Gerson Peltz

Affiliations

Pfizer Inc., New York, New York, USA.

Publications (22)

Lorlatinib Exposure-Response Analyses for Safety and Efficacy in a Phase I/II Trial to Support Benefit-Risk Assessment in Non-Small Cell Lung Cancer.

Clinical pharmacology and therapeutics

Avec: Joseph Chen , Ana Ruiz-Garcia , Leonard P James , Gerson Peltz , Holger Thurm , Jill Clancy , Jennifer Hibma

The Effect of Population Structure on Murine Genome-Wide Association Studies.

Frontiers in genetics

Avec: Meiyue Wang , Zhuoqing Fang , Boyoung Yoo , Gill Bejerano , Gary Peltz

Ondansetron to reduce neonatal opioid withdrawal severity a randomized clinical trial.

Journal of perinatology : official journal of the California Perinatal Association

Avec: Gary Peltz , Lauren M Jansson , Susan Adeniyi-Jones , Carol Cohane , David Drover , Steven Shafer , Meiyue Wang , Manhong Wu , Balaji Govindaswami , Priya Jegatheesan , Cynthia Argani , Salwa Khan , Walter K Kraft

What Have We Learned (or Expect to) From Analysis of Murine Genetic Models Related to Substance Use Disorders?

Frontiers in psychiatry

Avec: Gary Peltz , Yalun Tan

Brain Penetration of Lorlatinib: Cumulative Incidences of CNS and Non-CNS Progression with Lorlatinib in Patients with Previously Treated ALK-Positive Non-Small-Cell Lung Cancer.

Targeted oncology

Avec: Todd M Bauer , Alice T Shaw , Melissa L Johnson , Alejandro Navarro , Justin F Gainor , Holger Thurm , Yazdi K Pithavala , Antonello Abbattista , Gerson Peltz , Enriqueta Felip

Transcription factor p73 regulates Th1 differentiation.

Nature communications

Avec: Min Ren , Majid Kazemian , Ming Zheng , JianPing He , Peng Li , Jangsuk Oh , Wei Liao , Jessica Li , Jonathan Rajaseelan , Brian L Kelsall , Gary Peltz , Warren J Leonard

Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1-2 trial.

The Lancet. Oncology

Avec: Alice T Shaw , Benjamin J Solomon , Rita Chiari , Gregory J Riely , Benjamin Besse , Ross A Soo , Steven Kao , Chia-Chi Lin , Todd M Bauer , Jill S Clancy , Holger Thurm , Jean-Francois Martini , Gerson Peltz , Antonello Abbattista , Sherry Li , Sai-Hong Ignatius Ou

First-Line Lorlatinib or Crizotinib in Advanced

The New England journal of medicine

Avec: Alice T Shaw , Todd M Bauer , Filippo de Marinis , Enriqueta Felip , Yasushi Goto , Geoffrey Liu , Julien Mazieres , Dong-Wan Kim , Tony Mok , Anna Polli , Holger Thurm , Anna M Calella , Gerson Peltz , Benjamin J Solomon , Auteur inconnu

Intracranial and extracranial efficacy of lorlatinib in patients with ALK-positive non-small-cell lung cancer previously treated with second-generation ALK TKIs.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: E Felip , A T Shaw , A Bearz , D R Camidge , B J Solomon , J R Bauman , T M Bauer , S Peters , F Toffalorio , A Abbattista , H Thurm , G Peltz , R Wiltshire , B Besse

Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward.

The Journal of pharmacology and experimental therapeutics

Avec: Jacob A Beierle , Emily J Yao , Stanley I Goldstein , William B Lynch , Julia L Scotellaro , Anyaa A Shah , Katherine D Sena , Alyssa L Wong , Colton L Linnertz , Olga Averin , David E Moody , Christopher A Reilly , Gary Peltz , Andrew Emili , Martin T Ferris , Camron D Bryant

Engineered Matrices Enable the Culture of Human Patient-Derived Intestinal Organoids.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Daniel R Hunt , Katarina C Klett , Shamik Mascharak , Huiyuan Wang , Diana Gong , Junzhe Lou , Xingnan Li , Pamela C Cai , Riley A Suhar , Julia Y Co , Bauer L LeSavage , Abbygail A Foster , Yuan Guan , Manuel R Amieva , Gary Peltz , Yan Xia , Calvin J Kuo , Sarah C Heilshorn

Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability.

