Giordano Pula

Affiliations

Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, UK.

Publications (24)

Amyloid Peptide

Oxidative medicine and cellular longevity

Avec: Aisha Alsheikh Abubaker , Dina Vara , Caterina Visconte , Ian Eggleston , Mauro Torti , Ilaria Canobbio , Giordano Pula

Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function.

Free radical biology & medicine

Avec: Renato Simões Gaspar , Plinio M Ferreira , Joanne L Mitchell , Giordano Pula , Jonathan M Gibbins

Fibrillar amyloid peptides promote platelet aggregation through the coordinated action of ITAM- and ROS-dependent pathways.

Journal of thrombosis and haemostasis : JTH

Avec: Caterina Visconte , Jessica Canino , Mauro Vismara , Gianni Francesco Guidetti , Sara Raimondi , Giordano Pula , Mauro Torti , Ilaria Canobbio

Identification of the factor XII contact activation site enables sensitive coagulation diagnostics.

Nature communications

Avec: Marco Heestermans , Clément Naudin , Reiner K Mailer , Sandra Konrath , Kristin Klaetschke , Anne Jämsä , Maike Frye , Carsten Deppermann , Giordano Pula , Piotr Kuta , Manuel A Friese , Mathias Gelderblom , Albert Sickmann , Roger J S Preston , Jerzy-Roch Nofer , Stefan Rose-John , Lynn M Butler , Ophira Salomon , Evi X Stavrou , Thomas Renné

Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.

Nature communications

Avec: Ah-Lai Law , Shamsinar Jalal , Tommy Pallett , Fuad Mosis , Ahmad Guni , Simon Brayford , Lawrence Yolland , Stefania Marcotti , James A Levitt , Simon P Poland , Maia Rowe-Sampson , Anett Jandke , Robert Köchl , Giordano Pula , Simon M Ameer-Beg , Brian Marc Stramer , Matthias Krause

Antiplatelet drugs do not protect from platelet-leukocyte aggregation in coronary artery disease.

Journal of thrombosis and haemostasis : JTH

Avec: Christian Schulte , Luise Pieper , Maike Frye , Christoph Waldeyer , Johannes T Neumann , Fabian J Brunner , Giordano Pula

A novel combinatorial technique for simultaneous quantification of oxygen radicals and aggregation reveals unexpected redox patterns in the activation of platelets by different physiopathological stimuli.

Haematologica

Avec: Dina Vara , Eugenia Cifuentes-Pagano , Patrick J Pagano , Giordano Pula

Diabetes and Thrombosis: A Central Role for Vascular Oxidative Stress.

Antioxidants (Basel, Switzerland)

Avec: Aishwarya R Vaidya , Nina Wolska , Dina Vara , Reiner K Mailer , Katrin Schröder , Giordano Pula

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Dina Vara , Reiner K Mailer , Anuradha Tarafdar , Nina Wolska , Marco Heestermans , Sandra Konrath , Manuela Spaeth , Thomas Renné , Katrin Schröder , Giordano Pula

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate.

Blood

Avec: Reiner K Mailer , Mikel Allende , Marco Heestermans , Michaela Schweizer , Carsten Deppermann , Maike Frye , Giordano Pula , Jacob Odeberg , Mathias Gelderblom , Stefan Rose-John , Albert Sickmann , Stefan Blankenberg , Tobias B Huber , Christian Kubisch , Coen Maas , Stepan Gambaryan , Dmitri Firsov , Evi X Stavrou , Lynn M Butler , Thomas Renné

The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner.

Redox biology

Avec: Anuradha Tarafdar , Nina Wolska , Christoph Krisp , Hartmut Schlüter , Giordano Pula

Human platelets release amyloid peptides β

Research and practice in thrombosis and haemostasis

Avec: Nina Wolska , Meral Celikag , Antonio Virgilio Failla , Anuradha Tarafdar , Thomas Renné , Mauro Torti , Ilaria Canobbio , Giordano Pula

Coercion and Compulsory Treatment in Anorexia Nervosa: a Systematic Review on Legal and Ethical Issues.

Psychiatria Danubina

Avec: Agnese Minuti , Sara Bianchi , Grazia Pula , Andreina Perlangeli , Martina Tardani , Lorenzo Cuzzucoli , Laura Pastorino , Giulia Menculini , Patrizia Moretti

Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation.

