Didier Mazel

Affiliations

Unité Plasticité du Génome Bactérien, Département Génomes et Génétique, Institut Pasteur, Paris, France. didier.mazel@pasteur.fr.
CNRS, UMR3525, Paris, France. didier.mazel@pasteur.fr.

Publications (26)

Integron Identification in Bacterial Genomes and Cassette Recombination Assays.

Methods in molecular biology (Clifton, N.J.)

Avec: Claire Vit , Céline Loot , José Antonio Escudero , Aleksandra Nivina , Didier Mazel

Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae.

PLoS genetics

Avec: André Carvalho , Didier Mazel , Zeynep Baharoglu

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eLife

Avec: Anamaria Babosan , David Skurnik , Anaëlle Muggeo , Gerald B Pier , Zeynep Baharoglu , Thomas Jové , Marie-Cécile Ploy , Sophie Griveau , Fethi Bedioui , Sébastien Vergnolle , Sophie Moussalih , Christophe de Champs , Didier Mazel , Thomas Guillard

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions.

eLife

Avec: José Antonio Escudero , Aleksandra Nivina , Harry E Kemble , Céline Loot , Olivier Tenaillon , Didier Mazel

Sleeping ribosomes: Bacterial signaling triggers RaiA mediated persistence to aminoglycosides.

iScience

Avec: Manon Lang , Evelyne Krin , Chloé Korlowski , Odile Sismeiro , Hugo Varet , Jean-Yves Coppée , Didier Mazel , Zeynep Baharoglu

Increasing the Scalability of Toxin-Intein Orthogonal Combinations.

ACS synthetic biology

Avec: Rocío López-Igual , Pedro Dorado-Morales , Didier Mazel

Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae.

BMC biology

Avec: Alfonso Soler-Bistué , Sebastián Aguilar-Pierlé , Marc Garcia-Garcerá , Marie-Eve Val , Odile Sismeiro , Hugo Varet , Rodrigo Sieira , Evelyne Krin , Ole Skovgaard , Diego J Comerci , Eduardo P C Rocha , Didier Mazel

Structure-specific DNA recombination sites: Design, validation, and machine learning-based refinement.

Science advances

Avec: Aleksandra Nivina , Maj Svea Grieb , Céline Loot , David Bikard , Jean Cury , Laila Shehata , Juliana Bernardes , Didier Mazel

Enhanced emergence of antibiotic-resistant pathogenic bacteria after in vitro induction with cancer chemotherapy drugs.

The Journal of antimicrobial chemotherapy

Avec: Alexandre Meunier , Virginie Nerich , Christine Fagnoni-Legat , Marion Richard , Didier Mazel , Olivier Adotevi , Xavier Bertrand , Didier Hocquet

Engineered toxin-intein antimicrobials can selectively target and kill antibiotic-resistant bacteria in mixed populations.

Nature biotechnology

Avec: Rocío López-Igual , Joaquín Bernal-Bayard , Alfonso Rodríguez-Patón , Jean-Marc Ghigo , Didier Mazel

Unbridled Integrons: A Matter of Host Factors.

Cells

Avec: Egill Richard , Baptiste Darracq , Céline Loot , Didier Mazel

Identification of the active mechanism of aminoglycoside entry in

bioRxiv : the preprint server for biology

Avec: Sebastian A Pierlé , Manon Lang , Rocío López-Igual , Evelyne Krin , Dominique Fourmy , Sean P Kennedy , Marie-Eve Val , Zeynep Baharoglu , Didier Mazel

Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules.

Microbiology and molecular biology reviews : MMBR

Avec: Manon Lang , André Carvalho , Zeynep Baharoglu , Didier Mazel

Measuring single-cell susceptibility to antibiotics within monoclonal bacterial populations.

PloS one

Avec: Lena Le Quellec , Andrey Aristov , Salomé Gutiérrez Ramos , Gabriel Amselem , Julia Bos , Zeynep Baharoglu , Didier Mazel , Charles N Baroud

Metagenomic strategies identify diverse integron-integrase and antibiotic resistance genes in the Antarctic environment.

