F Meurens

Affiliations

BIOEPAR, INRAE, ONIRIS, Nantes, France.

Publications (45)

How the Innate Immune DNA Sensing cGAS-STING Pathway Is Involved in Autophagy.

International journal of molecular sciences

Avec: Wanglong Zheng , Nengwen Xia , Jiajia Zhang , Nanhua Chen , François Meurens , Zongping Liu , Jianzhong Zhu

African Swine Fever Virus A528R Inhibits TLR8 Mediated NF-κB Activity by Targeting p65 Activation and Nuclear Translocation.

Viruses

Avec: Xueliang Liu , Da Ao , Sen Jiang , Nengwen Xia , Yulin Xu , Qi Shao , Jia Luo , Heng Wang , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

Flu RNA Vaccine: A Game Changer?

Vaccines

Avec: François Meurens

The African swine fever virus protease pS273R inhibits DNA sensing cGAS-STING pathway by targeting IKKε.

Virulence

Avec: Jia Luo , Jiajia Zhang , Jinghua Ni , Sen Jiang , Nengwen Xia , Yiwen Guo , Qi Shao , Qi Cao , Wanglong Zheng , Nanhua Chen , Quan Zhang , Hongjun Chen , Qing Chen , Hongfei Zhu , François Meurens , Jianzhong Zhu

Rapid Visual Detection of African Swine Fever Virus with a CRISPR/Cas12a Lateral Flow Strip Based on Structural Protein Gene D117L.

Animals : an open access journal from MDPI

Avec: Desheng Zhang , Sen Jiang , Nengwen Xia , Youwen Zhang , Jiajia Zhang , Anjing Liu , Chenyang Zhang , Nanhua Chen , Francois Meurens , Wanglong Zheng , Jianzhong Zhu

CD163-Expressing Porcine Macrophages Support NADC30-like and NADC34-like PRRSV Infections.

Viruses

Avec: Yulin Xu , Mengxue Ye , Shaohua Sun , Qi Cao , Jia Luo , Yuening Wang , Wanglong Zheng , François Meurens , Nanhua Chen , Jianzhong Zhu

Porcine IKKε is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway.

The Journal of biological chemistry

Avec: Jia Luo , Qi Cao , Jiajia Zhang , Sen Jiang , Nengwen Xia , Shaohua Sun , Wanglong Zheng , Nanhua Chen , Francois Meurens , Jianzhong Zhu

Comparative transcriptome analysis of TLR8 signaling cells revealed the porcine TLR8 specific differentially expressed genes.

Developmental and comparative immunology

Avec: Da Ao , Pengpeng Xia , Sen Jiang , Nanhua Chen , François Meurens , Jianzhong Zhu

Porcine IFI16 Negatively Regulates cGAS Signaling Through the Restriction of DNA Binding and Stimulation.

Frontiers in immunology

Avec: Wanglong Zheng , Rongyun Zhou , Shuangjie Li , Shan He , Jia Luo , Meiqin Zhu , Nanhua Chen , Hongjun Chen , François Meurens , Jianzhong Zhu

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2.

Frontiers in immunology

Avec: Shuangjie Li , Jie Yang , Yuanyuan Zhu , Hui Wang , Xingyu Ji , Jia Luo , Qi Shao , Yulin Xu , Xueliang Liu , Wanglong Zheng , François Meurens , Nanhua Chen , Jianzhong Zhu

Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses.

Frontiers in microbiology

Avec: Shuangjie Li , Qi Shao , Yuanyuan Zhu , Xingyu Ji , Jia Luo , Yulin Xu , Xueliang Liu , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

The Internal Conduit System of the Swine Inverted Lymph Node.

Frontiers in immunology

Avec: Laurence Dubreil , Mireille Ledevin , Caroline Hervet , Déborah Menard , Claire Philippe , François J Michel , Thibaut Larcher , François Meurens , Nicolas Bertho

Impact of swine influenza A virus on porcine reproductive and respiratory syndrome virus infection in alveolar macrophages.