EBioMedicine

Avec: Hanna Englert , Chandini Rangaswamy , Carsten Deppermann , Jan-Peter Sperhake , Christoph Krisp , Danny Schreier , Emma Gordon , Sandra Konrath , Munif Haddad , Giordano Pula , Reiner K Mailer , Hartmut Schlüter , Stefan Kluge , Florian Langer , Klaus Püschel , Kosta Panousis , Evi X Stavrou , Coen Maas , Thomas Renné , Maike Frye

Zinc regulates reactive oxygen species generation in platelets.

Platelets

Avec: M E Lopes-Pires , N S Ahmed , D Vara , J M Gibbins , G Pula , N Pugh

NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Dina Vara , Anuradha Tarafdar , Meral Celikag , Daniela Patinha , Christina E Gulacsy , Ellie Hounslea , Zach Warren , Barbara Ferreira , Maarten P Koeners , Lorenzo Caggiano , Giordano Pula

A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes.

Journal of thrombosis and haemostasis : JTH

Avec: Stuart Wallis , Nina Wolska , Hanna Englert , Mareike Posner , Abhishek Upadhyay , Thomas Renné , Ian Eggleston , Stefan Bagby , Giordano Pula

Development of new peptidomimetic NADPH oxidase inhibitors with antithrombotic properties.

ChemMedChem

Avec: Elisabetta Scalia , Antony Chirco , Lorenzo Calugi , Elena Lenci , Patrick J Pagano , Giordano Pula , Andrea Trabocchi

Patient-tailored platelet transfusion practices for children supported by extracorporeal membrane oxygenation.

Vox sanguinis

Avec: Ofer Schiller , Giulia Pula , Eran Shostak , Orit Manor-Shulman , Georgy Frenkel , Gabriel Amir , Joanne Yacobovich , Marianne E Nellis , Ovadia Dagan

A novel flow cytometry assay using dihydroethidium as redox-sensitive probe reveals NADPH oxidase-dependent generation of superoxide anion in human platelets exposed to amyloid peptide β.

Platelets

Avec: Aisha Alsheikh Abubaker , Dina Vara , Ian Eggleston , Ilaria Canobbio , Giordano Pula

Protein Disulphide Isomerase and NADPH Oxidase 1 Cooperate to Control Platelet Function and Are Associated with Cardiometabolic Disease Risk Factors.

Antioxidants (Basel, Switzerland)

Avec: Renato Simões Gaspar , Tanya Sage , Gemma Little , Neline Kriek , Giordano Pula , Jonathan M Gibbins

Alternative Methods for the Detection of Superoxide Anion Generation in Platelets.

Journal of visualized experiments : JoVE

Avec: Dina Vara , Sophie Leonard , Simon Calaminus , Giordano Pula

The Effect of Medical Clowns on Blood Pressure Measurement in Children Presenting to the Emergency Department.

The Israel Medical Association journal : IMAJ

Avec: Ayelet Shles , Giulia Pula , Omer Raviv , Dania Takagi , Hadas Yechiam , Ehud Rosenbloom

Psychological Assessment in Anorexia Nervosa: A Single Case Study on Predictive Factors of Dropout.

Psychiatria Danubina

Avec: Veronica Raspa , Patrizia Moretti , Grazia Pula , Giulia Menculini , Claudia Mazzeschi , Alfonso Tortorella

