Gianluca Cruciani

Affiliations

Department of Psychology, PhD Program in Behavioral Neuroscience, Sapienza University of Rome, Via dei Marsi 78, Rome, Italy. Electronic address: gianluca.cruciani@uniroma1.it.

Publications (31)

Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases.

Scientific reports

Avec: Francesca Spyrakis , Matteo Santucci , Lorenzo Maso , Simon Cross , Eleonora Gianquinto , Filomena Sannio , Federica Verdirosa , Filomena De Luca , Jean-Denis Docquier , Laura Cendron , Donatella Tondi , Alberto Venturelli , Gabriele Cruciani , Maria Paola Costi

Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Nicolo Milani , NaHong Qiu , Birgit Molitor , Justine Badée , Gabriele Cruciani , Stephen Fowler

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.

Science translational medicine

Avec: Ibrahim Boussaad , Carolin D Obermaier , Zoé Hanss , Dheeraj R Bobbili , Silvia Bolognin , Enrico Glaab , Katarzyna Wołyńska , Nicole Weisschuh , Laura De Conti , Caroline May , Florian Giesert , Dajana Grossmann , Annika Lambert , Susanne Kirchen , Maria Biryukov , Lena F Burbulla , Francois Massart , Jill Bohler , Gérald Cruciani , Benjamin Schmid , Annerose Kurz-Drexler , Patrick May , Stefano Duga , Christine Klein , Jens C Schwamborn , Katrin Marcus , Dirk Woitalla , Daniela M Vogt Weisenhorn , Wolfgang Wurst , Marco Baralle , Dimitri Krainc , Thomas Gasser , Bernd Wissinger , Rejko Krüger

Synthetic Peptide Libraries: From Random Mixtures to In Vivo Testing.

Current medicinal chemistry

Avec: Annamaria Sandomenico , Andrea Caporale , Nunzianna Doti , Simon Cross , Gabriele Cruciani , Angela Chambery , Sandro De Falco , Menotti Ruvo

Nutritional and lipidomics biomarkers of docosahexaenoic acid-based multivitamin therapy in pediatric NASH.

Scientific reports

Avec: Pierangelo Torquato , Danilo Giusepponi , Anna Alisi , Roberta Galarini , Desirée Bartolini , Marta Piroddi , Laura Goracci , Alessandra Di Veroli , Gabriele Cruciani , Annalisa Crudele , Valerio Nobili , Francesco Galli

Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia.

Cell death & disease

Avec: Maurizio Gianni' , Laura Goracci , Anna Schlaefli , Alessandra Di Veroli , Mami Kurosaki , Luca Guarrera , Marco Bolis , Marika Foglia , Monica Lupi , Mario P Tschan , Gabriele Cruciani , Mineko Terao , Enrico Garattini

SARS-CoV-2 Survival on Surfaces and the Effect of UV-C Light.

Viruses

Avec: Anna Gidari , Samuele Sabbatini , Sabrina Bastianelli , Sara Pierucci , Chiara Busti , Desirée Bartolini , Anna Maria Stabile , Claudia Monari , Francesco Galli , Mario Rende , Gabriele Cruciani , Daniela Francisci

Technological insights on the Early-Middle Bronze Age pottery of Monte Meana cave (Sardinia, Italy).

Heliyon

Avec: Giacomo Paglietti , Giuseppa Tanda , Rita Teresa Melis , Anna Musinu , Gabriele Cruciani , Marcello Franceschelli , Carla Cannas , Valentina Mameli , Mariano Casu

Endoplasmic reticulum stress and NF-kB activation in SARS-CoV-2 infected cells and their response to antiviral therapy.

IUBMB life

Avec: Desirée Bartolini , Anna Maria Stabile , Carmine Vacca , Alessandra Pistilli , Mario Rende , Antimo Gioiello , Gabriele Cruciani , Francesco Galli

Combining machine learning and quantum mechanics yields more chemically aware molecular descriptors for medicinal chemistry applications.