Frontiers in veterinary science

Avec: Janaïna Grevelinger , Olivier Bourry , François Meurens , Aline Perrin , Caroline Hervet , Laurence Dubreil , Gaëlle Simon , Nicolas Bertho

Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions.

Vaccines

Avec: Shuangjie Li , Jie Yang , Yuanyuan Zhu , Xingyu Ji , Kun Wang , Sen Jiang , Jia Luo , Hui Wang , Wanglong Zheng , Nanhua Chen , Jianqiang Ye , François Meurens , Jianzhong Zhu

IPEC-1 variable immune response to different serovars of Salmonella enterica subsp. enterica.

Veterinary immunology and immunopathology

Avec: Mustapha Berri , Daniel Hogan , Georges Saade , Sylvie Roche , Philippe Velge , Isabelle Virlogeux-Payant , François Meurens

The signaling relations between three adaptors of porcine C-type lectin receptor pathway.

Developmental and comparative immunology

Avec: Sen Jiang , Da Ao , Jinghua Ni , Nanhua Chen , François Meurens , Jianzhong Zhu

Porcine Reproductive and Respiratory Syndrome Virus Interferes with Swine Influenza A Virus Infection of Epithelial Cells.

Vaccines

Avec: Georges Saade , Déborah Ménard , Caroline Hervet , Patricia Renson , Erika Hue , Jianzhong Zhu , Laurence Dubreil , Romain Paillot , Stéphane Pronost , Olivier Bourry , Gaëlle Simon , Joëlle Dupont , Nicolas Bertho , François Meurens

Inter-relation analysis of signaling adaptors of porcine innate immune pathways.

Molecular immunology

Avec: Da Ao , Shuangjie Li , Sen Jiang , Jia Luo , Nanhua Chen , François Meurens , Jianzhong Zhu

The pig as a medical model for acquired respiratory diseases and dysfunctions: An immunological perspective.

Molecular immunology

Avec: Nicolas Bertho , François Meurens

Multiple Porcine Innate Immune Signaling Pathways Are Involved in the Anti-PEDV Response.

Viruses

Avec: Youwen Zhang , Yulin Xu , Sen Jiang , Shaohua Sun , Jiajia Zhang , Jia Luo , Qi Cao , Wanglong Zheng , François Meurens , Nanhua Chen , Jianzhong Zhu

How the Innate Immune DNA Sensing cGAS-STING Pathway Is Involved in Apoptosis.

International journal of molecular sciences

Avec: Wanglong Zheng , Anjing Liu , Nengwen Xia , Nanhua Chen , François Meurens , Jianzhong Zhu

Prospecting potential links between PRRSV infection susceptibility of alveolar macrophages and other respiratory infectious agents present in conventionally reared pigs.

Veterinary immunology and immunopathology

Avec: L Museau , C Hervet , G Saade , D Menard , C Belloc , F Meurens , N Bertho

Coinfections and their molecular consequences in the porcine respiratory tract.

Veterinary research

Avec: Georges Saade , Céline Deblanc , Juliette Bougon , Corinne Marois-Créhan , Christelle Fablet , Gaël Auray , Catherine Belloc , Mily Leblanc-Maridor , Carl A Gagnon , Jianzhong Zhu , Marcelo Gottschalk , Artur Summerfield , Gaëlle Simon , Nicolas Bertho , François Meurens

Assessment of pulmonary tissue responses in pigs challenged with PRRSV Lena strain shows better protection after immunization with field than vaccine strains.

Veterinary microbiology

Avec: Thibaut Larcher , Christelle Fablet , Patricia Renson , Déborah Ménard , Caroline Hervet , Georges Saade , Catherine Belloc , Olivier Bourry , François Meurens

African Swine Fever Virus Structural Protein p17 Inhibits Cell Proliferation through ER Stress-ROS Mediated Cell Cycle Arrest.