Cancer discovery

Avec: Daniel Thomas , Manhong Wu , Yusuke Nakauchi , Ming Zheng , Chloe A L Thompson-Peach , Kelly Lim , Niklas Landberg , Thomas Köhnke , Nirmal Robinson , Satinder Kaur , Monika Kutyna , Melissa Stafford , Devendra Hiwase , Andreas Reinisch , Gary Peltz , Ravindra Majeti

GSEApy: a comprehensive package for performing gene set enrichment analysis in Python.

Bioinformatics (Oxford, England)

Avec: Zhuoqing Fang , Xinyuan Liu , Gary Peltz

Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results.

Nature medicine

Avec: Kelly C Goldsmith , Julie R Park , Kimberly Kayser , Jemily Malvar , Yueh-Yun Chi , Susan G Groshen , Judith G Villablanca , Kateryna Krytska , Lillian M Lai , Patricia T Acharya , Fariba Goodarzian , Bruce Pawel , Hiroyuki Shimada , Susan Ghazarian , Lisa States , Lynley Marshall , Louis Chesler , Meaghan Granger , Ami V Desai , Rajen Mody , Daniel A Morgenstern , Suzanne Shusterman , Margaret E Macy , Navin Pinto , Gudrun Schleiermacher , Kieuhoa Vo , Holger C Thurm , Joseph Chen , Marlon Liyanage , Gerson Peltz , Katherine K Matthay , Esther R Berko , John M Maris , Araz Marachelian , Yael P Mossé

The phosphatidylethanolamine biosynthesis pathway provides a new target for cancer chemotherapy.

Journal of hepatology

Avec: Yuan Guan , Xinyu Chen , Manhong Wu , Wan Zhu , Ahmed Arslan , Saori Takeda , Mindie H Nguyen , Ravindra Majeti , Dan Thomas , Ming Zheng , Gary Peltz

The Effect of Rifampin on the Pharmacokinetics and Safety of Lorlatinib: Results of a Phase One, Open-Label, Crossover Study in Healthy Participants.

Advances in therapy

Avec: Joseph Chen , Huiping Xu , Sylvester Pawlak , Leonard P James , Gerson Peltz , Kimberly Lee , Katherine Ginman , Michelle Bergeron , Yazdi K Pithavala

Correction to: The Effect of Rifampin on the Pharmacokinetics and Safety of Lorlatinib: Results of a Phase One, Open-Label, Crossover Study in Healthy Participants.

Advances in therapy

Avec: Joseph Chen , Huiping Xu , Sylvester Pawlak , Leonard P James , Gerson Peltz , Kimberly Lee , Katherine Ginman , Michelle Bergeron , Yazdi K Pithavala

Plain language summary of the CROWN study comparing lorlatinib with crizotinib for people with untreated non-small cell lung cancer.

Future oncology (London, England)

Avec: Benjamin J Solomon , Todd M Bauer , Filippo de Marinis , Enriqueta Felip , Yasushi Goto , Geoffrey Liu , Julien Mazieres , Dong-Wan Kim , Tony Mok , Anna Polli , Holger Thurm , Anna Maria Calella , Gerson Peltz , Alice T Shaw

Post Hoc Analysis of Lorlatinib Intracranial Efficacy and Safety in Patients With

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Benjamin J Solomon , Todd M Bauer , Sai-Hong Ignatius Ou , Geoffrey Liu , Hidetoshi Hayashi , Alessandra Bearz , Konstantin Penkov , Yi-Long Wu , Oscar Arrieta , Jacek Jassem , Anna M Calella , Gerson Peltz , Anna Polli , Holger Thurm , Tony Mok

An automated multi-modal graph-based pipeline for mouse genetic discovery.