MicrobiologyOpen

Avec: Verónica Antelo , Matías Giménez , Gastón Azziz , Patricia Valdespino-Castillo , Luisa I Falcón , Lucas A M Ruberto , Walter P Mac Cormack , Didier Mazel , Silvia Batista

Insertion Sequences Determine Plasmid Adaptation to New Bacterial Hosts.

mBio

Avec: Emilia Wedel , Cristina Bernabe-Balas , Manuel Ares-Arroyo , Natalia Montero , Alfonso Santos-Lopez , Didier Mazel , Bruno Gonzalez-Zorn

Nonessential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress.

microLife

Avec: Anamaria Babosan , Louna Fruchard , Evelyne Krin , André Carvalho , Didier Mazel , Zeynep Baharoglu

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems.

Science advances

Avec: Egill Richard , Baptiste Darracq , Eloi Littner , Claire Vit , Clémence Whiteway , Julia Bos , Florian Fournes , Geneviève Garriss , Valentin Conte , Delphine Lapaillerie , Vincent Parissi , François Rousset , Ole Skovgaard , David Bikard , Eduardo P C Rocha , Didier Mazel , Céline Loot

Chromosomal integrons are genetically and functionally isolated units of genomes.

Nucleic acids research

Avec: Paula Blanco , Filipa Trigo da Roza , Laura Toribio-Celestino , Lucía García-Pastor , Niccolò Caselli , Álvaro Morón , Francisco Ojeda , Baptiste Darracq , Ester Vergara , Francisco Amaro , Álvaro San Millán , Ole Skovgaard , Didier Mazel , Céline Loot , José Antonio Escudero

RadD Contributes to R-Loop Avoidance in Sub-MIC Tobramycin.

mBio

Avec: Veronica Negro , Evelyne Krin , Sebastian Aguilar Pierlé , Thibault Chaze , Quentin Giai Gianetto , Sean P Kennedy , Mariette Matondo , Didier Mazel , Zeynep Baharoglu

Interplay between Sublethal Aminoglycosides and Quorum Sensing: Consequences on Survival in

Cells

Avec: André Carvalho , Evelyne Krin , Chloé Korlowski , Didier Mazel , Zeynep Baharoglu

Comparative Genomics of Synechococcus elongatus Explains the Phenotypic Diversity of the Strains.

mBio

Avec: Marie Adomako , Dustin Ernst , Ryan Simkovsky , Yi-Yun Chao , Jingtong Wang , Mingxu Fang , Christiane Bouchier , Rocio Lopez-Igual , Didier Mazel , Muriel Gugger , Susan S Golden

Chromosomal Position of Ribosomal Protein Genes Affects Long-Term Evolution of Vibrio cholerae.

mBio

Avec: Leticia Larotonda , Damien Mornico , Varun Khanna , Joaquín Bernal-Bayard , Jean-Marc Ghigo , Marie-Eve Val , Diego Comerci , Didier Mazel , Alfonso Soler-Bistué

Unlocking the potential of microbiome editing: A review of conjugation-based delivery.

Molecular microbiology

Avec: Pedro Dorado-Morales , Morgan Lambérioux , Didier Mazel

RavA-ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in

Microbiology spectrum

Avec: Evelyne Krin , André Carvalho , Manon Lang , Anamaria Babosan , Didier Mazel , Zeynep Baharoglu

Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites.

Nature microbiology

Avec: Céline Loot , Gael A Millot , Egill Richard , Eloi Littner , Claire Vit , Frédéric Lemoine , Bertrand Néron , Jean Cury , Baptiste Darracq , Théophile Niault , Delphine Lapaillerie , Vincent Parissi , Eduardo P C Rocha , Didier Mazel

