Fernando L Palhano

Affiliations

Programa de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Publications (20)

From reporters to endogenous genes: the impact of the first five codons on translation efficiency in

RNA biology

Avec: Mariana H Moreira , Géssica C Barros , Rodrigo D Requião , Silvana Rossetto , Tatiana Domitrovic , Fernando L Palhano

Inflammatory profiling of patients with familial amyloid polyneuropathy.

BMC neurology

Avec: Estefania P Azevedo , Anderson B Guimaraes-Costa , Christianne Bandeira-Melo , Leila Chimelli , Marcia Waddington-Cruz , Elvira M Saraiva , Fernando L Palhano , Debora Foguel

Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases.

Frontiers in neuroscience

Avec: Luiza Fernandes , Thyago R Cardim-Pires , Debora Foguel , Fernando L Palhano

Influence of nascent polypeptide positive charges on translation dynamics.

The Biochemical journal

Avec: Rodrigo D Requião , Géssica C Barros , Tatiana Domitrovic , Fernando L Palhano

Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis.

Scientific reports

Avec: Priscila Ausina , Jessica R Branco , Thainá M Demaria , Amanda M Esteves , João Gabriel B Leandro , Alan C Ochioni , Ana Paula M Mendonça , Fernando L Palhano , Marcus F Oliveira , Wassim Abou-Kheir , Mauro Sola-Penna , Patricia Zancan

New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding.

Journal of the American Heart Association

Avec: Leonardo Maciel , Dahienne Ferreira de Oliveira , Fernanda Mesquita , Hercules Antônio da Silva Souza , Leandro Oliveira , Michelle Lopes Araújo Christie , Fernando L Palhano , Antônio Carlos Campos de Carvalho , José Hamilton Matheus Nascimento , Debora Foguel

JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species.

Neurotoxicity research

Avec: Cleonice Creusa Santos , Thyago R Cardim-Pires , Liana Shvachiy , Luis Arturo Fonseca-Fonseca , Patricia Muñoz , Áurea Maria A N Almeida , Ana Carla S Costa , Jéssica Teles-Souza , Estael Ochoa-Rodríguez , Maria de Fátima Dias Costa , Fernando L Palhano , Juan Segura-Aguilar , Deyse B Barbosa , Mayra R do Bomfim , Manoelito C Dos Santos Junior , Franco Henrique A Leite , Samuel Silva da Rocha Pita , Silvia Lima Costa , Yanier Núñez-Figueredo , Tiago Fleming Outeiro , Débora Foguel , Victor Diogenes Amaral Silva

How oxidized EGCG remodels α-synuclein fibrils into non-toxic aggregates: insights from computational simulations.

Physical chemistry chemical physics : PCCP

Avec: Priscila Baltazar Gonçalves , Fernando L Palhano , Yraima Cordeiro , Ana Carolina Rennó Sodero

Rqc1 and other yeast proteins containing highly positively charged sequences are not targets of the RQC complex.

The Journal of biological chemistry

Avec: Géssica C Barros , Rodrigo D Requião , Rodolfo L Carneiro , Claudio A Masuda , Mariana H Moreira , Silvana Rossetto , Tatiana Domitrovic , Fernando L Palhano

A systematic structural comparison of all solved small proteins deposited in PDB. The effect of disulfide bonds in protein fold.

Computational and structural biotechnology journal

Avec: Mariana H Moreira , Fabio C L Almeida , Tatiana Domitrovic , Fernando L Palhano

Structural and thermodynamic characterization of a highly amyloidogenic dimer of transthyretin involved in a severe cardiomyopathy.

The Journal of biological chemistry

Avec: Lucas do Amaral Martins , Priscila S Ferreira , Otávio Augusto Leitão Dos Santos , Leticia Oliveira Martins , Luiz Gabriel Cabral Fernandes Barroso , Humberto M Pereira , Márcia Waddington-Cruz , Fernando Lucas Palhano , Debora Foguel

Green Tea Polyphenol Microparticles Based on the Oxidative Coupling of EGCG Inhibit Amyloid Aggregation/Cytotoxicity and Serve as a Platform for Drug Delivery.

