Frank Narjes

Affiliations

Medicinal Chemistry , Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA) , BioPharmaceuticals R&D , AstraZeneca, Gothenburg , 43183 Mölndal , Sweden.

ORCID: 0000-0002-3104-7771

Publications (9)

Emerging modes-of-action in drug discovery.

MedChemComm

Avec: Eric Valeur , Frank Narjes , Christian Ottmann , Alleyn T Plowright

Automated high-throughput in vitro assays to identify metabolic hotspots and protease stability of structurally diverse, pharmacologically active peptides for inhalation.

Journal of pharmaceutical and biomedical analysis

Avec: Frank Wesche , Leonardo De Maria , Tomas Leek , Frank Narjes , James Bird , Wu Su , Werngard Czechtizky

Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2.

ACS medicinal chemistry letters

Avec: Stefan von Berg , Yafeng Xue , Mia Collins , Antonio Llinas , Roine I Olsson , Torbjörn Halvarsson , Maria Lindskog , Jesper Malmberg , Johan Jirholt , Nina Krutrök , Marie Ramnegård , Marie Brännström , Anders Lundqvist , Matti Lepistö , Anna Aagaard , Jane McPheat , Eva L Hansson , Rongfeng Chen , Yao Xiong , Thomas G Hansson , Frank Narjes

Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations.

Journal of medicinal chemistry

Avec: Igor Shamovsky , Lena Ripa , Frank Narjes , Britta Bonn , Stefan Schiesser , Ina Terstiege , Christian Tyrchan

Kinetic Modeling of PROTAC-Induced Protein Degradation.

ChemMedChem

Avec: Hongtao Zhao , Frank Narjes

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2.

Journal of medicinal chemistry

Avec: Frank Narjes , Antonio Llinas , Stefan von Berg , Johan Jirholt , Sarah Lever , Rikard Pehrson , Mia Collins , Anna Malmberg , Petter Svanberg , Yafeng Xue , Roine I Olsson , Jesper Malmberg , Glyn Hughes , Nafizal Hossain , Hanna Grindebacke , Agnes Leffler , Nina Krutrök , Elisabeth Bäck , Marie Ramnegård , Matti Lepistö , Linda Thunberg , Anna Aagaard , Jane McPheat , Eva L Hansson , Rongfeng Chen , Yao Xiong , Thomas G Hansson

A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.

Chemical science

Avec: Jessica Iegre , Sona Krajcovicova , Anders Gunnarsson , Lisa Wissler , Helena Käck , Anna Luchniak , Stefan Tångefjord , Frank Narjes , David R Spring

Analyzing proteolytic stability and metabolic hotspots of therapeutic peptides in two rodent pulmonary fluids.

Journal of pharmaceutical and biomedical analysis

Avec: Frank Wesche , Leonardo De Maria , Tomas Leek , Frank Narjes , James Bird , Wu Su , Werngard Czechtizky

Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin.

Journal of medicinal chemistry

Avec: Frank Narjes , Fredrik Edfeldt , Jens Petersen , Linda Öster , Corinne Hamblet , James Bird , Peter Bold , Rebecca Rae , Elisabeth Bäck , Stina Stomilovic , Pavol Zlatoidsky , Tor Svensson , Lotta Hidestål , Lavaniya Kunalingam , Igor Shamovsky , Leonardo De Maria , Euan Gordon , Richard J Lewis , Sophie Watcham , Katerine van Rietschoten , Gemma E Mudd , Helen Harrison , Liuhong Chen , Michael J Skynner

Réseau de co-auteurs

Leonardo De Maria 3 collaborations

James Bird 3 collaborations

Frank Wesche 2 collaborations

Tomas Leek 2 collaborations

Wu Su 2 collaborations

Werngard Czechtizky 2 collaborations

Stefan von Berg 2 collaborations

Yafeng Xue 2 collaborations

Mia Collins 2 collaborations

Antonio Llinas 2 collaborations

Roine I Olsson 2 collaborations

Jesper Malmberg 2 collaborations

Johan Jirholt 2 collaborations

Nina Krutrök 2 collaborations

Marie Ramnegård 2 collaborations

Matti Lepistö 2 collaborations

Anna Aagaard 2 collaborations

Jane McPheat 2 collaborations

Eva L Hansson 2 collaborations

Rongfeng Chen 2 collaborations

Yao Xiong 2 collaborations

Thomas G Hansson 2 collaborations

Igor Shamovsky 2 collaborations

Elisabeth Bäck 2 collaborations

Eric Valeur 1 collaboration

Christian Ottmann 1 collaboration

Alleyn T Plowright 1 collaboration

Torbjörn Halvarsson 1 collaboration

Maria Lindskog 1 collaboration

Marie Brännström 1 collaboration

Anders Lundqvist 1 collaboration

Lena Ripa 1 collaboration

Britta Bonn 1 collaboration

Stefan Schiesser 1 collaboration

Ina Terstiege 1 collaboration

Christian Tyrchan 1 collaboration

Hongtao Zhao 1 collaboration

Sarah Lever 1 collaboration

Rikard Pehrson 1 collaboration

Anna Malmberg 1 collaboration

Petter Svanberg 1 collaboration

Glyn Hughes 1 collaboration

Nafizal Hossain 1 collaboration

Hanna Grindebacke 1 collaboration

Agnes Leffler 1 collaboration

Linda Thunberg 1 collaboration

Jessica Iegre 1 collaboration

Sona Krajcovicova 1 collaboration

Anders Gunnarsson 1 collaboration

Lisa Wissler 1 collaboration

Helena Käck 1 collaboration

Anna Luchniak 1 collaboration

Stefan Tångefjord 1 collaboration

David R Spring 1 collaboration

Fredrik Edfeldt 1 collaboration

Jens Petersen 1 collaboration

Linda Öster 1 collaboration

Corinne Hamblet 1 collaboration

Peter Bold 1 collaboration

Rebecca Rae 1 collaboration

Stina Stomilovic 1 collaboration

Pavol Zlatoidsky 1 collaboration

Tor Svensson 1 collaboration

Lotta Hidestål 1 collaboration

Lavaniya Kunalingam 1 collaboration

Euan Gordon 1 collaboration

Richard J Lewis 1 collaboration

Sophie Watcham 1 collaboration

Katerine van Rietschoten 1 collaboration

Gemma E Mudd 1 collaboration

Helen Harrison 1 collaboration

Liuhong Chen 1 collaboration

Michael J Skynner 1 collaboration