G Devonshire

Affiliations

Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.

ORCID: http://orcid.org/0000-0002-1408-8176

Publications (18)

Alterations in the Ca

Exploration of targeted anti-tumor therapy

Avec: Alana L Cutliffe , Sharon L McKenna , Darshan S Chandrashekar , Alvin Ng , Ginny Devonshire , Rebecca C Fitzgerald , Tracey R O'Donovan , John J Mackrill

KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.

Life science alliance

Avec: David Shorthouse , Lizhe Zhuang , Eric P Rahrmann , Cassandra Kosmidou , Katherine Wickham Rahrmann , Michael Hall , Benedict Greenwood , Ginny Devonshire , Richard J Gilbertson , Rebecca C Fitzgerald , Benjamin A Hall

Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction.

International journal of cancer

Avec: Jan Bornschein , Lorenz Wernisch , Maria Secrier , Ahmad Miremadi , Juliane Perner , Shona MacRae , Maria O'Donovan , Richard Newton , Suraj Menon , Lawrence Bower , Matthew D Eldridge , Ginny Devonshire , Calvin Cheah , Richard Turkington , Richard H Hardwick , Michael Selgrad , Marino Venerito , Peter Malfertheiner , Auteur inconnu , Rebecca C Fitzgerald

Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas.

Communications biology

Avec: Alvin Wei Tian Ng , Gianmarco Contino , Sarah Killcoyne , Ginny Devonshire , Ray Hsu , Sujath Abbas , Jing Su , Aisling M Redmond , Jamie M J Weaver , Matthew D Eldridge , Simon Tavaré , Auteur inconnu , Paul A W Edwards , Rebecca C Fitzgerald

SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Kieran Foley , David Shorthouse , Eric Rahrmann , Lizhe Zhuang , Ginny Devonshire , Richard J Gilbertson , Auteur inconnu , Rebecca C Fitzgerald , Benjamin A Hall

The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic.

Nature genetics

Avec: Alexander M Frankell , SriGanesh Jammula , Xiaodun Li , Gianmarco Contino , Sarah Killcoyne , Sujath Abbas , Juliane Perner , Lawrence Bower , Ginny Devonshire , Emma Ococks , Nicola Grehan , James Mok , Maria O'Donovan , Shona MacRae , Matthew D Eldridge , Simon Tavaré , Auteur inconnu , Rebecca C Fitzgerald

Molecular phenotyping reveals the identity of Barrett's esophagus and its malignant transition.

Science (New York, N.Y.)

Avec: Karol Nowicki-Osuch , Lizhe Zhuang , Sriganesh Jammula , Christopher W Bleaney , Krishnaa T Mahbubani , Ginny Devonshire , Annalise Katz-Summercorn , Nils Eling , Anna Wilbrey-Clark , Elo Madissoon , John Gamble , Massimiliano Di Pietro , Maria O'Donovan , Kerstin B Meyer , Kourosh Saeb-Parsy , Andrew D Sharrocks , Sarah A Teichmann , John C Marioni , Rebecca C Fitzgerald

Multi-omic cross-sectional cohort study of pre-malignant Barrett's esophagus reveals early structural variation and retrotransposon activity.

Nature communications

Avec: A C Katz-Summercorn , S Jammula , A Frangou , I Peneva , M O'Donovan , M Tripathi , S Malhotra , M di Pietro , S Abbas , G Devonshire , W Januszewicz , A Blasko , K Nowicki-Osuch , S MacRae , A Northrop , A M Redmond , D C Wedge , R C Fitzgerald

Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett's oesophagus surveillance: individual-level data analysis.

Gut

Avec: Emily L Black , Emma Ococks , Ginny Devonshire , Alvin Wei Tian Ng , Maria O'Donovan , Shalini Malhotra , Monika Tripathi , Ahmad Miremadi , Adam Freeman , Hannah Coles , Auteur inconnu , Rebecca C Fitzgerald

Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia.

Cancer discovery

Avec: Karol Nowicki-Osuch , Lizhe Zhuang , Tik Shing Cheung , Emily L Black , Neus Masqué-Soler , Ginny Devonshire , Aisling M Redmond , Adam Freeman , Massimilliano di Pietro , Nastazja Pilonis , Wladyslaw Januszewicz , Maria O'Donovan , Simon Tavaré , Jacqueline D Shields , Rebecca C Fitzgerald

Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma.