ACS biomaterials science & engineering

Avec: Luiza Fernandes , Beatriz Messias , Antonio Pereira-Neves , Estefania P Azevedo , Júlia Araújo , Debora Foguel , Fernando L Palhano

Natural variation of the cardiac transcriptome in humans.

RNA biology

Avec: Tatiana Domitrovic , Mariana H Moreira , Rodolfo L Carneiro , Marcelo Ribeiro-Alves , Fernando L Palhano

Codon stabilization coefficient as a metric to gain insights into mRNA stability and codon bias and their relationships with translation.

Nucleic acids research

Avec: Rodolfo L Carneiro , Rodrigo D Requião , Silvana Rossetto , Tatiana Domitrovic , Fernando L Palhano

Viruses with different genome types adopt a similar strategy to pack nucleic acids based on positively charged protein domains.

Scientific reports

Avec: Rodrigo D Requião , Rodolfo L Carneiro , Mariana Hoyer Moreira , Marcelo Ribeiro-Alves , Silvana Rossetto , Fernando L Palhano , Tatiana Domitrovic

Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Katrina Albert , Diana P Raymundo , Anne Panhelainen , Ave Eesmaa , Liana Shvachiy , Gabriela R Araújo , Piotr Chmielarz , Xu Yan , Aastha Singh , Yraima Cordeiro , Fernando L Palhano , Debora Foguel , Kelvin C Luk , Andrii Domanskyi , Merja H Voutilainen , Henri J Huttunen , Tiago F Outeiro , Mart Saarma , Marcius S Almeida , Mikko Airavaara

Pentameric Thiophene as a Probe to Monitor EGCG's Remodeling Activity of Mature Amyloid Fibrils: Overcoming Signal Artifacts of Thioflavin T.

ACS omega

Avec: Mirian Kelley , Ricardo Sant'Anna , Luiza Fernandes , Fernando L Palhano

Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells.

Scientific reports

Avec: Otávio Augusto Leitão Dos Santos , Rodolfo L Carneiro , Rodrigo D Requião , Marcelo Ribeiro-Alves , Tatiana Domitrovic , Fernando L Palhano

A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Daniela D Queiroz , Thales de P Ribeiro , Julliana M Gonçalves , Larissa M M Mattos , Ellen Gerhardt , Júlia Freitas , Fernando L Palhano , Susana Frases , Anderson S Pinheiro , Malachy McCann , Andrew Knox , Michael Devereux , Tiago F Outeiro , Marcos D Pereira

Enhancing anti-amyloidogenic properties and antioxidant effects of Scutellaria baicalensis polyphenols through novel nanoparticle formation.

International journal of biological macromolecules

Avec: Shirin Jalili , Mohammad Panji , Mohsen Mahdavimehr , Ali Mohseni Ahangar , Hadi Shirzad , Seyed Amin Mousavi Nezhad , Fernando L Palhano