Réseau de co-auteurs

Dina Vara 7 collaborations

Thomas Renné 6 collaborations

Reiner K Mailer 5 collaborations

Nina Wolska 5 collaborations

Ilaria Canobbio 4 collaborations

Maike Frye 4 collaborations

Anuradha Tarafdar 4 collaborations

Ian Eggleston 3 collaborations

Mauro Torti 3 collaborations

Marco Heestermans 3 collaborations

Sandra Konrath 3 collaborations

Carsten Deppermann 3 collaborations

Evi X Stavrou 3 collaborations

Aisha Alsheikh Abubaker 2 collaborations

Caterina Visconte 2 collaborations

Renato Simões Gaspar 2 collaborations

Jonathan M Gibbins 2 collaborations

Mathias Gelderblom 2 collaborations

Albert Sickmann 2 collaborations

Stefan Rose-John 2 collaborations

Lynn M Butler 2 collaborations

Patrick J Pagano 2 collaborations

Katrin Schröder 2 collaborations

Coen Maas 2 collaborations

Christoph Krisp 2 collaborations

Hartmut Schlüter 2 collaborations

Meral Celikag 2 collaborations

Grazia Pula 2 collaborations

Giulia Menculini 2 collaborations

Patrizia Moretti 2 collaborations

Hanna Englert 2 collaborations

Giulia Pula 2 collaborations

Plinio M Ferreira 1 collaboration

Joanne L Mitchell 1 collaboration

Jessica Canino 1 collaboration

Mauro Vismara 1 collaboration

Gianni Francesco Guidetti 1 collaboration

Sara Raimondi 1 collaboration

Clément Naudin 1 collaboration

Kristin Klaetschke 1 collaboration

Anne Jämsä 1 collaboration

Piotr Kuta 1 collaboration

Manuel A Friese 1 collaboration

Roger J S Preston 1 collaboration

Jerzy-Roch Nofer 1 collaboration

Ophira Salomon 1 collaboration

Ah-Lai Law 1 collaboration

Shamsinar Jalal 1 collaboration

Tommy Pallett 1 collaboration

Fuad Mosis 1 collaboration

Ahmad Guni 1 collaboration

Simon Brayford 1 collaboration

Lawrence Yolland 1 collaboration

Stefania Marcotti 1 collaboration

James A Levitt 1 collaboration

Simon P Poland 1 collaboration

Maia Rowe-Sampson 1 collaboration

Anett Jandke 1 collaboration

Robert Köchl 1 collaboration

Simon M Ameer-Beg 1 collaboration

Brian Marc Stramer 1 collaboration

Matthias Krause 1 collaboration

Christian Schulte 1 collaboration

Luise Pieper 1 collaboration

Christoph Waldeyer 1 collaboration

Johannes T Neumann 1 collaboration

Fabian J Brunner 1 collaboration

Eugenia Cifuentes-Pagano 1 collaboration

Aishwarya R Vaidya 1 collaboration

Manuela Spaeth 1 collaboration

Mikel Allende 1 collaboration

Michaela Schweizer 1 collaboration

Jacob Odeberg 1 collaboration

Stefan Blankenberg 1 collaboration

Tobias B Huber 1 collaboration

Christian Kubisch 1 collaboration

Stepan Gambaryan 1 collaboration

Dmitri Firsov 1 collaboration

Antonio Virgilio Failla 1 collaboration

Agnese Minuti 1 collaboration

Sara Bianchi 1 collaboration

Andreina Perlangeli 1 collaboration

Martina Tardani 1 collaboration

Lorenzo Cuzzucoli 1 collaboration

Laura Pastorino 1 collaboration

Chandini Rangaswamy 1 collaboration

Jan-Peter Sperhake 1 collaboration

Danny Schreier 1 collaboration

Emma Gordon 1 collaboration

Munif Haddad 1 collaboration

Stefan Kluge 1 collaboration

Florian Langer 1 collaboration

Klaus Püschel 1 collaboration

Kosta Panousis 1 collaboration

M E Lopes-Pires 1 collaboration

N S Ahmed 1 collaboration

D Vara 1 collaboration

J M Gibbins 1 collaboration

G Pula 1 collaboration

N Pugh 1 collaboration

Daniela Patinha 1 collaboration

Christina E Gulacsy 1 collaboration

Ellie Hounslea 1 collaboration

Zach Warren 1 collaboration

Barbara Ferreira 1 collaboration

Maarten P Koeners 1 collaboration

Lorenzo Caggiano 1 collaboration

Stuart Wallis 1 collaboration

Mareike Posner 1 collaboration

Abhishek Upadhyay 1 collaboration

Stefan Bagby 1 collaboration

Elisabetta Scalia 1 collaboration

Antony Chirco 1 collaboration

Lorenzo Calugi 1 collaboration

Elena Lenci 1 collaboration

Andrea Trabocchi 1 collaboration

Ofer Schiller 1 collaboration

Eran Shostak 1 collaboration

Orit Manor-Shulman 1 collaboration

Georgy Frenkel 1 collaboration

Gabriel Amir 1 collaboration

Joanne Yacobovich 1 collaboration

Marianne E Nellis 1 collaboration

Ovadia Dagan 1 collaboration

Tanya Sage 1 collaboration

Gemma Little 1 collaboration

Neline Kriek 1 collaboration

Sophie Leonard 1 collaboration

Simon Calaminus 1 collaboration

Ayelet Shles 1 collaboration

Omer Raviv 1 collaboration

Dania Takagi 1 collaboration

Hadas Yechiam 1 collaboration

Ehud Rosenbloom 1 collaboration

Veronica Raspa 1 collaboration

Claudia Mazzeschi 1 collaboration

Alfonso Tortorella 1 collaboration