Bioinformatics (Oxford, England)

Avec: Zhuoqing Fang , Gary Peltz

Preconception opioids interact with mouse strain to alter morphine withdrawal in the next generation.

Psychopharmacology

Avec: Anika Toorie , Claire Davidson Hall , Fair M Vassoler , Gary Peltz , Elizabeth M Byrnes

Analysis of structural variation among inbred mouse strains.

BMC genomics

Avec: Ahmed Arslan , Zhuoqing Fang , Meiyue Wang , Yalun Tan , Zhuanfen Cheng , Xinyu Chen , Yuan Guan , Laura J Pisani , Boyoung Yoo , Gill Bejerano , Gary Peltz

Réseau de co-auteurs

Gary Peltz 12 collaborations

Holger Thurm 6 collaborations

Todd M Bauer 5 collaborations

Joseph Chen 4 collaborations

Zhuoqing Fang 4 collaborations

Alice T Shaw 4 collaborations

Benjamin J Solomon 4 collaborations

Leonard P James 3 collaborations

Meiyue Wang 3 collaborations

Manhong Wu 3 collaborations

Yazdi K Pithavala 3 collaborations

Enriqueta Felip 3 collaborations

Ming Zheng 3 collaborations

Geoffrey Liu 3 collaborations

Tony Mok 3 collaborations

Anna Polli 3 collaborations

Yuan Guan 3 collaborations

Boyoung Yoo 2 collaborations

Gill Bejerano 2 collaborations

Yalun Tan 2 collaborations

Antonello Abbattista 2 collaborations

Sai-Hong Ignatius Ou 2 collaborations

Filippo de Marinis 2 collaborations

Yasushi Goto 2 collaborations

Julien Mazieres 2 collaborations

Dong-Wan Kim 2 collaborations

Anna M Calella 2 collaborations

Ravindra Majeti 2 collaborations

Xinyu Chen 2 collaborations

Ahmed Arslan 2 collaborations

Huiping Xu 2 collaborations

Sylvester Pawlak 2 collaborations

Kimberly Lee 2 collaborations

Katherine Ginman 2 collaborations

Michelle Bergeron 2 collaborations

Ana Ruiz-Garcia 1 collaboration

Jill Clancy 1 collaboration

Jennifer Hibma 1 collaboration

Lauren M Jansson 1 collaboration

Susan Adeniyi-Jones 1 collaboration

Carol Cohane 1 collaboration

David Drover 1 collaboration

Steven Shafer 1 collaboration

Balaji Govindaswami 1 collaboration

Priya Jegatheesan 1 collaboration

Cynthia Argani 1 collaboration

Salwa Khan 1 collaboration

Walter K Kraft 1 collaboration

Melissa L Johnson 1 collaboration

Alejandro Navarro 1 collaboration

Justin F Gainor 1 collaboration

Min Ren 1 collaboration

Majid Kazemian 1 collaboration

JianPing He 1 collaboration

Peng Li 1 collaboration

Jangsuk Oh 1 collaboration

Wei Liao 1 collaboration

Jessica Li 1 collaboration

Jonathan Rajaseelan 1 collaboration

Brian L Kelsall 1 collaboration

Warren J Leonard 1 collaboration

Rita Chiari 1 collaboration

Gregory J Riely 1 collaboration

Benjamin Besse 1 collaboration

Ross A Soo 1 collaboration

Steven Kao 1 collaboration

Chia-Chi Lin 1 collaboration

Jill S Clancy 1 collaboration

Jean-Francois Martini 1 collaboration

Sherry Li 1 collaboration

None None 1 collaboration

E Felip 1 collaboration

A T Shaw 1 collaboration

A Bearz 1 collaboration

D R Camidge 1 collaboration

B J Solomon 1 collaboration

J R Bauman 1 collaboration

T M Bauer 1 collaboration

S Peters 1 collaboration

F Toffalorio 1 collaboration

A Abbattista 1 collaboration

H Thurm 1 collaboration

