Gerold Bepler

Affiliations

Molecular Therapeutics Program, Department of Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, 4100 John R. Street Detroit, MI 48201, USA.

Publications (16)

HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1.

Cells

Avec: Niko Moses , Mu Zhang , Jheng-Yu Wu , Chen Hu , Shengyan Xiang , Xinran Geng , Yue Chen , Wenlong Bai , You-Wei Zhang , Gerold Bepler , Xiaohong Mary Zhang

Acetylation of MLH1 by CBP increases cellular DNA mismatch repair activity.

Journal of biochemistry

Avec: Mu Zhang , Jiawei Zhao , Peter M Glazer , Wenlong Bai , Gerold Bepler , Xiaohong Mary Zhang

Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC).

Lung cancer (Amsterdam, Netherlands)

Avec: Misako Nagasaka , Mohammad Fahad B Asad , Mohammed Najeeb Al Hallak , Md Hafiz Uddin , Ammar Sukari , Yasmine Baca , Joanne Xiu , Dan Magee , Hirva Mamdani , Dipesh Uprety , Chul Kim , Bing Xia , Stephen V Liu , Jorge J Nieva , Gilberto Lopes , Gerold Bepler , Hossein Borghaei , Michael J Demeure , Luis E Raez , Patrick C Ma , Sonam Puri , W Michael Korn , Asfar S Azmi

Implications of the USP10-HDAC6 axis in lung cancer - A path to precision medicine.

Journal of cancer biology

Avec: Xiaohong Mary Zhang , Navnath Gavande , Prahlad Parajuli , Gerold Bepler

Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Joshua R Heyza , Wen Lei , Donovan Watza , Hao Zhang , Wei Chen , Jessica B Back , Ann G Schwartz , Gerold Bepler , Steve M Patrick

The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.

Cell death & disease

Avec: Chen Hu , Mu Zhang , Niko Moses , Cong-Li Hu , Lisa Polin , Wei Chen , Hyejeong Jang , Joshua Heyza , Agnes Malysa , Joseph A Caruso , Shengyan Xiang , Steve Patrick , Paul Stemmer , Zhenkun Lou , Wenlong Bai , Chuangui Wang , Gerold Bepler , Xiaohong Mary Zhang

Physical activity and quality of life in African American cancer survivors: The Detroit Research on Cancer Survivors study.

Cancer

Avec: Jennifer L Beebe-Dimmer , Julie J Ruterbusch , Felicity W K Harper , Tara M Baird , David G Finlay , Andrew G Rundle , Stephanie S Pandolfi , Theresa A Hastert , Kendra L Schwartz , Gerold Bepler , Michael S Simon , Julia Mantey , Judy Abrams , Teri L Albrecht , Ann G Schwartz

HDAC6 regulates DNA damage response via deacetylating MLH1.

The Journal of biological chemistry

Avec: Mu Zhang , Chen Hu , Niko Moses , Joshua Haakenson , Shengyan Xiang , Daniel Quan , Bin Fang , Zhe Yang , Wenlong Bai , Gerold Bepler , Guo-Min Li , Xiaohong Mary Zhang

A Randomized, Open-Label Phase II Study Evaluating Emibetuzumab Plus Erlotinib and Emibetuzumab Monotherapy in MET Immunohistochemistry Positive NSCLC Patients with Acquired Resistance to Erlotinib.

Clinical lung cancer

Avec: D Ross Camidge , Teresa Moran , Ingel Demedts , Heidrun Grosch , Kathryn Mileham , Julian Molina , Oscar Juan-Vidal , Gerold Bepler , Jonathan W Goldman , Keunchil Park , Johan Wallin , Sameera R Wijayawardana , Xuejing Aimee Wang , Volker Wacheck , Egbert Smit

The Mechanisms of Zinc Action as a Potent Anti-Viral Agent: The Clinical Therapeutic Implication in COVID-19.

Antioxidants (Basel, Switzerland)

Avec: Ananda S Prasad , Agnes Malysa , Gerold Bepler , Andrew Fribley , Bin Bao

ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe.