Viruses

Avec: Nengwen Xia , Hui Wang , Xueliang Liu , Qi Shao , Da Ao , Yulin Xu , Sen Jiang , Jia Luo , Jiajia Zhang , Nanhua Chen , François Meurens , Wanglong Zheng , Jianzhong Zhu

Animal board invited review: Risks of zoonotic disease emergence at the interface of wildlife and livestock systems.

Animal : an international journal of animal bioscience

Avec: François Meurens , Charlotte Dunoyer , Christine Fourichon , Volker Gerdts , Nadia Haddad , Jeroen Kortekaas , Marta Lewandowska , Elodie Monchatre-Leroy , Artur Summerfield , Paul J Wichgers Schreur , Wim H M van der Poel , Jianzhong Zhu

Appeasing Pheromones against Bovine Respiratory Complex and Modulation of Immune Transcript Expressions.

Animals : an open access journal from MDPI

Avec: Caroline Hervet , Justine Boullier , Marlène Guiadeur , Léa Michel , Laure Brun-Lafleur , Anne Aupiais , Jianzhong Zhu , Béatrice Mounaix , François Meurens , Fanny Renois , Sébastien Assié

Screening of Porcine Innate Immune Adaptor Signaling Revealed Several Anti-PRRSV Signaling Pathways.

Vaccines

Avec: Yulin Xu , Mengxue Ye , Youwen Zhang , Shaohua Sun , Jia Luo , Sen Jiang , Jiajia Zhang , Xueliang Liu , Qi Shao , Qi Cao , Wanglong Zheng , François Meurens , Nanhua Chen , Jianzhong Zhu

African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.

Frontiers in immunology

Avec: Wanglong Zheng , Nengwen Xia , Jiajia Zhang , Qi Cao , Sen Jiang , Jia Luo , Hui Wang , Nanhua Chen , Quan Zhang , François Meurens , Jianzhong Zhu

SARS-CoV-2 Vaccination: What Can We Expect Now?

Vaccines

Avec: François Meurens , Fanny Renois , Alexis Bouin , Jianzhong Zhu

Marine-Sulfated Polysaccharides Extracts Exhibit Contrasted Time-Dependent Immunomodulatory and Antiviral Properties on Porcine Monocytes and Alveolar Macrophages.

Animals : an open access journal from MDPI

Avec: Caroline Hervet , Frédérick Bussy , Claude Le Goff , Déborah Ménard , Pi Nyvall Collén , Matthieu Le Goff , François Meurens , Nicolas Bertho

[Viral co-infections targeting the porcine respiratory system: Consequences and limits of the experimental systems].

Virologie (Montrouge, France)

Avec: François Meurens , Jianzhong Zhu , Fanny Renois

Systematic analysis of the codon usage patterns of African swine fever virus genome coding sequences reveals its host adaptation phenotype.

Microbial genomics

Avec: Yuening Wang , Chenglin Chi , Jiajia Zhang , Kaili Zhang , Dafu Deng , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication

Frontiers in veterinary science

Avec: Benoît Levast , Daniel Hogan , Jill van Kessel , Stacy Strom , Stew Walker , Jianzhong Zhu , François Meurens , Volker Gerdts

Effectiveness of two intranasal vaccines for the control of bovine respiratory disease in newborn beef calves: A randomized non-inferiority multicentre field trial.

Veterinary journal (London, England : 1997)

Avec: N Masset , F Meurens , M Marie , P Lesage , A Lehébel , N Brisseau , S Assié

Identification of imidazoquinoline derivative (IQD) interacting sites of porcine TLR8 and the underlying species specificity.

Molecular immunology

Avec: Da Ao , Xueliang Liu , Pengpeng Xia , Hui Wang , Sen Jiang , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function.

