Eric R Goedken

Affiliations

Discovery Dermatology & Fibrosis , AbbVie Bioresearch Center , Worcester , Massachusetts 01605 , United States.

Publications (6)

Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses.

ACS chemical biology

Avec: Peter F Slivka , Chen-Lin Hsieh , Alex Lipovsky , Steven D Pratt , John Locklear , Marian T Namovic , Heath A McDonald , Joseph Wetter , Rebecca Edelmayer , Min Hu , Erin Murphy , Marc Domanus , Charles Lu , Ryan Duggan , Jacob King , Victoria E Scott , Diana Donnelly-Roberts , Anthony Slavin , Sujatha Gopalakrishnan , Namjin Chung , Eric R Goedken

ACT1 Is Required for Murine IL-23-Induced Psoriasiform Inflammation Potentially Independent of E3 Ligase Activity.

The Journal of investigative dermatology

Avec: Alex Lipovsky , Peter F Slivka , Zhi Su , Yibing Wang , Stephanie Paulsboe , Joseph Wetter , Marian T Namovic , Donna Gauvin , Denise Perron , Stephen B Gauld , Steven McGaraughty , Eric R Goedken

Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site.

Scientific reports

Avec: Eric R Goedken , Maria A Argiriadi , Justin D Dietrich , Andrew M Petros , Navasona Krishnan , Sanjay C Panchal , Wei Qiu , Haihong Wu , Haizhong Zhu , Ashley M Adams , Pierre M Bodelle , Lucas Goguen , Paul L Richardson , Peter F Slivka , Myron Srikumaran , Anup K Upadhyay , Bainan Wu , Russell A Judge , Anil Vasudevan , Sujatha M Gopalakrishnan , Philip B Cox , Vincent S Stoll , Chaohong Sun

ABBV-105, a selective and irreversible inhibitor of Bruton's tyrosine kinase, is efficacious in multiple preclinical models of inflammation.

Modern rheumatology

Avec: Christian Goess , Christopher M Harris , Sara Murdock , Richard W McCarthy , Erik Sampson , Rachel Twomey , Suzanne Mathieu , Regina Mario , Matthew Perham , Eric R Goedken , Andrew J Long

Importance of PLD2 in an IL-23 driven psoriasiform dermatitis model and potential link to human psoriasis.

The Journal of dermatology

Avec: Zhi Su , Peter Slivka , Stephanie Paulsboe , Katherine Chu , Joseph B Wetter , Marian Namovic , Denise Perron , Arun Kannan , Qi Wan , Charlene Manning , Viktor Todorovic , Kathleen M Smith , Alex Lipovsky , Yibing Wang , Kristine Frank , Steve McGaraughty , Jacqueline Loud , Victoria E Scott , Prisca Honore , Eric R Goedken

Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.

Journal of medicinal chemistry

Avec: Ashley L Ramos , Eric R Goedken , Kristine E Frank , Maria A Argiriadi , Sana Bazzaz , Zhiguo Bian , Jesse T C Brown , Paolo A Centrella , Hui-Ju Chen , Jeremy S Disch , Pamela L Donner , David B Duignan , Diana Gikunju , Stephen N Greszler , Marie-Aude Guié , Sevan Habeshian , Hajnalka E Hartl , Christopher D Hein , Charles W Hutchins , Rachael Jetson , Anthony D Keefe , Hasan Khan , Huan-Qiu Li , Allison Olszewski , Benjamin J Ortiz Cardona , Augustine Osuma , Sanjay C Panchal , Ryan Phelan , Wei Qiu , J Brad Shotwell , Anurupa Shrestha , Myron Srikumaran , Zhi Su , Chaohong Sun , Anup K Upadhyay , Michael D Wood , Haihong Wu , Ruijie Zhang , Ying Zhang , Gang Zhao , Haizhong Zhu , Matthew P Webster

