Florin Despa

Affiliations

Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky, USA; Department of Neurology, University of Kentucky, Lexington, Kentucky, USA. Electronic address: f.despa@uky.edu.

Publications (16)

Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries.

Kidney international

Avec: Nirmal Verma , Miao Liu , Han Ly , Analia Loria , Kenneth S Campbell , Heather Bush , Philip A Kern , Pedro A Jose , Heinrich Taegtmeyer , Donald M Bers , Sanda Despa , Larry B Goldstein , Andrew J Murray , Florin Despa

Rapid, scalable assay of amylin-β amyloid co-aggregation in brain tissue and blood.

The Journal of biological chemistry

Avec: Deepak Kotiya , Noah Leibold , Nirmal Verma , Gregory A Jicha , Larry B Goldstein , Florin Despa

Gestational diabetes triggers postpartum cardiac hypertrophy via activation of calcineurin/NFAT signaling.

Scientific reports

Avec: Nirmal Verma , Sarah Srodulski , Sathya Velmurugan , Amanda Hoskins , Vivek K Pandey , Florin Despa , Sanda Despa

The association between renal accumulation of pancreatic amyloid-forming amylin and renal hypoxia.

Frontiers in endocrinology

Avec: Nirmal Verma , Florin Despa

Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia.

Journal of lipid and atherosclerosis

Avec: Han Ly , Florin Despa

Amylin Dyshomeostasis Hypothesis: Small Vessel-Type Ischemic Stroke in the Setting of Type-2 Diabetes.

Stroke

Avec: Florin Despa , Larry B Goldstein

Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.

Communications biology

Avec: Nirmal Verma , Gopal Viswanathan Velmurugan , Edric Winford , Han Coburn , Deepak Kotiya , Noah Leibold , Laura Radulescu , Sanda Despa , Kuey C Chen , Linda J Van Eldik , Peter T Nelson , Donna M Wilcock , Gregory A Jicha , Ann M Stowe , Larry B Goldstein , David K Powel , Jeffrey H Walton , Manuel F Navedo , Matthew A Nystoriak , Andrew J Murray , Geert Jan Biessels , Claire Troakes , Henrik Zetterberg , John Hardy , Tammaryn Lashley , Florin Despa

Lower sarcoplasmic reticulum Ca

Heart rhythm

Avec: Iuliana Popescu , Guo Yin , Sathya Velmurugan , Jeffrey R Erickson , Florin Despa , Sanda Despa

The association of circulating amylin with β-amyloid in familial Alzheimer's disease.

Alzheimer's & dementia (New York, N. Y.)

Avec: Han Ly , Nirmal Verma , Savita Sharma , Deepak Kotiya , Sanda Despa , Erin L Abner , Peter T Nelson , Gregory A Jicha , Donna M Wilcock , Larry B Goldstein , Rita Guerreiro , José Brás , Angela J Hanson , Suzanne Craft , Andrew J Murray , Geert Jan Biessels , Claire Troakes , Henrik Zetterberg , John Hardy , Tammaryn Lashley , Aesg , Florin Despa

Contributing Factors to Diabetic Brain Injury and Cognitive Decline.

Diabetes & metabolism journal

Avec: Nirmal Verma , Florin Despa

Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.

Brain pathology (Zurich, Switzerland)

Avec: Pierre De Rossi , Robert J Andrew , Timothy F Musial , Virginie Buggia-Prevot , Guilian Xu , Moorthi Ponnusamy , Han Ly , Sofia V Krause , Richard C Rice , Valentine de l'Estoile , Tess Valin , Someya Salem , Florin Despa , David R Borchelt , Vytas P Bindokas , Daniel A Nicholson , Gopal Thinakaran

Bloodborne Pancreatic Amylin, A Therapeutic Target for Alzheimer's Disease.

Current Alzheimer research

Avec: Florin Despa

Neuroinflammation induced by amyloid-forming pancreatic amylin: Rationale for a mechanistic hypothesis.

Biophysical chemistry

Avec: Noah S Leibold , Florin Despa

Type-2 Diabetes, Pancreatic Amylin, and Neuronal Metabolic Remodeling in Alzheimer's Disease.

Molecular nutrition & food research

Avec: Noah Leibold , James R Bain , Florin Despa

Distinct Effects of Mitochondrial Na

Journal of the American Heart Association

Avec: Sathya Velmurugan , Ting Liu , Kuey C Chen , Florin Despa , Brian O'Rourke , Sanda Despa

Skin capillary amylin deposition resembles brain amylin vasculopathy in rats.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Avec: Saurav Das , Nirmal Verma , Larry B Goldstein , Florin Despa

Réseau de co-auteurs

Nirmal Verma 8 collaborations

Sanda Despa 6 collaborations

Larry B Goldstein 6 collaborations

Han Ly 4 collaborations

Andrew J Murray 3 collaborations

Deepak Kotiya 3 collaborations

Noah Leibold 3 collaborations

Gregory A Jicha 3 collaborations

Sathya Velmurugan 3 collaborations

Kuey C Chen 2 collaborations

Peter T Nelson 2 collaborations

Donna M Wilcock 2 collaborations

Geert Jan Biessels 2 collaborations

Claire Troakes 2 collaborations

Henrik Zetterberg 2 collaborations

John Hardy 2 collaborations

Tammaryn Lashley 2 collaborations

Miao Liu 1 collaboration

Analia Loria 1 collaboration

Kenneth S Campbell 1 collaboration

Heather Bush 1 collaboration

Philip A Kern 1 collaboration

Pedro A Jose 1 collaboration

Heinrich Taegtmeyer 1 collaboration

Donald M Bers 1 collaboration

Sarah Srodulski 1 collaboration

Amanda Hoskins 1 collaboration

Vivek K Pandey 1 collaboration

Gopal Viswanathan Velmurugan 1 collaboration

Edric Winford 1 collaboration

Han Coburn 1 collaboration

Laura Radulescu 1 collaboration

Linda J Van Eldik 1 collaboration

Ann M Stowe 1 collaboration

David K Powel 1 collaboration

Jeffrey H Walton 1 collaboration

Manuel F Navedo 1 collaboration

Matthew A Nystoriak 1 collaboration

Iuliana Popescu 1 collaboration

Guo Yin 1 collaboration

Jeffrey R Erickson 1 collaboration

Savita Sharma 1 collaboration

Erin L Abner 1 collaboration

Rita Guerreiro 1 collaboration

José Brás 1 collaboration

Angela J Hanson 1 collaboration

Suzanne Craft 1 collaboration

None Aesg 1 collaboration

Pierre De Rossi 1 collaboration

Robert J Andrew 1 collaboration

Timothy F Musial 1 collaboration

Virginie Buggia-Prevot 1 collaboration

Guilian Xu 1 collaboration

Moorthi Ponnusamy 1 collaboration

Sofia V Krause 1 collaboration

Richard C Rice 1 collaboration

Valentine de l'Estoile 1 collaboration

Tess Valin 1 collaboration

Someya Salem 1 collaboration

David R Borchelt 1 collaboration

Vytas P Bindokas 1 collaboration

Daniel A Nicholson 1 collaboration

Gopal Thinakaran 1 collaboration

Noah S Leibold 1 collaboration

James R Bain 1 collaboration

Ting Liu 1 collaboration

Brian O'Rourke 1 collaboration

Saurav Das 1 collaboration