George F Widhopf

Affiliations
  • Center for Novel Therapeutics, Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.

Publications (8)

Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism.

Leukemia
Avec: Md Kamrul Hasan , Emanuela M Ghia , Laura Z Rassenti , George F Widhopf , Thomas J Kipps

Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasis.

NPJ breast cancer
Avec: Md Kamrul Hasan , George F Widhopf , Suping Zhang , Sharon M Lam , Zhouxin Shen , Steven P Briggs , Barbara A Parker , Thomas J Kipps

Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells.

Leukemia
Avec: Md Kamrul Hasan , Laura Rassenti , George F Widhopf , Jian Yu , Thomas J Kipps

Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia.

Blood
Avec: Yun Chen , Liguang Chen , Jian Yu , Emanuela M Ghia , Michael Y Choi , Ling Zhang , Suping Zhang , Elsa Sanchez-Lopez , George F Widhopf , Karen Messer , Laura Z Rassenti , Catriona Jamieson , Thomas J Kipps

Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Suping Zhang , Han Zhang , Emanuela M Ghia , Jiajia Huang , Liufeng Wu , Jianchao Zhang , Sharon Lam , Yang Lei , Jinsong He , Bing Cui , George F Widhopf , Jian Yu , Richard Schwab , Karen Messer , Wenqi Jiang , Barbara A Parker , Dennis A Carson , Thomas J Kipps

High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia.

Leukemia
Avec: Emanuela M Ghia , Laura Z Rassenti , Michael Y Choi , Miguel Quijada-Álamo , Elvin Chu , George F Widhopf , Thomas J Kipps

A phase 1b study of zilovertamab in combination with paclitaxel for locally advanced/unresectable or metastatic Her2-negative breast cancer.

Breast cancer research : BCR
Avec: Rebecca A Shatsky , Hemali Batra-Sharma , Teresa Helsten , Richard B Schwab , Emily I Pittman , Minya Pu , Elizabeth Weihe , Emanuela M Ghia , Laura Z Rassenti , Alfredo Molinolo , Betty Cabrera , James B Breitmeyer , George F Widhopf , Karen Messer , Catriona Jamieson , Thomas J Kipps , Barbara A Parker

Variant Transcript of ROR1 ENST00000545203 Does Not Encode ROR1 Protein.

Biomedicines
Avec: Jie Xian , Navyaa Sinha , Christina Girgis , Christopher S Oh , Matthew R Cring , George F Widhopf , Thomas J Kipps

Réseau de co-auteurs

Thomas J Kipps 8 collaborations
Emanuela M Ghia 5 collaborations
Laura Z Rassenti 4 collaborations
Md Kamrul Hasan 3 collaborations
Suping Zhang 3 collaborations
Barbara A Parker 3 collaborations
Jian Yu 3 collaborations
Karen Messer 3 collaborations
Michael Y Choi 2 collaborations
Catriona Jamieson 2 collaborations
Sharon M Lam 1 collaboration
Zhouxin Shen 1 collaboration
Steven P Briggs 1 collaboration
Laura Rassenti 1 collaboration
Yun Chen 1 collaboration
Liguang Chen 1 collaboration
Ling Zhang 1 collaboration
Elsa Sanchez-Lopez 1 collaboration
Han Zhang 1 collaboration
Jiajia Huang 1 collaboration
Liufeng Wu 1 collaboration
Jianchao Zhang 1 collaboration
Sharon Lam 1 collaboration
Yang Lei 1 collaboration
Jinsong He 1 collaboration
Bing Cui 1 collaboration
Richard Schwab 1 collaboration
Wenqi Jiang 1 collaboration
Dennis A Carson 1 collaboration
Miguel Quijada-Álamo 1 collaboration
Elvin Chu 1 collaboration
Rebecca A Shatsky 1 collaboration
Hemali Batra-Sharma 1 collaboration
Teresa Helsten 1 collaboration
Richard B Schwab 1 collaboration
Emily I Pittman 1 collaboration
Minya Pu 1 collaboration
Elizabeth Weihe 1 collaboration
Alfredo Molinolo 1 collaboration
Betty Cabrera 1 collaboration
James B Breitmeyer 1 collaboration
Jie Xian 1 collaboration
Navyaa Sinha 1 collaboration
Christina Girgis 1 collaboration
Christopher S Oh 1 collaboration
Matthew R Cring 1 collaboration