Nature communications

Avec: Sujath Abbas , Oriol Pich , Ginny Devonshire , Shahriar A Zamani , Annalise Katz-Summercorn , Sarah Killcoyne , Calvin Cheah , Barbara Nutzinger , Nicola Grehan , Nuria Lopez-Bigas , Auteur inconnu , Rebecca C Fitzgerald , Maria Secrier

Disentangling oncogenic amplicons in esophageal adenocarcinoma.

Nature communications

Avec: Alvin Wei Tian Ng , Dylan Peter McClurg , Ben Wesley , Shahriar A Zamani , Emily Black , Ahmad Miremadi , Olivier Giger , Rogier Ten Hoopen , Ginny Devonshire , Aisling M Redmond , Nicola Grehan , Sriganesh Jammula , Adrienn Blasko , Xiaodun Li , Samuel Aparicio , Simon Tavaré , Auteur inconnu , Karol Nowicki-Osuch , Rebecca C Fitzgerald

The mutREAD method detects mutational signatures from low quantities of cancer DNA.

Nature communications

Avec: Juliane Perner , Sujath Abbas , Karol Nowicki-Osuch , Ginny Devonshire , Matthew D Eldridge , Simon Tavaré , Rebecca C Fitzgerald

Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data.

Gastroenterology

Avec: SriGanesh Jammula , Annalise C Katz-Summercorn , Xiaodun Li , Constanza Linossi , Elizabeth Smyth , Sarah Killcoyne , Daniele Biasci , Vinod V Subash , Sujath Abbas , Adrienn Blasko , Ginny Devonshire , Amber Grantham , Filip Wronowski , Maria O'Donovan , Nicola Grehan , Matthew D Eldridge , Simon Tavaré , Auteur inconnu , Rebecca C Fitzgerald

The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes.

NAR cancer

Avec: Anastasiya Kazachenka , Jane Hc Loong , Jan Attig , George R Young , Piyali Ganguli , Ginny Devonshire , Nicola Grehan , Auteur inconnu , Francesca D Ciccarelli , Rebecca C Fitzgerald , George Kassiotis

Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments.

Cell death and differentiation

Avec: Stacey J Scott , Xiaodun Li , Sriganesh Jammula , Ginny Devonshire , Catherine Lindon , Rebecca C Fitzgerald , Pier Paolo D'Avino

Longitudinal tracking of 97 esophageal adenocarcinomas using liquid biopsy sampling.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: E Ococks , A M Frankell , N Masque Soler , N Grehan , A Northrop , H Coles , A M Redmond , G Devonshire , J M J Weaver , C Hughes , K Lehovsky , A Blasko , B Nutzinger , Auteur inconnu , R C Fitzgerald , E Smyth

Genomic Analysis of Response to Neoadjuvant Chemotherapy in Esophageal Adenocarcinoma.

Cancers

Avec: Fereshteh Izadi , Benjamin P Sharpe , Stella P Breininger , Maria Secrier , Jane Gibson , Robert C Walker , Saqib Rahman , Ginny Devonshire , Megan A Lloyd , Zoë S Walters , Rebecca C Fitzgerald , Matthew J J Rose-Zerilli , Tim J Underwood , On Behalf Of Occams