NAR cancer

Avec: Joshua R Heyza , Elmira Ekinci , Jacob Lindquist , Wen Lei , Christopher Yunker , Vilvanathan Vinothkumar , Rachelle Rowbotham , Lisa Polin , Natalie G Snider , Eric Van Buren , Donovan Watza , Jessica B Back , Wei Chen , Hirva Mamdani , Ann G Schwartz , John J Turchi , Gerold Bepler , Steve M Patrick

Profiling the Mutational Landscape in Known Driver Genes and Novel Genes in African American Non-Small Cell Lung Cancer Patients.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Christine M Lusk , Donovan Watza , Greg Dyson , Douglas Craig , Valerie Ratliff , Angela S Wenzlaff , Fulvio Lonardo , Aliccia Bollig-Fischer , Gerold Bepler , Kristen Purrington , Shirish Gadgeel , Ann G Schwartz

Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer.

Cancer immunology, immunotherapy : CII

Avec: Alberto A Chiappori , Charles C Williams , Jhanelle E Gray , Tawee Tanvetyanon , Eric B Haura , Ben C Creelan , Ram Thapa , Dung-Tsa Chen , George R Simon , Gerold Bepler , Dmitry I Gabrilovich , Scott J Antonia

The Effects of HER2 Alterations in EGFR Mutant Non-small Cell Lung Cancer.

Clinical lung cancer

Avec: Misako Nagasaka , Vijendra Singh , Yasmine Baca , Ammar Sukari , Chul Kim , Hirva Mamdani , Alexander I Spira , Dipesh Uprety , Gerold Bepler , Edward S Kim , Luis E Raez , Sachin Gopalkrishna Pai , Chukwuemeka Ikpeazu , Matthew Oberley , Rebecca Feldman , Joanne Xiu , W Michael Korn , Antoinette J Wozniak , Hossein Borghaei , Stephen V Liu

Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer.

Molecular biomedicine

Avec: Aliccia Bollig-Fischer , Bin Bao , Morenci Manning , Greg Dyson , Sharon K Michelhaugh , Sandeep Mittal , Gerold Bepler , Hirva Mamdani

Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model.

iScience

Avec: Jennifer B Jacob , Kuang-Chung Wei , Gerold Bepler , Joyce D Reyes , Andi Cani , Lisa Polin , Kathryn White , Seongho Kim , Nerissa Viola , Julie McGrath , Anthony Guastella , CongCong Yin , Qing-Shen Mi , Benjamin L Kidder , Kay-Uwe Wagner , Stuart Ratner , Victoria Phillips , Joanne Xiu , Prahlad Parajuli , Wei-Zen Wei