Réseau de co-auteurs

Zeynep Baharoglu 10 collaborations

Céline Loot 7 collaborations

Evelyne Krin 7 collaborations

André Carvalho 5 collaborations

Manon Lang 4 collaborations

Baptiste Darracq 4 collaborations

Claire Vit 3 collaborations

José Antonio Escudero 3 collaborations

Aleksandra Nivina 3 collaborations

Anamaria Babosan 3 collaborations

Rocío López-Igual 3 collaborations

Marie-Eve Val 3 collaborations

Ole Skovgaard 3 collaborations

Eduardo P C Rocha 3 collaborations

Egill Richard 3 collaborations

Chloé Korlowski 2 collaborations

Odile Sismeiro 2 collaborations

Hugo Varet 2 collaborations

Pedro Dorado-Morales 2 collaborations

Alfonso Soler-Bistué 2 collaborations

David Bikard 2 collaborations

Jean Cury 2 collaborations

Joaquín Bernal-Bayard 2 collaborations

Jean-Marc Ghigo 2 collaborations

Sean P Kennedy 2 collaborations

Julia Bos 2 collaborations

Eloi Littner 2 collaborations

Delphine Lapaillerie 2 collaborations

Vincent Parissi 2 collaborations

David Skurnik 1 collaboration

Anaëlle Muggeo 1 collaboration

Gerald B Pier 1 collaboration

Thomas Jové 1 collaboration

Marie-Cécile Ploy 1 collaboration

Sophie Griveau 1 collaboration

Fethi Bedioui 1 collaboration

Sébastien Vergnolle 1 collaboration

Sophie Moussalih 1 collaboration

Christophe de Champs 1 collaboration

Thomas Guillard 1 collaboration

Harry E Kemble 1 collaboration

Olivier Tenaillon 1 collaboration

Jean-Yves Coppée 1 collaboration

Sebastián Aguilar-Pierlé 1 collaboration

Marc Garcia-Garcerá 1 collaboration

Rodrigo Sieira 1 collaboration

Diego J Comerci 1 collaboration

Maj Svea Grieb 1 collaboration

Laila Shehata 1 collaboration

Juliana Bernardes 1 collaboration

Alexandre Meunier 1 collaboration

Virginie Nerich 1 collaboration

Christine Fagnoni-Legat 1 collaboration

Marion Richard 1 collaboration

Olivier Adotevi 1 collaboration

Xavier Bertrand 1 collaboration

Didier Hocquet 1 collaboration

Alfonso Rodríguez-Patón 1 collaboration

Sebastian A Pierlé 1 collaboration

Dominique Fourmy 1 collaboration

Lena Le Quellec 1 collaboration

Andrey Aristov 1 collaboration

Salomé Gutiérrez Ramos 1 collaboration

Gabriel Amselem 1 collaboration

Charles N Baroud 1 collaboration

Verónica Antelo 1 collaboration

Matías Giménez 1 collaboration

Gastón Azziz 1 collaboration

Patricia Valdespino-Castillo 1 collaboration

Luisa I Falcón 1 collaboration

Lucas A M Ruberto 1 collaboration

Walter P Mac Cormack 1 collaboration

Silvia Batista 1 collaboration

Emilia Wedel 1 collaboration

Cristina Bernabe-Balas 1 collaboration

Manuel Ares-Arroyo 1 collaboration

Natalia Montero 1 collaboration

Alfonso Santos-Lopez 1 collaboration

Bruno Gonzalez-Zorn 1 collaboration

Louna Fruchard 1 collaboration

Clémence Whiteway 1 collaboration

Florian Fournes 1 collaboration

Geneviève Garriss 1 collaboration

Valentin Conte 1 collaboration

François Rousset 1 collaboration

Paula Blanco 1 collaboration

Filipa Trigo da Roza 1 collaboration

Laura Toribio-Celestino 1 collaboration

Lucía García-Pastor 1 collaboration

Niccolò Caselli 1 collaboration

Álvaro Morón 1 collaboration

Francisco Ojeda 1 collaboration

Ester Vergara 1 collaboration

Francisco Amaro 1 collaboration

Álvaro San Millán 1 collaboration

Veronica Negro 1 collaboration

Sebastian Aguilar Pierlé 1 collaboration

Thibault Chaze 1 collaboration

Quentin Giai Gianetto 1 collaboration

Mariette Matondo 1 collaboration

Marie Adomako 1 collaboration

Dustin Ernst 1 collaboration

Ryan Simkovsky 1 collaboration

Yi-Yun Chao 1 collaboration

Jingtong Wang 1 collaboration

Mingxu Fang 1 collaboration

Christiane Bouchier 1 collaboration

Rocio Lopez-Igual 1 collaboration

Muriel Gugger 1 collaboration

Susan S Golden 1 collaboration

Leticia Larotonda 1 collaboration

Damien Mornico 1 collaboration

Varun Khanna 1 collaboration

Diego Comerci 1 collaboration

Morgan Lambérioux 1 collaboration

Gael A Millot 1 collaboration

Frédéric Lemoine 1 collaboration

Bertrand Néron 1 collaboration

Théophile Niault 1 collaboration