Journal of computational chemistry

Avec: Sara Tortorella , Emanuele Carosati , Giulia Sorbi , Giovanni Bocci , Simon Cross , Gabriele Cruciani , Loriano Storchi

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A.

Journal of enzyme inhibition and medicinal chemistry

Avec: Roberta Pacifico , Nunzio Del Gaudio , Guglielmo Bove , Lucia Altucci , Lydia Siragusa , Gabriele Cruciani , Menotti Ruvo , Rosa Bellavita , Paolo Grieco , Mauro F A Adamo

Exploring Ligand Binding Domain Dynamics in the NRs Superfamily.

International journal of molecular sciences

Avec: Giulia D'Arrigo , Ida Autiero , Eleonora Gianquinto , Lydia Siragusa , Massimo Baroni , Gabriele Cruciani , Francesca Spyrakis

The perception of pain, discriminative touch and affective touch in patients suffering from Borderline Personality Disorder.

Journal of affective disorders

Avec: Gianluca Cruciani , Pietro Zingaretti , Vittorio Lingiardi , Sergio De Filippis , Patrick Haggard , Grazia Fernanda Spitoni

DeepGRID: Deep Learning Using GRID Descriptors for BBB Prediction.

Journal of chemical information and modeling

Avec: Loriano Storchi , Gabriele Cruciani , Simon Cross

Heart rate variability alterations in takotsubo syndrome and related association with psychological factors: a systematic review and meta-analysis.

Scientific reports

Avec: Gianluca Cruciani , Marco Cavicchioli , Gaetano Tanzilli , Annalisa Tanzilli , Vittorio Lingiardi , Federica Galli

Structure Evolution of Ge-Doped CaTiO

Inorganic chemistry

Avec: Matteo Ardit , Sonia Conte , Donato Belmonte , Francesca Menescardi , Simone Pollastri , Giuseppe Cruciani , Michele Dondi

Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.

eLife

Avec: Luca Costantino , Stefania Ferrari , Matteo Santucci , Outi M H Salo-Ahen , Emanuele Carosati , Silvia Franchini , Angela Lauriola , Cecilia Pozzi , Matteo Trande , Gaia Gozzi , Puneet Saxena , Giuseppe Cannazza , Lorena Losi , Daniela Cardinale , Alberto Venturelli , Antonio Quotadamo , Pasquale Linciano , Lorenzo Tagliazucchi , Maria Gaetana Moschella , Remo Guerrini , Salvatore Pacifico , Rosaria Luciani , Filippo Genovese , Stefan Henrich , Silvia Alboni , Nuno Santarem , Anabela da Silva Cordeiro , Elisa Giovannetti , Godefridus J Peters , Paolo Pinton , Alessandro Rimessi , Gabriele Cruciani , Robert M Stroud , Rebecca C Wade , Stefano Mangani , Gaetano Marverti , Domenico D'Arca , Glauco Ponterini , Maria Paola Costi

Physico-Mechanical Performances of Mortars Prepared with Sorted Earthquake Rubble: The Role of CDW Type and Contained Crystalline Phases.

Materials (Basel, Switzerland)

Avec: Antonio Galderisi , Miguel Bravo , Gianluca Iezzi , Giuseppe Cruciani , Eleonora Paris , Jorge de Brito

Between Theory and Practice: Computational/Experimental Integrated Approaches to Understand the Solubility and Lipophilicity of PROTACs.

Journal of medicinal chemistry

Avec: Andrea Venturi , Stefano Di Bona , Jenny Desantis , Michela Eleuteri , Matteo Bartalucci , Massimo Baroni , Paolo Benedetti , Laura Goracci , Gabriele Cruciani

Attitudes and knowledge of mental health practitioners towards LGBTQ+ patients: A mixed-method systematic review.