Viruses

Avec: Yulin Xu , Youwen Zhang , Shaohua Sun , Jia Luo , Sen Jiang , Jiajia Zhang , Xueliang Liu , Qi Shao , Qi Cao , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

The Signal Peptide and Chaperone UNC93B1 Both Influence TLR8 Ectodomain Intracellular Endosomal Localization.

Vaccines

Avec: Da Ao , Xueliang Liu , Sen Jiang , Yulin Xu , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

The Porcine and Chicken Innate DNA Sensing cGAS-STING-IRF Signaling Axes Exhibit Differential Species Specificity.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Sen Jiang , Jia Luo , Youwen Zhang , Qi Cao , Yuening Wang , Nengwen Xia , Wanglong Zheng , Nanhua Chen , François Meurens , Huiguang Wu , Jianzhong Zhu

Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.

Frontiers in immunology

Avec: Nengwen Xia , Wanglong Zheng , Sen Jiang , Qi Cao , Jia Luo , Jiajia Zhang , Yulin Xu , Shaohua Sun , Kaili Zhang , Nanhua Chen , François Meurens , Jianzhong Zhu

Human and animal botulism surveillance in France from 2008 to 2019.

Frontiers in public health

Avec: Sophie Le Bouquin , Camille Lucas , Rozenn Souillard , Caroline Le Maréchal , Karine Petit , Pauline Kooh , Nathalie Jourdan-Da Silva , François Meurens , Laurent Guillier , Christelle Mazuet

The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy.

Journal of virology

Avec: Sen Jiang , Nengwen Xia , Jia Luo , Youwen Zhang , Qi Cao , Jiajia Zhang , Yuening Wang , Yuan Zhao , Wanglong Zheng , Nanhua Chen , François Meurens , Xiangdong Li , Jianzhong Zhu

Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner.

Viruses

Avec: Shaohua Sun , Yulin Xu , Ming Qiu , Sen Jiang , Qi Cao , Jia Luo , Tangjie Zhang , Nanhua Chen , Wanglong Zheng , Francois Meurens , Zongping Liu , Jianzhong Zhu

The Chicken cGAS-STING Pathway Exerts Interferon-Independent Antiviral Function via Cell Apoptosis.

Animals : an open access journal from MDPI

Avec: Sen Jiang , Mengjia Lv , Desheng Zhang , Qi Cao , Nengwen Xia , Jia Luo , Wanglong Zheng , Nanhua Chen , François Meurens , Jianzhong Zhu

How Does cGAS Avoid Sensing Self-DNA under Normal Physiological Conditions?

International journal of molecular sciences

Avec: Wangli Zheng , Nanhua Chen , François Meurens , Wanglong Zheng , Jianzhong Zhu