Réseau de co-auteurs

Xiaohong Mary Zhang 5 collaborations

Mu Zhang 4 collaborations

Wenlong Bai 4 collaborations

Hirva Mamdani 4 collaborations

Ann G Schwartz 4 collaborations

Niko Moses 3 collaborations

Chen Hu 3 collaborations

Shengyan Xiang 3 collaborations

Joanne Xiu 3 collaborations

Donovan Watza 3 collaborations

Wei Chen 3 collaborations

Lisa Polin 3 collaborations

Misako Nagasaka 2 collaborations

Ammar Sukari 2 collaborations

Yasmine Baca 2 collaborations

Dipesh Uprety 2 collaborations

Chul Kim 2 collaborations

Stephen V Liu 2 collaborations

Hossein Borghaei 2 collaborations

Luis E Raez 2 collaborations

W Michael Korn 2 collaborations

Prahlad Parajuli 2 collaborations

Joshua R Heyza 2 collaborations

Wen Lei 2 collaborations

Jessica B Back 2 collaborations

Steve M Patrick 2 collaborations

Agnes Malysa 2 collaborations

Bin Bao 2 collaborations

Greg Dyson 2 collaborations

Aliccia Bollig-Fischer 2 collaborations

Jheng-Yu Wu 1 collaboration

Xinran Geng 1 collaboration

Yue Chen 1 collaboration

You-Wei Zhang 1 collaboration

Jiawei Zhao 1 collaboration

Peter M Glazer 1 collaboration

Mohammad Fahad B Asad 1 collaboration

Mohammed Najeeb Al Hallak 1 collaboration

Md Hafiz Uddin 1 collaboration

Dan Magee 1 collaboration

Bing Xia 1 collaboration

Jorge J Nieva 1 collaboration

Gilberto Lopes 1 collaboration

Michael J Demeure 1 collaboration

Patrick C Ma 1 collaboration

Sonam Puri 1 collaboration

Asfar S Azmi 1 collaboration

Navnath Gavande 1 collaboration

Hao Zhang 1 collaboration

Cong-Li Hu 1 collaboration

Hyejeong Jang 1 collaboration

Joshua Heyza 1 collaboration

Joseph A Caruso 1 collaboration

Steve Patrick 1 collaboration

Paul Stemmer 1 collaboration

Zhenkun Lou 1 collaboration

Chuangui Wang 1 collaboration

Jennifer L Beebe-Dimmer 1 collaboration

Julie J Ruterbusch 1 collaboration

Felicity W K Harper 1 collaboration

Tara M Baird 1 collaboration

David G Finlay 1 collaboration

Andrew G Rundle 1 collaboration

Stephanie S Pandolfi 1 collaboration

Theresa A Hastert 1 collaboration

Kendra L Schwartz 1 collaboration

Michael S Simon 1 collaboration

Julia Mantey 1 collaboration

Judy Abrams 1 collaboration

Teri L Albrecht 1 collaboration

Joshua Haakenson 1 collaboration

Daniel Quan 1 collaboration

Bin Fang 1 collaboration

Zhe Yang 1 collaboration

Guo-Min Li 1 collaboration

D Ross Camidge 1 collaboration

Teresa Moran 1 collaboration

Ingel Demedts 1 collaboration

Heidrun Grosch 1 collaboration

Kathryn Mileham 1 collaboration

Julian Molina 1 collaboration

Oscar Juan-Vidal 1 collaboration

Jonathan W Goldman 1 collaboration

Keunchil Park 1 collaboration

Johan Wallin 1 collaboration

Sameera R Wijayawardana 1 collaboration

Xuejing Aimee Wang 1 collaboration

Volker Wacheck 1 collaboration

Egbert Smit 1 collaboration

Ananda S Prasad 1 collaboration

Andrew Fribley 1 collaboration

Elmira Ekinci 1 collaboration

Jacob Lindquist 1 collaboration

Christopher Yunker 1 collaboration

Vilvanathan Vinothkumar 1 collaboration

Rachelle Rowbotham 1 collaboration

Natalie G Snider 1 collaboration

Eric Van Buren 1 collaboration

John J Turchi 1 collaboration

Christine M Lusk 1 collaboration

Douglas Craig 1 collaboration

Valerie Ratliff 1 collaboration

Angela S Wenzlaff 1 collaboration

Fulvio Lonardo 1 collaboration

Kristen Purrington 1 collaboration

Shirish Gadgeel 1 collaboration

Alberto A Chiappori 1 collaboration

Charles C Williams 1 collaboration

Jhanelle E Gray 1 collaboration

Tawee Tanvetyanon 1 collaboration

Eric B Haura 1 collaboration

Ben C Creelan 1 collaboration

Ram Thapa 1 collaboration

Dung-Tsa Chen 1 collaboration

George R Simon 1 collaboration

Dmitry I Gabrilovich 1 collaboration

Scott J Antonia 1 collaboration

Vijendra Singh 1 collaboration

Alexander I Spira 1 collaboration

Edward S Kim 1 collaboration

Sachin Gopalkrishna Pai 1 collaboration

Chukwuemeka Ikpeazu 1 collaboration

Matthew Oberley 1 collaboration

Rebecca Feldman 1 collaboration

Antoinette J Wozniak 1 collaboration

Morenci Manning 1 collaboration

Sharon K Michelhaugh 1 collaboration

Sandeep Mittal 1 collaboration

Jennifer B Jacob 1 collaboration

Kuang-Chung Wei 1 collaboration

Joyce D Reyes 1 collaboration

Andi Cani 1 collaboration

Kathryn White 1 collaboration

Seongho Kim 1 collaboration

Nerissa Viola 1 collaboration

Julie McGrath 1 collaboration

Anthony Guastella 1 collaboration

CongCong Yin 1 collaboration

Qing-Shen Mi 1 collaboration

Benjamin L Kidder 1 collaboration

Kay-Uwe Wagner 1 collaboration

Stuart Ratner 1 collaboration

Victoria Phillips 1 collaboration

Wei-Zen Wei 1 collaboration