G Peltz 1 collaboration

R Wiltshire 1 collaboration

B Besse 1 collaboration

Jacob A Beierle 1 collaboration

Emily J Yao 1 collaboration

Stanley I Goldstein 1 collaboration

William B Lynch 1 collaboration

Julia L Scotellaro 1 collaboration

Anyaa A Shah 1 collaboration

Katherine D Sena 1 collaboration

Alyssa L Wong 1 collaboration

Colton L Linnertz 1 collaboration

Olga Averin 1 collaboration

David E Moody 1 collaboration

Christopher A Reilly 1 collaboration

Andrew Emili 1 collaboration

Martin T Ferris 1 collaboration

Camron D Bryant 1 collaboration

Daniel R Hunt 1 collaboration

Katarina C Klett 1 collaboration

Shamik Mascharak 1 collaboration

Huiyuan Wang 1 collaboration

Diana Gong 1 collaboration

Junzhe Lou 1 collaboration

Xingnan Li 1 collaboration

Pamela C Cai 1 collaboration

Riley A Suhar 1 collaboration

Julia Y Co 1 collaboration

Bauer L LeSavage 1 collaboration

Abbygail A Foster 1 collaboration

Manuel R Amieva 1 collaboration

Yan Xia 1 collaboration

Calvin J Kuo 1 collaboration

Sarah C Heilshorn 1 collaboration

Daniel Thomas 1 collaboration

Yusuke Nakauchi 1 collaboration

Chloe A L Thompson-Peach 1 collaboration

Kelly Lim 1 collaboration

Niklas Landberg 1 collaboration

Thomas Köhnke 1 collaboration

Nirmal Robinson 1 collaboration

Satinder Kaur 1 collaboration

Monika Kutyna 1 collaboration

Melissa Stafford 1 collaboration

Devendra Hiwase 1 collaboration

Andreas Reinisch 1 collaboration

Xinyuan Liu 1 collaboration

Kelly C Goldsmith 1 collaboration

Julie R Park 1 collaboration

Kimberly Kayser 1 collaboration

Jemily Malvar 1 collaboration

Yueh-Yun Chi 1 collaboration

Susan G Groshen 1 collaboration

Judith G Villablanca 1 collaboration

Kateryna Krytska 1 collaboration

Lillian M Lai 1 collaboration

Patricia T Acharya 1 collaboration

Fariba Goodarzian 1 collaboration

Bruce Pawel 1 collaboration

Hiroyuki Shimada 1 collaboration

Susan Ghazarian 1 collaboration

Lisa States 1 collaboration

Lynley Marshall 1 collaboration

Louis Chesler 1 collaboration

Meaghan Granger 1 collaboration

Ami V Desai 1 collaboration

Rajen Mody 1 collaboration

Daniel A Morgenstern 1 collaboration

Suzanne Shusterman 1 collaboration

Margaret E Macy 1 collaboration

Navin Pinto 1 collaboration

Gudrun Schleiermacher 1 collaboration

Kieuhoa Vo 1 collaboration

Holger C Thurm 1 collaboration

Marlon Liyanage 1 collaboration

Katherine K Matthay 1 collaboration

Esther R Berko 1 collaboration

John M Maris 1 collaboration

Araz Marachelian 1 collaboration

Yael P Mossé 1 collaboration

Wan Zhu 1 collaboration

Saori Takeda 1 collaboration

Mindie H Nguyen 1 collaboration

Dan Thomas 1 collaboration

Anna Maria Calella 1 collaboration

Hidetoshi Hayashi 1 collaboration

Alessandra Bearz 1 collaboration

Konstantin Penkov 1 collaboration

Yi-Long Wu 1 collaboration

Oscar Arrieta 1 collaboration

Jacek Jassem 1 collaboration

Anika Toorie 1 collaboration

Claire Davidson Hall 1 collaboration

Fair M Vassoler 1 collaboration

Elizabeth M Byrnes 1 collaboration

Zhuanfen Cheng 1 collaboration

Laura J Pisani 1 collaboration