Clinical psychology review

Avec: Gianluca Cruciani , Maria Quintigliano , Selene Mezzalira , Cristiano Scandurra , Nicola Carone

A liquid chromatography-high resolution mass spectrometry method for the determination of thirty-three per- and polyfluoroalkyl substances in animal liver.

Journal of chromatography. A

Avec: Carolina Barola , Simone Moretti , Danilo Giusepponi , Fabiola Paoletti , Giorgio Saluti , Gabriele Cruciani , Gianfranco Brambilla , Roberta Galarini

Geochemical and geochronological dataset of rutile from a Variscan metabasite in Sardinia, Italy.

Data in brief

Avec: Gabriele Cruciani , Dario Fancello , Marcello Franceschelli , Hans-Joachim Massonne , Antonio Langone , Massimo Scodina

Disorganized Attachment pattern affects the perception of Affective Touch.

Scientific reports

Avec: Grazia Fernanda Spitoni , Pietro Zingaretti , Guido Giovanardi , Gabriella Antonucci , Gaspare Galati , Vittorio Lingiardi , Gianluca Cruciani , Giulia Titone , Maddalena Boccia

Heart rate variability in response to the recall of attachment memories.

Attachment & human development

Avec: Pietro Zingaretti , Guido Giovanardi , Gianluca Cruciani , Vittorio Lingiardi , Cristina Ottaviani , Grazia Fernanda Spitoni

How computational chemistry develops: a tribute to Peter Goodford.

Journal of computer-aided molecular design

Avec: Gabriele Cruciani , Yvonne Martin , Andy Vinter , Richard Lewis , Federico Gago , Terry R Stouch

Nanostructured SmFeO

Sensors (Basel, Switzerland)

Avec: Andrea Gaiardo , Giulia Zonta , Sandro Gherardi , Cesare Malagù , Barbara Fabbri , Matteo Valt , Lia Vanzetti , Nicolò Landini , Davide Casotti , Giuseppe Cruciani , Michele Della Ciana , Vincenzo Guidi

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function.

Scientific reports

Avec: Peter A Barbuti , Jochen Ohnmacht , Bruno F R Santos , Paul M Antony , François Massart , Gérald Cruciani , Claire M Dording , Lukas Pavelka , Nicolas Casadei , Yong-Jun Kwon , Rejko Krüger

Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis.

Haematologica

Avec: Alberto J Arribas , Sara Napoli , Luciano Cascione , Giulio Sartori , Laura Barnabei , Eugenio Gaudio , Chiara Tarantelli , Afua Adjeiwaa Mensah , Filippo Spriano , Antonella Zucchetto , Francesca M Rossi , Andrea Rinaldi , Manuel Castro de Moura , Sandra Jovic , Roberta Bordone-Pittau , Alessandra Di Veroli , Anastasios Stathis , Gabriele Cruciani , Georg Stussi , Valter Gattei , Jennifer R Brown , Manel Esteller , Emanuele Zucca , Davide Rossi , Francesco Bertoni

ELIOT: A platform to navigate the E3 pocketome and aid the design of new PROTACs.

Chemical biology & drug design

Avec: Tommaso Palomba , Massimo Baroni , Simon Cross , Gabriele Cruciani , Lydia Siragusa

Growth hormone secretagogues modulate inflammation and fibrosis in

Frontiers in immunology

Avec: Brigida Boccanegra , Ornella Cappellari , Paola Mantuano , Daniela Trisciuzzi , Antonietta Mele , Lisamaura Tulimiero , Michela De Bellis , Santa Cirmi , Francesca Sanarica , Alessandro Giovanni Cerchiara , Elena Conte , Ramona Meanti , Laura Rizzi , Elena Bresciani , Severine Denoyelle , Jean-Alain Fehrentz , Gabriele Cruciani , Orazio Nicolotti , Antonella Liantonio , Antonio Torsello , Annamaria De Luca

Targeting protein-protein interactions with low molecular weight and short peptide modulators: insights on disease pathways and starting points for drug discovery.