Réseau de co-auteurs

Ginny Devonshire 16 collaborations

Rebecca C Fitzgerald 16 collaborations

None None 10 collaborations

Maria O'Donovan 6 collaborations

Simon Tavaré 6 collaborations

Matthew D Eldridge 5 collaborations

Sujath Abbas 5 collaborations

Nicola Grehan 5 collaborations

Lizhe Zhuang 4 collaborations

Sarah Killcoyne 4 collaborations

Xiaodun Li 4 collaborations

Karol Nowicki-Osuch 4 collaborations

Maria Secrier 3 collaborations

Ahmad Miremadi 3 collaborations

Juliane Perner 3 collaborations

Alvin Wei Tian Ng 3 collaborations

Aisling M Redmond 3 collaborations

Sriganesh Jammula 3 collaborations

David Shorthouse 2 collaborations

Richard J Gilbertson 2 collaborations

Benjamin A Hall 2 collaborations

Shona MacRae 2 collaborations

Lawrence Bower 2 collaborations

Calvin Cheah 2 collaborations

Gianmarco Contino 2 collaborations

SriGanesh Jammula 2 collaborations

Emma Ococks 2 collaborations

Annalise Katz-Summercorn 2 collaborations

A Blasko 2 collaborations

A Northrop 2 collaborations

A M Redmond 2 collaborations

R C Fitzgerald 2 collaborations

Emily L Black 2 collaborations

Adam Freeman 2 collaborations

Shahriar A Zamani 2 collaborations

Adrienn Blasko 2 collaborations

Alana L Cutliffe 1 collaboration

Sharon L McKenna 1 collaboration

Darshan S Chandrashekar 1 collaboration

Alvin Ng 1 collaboration

Tracey R O'Donovan 1 collaboration

John J Mackrill 1 collaboration

Eric P Rahrmann 1 collaboration

Cassandra Kosmidou 1 collaboration

Katherine Wickham Rahrmann 1 collaboration

Michael Hall 1 collaboration

Benedict Greenwood 1 collaboration

Jan Bornschein 1 collaboration

Lorenz Wernisch 1 collaboration

Richard Newton 1 collaboration

Suraj Menon 1 collaboration

Richard Turkington 1 collaboration

Richard H Hardwick 1 collaboration

Michael Selgrad 1 collaboration

Marino Venerito 1 collaboration

Peter Malfertheiner 1 collaboration

Ray Hsu 1 collaboration

Jing Su 1 collaboration

Jamie M J Weaver 1 collaboration

Paul A W Edwards 1 collaboration

Kieran Foley 1 collaboration

Eric Rahrmann 1 collaboration

Alexander M Frankell 1 collaboration

James Mok 1 collaboration

Christopher W Bleaney 1 collaboration

Krishnaa T Mahbubani 1 collaboration

Nils Eling 1 collaboration

Anna Wilbrey-Clark 1 collaboration

Elo Madissoon 1 collaboration

John Gamble 1 collaboration

Massimiliano Di Pietro 1 collaboration

Kerstin B Meyer 1 collaboration

Kourosh Saeb-Parsy 1 collaboration

Andrew D Sharrocks 1 collaboration

Sarah A Teichmann 1 collaboration

John C Marioni 1 collaboration

A C Katz-Summercorn 1 collaboration

S Jammula 1 collaboration

A Frangou 1 collaboration

I Peneva 1 collaboration

M O'Donovan 1 collaboration

M Tripathi 1 collaboration

S Malhotra 1 collaboration

M di Pietro 1 collaboration

S Abbas 1 collaboration

W Januszewicz 1 collaboration

K Nowicki-Osuch 1 collaboration

S MacRae 1 collaboration

D C Wedge 1 collaboration

Shalini Malhotra 1 collaboration

Monika Tripathi 1 collaboration

Hannah Coles 1 collaboration

Tik Shing Cheung 1 collaboration

Neus Masqué-Soler 1 collaboration

Massimilliano di Pietro 1 collaboration

Nastazja Pilonis 1 collaboration

Wladyslaw Januszewicz 1 collaboration

Jacqueline D Shields 1 collaboration

Oriol Pich 1 collaboration

Barbara Nutzinger 1 collaboration

Nuria Lopez-Bigas 1 collaboration

Dylan Peter McClurg 1 collaboration

Ben Wesley 1 collaboration

Emily Black 1 collaboration

Olivier Giger 1 collaboration

Rogier Ten Hoopen 1 collaboration

Samuel Aparicio 1 collaboration

Annalise C Katz-Summercorn 1 collaboration

Constanza Linossi 1 collaboration

Elizabeth Smyth 1 collaboration

Daniele Biasci 1 collaboration

Vinod V Subash 1 collaboration

Amber Grantham 1 collaboration

Filip Wronowski 1 collaboration

Anastasiya Kazachenka 1 collaboration

Jane Hc Loong 1 collaboration

Jan Attig 1 collaboration

George R Young 1 collaboration

Piyali Ganguli 1 collaboration

Francesca D Ciccarelli 1 collaboration

George Kassiotis 1 collaboration

Stacey J Scott 1 collaboration

Catherine Lindon 1 collaboration

Pier Paolo D'Avino 1 collaboration

E Ococks 1 collaboration

A M Frankell 1 collaboration

N Masque Soler 1 collaboration

N Grehan 1 collaboration

H Coles 1 collaboration

J M J Weaver 1 collaboration

C Hughes 1 collaboration

K Lehovsky 1 collaboration

B Nutzinger 1 collaboration

E Smyth 1 collaboration

Fereshteh Izadi 1 collaboration

Benjamin P Sharpe 1 collaboration

Stella P Breininger 1 collaboration

Jane Gibson 1 collaboration

Robert C Walker 1 collaboration

Saqib Rahman 1 collaboration

Megan A Lloyd 1 collaboration

Zoë S Walters 1 collaboration

Matthew J J Rose-Zerilli 1 collaboration

Tim J Underwood 1 collaboration

None On Behalf Of Occams 1 collaboration