Réseau de co-auteurs

Peter F Slivka 3 collaborations

Alex Lipovsky 3 collaborations

Zhi Su 3 collaborations

Marian T Namovic 2 collaborations

Joseph Wetter 2 collaborations

Victoria E Scott 2 collaborations

Yibing Wang 2 collaborations

Stephanie Paulsboe 2 collaborations

Denise Perron 2 collaborations

Maria A Argiriadi 2 collaborations

Sanjay C Panchal 2 collaborations

Wei Qiu 2 collaborations

Haihong Wu 2 collaborations

Haizhong Zhu 2 collaborations

Myron Srikumaran 2 collaborations

Anup K Upadhyay 2 collaborations

Chaohong Sun 2 collaborations

Chen-Lin Hsieh 1 collaboration

Steven D Pratt 1 collaboration

John Locklear 1 collaboration

Heath A McDonald 1 collaboration

Rebecca Edelmayer 1 collaboration

Min Hu 1 collaboration

Erin Murphy 1 collaboration

Marc Domanus 1 collaboration

Charles Lu 1 collaboration

Ryan Duggan 1 collaboration

Jacob King 1 collaboration

Diana Donnelly-Roberts 1 collaboration

Anthony Slavin 1 collaboration

Sujatha Gopalakrishnan 1 collaboration

Namjin Chung 1 collaboration

Donna Gauvin 1 collaboration

Stephen B Gauld 1 collaboration

Steven McGaraughty 1 collaboration

Justin D Dietrich 1 collaboration

Andrew M Petros 1 collaboration

Navasona Krishnan 1 collaboration

Ashley M Adams 1 collaboration

Pierre M Bodelle 1 collaboration

Lucas Goguen 1 collaboration

Paul L Richardson 1 collaboration

Bainan Wu 1 collaboration

Russell A Judge 1 collaboration

Anil Vasudevan 1 collaboration

Sujatha M Gopalakrishnan 1 collaboration

Philip B Cox 1 collaboration

Vincent S Stoll 1 collaboration

Christian Goess 1 collaboration

Christopher M Harris 1 collaboration

Sara Murdock 1 collaboration

Richard W McCarthy 1 collaboration

Erik Sampson 1 collaboration

Rachel Twomey 1 collaboration

Suzanne Mathieu 1 collaboration

Regina Mario 1 collaboration

Matthew Perham 1 collaboration

Andrew J Long 1 collaboration

Peter Slivka 1 collaboration

Katherine Chu 1 collaboration

Joseph B Wetter 1 collaboration

Marian Namovic 1 collaboration

Arun Kannan 1 collaboration

Qi Wan 1 collaboration

Charlene Manning 1 collaboration

Viktor Todorovic 1 collaboration

Kathleen M Smith 1 collaboration

Kristine Frank 1 collaboration

Steve McGaraughty 1 collaboration

Jacqueline Loud 1 collaboration

Prisca Honore 1 collaboration

Ashley L Ramos 1 collaboration

Kristine E Frank 1 collaboration

Sana Bazzaz 1 collaboration

Zhiguo Bian 1 collaboration

Jesse T C Brown 1 collaboration

Paolo A Centrella 1 collaboration

Hui-Ju Chen 1 collaboration

Jeremy S Disch 1 collaboration

Pamela L Donner 1 collaboration

David B Duignan 1 collaboration

Diana Gikunju 1 collaboration

Stephen N Greszler 1 collaboration

Marie-Aude Guié 1 collaboration

Sevan Habeshian 1 collaboration

Hajnalka E Hartl 1 collaboration

Christopher D Hein 1 collaboration

Charles W Hutchins 1 collaboration

Rachael Jetson 1 collaboration

Anthony D Keefe 1 collaboration

Hasan Khan 1 collaboration

Huan-Qiu Li 1 collaboration

Allison Olszewski 1 collaboration

Benjamin J Ortiz Cardona 1 collaboration

Augustine Osuma 1 collaboration

Ryan Phelan 1 collaboration

J Brad Shotwell 1 collaboration

Anurupa Shrestha 1 collaboration

Michael D Wood 1 collaboration

Ruijie Zhang 1 collaboration

Ying Zhang 1 collaboration

Gang Zhao 1 collaboration

Matthew P Webster 1 collaboration