Expert opinion on drug discovery

Avec: Daniela Trisciuzzi , Bruno O Villoutreix , Lydia Siragusa , Massimo Baroni , Gabriele Cruciani , Orazio Nicolotti

Réseau de co-auteurs

Gabriele Cruciani 21 collaborations

Simon Cross 5 collaborations

Lydia Siragusa 4 collaborations

Massimo Baroni 4 collaborations

Vittorio Lingiardi 4 collaborations

Desirée Bartolini 3 collaborations

Laura Goracci 3 collaborations

Alessandra Di Veroli 3 collaborations

Francesco Galli 3 collaborations

Pietro Zingaretti 3 collaborations

Grazia Fernanda Spitoni 3 collaborations

Giuseppe Cruciani 3 collaborations

Francesca Spyrakis 2 collaborations

Matteo Santucci 2 collaborations

Eleonora Gianquinto 2 collaborations

Alberto Venturelli 2 collaborations

Maria Paola Costi 2 collaborations

Gérald Cruciani 2 collaborations

Rejko Krüger 2 collaborations

Menotti Ruvo 2 collaborations

Danilo Giusepponi 2 collaborations

Roberta Galarini 2 collaborations

Anna Maria Stabile 2 collaborations

Mario Rende 2 collaborations

Marcello Franceschelli 2 collaborations

Emanuele Carosati 2 collaborations

Loriano Storchi 2 collaborations

Guido Giovanardi 2 collaborations

Daniela Trisciuzzi 2 collaborations

Orazio Nicolotti 2 collaborations

Lorenzo Maso 1 collaboration

Filomena Sannio 1 collaboration

Federica Verdirosa 1 collaboration

Filomena De Luca 1 collaboration

Jean-Denis Docquier 1 collaboration

Laura Cendron 1 collaboration

Donatella Tondi 1 collaboration

Nicolo Milani 1 collaboration

NaHong Qiu 1 collaboration

Birgit Molitor 1 collaboration

Justine Badée 1 collaboration

Stephen Fowler 1 collaboration

Ibrahim Boussaad 1 collaboration

Carolin D Obermaier 1 collaboration

Zoé Hanss 1 collaboration

Dheeraj R Bobbili 1 collaboration

Silvia Bolognin 1 collaboration

Enrico Glaab 1 collaboration

Katarzyna Wołyńska 1 collaboration

Nicole Weisschuh 1 collaboration

Laura De Conti 1 collaboration

Caroline May 1 collaboration

Florian Giesert 1 collaboration

Dajana Grossmann 1 collaboration

Annika Lambert 1 collaboration

Susanne Kirchen 1 collaboration

Maria Biryukov 1 collaboration

Lena F Burbulla 1 collaboration

Francois Massart 1 collaboration

Jill Bohler 1 collaboration

Benjamin Schmid 1 collaboration

Annerose Kurz-Drexler 1 collaboration

Patrick May 1 collaboration

Stefano Duga 1 collaboration

Christine Klein 1 collaboration

Jens C Schwamborn 1 collaboration

Katrin Marcus 1 collaboration

Dirk Woitalla 1 collaboration

Daniela M Vogt Weisenhorn 1 collaboration

Wolfgang Wurst 1 collaboration

Marco Baralle 1 collaboration

Dimitri Krainc 1 collaboration

Thomas Gasser 1 collaboration

Bernd Wissinger 1 collaboration

Annamaria Sandomenico 1 collaboration

Andrea Caporale 1 collaboration

Nunzianna Doti 1 collaboration

Angela Chambery 1 collaboration

Sandro De Falco 1 collaboration

Pierangelo Torquato 1 collaboration

Anna Alisi 1 collaboration

Marta Piroddi 1 collaboration

Annalisa Crudele 1 collaboration

Valerio Nobili 1 collaboration