Réseau de co-auteurs

Tatiana Domitrovic 8 collaborations

Rodrigo D Requião 6 collaborations

Debora Foguel 6 collaborations

Rodolfo L Carneiro 5 collaborations

Mariana H Moreira 4 collaborations

Silvana Rossetto 4 collaborations

Géssica C Barros 3 collaborations

Luiza Fernandes 3 collaborations

Marcelo Ribeiro-Alves 3 collaborations

Estefania P Azevedo 2 collaborations

Thyago R Cardim-Pires 2 collaborations

Liana Shvachiy 2 collaborations

Yraima Cordeiro 2 collaborations

Otávio Augusto Leitão Dos Santos 2 collaborations

Tiago F Outeiro 2 collaborations

Anderson B Guimaraes-Costa 1 collaboration

Christianne Bandeira-Melo 1 collaboration

Leila Chimelli 1 collaboration

Marcia Waddington-Cruz 1 collaboration

Elvira M Saraiva 1 collaboration

Priscila Ausina 1 collaboration

Jessica R Branco 1 collaboration

Thainá M Demaria 1 collaboration

Amanda M Esteves 1 collaboration

João Gabriel B Leandro 1 collaboration

Alan C Ochioni 1 collaboration

Ana Paula M Mendonça 1 collaboration

Marcus F Oliveira 1 collaboration

Wassim Abou-Kheir 1 collaboration

Mauro Sola-Penna 1 collaboration

Patricia Zancan 1 collaboration

Leonardo Maciel 1 collaboration

Dahienne Ferreira de Oliveira 1 collaboration

Fernanda Mesquita 1 collaboration

Hercules Antônio da Silva Souza 1 collaboration

Leandro Oliveira 1 collaboration

Michelle Lopes Araújo Christie 1 collaboration

Antônio Carlos Campos de Carvalho 1 collaboration

José Hamilton Matheus Nascimento 1 collaboration

Cleonice Creusa Santos 1 collaboration

Luis Arturo Fonseca-Fonseca 1 collaboration

Patricia Muñoz 1 collaboration

Áurea Maria A N Almeida 1 collaboration

Ana Carla S Costa 1 collaboration

Jéssica Teles-Souza 1 collaboration

Estael Ochoa-Rodríguez 1 collaboration

Maria de Fátima Dias Costa 1 collaboration

Juan Segura-Aguilar 1 collaboration

Deyse B Barbosa 1 collaboration

Mayra R do Bomfim 1 collaboration

Manoelito C Dos Santos Junior 1 collaboration

Franco Henrique A Leite 1 collaboration

Samuel Silva da Rocha Pita 1 collaboration

Silvia Lima Costa 1 collaboration

Yanier Núñez-Figueredo 1 collaboration

Tiago Fleming Outeiro 1 collaboration

Débora Foguel 1 collaboration

Victor Diogenes Amaral Silva 1 collaboration

Priscila Baltazar Gonçalves 1 collaboration

Ana Carolina Rennó Sodero 1 collaboration

Claudio A Masuda 1 collaboration

Fabio C L Almeida 1 collaboration

Lucas do Amaral Martins 1 collaboration

Priscila S Ferreira 1 collaboration

Leticia Oliveira Martins 1 collaboration

Luiz Gabriel Cabral Fernandes Barroso 1 collaboration

Humberto M Pereira 1 collaboration

Márcia Waddington-Cruz 1 collaboration

Fernando Lucas Palhano 1 collaboration

Beatriz Messias 1 collaboration

Antonio Pereira-Neves 1 collaboration

Júlia Araújo 1 collaboration

Mariana Hoyer Moreira 1 collaboration

Katrina Albert 1 collaboration

Diana P Raymundo 1 collaboration

Anne Panhelainen 1 collaboration

Ave Eesmaa 1 collaboration

Gabriela R Araújo 1 collaboration

Piotr Chmielarz 1 collaboration

Xu Yan 1 collaboration

Aastha Singh 1 collaboration

Kelvin C Luk 1 collaboration

Andrii Domanskyi 1 collaboration

Merja H Voutilainen 1 collaboration

Henri J Huttunen 1 collaboration

Mart Saarma 1 collaboration

Marcius S Almeida 1 collaboration

Mikko Airavaara 1 collaboration

Mirian Kelley 1 collaboration

Ricardo Sant'Anna 1 collaboration

Daniela D Queiroz 1 collaboration

Thales de P Ribeiro 1 collaboration

Julliana M Gonçalves 1 collaboration

Larissa M M Mattos 1 collaboration

Ellen Gerhardt 1 collaboration

Júlia Freitas 1 collaboration

Susana Frases 1 collaboration

Anderson S Pinheiro 1 collaboration

Malachy McCann 1 collaboration

Andrew Knox 1 collaboration

Michael Devereux 1 collaboration

Marcos D Pereira 1 collaboration

Shirin Jalili 1 collaboration

Mohammad Panji 1 collaboration

Mohsen Mahdavimehr 1 collaboration

Ali Mohseni Ahangar 1 collaboration

Hadi Shirzad 1 collaboration

Seyed Amin Mousavi Nezhad 1 collaboration