Réseau de co-auteurs

François Meurens 40 collaborations

Jianzhong Zhu 35 collaborations

Nanhua Chen 28 collaborations

Wanglong Zheng 25 collaborations

Sen Jiang 20 collaborations

Jia Luo 19 collaborations

Nengwen Xia 12 collaborations

Jiajia Zhang 12 collaborations

Qi Cao 12 collaborations

Yulin Xu 11 collaborations

Xueliang Liu 8 collaborations

Da Ao 7 collaborations

Qi Shao 7 collaborations

Shaohua Sun 7 collaborations

Youwen Zhang 6 collaborations

Caroline Hervet 6 collaborations

Nicolas Bertho 6 collaborations

Shuangjie Li 5 collaborations

Hui Wang 5 collaborations

Yuening Wang 4 collaborations

Georges Saade 4 collaborations

Francois Meurens 3 collaborations

Yuanyuan Zhu 3 collaborations

Xingyu Ji 3 collaborations

Laurence Dubreil 3 collaborations

Olivier Bourry 3 collaborations

Gaëlle Simon 3 collaborations

Déborah Ménard 3 collaborations

Fanny Renois 3 collaborations

Zongping Liu 2 collaborations

Jinghua Ni 2 collaborations

Quan Zhang 2 collaborations

Hongjun Chen 2 collaborations

Desheng Zhang 2 collaborations

Anjing Liu 2 collaborations

Mengxue Ye 2 collaborations

Pengpeng Xia 2 collaborations

Jie Yang 2 collaborations

Thibaut Larcher 2 collaborations

Daniel Hogan 2 collaborations

Patricia Renson 2 collaborations

Christelle Fablet 2 collaborations

Catherine Belloc 2 collaborations

Artur Summerfield 2 collaborations

Volker Gerdts 2 collaborations

Kaili Zhang 2 collaborations

Heng Wang 1 collaboration

Yiwen Guo 1 collaboration

Qing Chen 1 collaboration

Hongfei Zhu 1 collaboration

Chenyang Zhang 1 collaboration

Rongyun Zhou 1 collaboration

Shan He 1 collaboration

Meiqin Zhu 1 collaboration

Mireille Ledevin 1 collaboration

Déborah Menard 1 collaboration

Claire Philippe 1 collaboration

François J Michel 1 collaboration

Janaïna Grevelinger 1 collaboration

Aline Perrin 1 collaboration

Kun Wang 1 collaboration

Jianqiang Ye 1 collaboration

Mustapha Berri 1 collaboration

Sylvie Roche 1 collaboration

Philippe Velge 1 collaboration

Isabelle Virlogeux-Payant 1 collaboration

Erika Hue 1 collaboration

Romain Paillot 1 collaboration

Stéphane Pronost 1 collaboration

Joëlle Dupont 1 collaboration

L Museau 1 collaboration

C Hervet 1 collaboration

G Saade 1 collaboration

D Menard 1 collaboration

C Belloc 1 collaboration

N Bertho 1 collaboration

Céline Deblanc 1 collaboration

Juliette Bougon 1 collaboration

Corinne Marois-Créhan 1 collaboration

Gaël Auray 1 collaboration

Mily Leblanc-Maridor 1 collaboration

Carl A Gagnon 1 collaboration

Marcelo Gottschalk 1 collaboration

Charlotte Dunoyer 1 collaboration

Christine Fourichon 1 collaboration

Nadia Haddad 1 collaboration

Jeroen Kortekaas 1 collaboration

Marta Lewandowska 1 collaboration

Elodie Monchatre-Leroy 1 collaboration

Paul J Wichgers Schreur 1 collaboration

Wim H M van der Poel 1 collaboration

Justine Boullier 1 collaboration

Marlène Guiadeur 1 collaboration

Léa Michel 1 collaboration

Laure Brun-Lafleur 1 collaboration

Anne Aupiais 1 collaboration

Béatrice Mounaix 1 collaboration

Sébastien Assié 1 collaboration

Alexis Bouin 1 collaboration

Frédérick Bussy 1 collaboration

Claude Le Goff 1 collaboration

Pi Nyvall Collén 1 collaboration

Matthieu Le Goff 1 collaboration

Chenglin Chi 1 collaboration

Dafu Deng 1 collaboration

Benoît Levast 1 collaboration

Jill van Kessel 1 collaboration

Stacy Strom 1 collaboration

Stew Walker 1 collaboration

N Masset 1 collaboration

M Marie 1 collaboration

P Lesage 1 collaboration

A Lehébel 1 collaboration

N Brisseau 1 collaboration

S Assié 1 collaboration

Huiguang Wu 1 collaboration

Sophie Le Bouquin 1 collaboration

Camille Lucas 1 collaboration

Rozenn Souillard 1 collaboration

Caroline Le Maréchal 1 collaboration

Karine Petit 1 collaboration

Pauline Kooh 1 collaboration

Nathalie Jourdan-Da Silva 1 collaboration

Laurent Guillier 1 collaboration

Christelle Mazuet 1 collaboration

Yuan Zhao 1 collaboration

Xiangdong Li 1 collaboration

Ming Qiu 1 collaboration

Tangjie Zhang 1 collaboration

Mengjia Lv 1 collaboration

Wangli Zheng 1 collaboration