Maurizio Gianni' 1 collaboration

Anna Schlaefli 1 collaboration

Mami Kurosaki 1 collaboration

Luca Guarrera 1 collaboration

Marco Bolis 1 collaboration

Marika Foglia 1 collaboration

Monica Lupi 1 collaboration

Mario P Tschan 1 collaboration

Mineko Terao 1 collaboration

Enrico Garattini 1 collaboration

Anna Gidari 1 collaboration

Samuele Sabbatini 1 collaboration

Sabrina Bastianelli 1 collaboration

Sara Pierucci 1 collaboration

Chiara Busti 1 collaboration

Claudia Monari 1 collaboration

Daniela Francisci 1 collaboration

Giacomo Paglietti 1 collaboration

Giuseppa Tanda 1 collaboration

Rita Teresa Melis 1 collaboration

Anna Musinu 1 collaboration

Carla Cannas 1 collaboration

Valentina Mameli 1 collaboration

Mariano Casu 1 collaboration

Carmine Vacca 1 collaboration

Alessandra Pistilli 1 collaboration

Antimo Gioiello 1 collaboration

Sara Tortorella 1 collaboration

Giulia Sorbi 1 collaboration

Giovanni Bocci 1 collaboration

Roberta Pacifico 1 collaboration

Nunzio Del Gaudio 1 collaboration

Guglielmo Bove 1 collaboration

Lucia Altucci 1 collaboration

Rosa Bellavita 1 collaboration

Paolo Grieco 1 collaboration

Mauro F A Adamo 1 collaboration

Giulia D'Arrigo 1 collaboration

Ida Autiero 1 collaboration

Sergio De Filippis 1 collaboration

Patrick Haggard 1 collaboration

Marco Cavicchioli 1 collaboration

Gaetano Tanzilli 1 collaboration

Annalisa Tanzilli 1 collaboration

Federica Galli 1 collaboration

Matteo Ardit 1 collaboration

Sonia Conte 1 collaboration

Donato Belmonte 1 collaboration

Francesca Menescardi 1 collaboration

Simone Pollastri 1 collaboration

Michele Dondi 1 collaboration

Luca Costantino 1 collaboration

Stefania Ferrari 1 collaboration

Outi M H Salo-Ahen 1 collaboration

Silvia Franchini 1 collaboration

Angela Lauriola 1 collaboration

Cecilia Pozzi 1 collaboration

Matteo Trande 1 collaboration

Gaia Gozzi 1 collaboration

Puneet Saxena 1 collaboration

Giuseppe Cannazza 1 collaboration

Lorena Losi 1 collaboration

Daniela Cardinale 1 collaboration

Antonio Quotadamo 1 collaboration

Pasquale Linciano 1 collaboration

Lorenzo Tagliazucchi 1 collaboration

Maria Gaetana Moschella 1 collaboration

Remo Guerrini 1 collaboration

Salvatore Pacifico 1 collaboration

Rosaria Luciani 1 collaboration

Filippo Genovese 1 collaboration

Stefan Henrich 1 collaboration

Silvia Alboni 1 collaboration

Nuno Santarem 1 collaboration

Anabela da Silva Cordeiro 1 collaboration

Elisa Giovannetti 1 collaboration

Godefridus J Peters 1 collaboration

Paolo Pinton 1 collaboration

Alessandro Rimessi 1 collaboration

Robert M Stroud 1 collaboration

Rebecca C Wade 1 collaboration

Stefano Mangani 1 collaboration

Gaetano Marverti 1 collaboration

Domenico D'Arca 1 collaboration

Glauco Ponterini 1 collaboration

Antonio Galderisi 1 collaboration

Miguel Bravo 1 collaboration

Gianluca Iezzi 1 collaboration

Eleonora Paris 1 collaboration

Jorge de Brito 1 collaboration

Andrea Venturi 1 collaboration

Stefano Di Bona 1 collaboration

