Ganesh Mugundu

Affiliations

Clinical Pharmacology and Quantitative Pharmacology, R&D Clinical Pharmacology and Safety Sciences, AstraZeneca, 35 Gatehouse Drive, Waltham, MA, 02451, USA. ganesh.mugundu@astrazeneca.com.

ORCID: http://orcid.org/0000-0002-3736-1884

Publications (9)

Effect of food on the pharmacokinetics of the WEE1 inhibitor adavosertib (AZD1775) in patients with advanced solid tumors.

Cancer chemotherapy and pharmacology

Avec: Mats Någård , Mei-Lin Ah-See , Karen So , Marit Vermunt , Fiona Thistlethwaite , Mariette Labots , Patricia Roxburgh , Alain Ravaud , Mario Campone , Liselot Valkenburg-van Iersel , Lone Ottesen , Yan Li , Ganesh Mugundu

Comprehensive clinical pharmacology characterization of AZD4635 in healthy participants to support dosing considerations.

British journal of clinical pharmacology

Avec: Ganesh Moorthy , Gayle Pageau Pouliot , Lorraine Graham , Elizabeth Pilling , Lindsey Jung , Rachael Alcobi , Yali Zhu , Yan Li , Sharan Sidhu , Pablo Forte , Ganesh Mugundu

Population pharmacokinetic analysis of danvatirsen supporting flat dosing switch.

Journal of pharmacokinetics and pharmacodynamics

Avec: Hongmei Xu , Xiao Tong , Ganesh Mugundu , Martin L Scott , Carl Cook , Cecilia Arfvidsson , Elizabeth Pease , Diansong Zhou , Paul Lyne , Nidal Al-Huniti

Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Naoko Takebe , Abdul Rafeh Naqash , Geraldine O'Sullivan Coyne , Shivaani Kummar , Khanh Do , Ashley Bruns , Lamin Juwara , Jennifer Zlott , Larry Rubinstein , Richard Piekarz , Elad Sharon , Howard Streicher , Arjun Mittra , Sarah B Miller , Jiuping Ji , Deborah Wilsker , Robert J Kinders , Ralph E Parchment , Li Chen , Ting-Chia Chang , Biswajit Das , Ganesh Mugundu , James H Doroshow , Alice P Chen

A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors.

Targeted oncology

Avec: Todd M Bauer , Kathleen N Moore , Janet S Rader , Fiona Simpkins , Alain C Mita , J Thaddeus Beck , Lowell Hart , Quincy Chu , Amit Oza , Anna V Tinker , Esteban Rodrigo Imedio , Sanjeev Kumar , Ganesh Mugundu , Suzanne Jenkins , Juliann Chmielecki , Suzanne Jones , David Spigel , Siqing Fu

Food Effect Study Design With Oral Drugs: Lessons Learned From Recently Approved Drugs in Oncology.

Journal of clinical pharmacology

Avec: Mark Farha , Eric Masson , Helen Tomkinson , Ganesh Mugundu

Evaluation of Combination Strategies for the A

Frontiers in immunology

Avec: Veronika Voronova , Kirill Peskov , Yuri Kosinsky , Gabriel Helmlinger , Lulu Chu , Alexandra Borodovsky , Richard Woessner , Kris Sachsenmeier , Wenlin Shao , Rakesh Kumar , Gayle Pouliot , Melinda Merchant , Holly Kimko , Ganesh Mugundu

Pharmacokinetics of Lorlatinib After Single and Multiple Dosing in Patients with Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer: Results from a Global Phase I/II Study.

Clinical pharmacokinetics

Avec: Joseph Chen , Melissa T O'Gorman , Lee P James , Karen J Klamerus , Ganesh Mugundu , Yazdi K Pithavala

Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis.

