pier Roussel 1 collaboration

Man Hung 1 collaboration

Elise Duchesne 1 collaboration