Jenny Desantis 1 collaboration

Michela Eleuteri 1 collaboration

Matteo Bartalucci 1 collaboration

Paolo Benedetti 1 collaboration

Maria Quintigliano 1 collaboration

Selene Mezzalira 1 collaboration

Cristiano Scandurra 1 collaboration

Nicola Carone 1 collaboration

Carolina Barola 1 collaboration

Simone Moretti 1 collaboration

Fabiola Paoletti 1 collaboration

Giorgio Saluti 1 collaboration

Gianfranco Brambilla 1 collaboration

Dario Fancello 1 collaboration

Hans-Joachim Massonne 1 collaboration

Antonio Langone 1 collaboration

Massimo Scodina 1 collaboration

Gabriella Antonucci 1 collaboration

Gaspare Galati 1 collaboration

Giulia Titone 1 collaboration

Maddalena Boccia 1 collaboration

Cristina Ottaviani 1 collaboration

Yvonne Martin 1 collaboration

Andy Vinter 1 collaboration

Richard Lewis 1 collaboration

Federico Gago 1 collaboration

Terry R Stouch 1 collaboration

Andrea Gaiardo 1 collaboration

Giulia Zonta 1 collaboration

Sandro Gherardi 1 collaboration

Cesare Malagù 1 collaboration

Barbara Fabbri 1 collaboration

Matteo Valt 1 collaboration

Lia Vanzetti 1 collaboration

Nicolò Landini 1 collaboration

Davide Casotti 1 collaboration

Michele Della Ciana 1 collaboration

Vincenzo Guidi 1 collaboration

Peter A Barbuti 1 collaboration

Jochen Ohnmacht 1 collaboration

Bruno F R Santos 1 collaboration

Paul M Antony 1 collaboration

François Massart 1 collaboration

Claire M Dording 1 collaboration

Lukas Pavelka 1 collaboration

Nicolas Casadei 1 collaboration

Yong-Jun Kwon 1 collaboration

Alberto J Arribas 1 collaboration

Sara Napoli 1 collaboration

Luciano Cascione 1 collaboration

Giulio Sartori 1 collaboration

Laura Barnabei 1 collaboration

Eugenio Gaudio 1 collaboration

Chiara Tarantelli 1 collaboration

Afua Adjeiwaa Mensah 1 collaboration

Filippo Spriano 1 collaboration

Antonella Zucchetto 1 collaboration

Francesca M Rossi 1 collaboration

Andrea Rinaldi 1 collaboration

Manuel Castro de Moura 1 collaboration

Sandra Jovic 1 collaboration

Roberta Bordone-Pittau 1 collaboration

Anastasios Stathis 1 collaboration

Georg Stussi 1 collaboration

Valter Gattei 1 collaboration

Jennifer R Brown 1 collaboration

Manel Esteller 1 collaboration

Emanuele Zucca 1 collaboration

Davide Rossi 1 collaboration

Francesco Bertoni 1 collaboration

Tommaso Palomba 1 collaboration

Brigida Boccanegra 1 collaboration

Ornella Cappellari 1 collaboration

Paola Mantuano 1 collaboration

Antonietta Mele 1 collaboration

Lisamaura Tulimiero 1 collaboration

Michela De Bellis 1 collaboration

Santa Cirmi 1 collaboration

Francesca Sanarica 1 collaboration

Alessandro Giovanni Cerchiara 1 collaboration

Elena Conte 1 collaboration

Ramona Meanti 1 collaboration

Laura Rizzi 1 collaboration

Elena Bresciani 1 collaboration

Severine Denoyelle 1 collaboration

Jean-Alain Fehrentz 1 collaboration

Antonella Liantonio 1 collaboration

Antonio Torsello 1 collaboration

Annamaria De Luca 1 collaboration

Bruno O Villoutreix 1 collaboration