Oncoimmunology

Avec: Boris Shulgin , Yuri Kosinsky , Andrey Omelchenko , Lulu Chu , Ganesh Mugundu , Sergey Aksenov , Rodrigo Pimentel , Garrett DeYulia , Geoffrey Kim , Kirill Peskov , Gabriel Helmlinger

Réseau de co-auteurs

Yan Li 2 collaborations

Kirill Peskov 2 collaborations

Yuri Kosinsky 2 collaborations

Gabriel Helmlinger 2 collaborations

Lulu Chu 2 collaborations

Mats Någård 1 collaboration

Mei-Lin Ah-See 1 collaboration

Karen So 1 collaboration

Marit Vermunt 1 collaboration

Fiona Thistlethwaite 1 collaboration

Mariette Labots 1 collaboration

Patricia Roxburgh 1 collaboration

Alain Ravaud 1 collaboration

Mario Campone 1 collaboration

Liselot Valkenburg-van Iersel 1 collaboration

Lone Ottesen 1 collaboration

Ganesh Moorthy 1 collaboration

Gayle Pageau Pouliot 1 collaboration

Lorraine Graham 1 collaboration

Elizabeth Pilling 1 collaboration

Lindsey Jung 1 collaboration

Rachael Alcobi 1 collaboration

Yali Zhu 1 collaboration

Sharan Sidhu 1 collaboration

Pablo Forte 1 collaboration

Hongmei Xu 1 collaboration

Xiao Tong 1 collaboration

Martin L Scott 1 collaboration

Carl Cook 1 collaboration

Cecilia Arfvidsson 1 collaboration

Elizabeth Pease 1 collaboration

Diansong Zhou 1 collaboration

Paul Lyne 1 collaboration

Nidal Al-Huniti 1 collaboration

Naoko Takebe 1 collaboration

Abdul Rafeh Naqash 1 collaboration

Geraldine O'Sullivan Coyne 1 collaboration

Shivaani Kummar 1 collaboration

Khanh Do 1 collaboration

Ashley Bruns 1 collaboration

Lamin Juwara 1 collaboration

Jennifer Zlott 1 collaboration

Larry Rubinstein 1 collaboration

Richard Piekarz 1 collaboration

Elad Sharon 1 collaboration

Howard Streicher 1 collaboration

Arjun Mittra 1 collaboration

Sarah B Miller 1 collaboration

Jiuping Ji 1 collaboration

Deborah Wilsker 1 collaboration

Robert J Kinders 1 collaboration

Ralph E Parchment 1 collaboration

Li Chen 1 collaboration

Ting-Chia Chang 1 collaboration

Biswajit Das 1 collaboration

James H Doroshow 1 collaboration

Alice P Chen 1 collaboration

Todd M Bauer 1 collaboration

Kathleen N Moore 1 collaboration

Janet S Rader 1 collaboration

Fiona Simpkins 1 collaboration

Alain C Mita 1 collaboration

J Thaddeus Beck 1 collaboration

Lowell Hart 1 collaboration

Quincy Chu 1 collaboration

Amit Oza 1 collaboration

Anna V Tinker 1 collaboration

Esteban Rodrigo Imedio 1 collaboration

Sanjeev Kumar 1 collaboration

Suzanne Jenkins 1 collaboration

Juliann Chmielecki 1 collaboration

Suzanne Jones 1 collaboration

David Spigel 1 collaboration

Siqing Fu 1 collaboration

Mark Farha 1 collaboration

Eric Masson 1 collaboration

Helen Tomkinson 1 collaboration

Veronika Voronova 1 collaboration

Alexandra Borodovsky 1 collaboration

Richard Woessner 1 collaboration

Kris Sachsenmeier 1 collaboration

Wenlin Shao 1 collaboration

Rakesh Kumar 1 collaboration

Gayle Pouliot 1 collaboration

Melinda Merchant 1 collaboration

Holly Kimko 1 collaboration

Joseph Chen 1 collaboration

Melissa T O'Gorman 1 collaboration

Lee P James 1 collaboration

Karen J Klamerus 1 collaboration

Yazdi K Pithavala 1 collaboration

Boris Shulgin 1 collaboration

Andrey Omelchenko 1 collaboration

Sergey Aksenov 1 collaboration

Rodrigo Pimentel 1 collaboration

Garrett DeYulia 1 collaboration

Geoffrey Kim 1 collaboration